{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:41:13Z","timestamp":1790030473680,"version":"4.0.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T00:00:00Z","timestamp":1601683200000},"content-version":"am","delay-in-days":368,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy Hypertension"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.preghy.2019.09.006","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T11:58:06Z","timestamp":1570103886000},"page":"112-116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Combined effects of increasing maternal age and nulliparity on hypertensive disorders of pregnancy and small for gestational age"],"prefix":"10.1016","volume":"18","author":[{"given":"Thomas","family":"Desplanches","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Bouit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Cottenet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Szczepanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Quantin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Fauque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Sagot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.preghy.2019.09.006_b0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056583","article-title":"Advanced maternal age and adverse pregnancy outcome: evidence from a large contemporary cohort","volume":"8","author":"Kenny","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0010","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/AOG.0000000000001197","article-title":"Trends in severe maternal morbidity after assisted reproductive technology in the United States, 2008\u20132012","volume":"127","author":"Martin","year":"2016","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.preghy.2019.09.006_b0015","unstructured":"The European Perinatal Health Report 2015, Europeristat report https:\/\/www.europeristat.com\/. (accessed February 2019)."},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0020","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.midw.2010.07.006","article-title":"Advanced maternal age and adverse perinatal outcome: a review of the evidence","volume":"27","author":"Carolan","year":"2011","journal-title":"Midwifery"},{"issue":"19","key":"10.1016\/j.preghy.2019.09.006_b0025","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1056\/NEJMp048087","article-title":"Advanced maternal age\u2013how old is too old?","volume":"351","author":"Heffner","year":"2004","journal-title":"N Engl. J. Med."},{"issue":"3","key":"10.1016\/j.preghy.2019.09.006_b0030","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1523-536X.2010.00409.x","article-title":"Advanced maternal age and the risk of cesarean birth: a systematic review","volume":"37","author":"Bayrampour","year":"2010","journal-title":"Birth"},{"issue":"10","key":"10.1016\/j.preghy.2019.09.006_b0035","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1056\/NEJM199003083221004","article-title":"Delayed childbearing and the outcome of pregnancy","volume":"322","author":"Berkowitz","year":"1990","journal-title":"N Engl. J. Med."},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0040","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/0029-7844(96)00045-2","article-title":"Pregnancy outcome at age 40 and older","volume":"87","author":"Bianco","year":"1996","journal-title":"Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.preghy.2019.09.006_b0045","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.ajog.2006.10.862","article-title":"Pregnancy at or beyond age 40 years is associated with an increased risk of fetal death and other adverse outcomes","volume":"196","author":"Hoffman","year":"2007","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"7491","key":"10.1016\/j.preghy.2019.09.006_b0050","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1136\/bmj.38380.674340.E0","article-title":"Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies","volume":"330","author":"Duckitt","year":"2005","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.preghy.2019.09.006_b0055","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S1701-2163(15)30533-8","article-title":"Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: executive summary","volume":"36","author":"Magee","year":"2014","journal-title":"J. Obstet. Gynaecol. Can."},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0060","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.preghy.2013.10.001","article-title":"Effect of age, parity, and race on the incidence of pregnancy associated hypertension and eclampsia in the United States","volume":"4","author":"Gold","year":"2014","journal-title":"Pregnancy Hypertens."},{"issue":"7","key":"10.1016\/j.preghy.2019.09.006_b0065","doi-asserted-by":"crossref","first-page":"862","DOI":"10.3109\/00016349.2010.486827","article-title":"Knowledge Synthesis Group on Determinants of LBWPTb. Parity and low birth weight and preterm birth: a systematic review and meta-analyses","volume":"89","author":"Shah","year":"2010","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0070","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.bpobgyn.2009.06.003","article-title":"Risk factors for small for gestational age infants","volume":"23","author":"McCowan","year":"2009","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"issue":"12S","key":"10.1016\/j.preghy.2019.09.006_b0075","first-page":"S8","article-title":"Epidemiology of maternal mortality in France, 2010\u20132012","volume":"45","author":"Deneux-Tharaux","year":"2017","journal-title":"Gynecol. Obstet. Fertil. Senol."},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0080","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.atherosclerosis.2015.01.027","article-title":"Sex differences in cardiovascular risk factors and disease prevention","volume":"241","author":"Appelman","year":"2015","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0085","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.bpobgyn.2009.06.005","article-title":"Neonatal management and long-term sequelae","volume":"23","author":"Halliday","year":"2009","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"issue":"27","key":"10.1016\/j.preghy.2019.09.006_b0090","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000000210","article-title":"The incidence rate, high-risk factors, and short- and long-term adverse outcomes of fetal growth restriction: a report from Mainland China","volume":"93","author":"Liu","year":"2014","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.preghy.2019.09.006_b0095","unstructured":"Volant S. A first child at age 28.5 in 2015: 4.5 years later than in 1974. https:\/\/www.insee.fr\/en\/statistiques\/2856712. (accessed February 2019)."},{"issue":"2","key":"10.1016\/j.preghy.2019.09.006_b0100","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ejogrb.2012.02.021","article-title":"Accuracy of blood transfusion in postpartum hemorrhage to assess maternal morbidity","volume":"162","author":"Sagot","year":"2012","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"3","key":"10.1016\/j.preghy.2019.09.006_b0105","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1093\/humrep\/der443","article-title":"Similarly increased congenital anomaly rates after intrauterine insemination and IVF technologies: a retrospective cohort study","volume":"27","author":"Sagot","year":"2012","journal-title":"Hum. Reprod."},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0110","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S1386-5056(98)00019-7","article-title":"How to ensure data security of an epidemiological follow-up: quality assessment of an anonymous record linkage procedure","volume":"49","author":"Quantin","year":"1998","journal-title":"Int. J. Med. Inform."},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0115","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1542\/peds.2005-2149","article-title":"Improving perinatal regionalization by predicting neonatal intensive care requirements of preterm infants: an EPIPAGE-based cohort study","volume":"118","author":"Vieux","year":"2006","journal-title":"Pediatrics"},{"issue":"11","key":"10.1016\/j.preghy.2019.09.006_b0120","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1093\/humrep\/15.11.2433","article-title":"The risks associated with pregnancy in women aged 35 years or older","volume":"15","author":"Jolly","year":"2000","journal-title":"Hum. Reprod."},{"issue":"2","key":"10.1016\/j.preghy.2019.09.006_b0125","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/ije\/dyl284","article-title":"Teenage pregnancy and adverse birth outcomes: a large population based retrospective cohort study","volume":"36","author":"Chen","year":"2007","journal-title":"Int. J. Epidemiol."},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0130","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1093\/humrep\/dem043","article-title":"Teenage pregnancy and congenital anomalies: which system is vulnerable?","volume":"22","author":"Chen","year":"2007","journal-title":"Hum. Reprod."},{"issue":"12","key":"10.1016\/j.preghy.2019.09.006_b0135","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1111\/1471-0528.12282","article-title":"Comparison of the ability of alternative birthweight and fetal weight standards to identify preterm newborns at increased risk of perinatal death","volume":"120","author":"Ferdynus","year":"2013","journal-title":"BJOG"},{"issue":"4","key":"10.1016\/j.preghy.2019.09.006_b0140","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/sim.4067","article-title":"Multiple imputation using chained equations: Issues and guidance for practice","volume":"30","author":"White","year":"2011","journal-title":"Stat. Med."},{"issue":"4","key":"10.1016\/j.preghy.2019.09.006_b0145","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/sim.4780100410","article-title":"Multiple imputation in health-care databases: an overview and some applications","volume":"10","author":"Rubin","year":"1991","journal-title":"Stat. Med."},{"issue":"4","key":"10.1016\/j.preghy.2019.09.006_b0150","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jgyn.2012.04.014","article-title":"National coordination group of the national perinatal S. Trends in perinatal health in France from 1995 to 2010. Results from the French National Perinatal Surveys","volume":"41","author":"Blondel","year":"2012","journal-title":"J. Gynecol. Obstet. Biol. Reprod. (Paris)"},{"issue":"3","key":"10.1016\/j.preghy.2019.09.006_b0155","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ijgo.2008.05.004","article-title":"Effect of parity and advanced maternal age on obstetric outcome","volume":"102","author":"Chan","year":"2008","journal-title":"Int. J. Gynaecol. Obstet."},{"issue":"4","key":"10.1016\/j.preghy.2019.09.006_b0160","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00404-014-3469-0","article-title":"The effects of maternal age and parity on maternal and neonatal outcome","volume":"291","author":"Schimmel","year":"2015","journal-title":"Arch. Gynecol. Obstet."},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0165","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00404-010-1587-x","article-title":"The impact of advanced maternal age and parity on obstetric and perinatal outcomes in singleton gestations","volume":"284","author":"Wang","year":"2011","journal-title":"Arch. Gynecol. Obstet."},{"issue":"10","key":"10.1016\/j.preghy.2019.09.006_b0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0164462","article-title":"Risk of adverse obstetric and neonatal outcomes by maternal age: quantifying individual and population level risk using routine UK maternity data","volume":"11","author":"Oakley","year":"2016","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.preghy.2019.09.006_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2016.06.021","article-title":"Effect of maternal age on maternal and neonatal outcomes after assisted reproductive technology","volume":"106","author":"Wennberg","year":"2016","journal-title":"Fertil. Steril."},{"issue":"8","key":"10.1016\/j.preghy.2019.09.006_b0180","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1111\/1471-0528.14368","article-title":"Advanced maternal age increases the risk of very preterm birth, irrespective of parity: a population-based register study","volume":"124","author":"Waldenstrom","year":"2017","journal-title":"BJOG"},{"issue":"1","key":"10.1016\/j.preghy.2019.09.006_b0185","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1186\/s12884-018-1984-x","article-title":"The effect of advanced maternal age on perinatal outcomes in nulliparous singleton pregnancies","volume":"18","author":"Kahveci","year":"2018","journal-title":"BMC Pregnancy Childbirth."},{"issue":"31","key":"10.1016\/j.preghy.2019.09.006_b0190","first-page":"41","article-title":"The French public health information system","volume":"28","author":"Goldberg","year":"2012","journal-title":"J. Int. Assoc. Off. Stat."},{"issue":"6","key":"10.1016\/j.preghy.2019.09.006_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2010.01.012","article-title":"Placental vascular lesion differences in pregnancy-induced hypertension and normotensive fetal growth restriction","volume":"202","author":"Kovo","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"Suppl 3","key":"10.1016\/j.preghy.2019.09.006_b0200","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.1016\/S0049-3848(11)70026-3","article-title":"Placental pathology in pregnancy complications","volume":"127","author":"Huppertz","year":"2011","journal-title":"Thromb. Res."}],"container-title":["Pregnancy Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778919304301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778919304301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:51:51Z","timestamp":1761897111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210778919304301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":40,"alternative-id":["S2210778919304301"],"URL":"https:\/\/doi.org\/10.1016\/j.preghy.2019.09.006","relation":{},"ISSN":["2210-7789"],"issn-type":[{"value":"2210-7789","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combined effects of increasing maternal age and nulliparity on hypertensive disorders of pregnancy and small for gestational age","name":"articletitle","label":"Article Title"},{"value":"Pregnancy Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preghy.2019.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}