{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T10:10:22Z","timestamp":1737972622482,"version":"3.33.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy Hypertension"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.preghy.2024.101115","type":"journal-article","created":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T10:29:24Z","timestamp":1712831364000},"page":"101115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Placental and serum levels of human \u03b1-Klotho in preeclampsia & intra-uterine growth retardation: A potential sensitive biomarker?"],"prefix":"10.1016","volume":"36","author":[{"given":"Shehada","family":"Sabren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadmor","family":"Hagar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nardeen","family":"Khateeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farber","family":"Evgeny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis-Nakhle","family":"Yara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youri","family":"Perlitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nakhoul","family":"Farid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.preghy.2024.101115_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/jcm8101625","article-title":"Preeclampsia: Risk Factors, Diagnosis, Management, and the Cardiovascular Impact on the Offspring","volume":"8","author":"Fox","year":"2019","journal-title":"J. Clin. Med."},{"issue":"9","key":"10.1016\/j.preghy.2024.101115_b0010","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1055\/s-0037-1604471","article-title":"Preeclampsia","volume":"39","author":"Ramos","year":"2017","journal-title":"Rev. BrasGinecol. Obstet."},{"issue":"2","key":"10.1016\/j.preghy.2024.101115_b0015","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00424-009-0722-7","article-title":"Klotho","volume":"459","author":"Kuro-o","year":"2010","journal-title":"Pflugers Arch."},{"issue":"6655","key":"10.1016\/j.preghy.2024.101115_b0020","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/36285","article-title":"Mutation of the mouse klotho gene leads to a syndrome resembling ageing","volume":"390","author":"Kuro-o","year":"1997","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.preghy.2024.101115_b0025","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1210\/er.2013-1079","article-title":"Molecular basis of Klotho: from gene to function in aging","volume":"36","author":"Xu","year":"2015","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.preghy.2024.101115_b0030","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3389\/fendo.2017.00323","article-title":"New insights into the mechanism of action of soluble klotho","volume":"8","author":"Dalton","year":"2017","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"12","key":"10.1016\/j.preghy.2024.101115_b0035","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1136\/jcp.2008.055236","article-title":"The placenta in pre-eclampsia and intrauterine growth restricton","volume":"61","author":"Roberts","year":"2008","journal-title":"J. Clin. Pathol."},{"issue":"7","key":"10.1016\/j.preghy.2024.101115_b0040","doi-asserted-by":"crossref","first-page":"e13417","DOI":"10.1111\/acel.13417","article-title":"Advanced maternal age causes premature placental senescence and malformation via dysregulated alpha-Klotho expression in trophoblasts","volume":"20","author":"Chen","year":"2021","journal-title":"Aging Cell"},{"key":"10.1016\/j.preghy.2024.101115_b0045","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.preghy.2022.08.008","article-title":"Evaluation of Klotho gene expression and NGAL levels following acute kidney injury during pregnancy hypertensive disorders","volume":"30","author":"Jiang","year":"2022","journal-title":"Pregnancy Hypertens."},{"issue":"5","key":"10.1016\/j.preghy.2024.101115_b0050","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3109\/14767058.2013.818652","article-title":"The anti-aging factor alpha-klotho during human pregnancy and its expression in pregnancies complicated by small-for-gestational-age neonates and\/or preeclampsia","volume":"27","author":"Miranda","year":"2014","journal-title":"J. Matern. Fetal. Neonatal. Med."},{"issue":"6","key":"10.1016\/j.preghy.2024.101115_b0055","doi-asserted-by":"crossref","first-page":"E943","DOI":"10.1210\/jc.2010-2357","article-title":"Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood","volume":"96","author":"Ohata","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.preghy.2024.101115_b0060","first-page":"1998","article-title":"Clinic significance of markedly decreased alpha-klothoin women with preeclampsia","volume":"8","author":"Fan","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.preghy.2024.101115_b0065","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.placenta.2019.08.084","article-title":"Placental and serum levels of human Klotho in severe preeclampsia: A potential sensitive biomarker","volume":"85","author":"Cilingir","year":"2019","journal-title":"Placenta"},{"issue":"Suppl 1","key":"10.1016\/j.preghy.2024.101115_b0070","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1111\/nure.12055","article-title":"Epidemiology of preeclampsia: impact of obesity","volume":"71","author":"Jeyabalan","year":"2013","journal-title":"Nutr. Rev."},{"issue":"19","key":"10.1016\/j.preghy.2024.101115_b0075","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1056\/NEJMra2109523","article-title":"Preeclampsia","volume":"386","author":"Magee","year":"2022","journal-title":"N Engl. J. Med."},{"issue":"2","key":"10.1016\/j.preghy.2024.101115_b0080","first-page":"65","article-title":"Predictive factors for intrauterine growth restriction","volume":"7","author":"Albu","year":"2014","journal-title":"J. Med. Life"},{"issue":"24","key":"10.1016\/j.preghy.2024.101115_b0085","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.3109\/14767058.2016.1152249","article-title":"Intrauterine growth restriction - part 1","volume":"29","author":"Sharma","year":"2016","journal-title":"J Matern. Fetal Neonatal. Med."},{"issue":"7","key":"10.1016\/j.preghy.2024.101115_b0090","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1111\/j.1471-0528.2012.03313.x","article-title":"Maternal and pathological pregnancy characteristics in customised birthweight centiles and identification of at-risk small-for-gestational-age infants: a retrospective cohort study","volume":"119","author":"Anderson","year":"2012","journal-title":"BJOG"},{"key":"10.1016\/j.preghy.2024.101115_b0095","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f108","article-title":"Maternal and fetal risk factors for stillbirth: population based study","volume":"346","author":"Gardosi","year":"2013","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.preghy.2024.101115_b0100","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/uog.1806","article-title":"Does antenatal identification of small-for-gestational age fetuses significantly improve their outcome?","volume":"25","author":"Lindqvist","year":"2005","journal-title":"UltrasoundObstet Gynecol"},{"issue":"2","key":"10.1016\/j.preghy.2024.101115_b0105","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/uog.11204","article-title":"Fetal growth: a review of terms, concepts and issues relevant to obstetrics","volume":"41","author":"Mayer","year":"2013","journal-title":"UltrasoundObstet Gynecol"},{"issue":"5","key":"10.1016\/j.preghy.2024.101115_b0110","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1172\/JCI17189","article-title":"Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia","volume":"111","author":"Maynard","year":"2003","journal-title":"J. Clin. Invest."}],"container-title":["Pregnancy Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778924001405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778924001405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T08:58:44Z","timestamp":1737968324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210778924001405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":22,"alternative-id":["S2210778924001405"],"URL":"https:\/\/doi.org\/10.1016\/j.preghy.2024.101115","relation":{},"ISSN":["2210-7789"],"issn-type":[{"type":"print","value":"2210-7789"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Placental and serum levels of human \u03b1-Klotho in preeclampsia & intra-uterine growth retardation: A potential sensitive biomarker?","name":"articletitle","label":"Article Title"},{"value":"Pregnancy Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preghy.2024.101115","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101115"}}