{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:04:54Z","timestamp":1787321094860,"version":"build-2736575974"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"vor","delay-in-days":127,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004421","name":"World Bank Group","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004421","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005036","name":"Universitetet i Bergen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005036","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005247","name":"University of British Columbia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy Hypertension"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.preghy.2020.11.012","type":"journal-article","created":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T13:24:01Z","timestamp":1607001841000},"page":"91-96","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study"],"prefix":"10.1016","volume":"23","author":[{"given":"G Justus","family":"Hofmeyr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Seuc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Pilar","family":"Betr\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Cormick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandisa","family":"Singata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Fawcus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simpiwe","family":"Mose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlyn","family":"Frank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Beliz\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura A.","family":"Magee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"von Dadelszen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.preghy.2020.11.012_b0005","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001059.pub5","article-title":"Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems","author":"Hofmeyr","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"issue":"5","key":"10.1016\/j.preghy.2020.11.012_b0010","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.3390\/nu11051112","article-title":"Mechanisms involved in the relationship between low calcium intake and high blood pressure","volume":"11","author":"Villa-Etchegoyen","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.preghy.2020.11.012_b0015","first-page":"163","article-title":"Molecular mechanisms triggered by low-calcium diets","volume":"22","author":"Centeno","year":"2009","journal-title":"NutrResRev"},{"issue":"1 Pt 1","key":"10.1016\/j.preghy.2020.11.012_b0020","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0895-7061(98)00224-6","article-title":"The influence of dietary and nondietary calcium supplementation on blood pressure: an updated metaanalysis of randomized controlled trials","volume":"12","author":"Griffith","year":"1999","journal-title":"Am. J. Hypertens."},{"issue":"7","key":"10.1016\/j.preghy.2020.11.012_b0025","doi-asserted-by":"crossref","first-page":"3824","DOI":"10.1210\/jc.2004-2205","article-title":"Effects of calcium supplementation on body weight and blood pressure in normal older women: a randomized controlled trial","volume":"90","author":"Reid","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"9","key":"10.1016\/j.preghy.2020.11.012_b0030","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1001\/jama.1983.03330330039033","article-title":"Reduction of blood pressure with calcium supplementation in young adults","volume":"249","author":"Belizan","year":"1983","journal-title":"JAMA"},{"key":"10.1016\/j.preghy.2020.11.012_b0035","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD010037.pub2","article-title":"Calcium supplementation for prevention of primary hypertension","author":"Cormick","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.preghy.2020.11.012_b0040","article-title":"Calcium supplementation for the management of primary hypertension in adults","author":"Dickinson","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.preghy.2020.11.012_b0045","unstructured":"Global Burden of Disease (GBD): Institute of Health Metrics; 2020 [Available from: http:\/\/www.healthdata.org\/gbd."},{"issue":"4","key":"10.1016\/j.preghy.2020.11.012_b0050","doi-asserted-by":"crossref","first-page":"193","DOI":"10.5830\/CVJA-2015-065","article-title":"Why is control of hypertension in sub-Saharan Africa poor?","volume":"26","author":"Seedat","year":"2015","journal-title":"Cardiovasc. J. Afr."},{"key":"10.1016\/j.preghy.2020.11.012_b0055","doi-asserted-by":"crossref","DOI":"10.1002\/uog.23189","article-title":"Cardiovascular events following pregnancies complicated by preeclampsia with emphasis on the comparison between early and late onset forms: a systematic review and meta-analysis","author":"Dall'Asta","year":"2020","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"10169","key":"10.1016\/j.preghy.2020.11.012_b0060","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0140-6736(18)31818-X","article-title":"Prepregnancy and early pregnancy calcium supplementation among women at high risk of pre-eclampsia: a multicentre, double-blind, randomised, placebo-controlled trial","volume":"393","author":"Hofmeyr","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.preghy.2020.11.012_b0065","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1186\/s13063-017-2220-0","article-title":"Participant recruitment and retention in longitudinal preconception randomized trials: lessons learnt from the Calcium And Pre-eclampsia (CAP) trial","volume":"18","author":"Lawrie","year":"2017","journal-title":"Trials."},{"issue":"4","key":"10.1016\/j.preghy.2020.11.012_b0070","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.preghy.2015.04.001","article-title":"The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: An exploratory, randomized placebo controlled study","volume":"5","author":"Hofmeyr","year":"2015","journal-title":"Pregnancy Hypertens."},{"key":"10.1016\/j.preghy.2020.11.012_b0075","article-title":"Impact of water fortification with calcium on calcium intake in different countries: a simulation study","volume":"1\u201314","author":"Cormick","year":"2020","journal-title":"Public Health Nutr."},{"issue":"4","key":"10.1016\/j.preghy.2020.11.012_b0080","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/1471-0528.15512","article-title":"Global inequities in dietary calcium intake during pregnancy: a systematic review and meta-analysis","volume":"126","author":"Cormick","year":"2019","journal-title":"BJOG"},{"issue":"1","key":"10.1016\/j.preghy.2020.11.012_b0085","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/s12884-018-1885-z","article-title":"Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe?","volume":"18","author":"Cormick","year":"2018","journal-title":"BMC Preg. Childbirth"},{"key":"10.1016\/j.preghy.2020.11.012_b0090","doi-asserted-by":"crossref","first-page":"10974","DOI":"10.1038\/srep10974","article-title":"Dietary calcium and zinc deficiency risks are decreasing but remain prevalent","volume":"5","author":"Kumssa","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preghy.2020.11.012_b0095","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1186\/1756-0500-7-920","article-title":"Gaps between calcium recommendations to prevent pre-eclampsia and current intakes in one hospital in Argentina","volume":"7","author":"Cormick","year":"2014","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.preghy.2020.11.012_b0100","series-title":"Calcium Supplementation in pregnant Women","author":"Guideline","year":"2013"},{"key":"10.1016\/j.preghy.2020.11.012_b0105","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/nu11071606","article-title":"Calcium intake and health","volume":"11","author":"Cormick","year":"2019","journal-title":"Nutrients"},{"issue":"8","key":"10.1016\/j.preghy.2020.11.012_b0110","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0895-7061(02)02964-3","article-title":"The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials","volume":"15","author":"Jee","year":"2002","journal-title":"Am. J. Hypertens."},{"issue":"6","key":"10.1016\/j.preghy.2020.11.012_b0115","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/jch.13010","article-title":"Calcium supplementation and cardiovascular risk: A rising concern","volume":"19","author":"Tankeu","year":"2017","journal-title":"J Clin Hypertens (Greenwich)."},{"issue":"1","key":"10.1016\/j.preghy.2020.11.012_b0120","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/jbmr.176","article-title":"Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up","volume":"26","author":"Lewis","year":"2011","journal-title":"J. Bone Miner. Res."},{"issue":"1","key":"10.1016\/j.preghy.2020.11.012_b0125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/jbmr.2311","article-title":"The effects of calcium supplementation on verified coronary heart disease hospitalization and death in postmenopausal women: a collaborative meta-analysis of randomized controlled trials","volume":"30","author":"Lewis","year":"2015","journal-title":"J. Bone Miner. Res."},{"issue":"3","key":"10.1016\/j.preghy.2020.11.012_b0130","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1002\/jbmr.1484","article-title":"Adverse events from calcium supplementation: relationship to errors in myocardial infarction self-reporting in randomized controlled trials of calcium supplementation","volume":"27","author":"Lewis","year":"2012","journal-title":"J. Bone Miner. Res."},{"issue":"5","key":"10.1016\/j.preghy.2020.11.012_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2017.02.015","article-title":"Effect of early-onset preeclampsia on cardiovascular risk in the fifth decade of life","volume":"216","author":"Bokslag","year":"2017","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"13","key":"10.1016\/j.preghy.2020.11.012_b0140","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1111\/1471-0528.15394","article-title":"Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis","volume":"125","author":"Brouwers","year":"2018","journal-title":"BJOG"},{"issue":"4","key":"10.1016\/j.preghy.2020.11.012_b0145","doi-asserted-by":"crossref","DOI":"10.3390\/nu12041022","article-title":"Regulatory and policy-related aspects of calcium fortification of foods. Implications for implementing national strategies of calcium fortification","volume":"12","author":"Cormick","year":"2020","journal-title":"Nutrients"},{"issue":"9349","key":"10.1016\/j.preghy.2020.11.012_b0150","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/S0140-6736(02)11911-8","article-title":"Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies","volume":"360","author":"Lewington","year":"2002","journal-title":"Lancet"},{"issue":"15","key":"10.1016\/j.preghy.2020.11.012_b0155","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1001\/jama.288.15.1882","article-title":"Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program","volume":"288","author":"Whelton","year":"2002","journal-title":"JAMA"},{"issue":"3 Suppl.","key":"10.1016\/j.preghy.2020.11.012_b0160","first-page":"I95","article-title":"Blood pressure and high blood pressure. Aspects of risk","volume":"18","author":"Stamler","year":"1991","journal-title":"Hypertension"}],"container-title":["Pregnancy Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778920301574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778920301574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:53:01Z","timestamp":1761897181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210778920301574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":32,"alternative-id":["S2210778920301574"],"URL":"https:\/\/doi.org\/10.1016\/j.preghy.2020.11.012","relation":{},"ISSN":["2210-7789"],"issn-type":[{"value":"2210-7789","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study","name":"articletitle","label":"Article Title"},{"value":"Pregnancy Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preghy.2020.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V. on behalf of International Society for the Study of Hypertension in Pregnancy.","name":"copyright","label":"Copyright"}]}}