{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T23:05:23Z","timestamp":1770678323802,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"am","delay-in-days":284,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pregnancy Hypertension"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.preghy.2025.101206","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T09:51:51Z","timestamp":1741773111000},"page":"101206","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Circulating follistatin-like 3 and its association with postpartum cardiovascular dysfunction and severe maternal morbidity"],"prefix":"10.1016","volume":"40","author":[{"given":"Junaid","family":"Nizamuddin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Dreixler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2669-5301","authenticated-orcid":false,"given":"Ana","family":"Palei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joey","family":"Granger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avery","family":"Tung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5828-7433","authenticated-orcid":false,"given":"Sarosh","family":"Rana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajid","family":"Shahul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.preghy.2025.101206_b0005","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1161\/CIRCULATIONAHA.117.031592","article-title":"Cardiovascular complications in pregnancy: it is time for action","volume":"137","author":"Graves","year":"2018","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.preghy.2025.101206_b0010","doi-asserted-by":"crossref","first-page":"e561","DOI":"10.1542\/neo.20-10-e561","article-title":"Maternal mortality in the United States: updates on trends, causes, and solutions","volume":"20","author":"Collier","year":"2019","journal-title":"NeoReviews"},{"issue":"3","key":"10.1016\/j.preghy.2025.101206_b0015","doi-asserted-by":"crossref","first-page":"379e1","DOI":"10.1016\/j.ajog.2015.05.008","article-title":"Pregnancy-related cardiovascular deaths in California: beyond peripartum cardiomyopathy","volume":"213","author":"Hameed","year":"2015","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.preghy.2025.101206_b0020","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0029-7844(96)00135-4","article-title":"Pregnancy-related mortality in the United States, 1987-1990","volume":"88","author":"Berg","year":"1996","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.preghy.2025.101206_b0025","doi-asserted-by":"crossref","unstructured":"D.L. Hoyert, Maternal mortality rates in the United States, 2022. NCHS Health E-Stats. 2024.","DOI":"10.15620\/cdc\/152992"},{"issue":"1","key":"10.1016\/j.preghy.2025.101206_b0030","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1161\/HYPERTENSIONAHA.118.10888","article-title":"Activin A and late postpartum cardiac dysfunction among women with hypertensive disorders of pregnancy","volume":"72","author":"Shahul","year":"2018","journal-title":"Hypertension."},{"issue":"6","key":"10.1016\/j.preghy.2025.101206_b0035","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1161\/HYPERTENSIONAHA.116.07252","article-title":"Circulating antiangiogenic factors and myocardial dysfunction in hypertensive disorders of pregnancy","volume":"67","author":"Shahul","year":"2016","journal-title":"Hypertension."},{"issue":"4","key":"10.1016\/j.preghy.2025.101206_b0040","doi-asserted-by":"crossref","DOI":"10.3390\/cells11040742","article-title":"Sustained elevated circulating Activin A impairs global longitudinal strain in pregnant rats: a potential mechanism for preeclampsia-related cardiac dysfunction","volume":"11","author":"Bakrania","year":"2022","journal-title":"Cells."},{"issue":"12","key":"10.1016\/j.preghy.2025.101206_b0045","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.015997","article-title":"Antepartum aspirin administration reduces Activin A and cardiac global longitudinal strain in preeclamptic women","volume":"9","author":"Naseem","year":"2020","journal-title":"J. Am. Heart Assoc."},{"issue":"5","key":"10.1016\/j.preghy.2025.101206_b0050","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.018526","article-title":"Long-term postpartum cardiac function and its association with preeclampsia","volume":"10","author":"deMartelly","year":"2021","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.preghy.2025.101206_b0055","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.preghy.2023.10.002","article-title":"Association of activin A and postpartum blood pressure in peripartum cardiomyopathy","volume":"34","author":"Koczo","year":"2023","journal-title":"Pregnancy Hypertens."},{"issue":"16","key":"10.1016\/j.preghy.2025.101206_b0060","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1161\/CIRCULATIONAHA.109.872200","article-title":"Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury","volume":"120","author":"Oshima","year":"2009","journal-title":"Circulation."},{"issue":"743","key":"10.1016\/j.preghy.2025.101206_b0065","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adi0077","article-title":"Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human","volume":"16","author":"Roh","year":"2024","journal-title":"Sci. Transl. Med."},{"issue":"3","key":"10.1016\/j.preghy.2025.101206_b0070","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.bbrc.2018.10.139","article-title":"Involvement of follistatin-like 3 in preeclampsia","volume":"506","author":"Xie","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.preghy.2025.101206_b0075","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1177\/1933719114529372","article-title":"Follistatin-like 3 across gestation in preeclampsia and uncomplicated pregnancies among lean and obese women","volume":"22","author":"Founds","year":"2015","journal-title":"Reprod. Sci."},{"issue":"7","key":"10.1016\/j.preghy.2025.101206_b0080","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1111\/j.1447-0756.2011.01823.x","article-title":"Alterations of maternal serum and placental follistatin-like 3 and myostatin in pre-eclampsia","volume":"38","author":"Guo","year":"2012","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"5","key":"10.1016\/j.preghy.2025.101206_b0085","first-page":"1122","article-title":"Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy","volume":"122","author":"Hypertension in Pregnancy","year":"2013","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.preghy.2025.101206_b0095","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2431-13-59","article-title":"A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants","volume":"13","author":"Fenton","year":"2013","journal-title":"BMC Pediatr."},{"issue":"1","key":"10.1016\/j.preghy.2025.101206_b0100","doi-asserted-by":"crossref","DOI":"10.1093\/gerona\/glad206","article-title":"Circulating growth differentiation factors 11 and 8, their antagonists follistatin and follistatin-like-3, and risk of heart failure in elders","volume":"79","author":"Kizer","year":"2024","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"issue":"482","key":"10.1016\/j.preghy.2025.101206_b0105","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aau8680","article-title":"Activin type II receptor signaling in cardiac aging and heart failure","volume":"11","author":"Roh","year":"2019","journal-title":"Sci. Transl. Med."},{"issue":"2","key":"10.1016\/j.preghy.2025.101206_b0110","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2174\/1568008043339901","article-title":"Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders","volume":"4","author":"Tsuchida","year":"2004","journal-title":"Curr. Drug Targets Immune Endocr. Metabol. Disord."},{"issue":"1","key":"10.1016\/j.preghy.2025.101206_b0115","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s12933-023-02024-x","article-title":"FSTL3 partially mediates the association of increased nonalcoholic fatty liver disease fibrosis risk with acute myocardial infarction in patients with type 2 diabetes mellitus","volume":"22","author":"Duan","year":"2023","journal-title":"Cardiovasc. Diabetol."},{"issue":"10","key":"10.1016\/j.preghy.2025.101206_b0120","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1093\/ndt\/gfw472","article-title":"FSTL3 is increased in renal dysfunction","volume":"32","author":"Kralisch","year":"2017","journal-title":"Nephrol. Dial Transplant."},{"key":"10.1016\/j.preghy.2025.101206_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103780","article-title":"Clinical tools and biomarkers to predict preeclampsia","volume":"75","author":"MacDonald","year":"2022","journal-title":"EBioMedicine."},{"issue":"8","key":"10.1016\/j.preghy.2025.101206_b0130","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1161\/CIRCULATIONAHA.118.036748","article-title":"Cardiovascular disease-related morbidity and mortality in women with a history of pregnancy complications","volume":"139","author":"Grandi","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.preghy.2025.101206_b0135","unstructured":"Prevention CfDCa. Four in 5 pregnancy-related deaths in the U.S. are preventable 2022 [cited 2024 January 29]. Available from: https:\/\/www.cdc.gov\/media\/releases\/2022\/p0919-pregnancy-related-deaths.html#:\u223c:text=More%20than%2080%25%20of%20pregnancy,identify%20recommendations%20to%20prevent%20future."}],"container-title":["Pregnancy Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778925000224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210778925000224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T15:28:54Z","timestamp":1749482934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2210778925000224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":26,"alternative-id":["S2210778925000224"],"URL":"https:\/\/doi.org\/10.1016\/j.preghy.2025.101206","relation":{},"ISSN":["2210-7789"],"issn-type":[{"value":"2210-7789","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circulating follistatin-like 3 and its association with postpartum cardiovascular dysfunction and severe maternal morbidity","name":"articletitle","label":"Article Title"},{"value":"Pregnancy Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preghy.2025.101206","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101206"}}