{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:27:04Z","timestamp":1788805624245,"version":"build-2803163510"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"am","delay-in-days":318,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015691","name":"National Institute of Allergy and Infectious Diseases Division of Microbiology and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI141501"],"award-info":[{"award-number":["1R01AI141501"]}],"id":[{"id":"10.13039\/100015691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy Hypertension"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.preghy.2024.101165","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T15:42:05Z","timestamp":1729006925000},"page":"101165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Maternal characteristics impact the relationship between fetal sex and superimposed preeclampsia"],"prefix":"10.1016","volume":"38","author":[{"given":"Akaninyene I.","family":"Noah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camillia R.","family":"Comeaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley V.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Perez-Patron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandie","family":"DePaoli Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0005","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.earlhumdev.2003.10.006","article-title":"Offspring sex and pregnancy outcome by length of gestation","volume":"76","author":"Vatten","year":"2004","journal-title":"Early Hum. Dev."},{"issue":"13","key":"10.1016\/j.preghy.2024.101165_b0010","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10133000","article-title":"Sex differences are here to stay: relevance to prenatal care","volume":"10","author":"Inkster","year":"2021","journal-title":"J. Clin. Med."},{"issue":"Suppl","key":"10.1016\/j.preghy.2024.101165_b0015","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.placenta.2009.11.010","article-title":"Review: sex and the human placenta: mediating differential strategies of fetal growth and survival","volume":"31","author":"Clifton","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.preghy.2024.101165_b0020","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.placenta.2016.12.008","article-title":"Review: sexual dimorphism in the formation, function and adaptation of the placenta","volume":"54","author":"Kalisch-Smith","year":"2017","journal-title":"Placenta"},{"issue":"12","key":"10.1016\/j.preghy.2024.101165_b0025","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.placenta.2013.09.015","article-title":"Evidence of sexual dimorphism in the placental function with severe preeclampsia","volume":"34","author":"Muralimanoharan","year":"2013","journal-title":"Placenta"},{"key":"10.1016\/j.preghy.2024.101165_b0030","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.placenta.2017.02.004","article-title":"Sexual dimorphism in the effect of maternal obesity on antioxidant defense mechanisms in the human placenta","volume":"51","author":"Evans","year":"2017","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0035","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s10020-023-00688-5","article-title":"Regulation of sexually dimorphic placental adaptation in LPS exposure-induced intrauterine growth restriction","volume":"29","author":"Jeong","year":"2023","journal-title":"Mol. Med."},{"issue":"5","key":"10.1016\/j.preghy.2024.101165_b0040","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1161\/HYPERTENSIONAHA.111.00250","article-title":"Redefining preeclampsia using placenta-derived biomarkers","volume":"61","author":"Staff","year":"2013","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0045","doi-asserted-by":"crossref","DOI":"10.1186\/s13293-020-00299-3","article-title":"Fetal sex and maternal pregnancy outcomes: a systematic review and meta-analysis","volume":"11","author":"Broere-Brown","year":"2020","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.preghy.2024.101165_b0050","unstructured":"O. Global Pregnancy Collaboration, S. Sckalekamp-Timmermans, L.R. Arends, E. Alsaker, L. Chappell, S. Hansson, N.K. Harsem, M. Jalmby, A. Jeyabalan, H. Laivuori, D.A. Lawlor, C. Macdonald-Wallis, P. Magnus, J. Myers, J. Olsen, L. Poston, C.W. Redman, A.C. Staff, P. Villa, J.M. Roberts, E.A. Steegers. Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis. Int. J. Epidemiol 46 (2) (2017, 632-642."},{"issue":"4","key":"10.1016\/j.preghy.2024.101165_b0055","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/1471-0528.14163","article-title":"Fetal sex and maternal risk of pre-eclampsia\/eclampsia: a systematic review and meta-analysis","volume":"124","author":"Jaskolka","year":"2017","journal-title":"BJOG"},{"issue":"21","key":"10.1016\/j.preghy.2024.101165_b0060","first-page":"1124","article-title":"Combined effect of fetal sex and advanced maternal age on pregnancy outcomes","volume":"20","author":"Weissmann-Brenner","year":"2015","journal-title":"Med. Sci. Monit."},{"issue":"11","key":"10.1016\/j.preghy.2024.101165_b0065","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/jp.2016.130","article-title":"Generation and validation of a universal perinatal database and biospecimen repository: PeriBank","volume":"36","author":"Antony","year":"2016","journal-title":"J. Perinatol."},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0070","doi-asserted-by":"crossref","first-page":"13904","DOI":"10.1038\/s41598-022-17989-0","volume":"12","author":"DePaoli Taylor","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preghy.2024.101165_b0075","unstructured":"O. American College of, S.f.M.-F.M. Gynecologists' Committee on Obstetric Practice, ACOG Practice Bulletin No. 202: Gestational hypertension and preeclampsia, Obstet. Gynecol. 133(1) (2019) 1."},{"issue":"2S","key":"10.1016\/j.preghy.2024.101165_b0080","doi-asserted-by":"crossref","first-page":"S835","DOI":"10.1016\/j.ajog.2021.11.1371","article-title":"The evolution of the diagnostic criteria of preeclampsia-eclampsia","volume":"226","author":"Tanner","year":"2022","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2S","key":"10.1016\/j.preghy.2024.101165_b0085","doi-asserted-by":"crossref","first-page":"S1182","DOI":"10.1016\/j.ajog.2020.11.029","article-title":"Chronic hypertension and superimposed preeclampsia: screening and diagnosis","volume":"226","author":"Kametas","year":"2022","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"10","key":"10.1016\/j.preghy.2024.101165_b0090","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1093\/aje\/kwg074","article-title":"Estimating the relative risk in cohort studies and clinical trials of common outcomes","volume":"157","author":"McNutt","year":"2003","journal-title":"Am. J. Epidemiol."},{"issue":"3","key":"10.1016\/j.preghy.2024.101165_b0095","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/aje\/kwx349","article-title":"Multiple Imputation for incomplete data in epidemiologic studies","volume":"187","author":"Harel","year":"2018","journal-title":"Am. J. Epidemiol."},{"issue":"6","key":"10.1016\/j.preghy.2024.101165_b0100","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/aje\/kwn411","article-title":"Estimation of the relative excess risk due to interaction and associated confidence bounds","volume":"169","author":"Richardson","year":"2009","journal-title":"Am. J. Epidemiol."},{"issue":"4","key":"10.1016\/j.preghy.2024.101165_b0105","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1007\/s43032-022-01106-7","article-title":"Evaluating the impact of fetal sex on gestational diabetes mellitus following interaction with maternal characteristics","volume":"30","author":"Hooks","year":"2023","journal-title":"Reprod. Sci."},{"issue":"5","key":"10.1016\/j.preghy.2024.101165_b0110","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1007\/s43032-022-00891-5","article-title":"Disparities in prenatal sexually transmitted infections among a diverse population of foreign-born and US-born women","volume":"29","author":"Noah","year":"2022","journal-title":"Reprod. Sci."},{"issue":"21","key":"10.1016\/j.preghy.2024.101165_b0115","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1001\/jama.294.21.2751","article-title":"Manifestations of chronic disease during pregnancy","volume":"294","author":"Kaaja","year":"2005","journal-title":"J. Am. Med. Assoc."},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0120","doi-asserted-by":"crossref","DOI":"10.1186\/s12884-020-03039-y","article-title":"Does sex matter? association of fetal sex and parental age with pregnancy outcomes in Taiwan: a cohort study","volume":"20","author":"Yu","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"issue":"Suppl_1","key":"10.1016\/j.preghy.2024.101165_b0125","doi-asserted-by":"crossref","first-page":"A069","DOI":"10.1161\/hyp.79.suppl_1.069","article-title":"Abstract 069: methylation of the androgen receptor in white adipose tissue contributes to female obesity and hypertension in BPH\/5, a model of superimposed preeclampsia","volume":"79","author":"Sones","year":"2022","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0130","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cell.2016.08.009","article-title":"Single-cell RNA-seq reveals lineage and X chromosome dynamics in human preimplantation embryos","volume":"167","author":"Petropoulos","year":"2016","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.preghy.2024.101165_b0135","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/aji.12075","article-title":"Minor histocompatibility antigens and the maternal immune response to the fetus during pregnancy","volume":"69","author":"Linscheid","year":"2013","journal-title":"Am. J. Reprod. Immunol."},{"issue":"12","key":"10.1016\/j.preghy.2024.101165_b0140","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22126386","article-title":"Let's Talk about placental sex, baby: understanding mechanisms that drive female- and male-specific fetal growth and developmental outcomes","volume":"22","author":"Meakin","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preghy.2024.101165_b0145","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bbi.2016.06.015","article-title":"Fetal sex is associated with maternal stimulated cytokine production, but not serum cytokine levels, in human pregnancy","volume":"60","author":"Mitchell","year":"2017","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.preghy.2024.101165_b0150","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/aji.12303","article-title":"Fetal sex-based differences in maternal hormones, angiogenic factors, and immune mediators during pregnancy and the postpartum period","volume":"73","author":"Enninga","year":"2015","journal-title":"Am. J. Reprod. Immunol."},{"issue":"6","key":"10.1016\/j.preghy.2024.101165_b0155","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.placenta.2014.03.014","article-title":"Fetal sex specific differences in human placentation: a prospective cohort study","volume":"35","author":"Brown","year":"2014","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.preghy.2024.101165_b0160","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/1933719114537713","article-title":"Mid-trimester maternal ADAM12 levels differ according to fetal gender in pregnancies complicated by preeclampsia","volume":"22","author":"Myers","year":"2015","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.preghy.2024.101165_b0165","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ejogrb.2016.09.004","article-title":"Standard curves of placental weight and fetal\/placental weight ratio in Japanese population: difference according to the delivery mode, fetal sex, or maternal parity","volume":"206","author":"Ogawa","year":"2016","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"14","key":"10.1016\/j.preghy.2024.101165_b0170","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1113\/jphysiol.2014.272856","article-title":"Mid- to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex-specific manner","volume":"592","author":"Cuffe","year":"2014","journal-title":"J. Physiol."},{"issue":"11","key":"10.1016\/j.preghy.2024.101165_b0175","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1210\/en.2012-1479","article-title":"Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression","volume":"153","author":"Cuffe","year":"2012","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0180","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1530\/jrf.0.0930125","article-title":"Glucose and glutamine metabolism in pre-attachment cattle embryos in relation to sex and stage of development","volume":"93","author":"Tiffin","year":"1991","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.preghy.2024.101165_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2020.155290","article-title":"Male fetal sex is associated with low maternal plasma anti-inflammatory cytokine profile in the first trimester of healthy pregnancies","volume":"136","author":"Ramiro-Cortijo","year":"2020","journal-title":"Cytokine"},{"issue":"6","key":"10.1016\/j.preghy.2024.101165_b0190","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0358-19.2019","article-title":"\u201cFemales Are Not Just 'Protected' Males\u201d: Sex-specific vulnerabilities in placenta and brain after prenatal immune disruption","volume":"6","author":"Braun","year":"2019","journal-title":"eNeuro"},{"issue":"11","key":"10.1016\/j.preghy.2024.101165_b0195","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1210\/en.2019-00493","article-title":"Toll-Like receptor-4 antagonist (+)-naloxone confers sexually dimorphic protection from inflammation-induced fetal programming in mice","volume":"160","author":"Chin","year":"2019","journal-title":"Endocrinology"},{"issue":"12","key":"10.1016\/j.preghy.2024.101165_b0200","doi-asserted-by":"crossref","first-page":"5557","DOI":"10.1073\/pnas.1000440107","article-title":"Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta","volume":"107","author":"Mao","year":"2010","journal-title":"PNAS"},{"issue":"6","key":"10.1016\/j.preghy.2024.101165_b0205","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18061171","article-title":"Ontogeny of sex-related differences in foetal developmental features, lipid availability and fatty acid composition","volume":"18","author":"Garcia-Contreras","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preghy.2024.101165_b0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2015.12.008","article-title":"Sex specific adaptations in placental biometry of overweight and obese women","volume":"38","author":"Mando","year":"2016","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.preghy.2024.101165_b0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/ppe.12417","article-title":"Trends in risk of pregnancy loss among US women, 1990\u20132011","volume":"32","author":"Rossen","year":"2018","journal-title":"Paediatr. Perinat. Epidemiol."}],"container-title":["Pregnancy Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778924001922?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778924001922?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T05:34:09Z","timestamp":1740807249000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210778924001922"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":43,"alternative-id":["S2210778924001922"],"URL":"https:\/\/doi.org\/10.1016\/j.preghy.2024.101165","relation":{},"ISSN":["2210-7789"],"issn-type":[{"value":"2210-7789","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal characteristics impact the relationship between fetal sex and superimposed preeclampsia","name":"articletitle","label":"Article Title"},{"value":"Pregnancy Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preghy.2024.101165","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101165"}}