{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:39:52Z","timestamp":1793309992258,"version":"4.5.0"},"reference-count":255,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress in Retinal and Eye Research"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.preteyeres.2004.08.002","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T17:23:58Z","timestamp":1100280238000},"page":"275-306","source":"Crossref","is-referenced-by-count":495,"title":["Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration"],"prefix":"10.1016","volume":"24","author":[{"given":"Andreas","family":"Wenzel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Grimm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijana","family":"Samardzija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte E.","family":"Rem\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.preteyeres.2004.08.002_bib1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1128\/MMBR.65.3.463-479.2001","article-title":"Autophagy in yeast","volume":"65","author":"Abeliovich","year":"2001","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0968-0004(01)01844-8","article-title":"The mitochondrial apoptosome","volume":"26","author":"Adrain","year":"2001","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib3","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1097\/00001756-200109170-00039","article-title":"Lens epithelium-derived growth factor (LEDGF) delays photoreceptor degeneration in explants of rd\/rd mouse retina","volume":"12","author":"Ahuja","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib4","first-page":"273","article-title":"Adenovirally expressed basic fibroblast growth factor rescues photoreceptor cells in RCS rats","volume":"40","author":"Akimoto","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib5","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/sj.cdd.4401293","article-title":"L-DNase II activation by the 24kDa apoptotic protease (AP24) in TNFalpha-induced apoptosis","volume":"10","author":"Altairac","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1515\/BMT.2004.020","article-title":"The retina implant\u2014new approach to a visual prosthesis. A model for intracortical visual prosthesis research","volume":"49","author":"Alteheld","year":"2004","journal-title":"Biomed. Tech. (Berl)"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib7","doi-asserted-by":"crossref","DOI":"10.1038\/nm950","article-title":"An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice","author":"Ambati","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib8","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0002-9394(02)01624-0","article-title":"A role for local inflammation in the formation of drusen in the aging eye","volume":"134","author":"Anderson","year":"2002","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.bbamcr.2003.07.001","article-title":"There is more to life and death than mitochondria","volume":"1644","author":"Annis","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib10","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.1128\/MCB.20.11.3781-3794.2000","article-title":"Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid","volume":"20","author":"Barry","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib11","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0014-4835(03)00059-9","article-title":"Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats","volume":"76","author":"Beatrice","year":"2003","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib12","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1038\/sj.gt.3300733","article-title":"Adenovirus-mediated delivery of rhodopsin-promoted bcl-2 results in a delay in photoreceptor cell death in the rd\/rd mouse","volume":"5","author":"Bennett","year":"1998","journal-title":"Gene Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib13","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.ceb.2003.10.002","article-title":"Regulators of IAP function","volume":"15","author":"Bergmann","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib14","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0002-9394(14)70212-0","article-title":"Retinal photoreceptor dystrophies LI. Edward Jackson Memorial Lecture","volume":"119","author":"Bird","year":"1995","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/0470092645.ch7","article-title":"What should a clinician know to be prepared for the advent of treatment of retinal dystrophies?","volume":"255","author":"Bird","year":"2004","journal-title":"Novartis Found Symp."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib16","first-page":"144","article-title":"Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice","volume":"9","author":"Bode","year":"2003","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib17","doi-asserted-by":"crossref","first-page":"14619","DOI":"10.1073\/pnas.242607899","article-title":"New insights and new approaches toward the study of age-related macular degeneration","volume":"99","author":"Bok","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib18","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1006\/exer.2002.1176","article-title":"Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds\/peripherin mutation","volume":"74","author":"Bok","year":"2002","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib19","doi-asserted-by":"crossref","unstructured":"Brouckaert, G., Kalai, M., Krysko, D.V., Saelens, X., Vercammen, D., Ndlovu, M., Haegeman, G., D\u2019Herde, K., Vandenabeele, P., 2004. Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production. Mol. Biol. Cell 15, 1089\u20131100.","DOI":"10.1091\/mbc.E03-09-0668"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.cellbio.15.1.269","article-title":"Biochemical pathways of caspase activation during apoptosis","volume":"15","author":"Budihardjo","year":"1999","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.cdd.4400852","article-title":"The autophagosomal\u2013lysosomal compartment in programmed cell death","volume":"8","author":"Bursch","year":"2001","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib22","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/0014-4835(91)90109-R","article-title":"Light damage in the rat retina","volume":"53","author":"Bush","year":"1991","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib23","first-page":"2697","article-title":"The effect of calcium channel blocker diltiazem on photoreceptor degeneration in the rhodopsin Pro213His rat","volume":"41","author":"Bush","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib24","first-page":"275","article-title":"A combination of CNTF and BDNF rescues rd photoreceptors but changes rod differentiation in the presence of RPE in retinal explants","volume":"42","author":"Caffe","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib25","doi-asserted-by":"crossref","first-page":"13913","DOI":"10.1073\/pnas.250478897","article-title":"Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha-subunit","volume":"97","author":"Calvert","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib26","first-page":"1646","article-title":"In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor","volume":"42","author":"Cao","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib27","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1167\/iovs.02-0368","article-title":"The effect of ischemic preconditioning on light-induced photoreceptor injury","volume":"44","author":"Casson","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib28","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1167\/iovs.03-0674","article-title":"The effect of retinal ganglion cell injury on light-induced photoreceptor degeneration","volume":"45","author":"Casson","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib29","doi-asserted-by":"crossref","first-page":"9282","DOI":"10.1523\/JNEUROSCI.18-22-09282.1998","article-title":"Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse","volume":"18","author":"Cayouette","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib30","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1006\/nbdi.1999.0263","article-title":"Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations","volume":"6","author":"Cayouette","year":"1999","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib31","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0042-6989(01)00212-7","article-title":"Animal models in research on retinal degenerations","volume":"42","author":"Chader","year":"2002","journal-title":"Vis. Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib32","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0896-6273(93)90072-Y","article-title":"Apoptosis","volume":"11","author":"Chang","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib33","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1023\/A:1006983304079","article-title":"Poly(ADP-ribose) polymerase","volume":"193","author":"Chatterjee","year":"1999","journal-title":"Mol. Cell Biochem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib34","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/jcb.10354","article-title":"Retinal neuroprotection by growth factors","volume":"88","author":"Chaum","year":"2003","journal-title":"J. Cell Biochem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib35","doi-asserted-by":"crossref","first-page":"7042","DOI":"10.1073\/pnas.93.14.7042","article-title":"bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations","volume":"93","author":"Chen","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib36","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1073\/pnas.96.7.3718","article-title":"Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase","volume":"96","author":"Chen","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib37","first-page":"2978","article-title":"Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness)","volume":"40","author":"Chen","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib38","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S0165-6147(00)01902-7","article-title":"Poly(ADP-ribose) polymerase","volume":"23","author":"Chiarugi","year":"2002","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib39","first-page":"1298","article-title":"Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration","volume":"40","author":"Chong","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib40","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/978-1-4615-0067-4_29","article-title":"Light-induced photoreceptor damage triggers DNA repair","volume":"533","author":"Cortina","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib41","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1385\/MN:28:2:111","article-title":"DNA repair in photoreceptor survival","volume":"28","author":"Cortina","year":"2003","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib42","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.222551899","article-title":"Drusen proteome analysis","author":"Crabb","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib43","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1038\/sj.onc.1207517","article-title":"Role of AIF in caspase-dependent and caspase-independent cell death","volume":"23","author":"Cregan","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib44","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s003350010081","article-title":"A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors","volume":"11","author":"Danciger","year":"2000","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib45","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1159\/000072047","article-title":"Gene therapy and animal models for retinal disease","volume":"37","author":"Dejneka","year":"2003","journal-title":"Dev. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib46","first-page":"184","article-title":"Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas","volume":"9","author":"Dentchev","year":"2003","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib47","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1038\/sj.onc.1207519","article-title":"Bcl-2 and calcium","volume":"23","author":"Distelhorst","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib48","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1038\/sj.cdd.4401105","article-title":"Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development","volume":"9","author":"Donovan","year":"2002","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib49","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbamcr.2003.08.011","article-title":"Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death","volume":"1644","author":"Donovan","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib50","doi-asserted-by":"crossref","first-page":"23000","DOI":"10.1074\/jbc.M005359200","article-title":"Light-induced photoreceptor apoptosis in vivo requires neuronal nitric-oxide synthase and guanylate cyclase activity and is caspase-3-independent","volume":"276","author":"Donovan","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib51","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.1523\/JNEUROSCI.23-13-05723.2003","article-title":"Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration","volume":"23","author":"Doonan","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib52","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/sj.cdd.4401159","article-title":"Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors","volume":"10","author":"Drexler","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib53","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0092-8674(00)00008-8","article-title":"Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition","volume":"102","author":"Du","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib54","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1001\/archopht.120.11.1435","article-title":"The role of apoptosis in age-related macular degeneration","volume":"120","author":"Dunaief","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib55","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1146\/annurev.biochem.68.1.383","article-title":"Mammalian caspases","volume":"68","author":"Earnshaw","year":"1999","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib56","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1159\/000268026","article-title":"Learning retina implants with epiretinal contacts","volume":"29","author":"Eckmiller","year":"1997","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib57","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S1535-6108(03)00306-4","article-title":"Defective autophagy leads to cancer","volume":"4","author":"Edinger","year":"2003","journal-title":"Cancer Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib58","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1038\/nrc1209","article-title":"AP-1","volume":"3","author":"Eferl","year":"2003","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib59","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1076\/ceyr.21.6.975.6984","article-title":"Photosensitized light-induced damage of IRBP (interphotoreceptor retinoid-binding protein)","volume":"21","author":"Fedorovich","year":"2000","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib60","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1084\/jem.190.6.861","article-title":"Macrophage and retinal pigment epithelium phagocytosis","volume":"190","author":"Finnemann","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib61","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1101\/gad.187900","article-title":"Fra-1 replaces c-Fos-dependent functions in mice","volume":"14","author":"Fleischmann","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib62","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1749-6632.1999.tb07837.x","article-title":"Calcium overload triggers rod photoreceptor apoptotic cell death in chemical-induced and inherited retinal degenerations","volume":"893","author":"Fox","year":"1999","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib63","first-page":"2724","article-title":"Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd\/rd mouse","volume":"40","author":"Frasson","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib64","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/13508","article-title":"Retinitis pigmentosa","volume":"5","author":"Frasson","year":"1999","journal-title":"Nat. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib65","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S1534-5807(04)00104-2","article-title":"To live or die by the sword","volume":"6","author":"Friedman","year":"2004","journal-title":"Dev. Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib66","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1001\/archopht.122.4.564","article-title":"Prevalence of age-related macular degeneration in the United States; The epidemiology of age-related macular degeneration","volume":"122","author":"Friedman","year":"2004","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib67","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/978-1-4419-8997-0_22","article-title":"Non-erythroid functions of erythropoietin","volume":"543","author":"Gassmann","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib68","doi-asserted-by":"crossref","unstructured":"Gollapalli, D.R., Rando, R.R., 2004. The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration. Proc. Natl. Acad. Sci. USA.","DOI":"10.1073\/pnas.0401936101"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib69","first-page":"3511","article-title":"DNA damage and repair in light-induced photoreceptor degeneration","volume":"43","author":"Gordon","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib70","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/00001756-199312000-00012","article-title":"Protection against light-induced retinal degeneration by an inhibitor of NO synthase","volume":"5","author":"Goureau","year":"1993","journal-title":"Neuroreport"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib71","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1038\/sj.onc.1207521","article-title":"Autophagy as a cell death and tumor suppressor mechanism","volume":"23","author":"Gozuacik","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib72","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.281.5381.1309","article-title":"Mitochondria and apoptosis","volume":"281","author":"Green","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib73","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1006\/mthe.2001.0289","article-title":"Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18","volume":"3","author":"Green","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib74","first-page":"3984","article-title":"Blue light's effects on rhodopsin","volume":"41","author":"Grimm","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib75","first-page":"252","article-title":"Gene expression in the mouse retina","volume":"6","author":"Grimm","year":"2000","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib76","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/75614","article-title":"Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration","volume":"25","author":"Grimm","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib77","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1038\/sj.cdd.4400871","article-title":"AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun","volume":"8","author":"Grimm","year":"2001","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib78","first-page":"497","article-title":"Rhodopsin-mediated blue-light damage to the rat retina","volume":"42","author":"Grimm","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib79","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/nm723","article-title":"HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration","volume":"8","author":"Grimm","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib80","doi-asserted-by":"crossref","first-page":"5651","DOI":"10.1523\/JNEUROSCI.1288-04.2004","article-title":"Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration","volume":"24","author":"Grimm","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib81","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1038\/sj.onc.1207512","article-title":"Lysosomes in cell death","volume":"23","author":"Guicciardi","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib82","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/nm0397-346","article-title":"The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo","volume":"3","author":"Hafezi","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib83","first-page":"2239","article-title":"Retinal degeneration in the rd mouse in the absence of c-fos","volume":"39","author":"Hafezi","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib84","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/sj.cdd.4400574","article-title":"Retinal photoreceptors are apoptosis-competent in the absence of JunD\/AP-1","volume":"6","author":"Hafezi","year":"1999","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib85","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1016\/S0042-6989(98)00313-7","article-title":"Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors","volume":"39","author":"Hafezi","year":"1999","journal-title":"Vis. Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib86","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S1350-9462(01)00010-6","article-title":"An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration","volume":"20","author":"Hageman","year":"2001","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib87","doi-asserted-by":"crossref","unstructured":"Hahn, P., Lindsten, T., Lyubarsky, A.L., Ying, G.S., Pugh, E.N., Thompson, C.B., Dunaief, J.L., 2004. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death Differ. 10.1038\/sj.cdd.4401486 [doi].","DOI":"10.1038\/sj.cdd.4401486"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib88","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1126\/science.1094359","article-title":"Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice","volume":"304","author":"Hanayama","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib89","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/ng984","article-title":"Evidence for two apoptotic pathways in light-induced retinal degeneration","volume":"32","author":"Hao","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib90","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0896-6273(00)81185-X","article-title":"Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration","volume":"26","author":"Harada","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib91","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1093\/hmg\/ddg289","article-title":"Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration","volume":"12","author":"Hayward","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib92","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1084\/jem.192.10.1391","article-title":"Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax","volume":"192","author":"Heibein","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib93","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1016\/S0002-9440(10)64321-0","article-title":"Clearance of apoptotic photoreceptors","volume":"162","author":"Hisatomi","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib94","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/exer.2000.0878","article-title":"Apoptotic photoreceptor death in the rhodopsin knockout mouse in the presence and absence of c-fos","volume":"71","author":"Hobson","year":"2000","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib95","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3109\/02713688808997242","article-title":"Morphology and time-course of defined photochemical lesions in the rabbit retina","volume":"7","author":"Hoppeler","year":"1988","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib96","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF02256547","article-title":"Intraocular gene transfer of ciliary neurotrophic factor rescues photoreceptor degeneration in RCS rats","volume":"11","author":"Huang","year":"2004","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib97","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0014-4835(02)92032-4","article-title":"Light damage susceptibility and RPE65 in rats","volume":"75","author":"Iseli","year":"2002","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib98","doi-asserted-by":"crossref","first-page":"8497","DOI":"10.1021\/bi0001776","article-title":"Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling","volume":"39","author":"Ishizawa","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib99","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S0006-2952(03)00487-8","article-title":"Potentiation of cellular antioxidant capacity by Bcl-2","volume":"66","author":"Jang","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib100","doi-asserted-by":"crossref","first-page":"R49","DOI":"10.1016\/S0960-9822(98)70032-6","article-title":"DNA repair","volume":"8","author":"Jeggo","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib101","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrm731","article-title":"Deadly encounter","volume":"3","author":"Jesenberger","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib102","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1038\/sj.leu.2401879","article-title":"Noncaspase proteases in apoptosis","volume":"14","author":"Johnson","year":"2000","journal-title":"Leukemia"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib103","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1006\/mcne.2001.1036","article-title":"Characterization of cell death pathways in murine retinal neurodegeneration implicates cytochrome c release, caspase activation, and bid cleavage","volume":"18","author":"Jomary","year":"2001","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib104","first-page":"2434","article-title":"Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration","volume":"37","author":"Joseph","year":"1996","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib105","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00176787","article-title":"Light-evoked arachidonic acid release in the retina","volume":"232","author":"Jung","year":"1994","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib106","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0014-4835(02)00334-2","article-title":"L-NAME protects against acute light damage in albino rats, but not against retinal degeneration in P23H and S334ter transgenic rats","volume":"76","author":"Kaldi","year":"2003","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib107","first-page":"3744","article-title":"Protective effect against ischemia and light damage of iris pigment epithelial cells transfected with the BDNF gene","volume":"43","author":"Kano","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib108","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1677\/joe.0.1690447","article-title":"AP-1\u2014glucocorticoid receptor crosstalk taken to a higher level","volume":"169","author":"Karin","year":"2001","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib109","first-page":"1802","article-title":"Caspaselike proteases activated in apoptotic photoreceptors of Royal College of Surgeons rats","volume":"40","author":"Katai","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib110","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0962-8924(01)02173-0","article-title":"Programmed cell death","volume":"11","author":"Kaufmann","year":"2001","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib111","first-page":"476","article-title":"Protective effect of halothane anesthesia on retinal light damage","volume":"42","author":"Keller","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib112","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s00347-003-0944-6","article-title":"Hereditary retinochoroidal dystrophies. Part 1","volume":"101","author":"Kellner","year":"2004","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib113","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/bjc.1972.33","article-title":"Apoptosis","volume":"26","author":"Kerr","year":"1972","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib114","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1562\/0031-8655(2000)071<0196:DOTART>2.0.CO;2","article-title":"Determinants of the apoptotic response to lysosomal photodamage","volume":"71","author":"Kessel","year":"2000","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib115","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1091\/mbc.10.5.1337","article-title":"Apg7p\/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways","volume":"10","author":"Kim","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib116","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000063659","article-title":"Activation of caspase-3 during degeneration of the outer nuclear layer in the rd mouse retina","volume":"34","author":"Kim","year":"2002","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib117","doi-asserted-by":"crossref","unstructured":"Kim, S.R., Fishkin, N., Kong J., Nakanishi K., Allikmets R., Sparrow J.R., 2004. Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E. Proc. Natl. Acad. Sci. USA 10.1073\/pnas.0403499101 [doi].","DOI":"10.1073\/pnas.0403499101"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib118","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nature01034","article-title":"The harlequin mouse mutation downregulates apoptosis-inducing factor","volume":"419","author":"Klein","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib119","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1126\/science.290.5497.1717","article-title":"Autophagy as a regulated pathway of cellular degradation","volume":"290","author":"Klionsky","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib120","first-page":"909","article-title":"The retina of c-fos-\/- mice","volume":"41","author":"Kueng-Hitz","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib121","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.preteyeres.2004.03.001","article-title":"Dark adaptation and the retinoid cycle of vision","volume":"23","author":"Lamb","year":"2004","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib122","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1023\/A:1022481306146","article-title":"Viral-mediated FGF-2 treatment of the constant light damage model of photoreceptor degeneration","volume":"106","author":"Lau","year":"2003","journal-title":"Doc. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib123","first-page":"3622","article-title":"Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2","volume":"41","author":"Lau","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib124","first-page":"592","article-title":"Protection of mouse photoreceptors by survival factors in retinal degenerations","volume":"39","author":"LaVail","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib125","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1167\/iovs.03-0093","article-title":"Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retinas of dystrophic Royal College of Surgeons rats","volume":"45","author":"Lawrence","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib126","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/j.freeradbiomed.2004.03.020","article-title":"Cadmium induces caspase-independent apoptosis in liver Hep3B cells","volume":"36","author":"Lemarie","year":"2004","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib127","doi-asserted-by":"crossref","unstructured":"Leveillard, T., Mohand-Said, S., Lorentz, O., Hicks, D., Fintz A.C., Clerin, E., Simonutti, M., Forster, V., Cavusoglu, N., Chalmel, F., Dolle, P., Poch, O., Lambrou, G., Sahel, J.A., 2004. Identification and characterization of rod-derived cone viability factor. Nat. Genet.","DOI":"10.1038\/ng1386"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib128","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0092-8674(00)80434-1","article-title":"Cytochrome c and dATP-dependent formation of Apaf-1\/caspase-9 complex initiates an apoptotic protease cascade","volume":"91","author":"Li","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib129","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/35083620","article-title":"Endonuclease G is an apoptotic DNase when released from mitochondria","volume":"412","author":"Li","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib130","doi-asserted-by":"crossref","first-page":"4968","DOI":"10.1167\/iovs.03-0140","article-title":"Alleviation of constant-light-induced photoreceptor degeneration by adaptation of adult albino rat to bright cyclic light","volume":"44","author":"Li","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib131","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1126\/science.1087621","article-title":"Phosphatidylserine receptor is required for clearance of apoptotic cells","volume":"302","author":"Li","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib132","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1006\/mthe.2001.0473","article-title":"Long-term protection of retinal structure but not function using RAAV. CNTF in animal models of retinitis pigmentosa","volume":"4","author":"Liang","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib133","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1097\/00001756-200104170-00029","article-title":"Melatonin delays photoreceptor degeneration in the rds\/rds mouse","volume":"12","author":"Liang","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib134","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/mthe.2000.0252","article-title":"AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse","volume":"3","author":"Liang","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib135","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/45257","article-title":"Induction of autophagy and inhibition of tumorigenesis by beclin 1","volume":"402","author":"Liang","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib136","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1523\/JNEUROSCI.18-04-01337.1998","article-title":"Preconditioning with bright light evokes a protective response against light damage in the rat retina","volume":"18","author":"Liu","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib137","doi-asserted-by":"crossref","first-page":"4778","DOI":"10.1523\/JNEUROSCI.19-12-04778.1999","article-title":"Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration","volume":"19","author":"Liu","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib138","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1038\/35050006","article-title":"Structural basis for binding of Smac\/DIABLO to the XIAP BIR3 domain","volume":"408","author":"Liu","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib139","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0955-0674(02)00383-6","article-title":"Caspase-independent cell deaths","volume":"14","author":"Lockshin","year":"2002","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib140","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0014-4835(02)92022-1","article-title":"Proteasome function and protein oxidation in the aged retina","volume":"75","author":"Louie","year":"2002","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib141","first-page":"1087","article-title":"Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats","volume":"42","author":"Machida","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib142","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1074\/jbc.M208247200","article-title":"Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy","volume":"278","author":"Marino","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib143","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1074\/jbc.M109784200","article-title":"The serine protease Omi\/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif","volume":"277","author":"Martins","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib144","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/35040009","article-title":"Apoptosis in neurodegenerative disorders","volume":"1","author":"Mattson","year":"2000","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib145","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1006\/mthe.2001.0498","article-title":"Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa","volume":"4","author":"McGee Sanftner","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib146","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0165-6147(00)01771-5","article-title":"Lipoxins","volume":"22","author":"McMahon","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib147","doi-asserted-by":"crossref","first-page":"16391","DOI":"10.1074\/jbc.M010498200","article-title":"NADH oxidase activity of mitochondrial apoptosis-inducing factor","volume":"276","author":"Miramar","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib148","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1002\/eji.200424930","article-title":"Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells","volume":"34","author":"Miyasaka","year":"2004","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib149","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1038\/sj.gt.3302028","article-title":"Simian lentiviral vector-mediated retinal gene transfer of pigment epithelium-derived factor protects retinal degeneration and electrical defect in Royal College of Surgeons rats","volume":"10","author":"Miyazaki","year":"2003","journal-title":"Gene Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib150","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1247\/csf.27.421","article-title":"Autophagosome formation in mammalian cells","volume":"27","author":"Mizushima","year":"2002","journal-title":"Cell Struct. Funct."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib151","first-page":"2344","article-title":"Light exposure induces ubiquitin conjugation and degradation activities in the rat retina","volume":"38","author":"Naash","year":"1997","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib152","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/excr.2000.4834","article-title":"Apoptotic DNA fragmentation","volume":"256","author":"Nagata","year":"2000","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib153","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1089\/10430340050129495","article-title":"Ocular cell transfection with the human basic fibroblast growth factor gene delays photoreceptor cell degeneration in RCS rats","volume":"11","author":"Neuner-Jehle","year":"2000","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib154","first-page":"2383","article-title":"Light treatment enhances photoreceptor survival in dystrophic retinas of Royal College of Surgeons rats","volume":"40","author":"Nir","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib155","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1523\/JNEUROSCI.20-06-02150.2000","article-title":"Expression of Bcl-2 protects against photoreceptor degeneration in retinal degeneration slow (rds) mice","volume":"20","author":"Nir","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib156","first-page":"842","article-title":"Extended photoreceptor viability by light stress in the RCS rats but not in the opsin P23H mutant rats","volume":"42","author":"Nir","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib157","first-page":"450","article-title":"Retinal damage by light in rats","volume":"5","author":"Noell","year":"1966","journal-title":"Invest. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib158","doi-asserted-by":"crossref","first-page":"44566","DOI":"10.1074\/jbc.M205308200","article-title":"Ubiquitylation of the transducin betagamma subunit complex. Regulation by phosducin","volume":"277","author":"Obin","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib159","doi-asserted-by":"crossref","first-page":"4164","DOI":"10.1523\/JNEUROSCI.23-10-04164.2003","article-title":"Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage","volume":"23","author":"Okoye","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib160","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1751-1097.1999.tb07998.x","article-title":"Light-induced damage in the retina","volume":"70","author":"Organisciak","year":"1999","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib161","first-page":"3694","article-title":"Circadian-dependent retinal light damage in rats","volume":"41","author":"Organisciak","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib162","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1167\/iovs.02-0708","article-title":"Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations","volume":"44","author":"Organisciak","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib163","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.toxlet.2003.12.017","article-title":"Mitochondrial regulation of apoptotic cell death","volume":"149","author":"Orrenius","year":"2004","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib164","doi-asserted-by":"crossref","first-page":"3451","DOI":"10.1093\/emboj\/cdg320","article-title":"CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6\/EndoG to promote apoptotic DNA degradation","volume":"22","author":"Parrish","year":"2003","journal-title":"Embo. J."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib165","first-page":"1912","article-title":"Absence of photoreceptor rescue with D-cis-diltiazem in the rd mouse","volume":"43","author":"Pawlyk","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib166","first-page":"42","article-title":"Calcium channel blocker D-cis-diltiazem does not slow retinal degeneration in the PDE6B mutant rcd1 canine model of retinitis pigmentosa","volume":"7","author":"Pearce-Kelling","year":"2001","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib167","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S1350-9462(00)00025-2","article-title":"Immunological and aetiological aspects of macular degeneration","volume":"20","author":"Penfold","year":"2001","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib168","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nrm1336","article-title":"Proteasomes and their kin","volume":"5","author":"Pickart","year":"2004","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib169","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0165-6147(99)01292-4","article-title":"Poly (ADP-ribose) polymerase, nitric oxide and cell death","volume":"20","author":"Pieper","year":"1999","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib170","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1073\/pnas.91.3.974","article-title":"Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa","volume":"91","author":"Portera-Cailliau","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib171","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1073\/pnas.91.3.974","article-title":"Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa","volume":"91","author":"Portera-Cailliau","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib172","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1172\/JCI20039","article-title":"Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene","volume":"112","author":"Qu","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib173","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.1073\/pnas.0737855100","article-title":"Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration","volume":"100","author":"Radu","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib174","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1073\/pnas.0308302101","article-title":"Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration","volume":"101","author":"Radu","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib175","first-page":"1191","article-title":"Functional protection of photoreceptors from light-induced damage by dimethylthiourea and Ginkgo biloba extract","volume":"40","author":"Ranchon","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib176","first-page":"1375","article-title":"Systemic administration of phenyl-N-tert-butylnitrone protects the retina from light damage","volume":"42","author":"Ranchon","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib177","doi-asserted-by":"crossref","first-page":"6050","DOI":"10.1523\/JNEUROSCI.23-14-06050.2003","article-title":"Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration","volume":"23","author":"Ranchon","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib178","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0014-4835(02)92034-8","article-title":"Absence of voltage-dependent calcium channels delays photoreceptor degeneration in rd mice","volume":"75","author":"Read","year":"2002","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib179","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/3813","article-title":"Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle","volume":"20","author":"Redmond","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib180","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.3109\/02713689508998521","article-title":"Lipid mediators in the rat retina","volume":"14","author":"Reinboth","year":"1995","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib181","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1006\/exer.1996.0116","article-title":"Light elicits the release of docosahexaenoic acid from membrane phospholipids in the rat retina in vitro","volume":"63","author":"Reinboth","year":"1996","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib182","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/0006-8993(86)90550-0","article-title":"Circadian rhythm in the light response of rat retinal disk-shedding and autophagy","volume":"369","author":"Reme","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib183","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/074873049100600104","article-title":"The visual input stage of the mammalian circadian pacemaking system. I. Is there a clock in the mammalian eye?","volume":"6","author":"Reme","year":"1991","journal-title":"J. Biol. Rhythms"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib184","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1350-9462(98)00009-3","article-title":"Apoptotic cell death in retinal degenerations","volume":"17","author":"Reme","year":"1998","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib185","series-title":"The Retinal Pigment Epithelium. Function and Disease","first-page":"563","article-title":"Light damage to retina and retinal pigment epithelium","author":"Reme","year":"1998"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib186","first-page":"2398","article-title":"Photoreceptor autophagy","volume":"40","author":"Reme","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib187","first-page":"120","article-title":"Apoptosis in the retina","volume":"15","author":"Reme","year":"2000","journal-title":"News Physiol. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib188","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1023\/A:1022423724376","article-title":"Why study rod cell death in retinal degenerations and how?","volume":"106","author":"Reme","year":"2003","journal-title":"Doc. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib189","unstructured":"Reme, C.E., Grimm, C., Simon, M.I., Wenzel, A., 2003b. Effects of blue- and green light in arresting\/rhodopsinkinase double knock out (Arr\u2212\/\u2212\/RK\u2212\/\u2212) mice. Invest Ophthalmol Vis Sci 43: ARVO E-Abstract 5132."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib190","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/(SICI)1097-4695(19970605)32:6<593::AID-NEU5>3.0.CO;2-V","article-title":"Aberrant expression of c-Fos accompanies photoreceptor cell death in the rd mouse","volume":"32","author":"Rich","year":"1997","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib191","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0014-4835(02)00258-0","article-title":"Lack of p75 receptor does not protect photoreceptors from light-induced cell death","volume":"76","author":"Rohrer","year":"2003","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib192","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S0042-6989(97)00198-3","article-title":"Reduction of all-trans-retinal limits regeneration of visual pigment in mice","volume":"38","author":"Saari","year":"1998","journal-title":"Vis. Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib193","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0896-6273(01)00248-3","article-title":"Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation","volume":"29","author":"Saari","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib194","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0006-291X(03)01092-1","article-title":"Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis","volume":"306","author":"Sato","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib195","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1038\/nri957","article-title":"A blast from the past","volume":"2","author":"Savill","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib196","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/sj.cdd.4400817","article-title":"Phosphatidylserine, a death knell","volume":"8","author":"Schlegel","year":"2001","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib197","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/sj.gt.3301929","article-title":"Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2Rd2\/Rd2 model of retinal degeneration","volume":"10","author":"Schlichtenbrede","year":"2003","journal-title":"Gene Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib198","first-page":"2303","article-title":"Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin","volume":"41","author":"Schutt","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib199","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.exer.2003.10.003","article-title":"Function of the ubiquitin proteolytic pathway in the eye","volume":"78","author":"Shang","year":"2004","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib200","doi-asserted-by":"crossref","unstructured":"Sharma, A.K., Rohrer, B., 2004. Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line. J. Biol. Chem.","DOI":"10.1074\/jbc.M401037200"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib201","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.bbamcr.2003.10.016","article-title":"Control of mitochondrial permeability by Bcl-2 family members","volume":"1644","author":"Sharpe","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib202","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S1350-9462(02)00007-1","article-title":"LEDGF, a survival factor, activates stress-related genes","volume":"21","author":"Shinohara","year":"2002","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib203","doi-asserted-by":"crossref","first-page":"5234","DOI":"10.1093\/emboj\/18.19.5234","article-title":"Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast","volume":"18","author":"Shintani","year":"1999","journal-title":"Embo. J."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib204","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1073\/pnas.041606498","article-title":"Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy","volume":"98","author":"Sieving","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib205","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S1357-4310(96)10057-5","article-title":"Age-related macular degeneration","volume":"3","author":"Silvestri","year":"1997","journal-title":"Mol. Med. Today"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib206","first-page":"1222","article-title":"Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE","volume":"43","author":"Sparrow","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib207","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1751-1097.1999.tb05311.x","article-title":"Damage to rat retinal DNA induced in vivo by visible light","volume":"69","author":"Specht","year":"1999","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib208","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1562\/0031-8655(2000)071<0559:CDTRRD>2.0.CO;2","article-title":"Continuing damage to rat retinal DNA during darkness following light exposure","volume":"71","author":"Specht","year":"2000","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib209","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1006\/mthe.2001.0307","article-title":"HSV-1 vector-delivered FGF2 to the retina is neuroprotective but does not preserve functional responses","volume":"3","author":"Spencer","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib210","doi-asserted-by":"crossref","first-page":"14376","DOI":"10.1073\/pnas.97.26.14376","article-title":"An alternative, nonapoptotic form of programmed cell death","volume":"97","author":"Sperandio","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib211","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1074\/jbc.M008944200","article-title":"Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route","volume":"276","author":"Stoka","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib212","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.biochem.69.1.217","article-title":"Apoptosis signaling","volume":"69","author":"Strasser","year":"2000","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib213","first-page":"2458","article-title":"The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat","volume":"39","author":"Sugawara","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib214","doi-asserted-by":"crossref","first-page":"11766","DOI":"10.1074\/jbc.M010152200","article-title":"ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease","volume":"276","author":"Sun","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib215","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S1097-2765(04)00156-X","article-title":"Caspase activation inhibits proteasome function during apoptosis","volume":"14","author":"Sun","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib216","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/17135","article-title":"Molecular characterization of mitochondrial apoptosis-inducing factor","volume":"397","author":"Susin","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib217","doi-asserted-by":"crossref","first-page":"39625","DOI":"10.1074\/jbc.M007049200","article-title":"Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells","volume":"275","author":"Suter","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib218","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S1097-2765(01)00341-0","article-title":"A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death","volume":"8","author":"Suzuki","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib219","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/nrn1174","article-title":"The biochemistry of neuronal necrosis","volume":"4","author":"Syntichaki","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib220","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.bbrc.2003.12.034","article-title":"Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse","volume":"313","author":"Takano","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib221","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1091\/mbc.10.5.1367","article-title":"Apg7p\/Cvt2p","volume":"10","author":"Tanida","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib222","first-page":"1162","article-title":"Cytoprotective effect of thioredoxin against retinal photic injury in mice","volume":"43","author":"Tanito","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib223","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0304-3940(02)00314-2","article-title":"Attenuation of retinal photooxidative damage in thioredoxin transgenic mice","volume":"326","author":"Tanito","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib224","first-page":"3292","article-title":"Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa","volume":"43","author":"Tao","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib225","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0306-4522(99)00550-3","article-title":"c-Jun\/AP-1 (N) directed antibodies cross-react with \u201capoptosis-specific protein\u201d which marks an autophagic process during neuronal apoptosis","volume":"96","author":"Terwel","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib226","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.1242\/jcs.00829","article-title":"Bcl-2 on the endoplasmic reticulum","volume":"116","author":"Thomenius","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib227","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1001\/archopht.122.5.750","article-title":"Sunlight and the 10-year incidence of age-related maculopathy","volume":"122","author":"Tomany","year":"2004","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib228","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/nrn1176","article-title":"PEDF","volume":"4","author":"Tombran-Tink","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib229","first-page":"943","article-title":"Retarding photoreceptor degeneration in Pdegtm1\/Pdegtml mice by an apoptosis suppressor gene","volume":"38","author":"Tsang","year":"1997","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib230","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1073\/pnas.96.6.3126","article-title":"Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats","volume":"96","author":"Uteza","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib231","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1038\/sj.cdd.4400944","article-title":"Endonuclease G","volume":"8","author":"van Loo","year":"2001","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib232","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0039-6257(98)00046-0","article-title":"Retinitis pigmentosa","volume":"43","author":"van Soest","year":"1999","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib233","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1084\/jem.188.5.919","article-title":"Dual signaling of the Fas receptor","volume":"188","author":"Vercammen","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib234","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0092-8674(00)00009-X","article-title":"Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins","volume":"102","author":"Verhagen","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib235","unstructured":"Vision research conference, 2003. Retinal cell rescue: stem cells, remodelling, neuroprotection, apoptosis and replacement of retinal neurons. Proceedings of the 6th Annual Vision Research Conference. Ft. Lauderdale, Florida, USA. May 3\u20134."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib236","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1126\/science.1076194","article-title":"Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans","volume":"298","author":"Wang","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib237","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1523\/JNEUROSCI.20-01-00081.2000","article-title":"c-fos controls the \u201cprivate pathway\u201d of light-induced apoptosis of retinal photoreceptors","volume":"20","author":"Wenzel","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib238","first-page":"1653","article-title":"Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor","volume":"42","author":"Wenzel","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib239","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1523\/JNEUROSCI.21-01-00053.2001","article-title":"The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration","volume":"21","author":"Wenzel","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib240","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1046\/j.0022-3042.2002.00807.x","article-title":"Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis","volume":"80","author":"Wenzel","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib241","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1167\/iovs.02-1134","article-title":"The genetic modifier Rpe65Leu(450)","volume":"44","author":"Wenzel","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib242","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1582-4934.2002.tb00309.x","article-title":"Regulation of apoptosis by the ubiquitin and proteasome pathway","volume":"6","author":"Wojcik","year":"2002","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib243","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1084\/jem.180.6.2113","article-title":"Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation","volume":"180","author":"Wright","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib244","first-page":"3349","article-title":"Involvement of caspase-3 in photoreceptor cell apoptosis induced by in vivo blue light exposure","volume":"43","author":"Wu","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib245","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0006-8993(02)04125-2","article-title":"Light-induced photoreceptor degeneration may involve the NF kappa B\/caspase-1 pathway in vivo","volume":"967","author":"Wu","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib246","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1073\/pnas.98.1.11","article-title":"More than one way to go","volume":"98","author":"Wyllie","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib247","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1006\/mcne.1999.0780","article-title":"Autophagy is activated by apoptotic signalling in sympathetic neurons","volume":"14","author":"Xue","year":"1999","journal-title":"Mol. Cell Neurosci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib248","first-page":"919","article-title":"Preservation of retinal morphology and functions in royal college surgeons rat by nilvadipine, a Ca(2+) antagonist","volume":"43","author":"Yamazaki","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib249","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1167\/iovs.02-0768","article-title":"Blue light-induced generation of reactive oxygen species in photoreceptor ellipsoids requires mitochondrial electron transport","volume":"44","author":"Yang","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib250","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/nsb836","article-title":"DNA binding is required for the apoptogenic action of apoptosis inducing factor","volume":"9","author":"Ye","year":"2002","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib251","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s00417-002-0427-5","article-title":"Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene","volume":"240","author":"Yoshizawa","year":"2002","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib252","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.1072221","article-title":"Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor","volume":"297","author":"Yu","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib253","doi-asserted-by":"crossref","first-page":"15077","DOI":"10.1073\/pnas.2436255100","article-title":"Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor","volume":"100","author":"Yue","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.preteyeres.2004.08.002_bib254","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1167\/iovs.03-0439","article-title":"Caspase-3 in postnatal retinal development and degeneration","volume":"45","author":"Zeiss","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2004.08.002_bib255","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s003470170140","article-title":"\u201cRetinal implants\u201d\u2014replacement of retinal functions by technical implants","volume":"98","author":"Zrenner","year":"2001","journal-title":"Ophthalmologe"}],"container-title":["Progress in Retinal and Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350946204000710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350946204000710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T01:26:22Z","timestamp":1585963582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1350946204000710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":255,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S1350946204000710"],"URL":"https:\/\/doi.org\/10.1016\/j.preteyeres.2004.08.002","relation":{},"ISSN":["1350-9462"],"issn-type":[{"value":"1350-9462","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}