{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,15]],"date-time":"2026-11-15T03:42:32Z","timestamp":1794714152337,"version":"4.9.1"},"reference-count":317,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Retinal and Eye Research"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.preteyeres.2024.101276","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T06:18:40Z","timestamp":1717222720000},"page":"101276","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"C","title":["Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice \u2013 Developments over 25 years"],"prefix":"10.1016","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3586-0492","authenticated-orcid":false,"given":"Frederik","family":"Raiskup","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Herber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Lenk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz E.","family":"Pillunat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberhard","family":"Spoerl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.preteyeres.2024.101276_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.109267","article-title":"Repeated application of riboflavin during corneal cross-linking does not improve the biomechanical stiffening effect ex vivo","volume":"224","author":"Abdshahzadeh","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1136\/bjo.2007.130104","article-title":"Non-destructive mechanical characterisation of UVA\/riboflavin crosslinked collagen hydrogels","volume":"92","author":"Ahearne","year":"2008","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib3","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2945751","article-title":"Simultaneous transepithelial topography-guided photorefractive keratectomy and accelerated cross-linking in keratoconus: 2-year follow-up","volume":"2018","author":"Ahmet","year":"2018","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.preteyeres.2024.101276_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108839","article-title":"Corneal biomechanical properties following corneal cross-linking: does age have an effect?","volume":"214","author":"Alenezi","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib5","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ajo.2012.07.004","article-title":"Photorefractive keratectomy followed by cross-linking versus cross-linking alone for management of progressive keratoconus: two-year follow-up","volume":"155","author":"Alessio","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib6","doi-asserted-by":"crossref","first-page":"434","DOI":"10.3928\/1081597X-20170426-02","article-title":"Integration of scheimpflug-based corneal tomography and biomechanical assessments for enhancing ectasia detection","volume":"33","author":"Ambrosio","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib7","article-title":"Optimized artificial intelligence for enhanced ectasia detection using Scheimpflug-based corneal tomography and biomechanical data","author":"Ambrosio","year":"2022","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib8","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0014-4835(80)80027-3","article-title":"Biomechanical properties of keratoconus and normal corneas","volume":"31","author":"Andreassen","year":"1980","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib9","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1097\/ICO.0000000000000185","article-title":"UV cross-linking of donor corneas confers resistance to keratolysis","volume":"33","author":"Arafat","year":"2014","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib10","first-page":"3","article-title":"[The role of tear acidity and Cu-cofactor of lysyl oxidase activity in the pathogenesis of keratoconus]","volume":"127","author":"Avetisov","year":"2011","journal-title":"Vestn. Oftalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib11","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1097\/ICO.0b013e31823cbeb1","article-title":"Endothelial failure after collagen cross-linking with riboflavin and UV-A: case report with literature review","volume":"31","author":"Bagga","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0047-6374(98)00119-5","article-title":"Mechanisms of maturation and ageing of collagen","volume":"106","author":"Bailey","year":"1998","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.preteyeres.2024.101276_bib13","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1111\/aos.14082","article-title":"Incidence and prevalence of keratoconus in Denmark - an update","volume":"97","author":"Bak-Nielsen","year":"2019","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/aos.13961","article-title":"A nationwide population-based study of social demographic factors, associated diseases and mortality of keratoconus patients in Denmark from 1977 to 2015","volume":"97","author":"Bak-Nielsen","year":"2019","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib15","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3928\/1081597X-20171025-01","article-title":"Changes in corneal biomechanical properties with different corneal cross-linking irradiances","volume":"34","author":"Bao","year":"2018","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib16","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/bjo.84.8.834","article-title":"Atopy and keratoconus: a multivariate analysis","volume":"84","author":"Bawazeer","year":"2000","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/APO.0000000000000333","article-title":"Determining progression in ectatic corneal disease","volume":"9","author":"Belin","year":"2020","journal-title":"Asia Pac. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib18","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1097\/ICO.0000000000001707","article-title":"Corneal cross-linking: current USA status: report from the cornea society","volume":"37","author":"Belin","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib19","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1167\/iovs.13-13042","article-title":"Biomechanical changes after repeated collagen cross-linking on human corneas assessed in vitro using scanning acoustic microscopy","volume":"55","author":"Beshtawi","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib20","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1097\/ICO.0b013e3182068adc","article-title":"Pregnancy-induced progression of keratoconus","volume":"30","author":"Bilgihan","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bpj.2011.05.029","article-title":"Quantification of collagen organization in the peripheral human cornea at micron-scale resolution","volume":"101","author":"Boote","year":"2011","journal-title":"Biophys. J."},{"key":"10.1016\/j.preteyeres.2024.101276_bib22","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1136\/bjo.85.4.379","article-title":"The architecture of the corneal stroma","volume":"85","author":"Bron","year":"2001","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib23","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1007\/s10792-020-01512-3","article-title":"Complications of accelerated corneal collagen cross-linking: review of 2025 eyes","volume":"40","author":"Cakmak","year":"2020","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib24","first-page":"63","article-title":"Collagen crosslinking in keratoconus","volume":"17","author":"Cannon","year":"1978","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib25","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ajo.2009.10.021","article-title":"Long-term results of riboflavin ultraviolet a corneal collagen cross-linking for keratoconus in Italy: the Siena eye cross study","volume":"149","author":"Caporossi","year":"2010","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib26","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/608041","article-title":"Age-related long-term functional results after riboflavin UV A corneal cross-linking","volume":"2011","author":"Caporossi","year":"2011","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib27","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/ICO.0b013e31822159f6","article-title":"Riboflavin-UVA-induced corneal collagen cross-linking in pediatric patients","volume":"31","author":"Caporossi","year":"2012","journal-title":"Cornea"},{"issue":"Suppl. 7","key":"10.1016\/j.preteyeres.2024.101276_bib28","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.5301\/ejo.5000125","article-title":"Transepithelial corneal collagen crosslinking for keratoconus: qualitative investigation by in vivo HRT II confocal analysis","volume":"22","author":"Caporossi","year":"2012","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib29","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.jcrs.2013.03.026","article-title":"Transepithelial corneal collagen crosslinking for progressive keratoconus: 24-month clinical results","volume":"39","author":"Caporossi","year":"2013","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib30","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/ICO.0000000000000699","article-title":"Transepithelial corneal cross-linking with vitamin E-enhanced riboflavin solution and abbreviated, low-dose UV-A: 24-month clinical outcomes","volume":"35","author":"Caruso","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib31","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1167\/iovs.13-12595","article-title":"Iontophoresis transcorneal delivery technique for transepithelial corneal collagen crosslinking with riboflavin in a rabbit model","volume":"57","author":"Cassagne","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib32","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3928\/1081597X-20170201-02","article-title":"Customized topography-guided corneal collagen cross-linking for keratoconus","volume":"33","author":"Cassagne","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib33","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3928\/1081597X-20180220-01","article-title":"The relationship between mechanical properties, ultrastructural changes, and intrafibrillar bond formation in corneal UVA\/riboflavin cross-linking treatment for keratoconus","volume":"34","author":"Chang","year":"2018","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib34","doi-asserted-by":"crossref","first-page":"753","DOI":"10.3928\/1081597X-20121011-01","article-title":"Progression of keratoconus and efficacy of pediatric corrected corneal collagen cross-linking in children and adolescents","volume":"28","author":"Chatzis","year":"2012","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib35","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.32604\/biocell.2021.014873","article-title":"Three-month effects of corneal cross-linking on corneal fibroblasts","volume":"45","author":"Chen","year":"2021","journal-title":"Biocell"},{"key":"10.1016\/j.preteyeres.2024.101276_bib36","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1167\/iovs.11-8118","article-title":"Progression of keratoconus by longitudinal assessment with corneal topography","volume":"53","author":"Choi","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib37","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/sj.eye.6701677","article-title":"Influence of ethnic origin on the incidence of keratoconus and associated atopic disease in Asian and white patients","volume":"19","author":"Cozma","year":"2005","journal-title":"Eye"},{"key":"10.1016\/j.preteyeres.2024.101276_bib38","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1367-0484(03)00022-5","article-title":"The cascade hypothesis of keratoconus","volume":"26","author":"Cristina Kenney","year":"2003","journal-title":"Contact Lens Anterior Eye : J. Br. Contact Lens Assoc."},{"key":"10.1016\/j.preteyeres.2024.101276_bib39","doi-asserted-by":"crossref","first-page":"638","DOI":"10.3928\/1081597X-20091111-01","article-title":"Sequential in vivo confocal microscopy study of corneal wound healing after cross-linking in patients with keratoconus","volume":"26","author":"Croxatto","year":"2010","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib40","doi-asserted-by":"crossref","first-page":"2556","DOI":"10.1167\/iovs.10-6620","article-title":"High-resolution, noninvasive, two-photon fluorescence measurement of molecular concentrations in corneal tissue","volume":"52","author":"Cui","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib41","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1097\/ICO.0000000000000823","article-title":"Optimizing corneal cross-linking in the treatment of keratoconus: a comparison of outcomes after standard- and high-intensity protocols","volume":"35","author":"Cummings","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib42","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1442-9071.2011.02681.x","article-title":"Trends in the distribution of donor corneal tissue and indications for corneal transplantation: the New Zealand National Eye Bank Study 2000-2009","volume":"40","author":"Cunningham","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib43","first-page":"121","article-title":"Collagen fibril orientation in the human corneal stroma and its implication in keratoconus","volume":"38","author":"Daxer","year":"1997","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib44","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1136\/bjophthalmol-2019-314954","article-title":"Multicentre study: reliability and repeatability of Scheimpflug system measurement in keratoconus","volume":"105","author":"de Luis Eguileor","year":"2021","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib45","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jcrs.2010.12.037","article-title":"Anatomy and physiology of the cornea","volume":"37","author":"DelMonte","year":"2011","journal-title":"J. Cataract Refract. Surg."},{"issue":"Suppl. 7","key":"10.1016\/j.preteyeres.2024.101276_bib46","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.5301\/ejo.5000114","article-title":"Riboflavin's time-dependent degradation rate induced by ultraviolet A irradiation","volume":"22","author":"Diakonis","year":"2012","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib47","first-page":"289","article-title":"Effects of topical ozone application on outcomes after accelerated corneal collagen cross-linking: an experimental study","volume":"15","author":"Dogan","year":"2020","journal-title":"J. Ophthalmic Vis. Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib48","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41421-022-00397-z","article-title":"Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis","volume":"8","author":"Dou","year":"2022","journal-title":"Cell Discov."},{"key":"10.1016\/j.preteyeres.2024.101276_bib49","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1444-0938.2007.00195.x","article-title":"New perspectives on keratoconus as revealed by corneal confocal microscopy","volume":"91","author":"Efron","year":"2008","journal-title":"Clin. Exp. Optom."},{"key":"10.1016\/j.preteyeres.2024.101276_bib50","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3928\/1081597X-20160920-03","article-title":"Comparison of corneal riboflavin gradients using dextran and HPMC solutions","volume":"32","author":"Ehmke","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib51","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1098\/rsif.2005.0034","article-title":"Comparative study of corneal strip extensometry and inflation tests","volume":"2","author":"Elsheikh","year":"2005","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.preteyeres.2024.101276_bib52","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/02713680601077145","article-title":"Assessment of corneal biomechanical properties and their variation with age","volume":"32","author":"Elsheikh","year":"2007","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib53","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1097\/ICO.0b013e31817f815a","article-title":"Keratoconus clinical findings according to different age and gender groups","volume":"27","author":"Ertan","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib54","series-title":"Statistical Report on Eye Banking Activity for 2004","year":"2005"},{"key":"10.1016\/j.preteyeres.2024.101276_bib55","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1136\/bjophthalmol-2020-317547","article-title":"Predictors of progression in untreated keratoconus: a save sight keratoconus registry study","volume":"106","author":"Ferdi","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib56","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jcrs.2011.08.030","article-title":"Transepithelial corneal collagen crosslinking: bilateral study","volume":"38","author":"Filippello","year":"2012","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib57","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1080\/02713683.2023.2205612","article-title":"Analysis of biomechanical response after corneal crosslinking with different fluence levels in porcine corneas","volume":"48","author":"Fischinger","year":"2023","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib58","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3928\/1081597X-20160428-02","article-title":"Transepithelial corneal cross-linking using an enhanced riboflavin solution","volume":"32","author":"Gatzioufas","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib59","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ajo.2016.12.015","article-title":"Age-specific incidence and prevalence of keratoconus: a nationwide registration study","volume":"175","author":"Godefrooij","year":"2017","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib60","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/aos.13095","article-title":"Nationwide reduction in the number of corneal transplantations for keratoconus following the implementation of cross-linking","volume":"94","author":"Godefrooij","year":"2016","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib61","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.2147\/OPTH.S139358","article-title":"Higher order optical aberrations and visual acuity in a randomized controlled trial comparing transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus","volume":"11","author":"Godefrooij","year":"2017","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib62","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.ophtha.2017.04.011","article-title":"Cost-effectiveness analysis of corneal collagen crosslinking for progressive keratoconus","volume":"124","author":"Godefrooij","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib63","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1097\/ICO.0000000000000819","article-title":"Corneal cross-linking for pediatric keratoconus: long-term results","volume":"35","author":"Godefrooij","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib64","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/ICO.0b013e318190734d","article-title":"Can we measure corneal biomechanical changes after collagen cross-linking in eyes with keratoconus?--a pilot study","volume":"28","author":"Goldich","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib65","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/ICO.0000000000000408","article-title":"Global consensus on keratoconus and ectatic diseases","volume":"34","author":"Gomes","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib66","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.jcrs.2018.03.026","article-title":"Combined wavefront-guided transepithelial photorefractive keratectomy and corneal crosslinking for visual rehabilitation in moderate keratoconus","volume":"44","author":"Gore","year":"2018","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib67","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1016\/j.jcrs.2010.06.067","article-title":"Natural history of corneal haze after collagen crosslinking for keratoconus and corneal ectasia: Scheimpflug and biomicroscopic analysis","volume":"36","author":"Greenstein","year":"2010","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib68","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jcrs.2011.08.041","article-title":"Higher-order aberrations after corneal collagen crosslinking for keratoconus and corneal ectasia","volume":"38","author":"Greenstein","year":"2012","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib69","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/ICO.0b013e31821eea66","article-title":"In vivo biomechanical changes after corneal collagen cross-linking for keratoconus and corneal ectasia: 1-year analysis of a randomized, controlled, clinical trial","volume":"31","author":"Greenstein","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib70","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jcrs.2008.11.046","article-title":"Corneal collagen crosslinking using riboflavin and ultraviolet-A light for keratoconus: one-year analysis using Scheimpflug imaging","volume":"35","author":"Grewal","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib71","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ajo.2020.12.028","article-title":"The interday repeatability of parameters for the assessment of progressive disease in subjects with less advanced keratoconus","volume":"225","author":"Gustafsson","year":"2021","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib72","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1097\/ICO.0b013e31820143d1","article-title":"Limitation of collagen cross-linking with hypoosmolar riboflavin solution: failure in an extremely thin cornea","volume":"30","author":"Hafezi","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib73","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jcrs.2008.02.036","article-title":"Pregnancy-related exacerbation of iatrogenic keratectasia despite corneal collagen crosslinking","volume":"34","author":"Hafezi","year":"2008","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib74","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ajo.2020.12.011","article-title":"Individualized corneal cross-linking with riboflavin and UV-A in ultrathin corneas: the Sub400 protocol","volume":"224","author":"Hafezi","year":"2021","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib75","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jcrs.2008.10.060","article-title":"Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas","volume":"35","author":"Hafezi","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib76","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3928\/1081597X-20201123-02","article-title":"Corneal cross-linking at the slit lamp","volume":"37","author":"Hafezi","year":"2021","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib77","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/ICU.0000000000000967","article-title":"Expanding indications for corneal cross-linking","volume":"34","author":"Hafezi","year":"2023","journal-title":"Curr. Opin. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib78","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jcrs.2017.01.013","article-title":"Collagen crosslinking with conventional and accelerated ultraviolet-A irradiation using riboflavin with hydroxypropyl methylcellulose","volume":"43","author":"Hagem","year":"2017","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib79","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1167\/iovs.13-13748","article-title":"Corneal biomechanical properties at different corneal cross-linking (CXL) irradiances","volume":"55","author":"Hammer","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib80","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jbiomech.2019.06.011","article-title":"Two-year changes in corneal stiffness parameters after accelerated corneal cross-linking","volume":"93","author":"Hashemi","year":"2019","journal-title":"J. Biomech."},{"key":"10.1016\/j.preteyeres.2024.101276_bib81","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/ICO.0000000000002150","article-title":"The prevalence and risk factors for keratoconus: a systematic review and meta-analysis","volume":"39","author":"Hashemi","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib82","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.ajo.2015.08.027","article-title":"Long-term results of an accelerated corneal cross-linking protocol (18 mW\/cm2) for the treatment of progressive keratoconus","volume":"160","author":"Hashemi","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib83","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052860","article-title":"The effect of riboflavin\/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma","volume":"8","author":"Hayes","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2024.101276_bib84","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/1120672118760149","article-title":"Long-term efficacy and safety after corneal collagen crosslinking in pediatric patients: three-year follow-up","volume":"28","author":"Henriquez","year":"2018","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108498","article-title":"Depth- and direction-dependent changes in solute transport following cross-linking with riboflavin and UVA light in ex vivo porcine cornea","volume":"205","author":"Hepfer","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib86","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1097\/ICO.0000000000003219","article-title":"Evaluation of biomechanical changes after accelerated cross-linking in progressive keratoconus: a prospective follow-up study","volume":"42","author":"Herber","year":"2023","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib87","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1007\/s00417-020-04792-8","article-title":"Comparison of waveform-derived corneal stiffness and stress-strain extensometry-derived corneal stiffness using different cross-linking irradiances: an experimental study with air-puff applanation of ex vivo porcine eyes","volume":"258","author":"Herber","year":"2020","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib88","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3928\/1081597X-20220601-01","article-title":"Evaluation of corneal biomechanical indices in distinguishing between normal, very asymmetric, and bilateral keratoconic eyes","volume":"38","author":"Herber","year":"2022","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib89","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jcrs.2018.03.025","article-title":"Influence of the beam profile crosslinking setting on changes in corneal topography and tomography in progressive keratoconus: preliminary results","volume":"44","author":"Herber","year":"2018","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib90","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40662-022-00290-6","article-title":"Comparison of corneal tomography using a novel swept-source optical coherence tomographer and rotating Scheimpflug system in normal and keratoconus eyes: repeatability and agreement analysis","volume":"9","author":"Herber","year":"2022","journal-title":"Eye Vis."},{"key":"10.1016\/j.preteyeres.2024.101276_bib91","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.jcrs.2018.12.015","article-title":"Assessment of corneal biomechanical parameters in healthy and keratoconic eyes using dynamic bidirectional applanation device and dynamic Scheimpflug analyzer","volume":"45","author":"Herber","year":"2019","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib92","first-page":"5210","article-title":"Classification of dynamic corneal response parameters concerning the topographical severity of keratoconus using the dynamic Scheimpflug imaging and machine-learning algorithms","volume":"61","author":"Herber","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib93","first-page":"86","article-title":"Repeatability and reproducibility of corneal deformation response parameters of dynamic ultra-high-speed Scheimpflug imaging in keratoconus","volume":"46","author":"Herber","year":"2020","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib94","doi-asserted-by":"crossref","DOI":"10.1097\/j.jcrs.0000000000001136","article-title":"Repeatability of corneal deformation response parameters by dynamic ultra-high speed Scheimpflug imaging before and after corneal cross-linking Repeatability of corneal deformation before and after CXL","author":"Herber","year":"2023","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib95","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1350-9462(99)00017-8","article-title":"The optic nerve head in glaucoma: role of astrocytes in tissue remodeling","volume":"19","author":"Hernandez","year":"2000","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib96","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jcrs.2010.07.030","article-title":"Corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results","volume":"37","author":"Hersh","year":"2011","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib97","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.ophtha.2017.05.036","article-title":"U.S. Multicenter clinical trial of corneal collagen crosslinking for treatment of corneal ectasia after refractive surgery","volume":"124","author":"Hersh","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib98","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.ophtha.2017.03.052","article-title":"United States multicenter clinical trial of corneal collagen crosslinking for keratoconus treatment","volume":"124","author":"Hersh","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib99","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1080\/02713683.2019.1669663","article-title":"Optimization of oxygen dynamics, UV-A delivery, and Drug formulation for accelerated epi-on corneal crosslinking","volume":"45","author":"Hill","year":"2020","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib100","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/OPX.0b013e318279eb87","article-title":"Corneal deformation measurement using Scheimpflug noncontact tonometry","volume":"90","author":"Hon","year":"2013","journal-title":"Optom. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib101","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ajo.2017.10.003","article-title":"Use of donors predisposed by corneal collagen cross-linking in penetrating keratoplasty for treating patients with keratoconus","volume":"184","author":"Huang","year":"2017","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib102","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40662-020-00179-2","article-title":"Changes in higher order aberrations after central corneal regularization - a comparative two-year analysis of a semi-automated topography-guided photorefractive keratectomy combined with corneal cross-linking","volume":"7","author":"Iselin","year":"2020","journal-title":"Eye Vis."},{"key":"10.1016\/j.preteyeres.2024.101276_bib103","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1177\/1120672120944798","article-title":"Corneal biomechanical outcome of collagen cross-linking in keratoconic patients evaluated by Corvis ST","volume":"31","author":"Jabbarvand","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib104","doi-asserted-by":"crossref","first-page":"366","DOI":"10.3928\/1081597X-20140523-01","article-title":"Contact lens-assisted collagen cross-linking (CACXL): a new technique for cross-linking thin corneas","volume":"30","author":"Jacob","year":"2014","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib105","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1080\/10255842.2015.1077515","article-title":"Development and validation of a correction equation for Corvis tonometry","volume":"19","author":"Joda","year":"2016","journal-title":"Comput. Methods Biomech. Biomed. Eng."},{"key":"10.1016\/j.preteyeres.2024.101276_bib106","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1165\/ajrcmb\/5.3.206","article-title":"Properties and function of lysyl oxidase","volume":"5","author":"Kagan","year":"1991","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib107","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1167\/iovs.11-9385","article-title":"Photochemical kinetics of corneal cross-linking with riboflavin","volume":"53","author":"Kamaev","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib108","doi-asserted-by":"crossref","first-page":"478","DOI":"10.3928\/1081597X-20190627-01","article-title":"Ten-year outcomes of progressive keratoconus management with the athens protocol (Topography-Guided partial-refraction PRK combined with CXL)","volume":"35","author":"Kanellopoulos","year":"2019","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib109","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3928\/1081597X-20101105-01","article-title":"Management of corneal ectasia after LASIK with combined, same-day, topography-guided partial transepithelial PRK and collagen cross-linking: the athens protocol","volume":"27","author":"Kanellopoulos","year":"2011","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib110","doi-asserted-by":"crossref","first-page":"731","DOI":"10.3928\/1081597X-20200820-01","article-title":"Accelerated epithelium-off corneal cross-linking with high ultraviolet energy dose (7.2 J\/cm(2)) for progressive keratoconus: 2-year results in a Chinese population","volume":"36","author":"Kang","year":"2020","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib111","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0006-291X(82)90612-X","article-title":"Increased collagenase and gelatinase activities in keratoconus","volume":"107","author":"Kao","year":"1982","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.preteyeres.2024.101276_bib112","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1046\/j.1523-1747.2003.12092.x","article-title":"Effect of smoking and sun on the aging skin","volume":"120","author":"Kennedy","year":"2003","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib113","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0002-9394(86)90817-2","article-title":"A 48-year clinical and epidemiologic study of keratoconus","volume":"101","author":"Kennedy","year":"1986","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib114","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3109\/02713683.2010.481068","article-title":"Pharmacological modification of the epithelial permeability by benzalkonium chloride in UVA\/Riboflavin corneal collagen cross-linking","volume":"35","author":"Kissner","year":"2010","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib115","doi-asserted-by":"crossref","first-page":"840","DOI":"10.3928\/1081597X-20151111-08","article-title":"Increased biomechanical efficacy of corneal cross-linking in thin corneas due to higher oxygen availability","volume":"31","author":"Kling","year":"2015","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib116","doi-asserted-by":"crossref","first-page":"4324","DOI":"10.1167\/iovs.09-4798","article-title":"Age-related differences in the elasticity of the human cornea","volume":"52","author":"Knox Cartwright","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib117","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1097\/ICO.0000000000002092","article-title":"Accelerated versus standard corneal cross-linking for progressive keratoconus: a meta-analysis of randomized controlled trials","volume":"39","author":"Kobashi","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib118","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/ICO.0000000000002129","article-title":"Correlation between corneal biomechanical indices and the severity of keratoconus","volume":"39","author":"Koh","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib119","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jcrs.2005.12.092","article-title":"Biomechanical evidence of the distribution of cross-links in corneas treated with riboflavin and ultraviolet A light","volume":"32","author":"Kohlhaas","year":"2006","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib120","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/ICO.0b013e3181915943","article-title":"Scheimpflug imaging of corneas after collagen cross-linking","volume":"28","author":"Koller","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib121","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1016\/j.jcrs.2009.03.035","article-title":"Complication and failure rates after corneal crosslinking","volume":"35","author":"Koller","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib122","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.jcrs.2011.03.041","article-title":"Flattening of the cornea after collagen crosslinking for keratoconus","volume":"37","author":"Koller","year":"2011","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib123","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jcrs.2012.01.024","article-title":"Refractive and topographic results of benzalkonium chloride-assisted transepithelial crosslinking","volume":"38","author":"Koppen","year":"2012","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib124","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ajo.2020.06.013","article-title":"Repeatability of the Pentacam HR in various grades of keratoconus","volume":"219","author":"Kreps","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib125","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/ICL.0000000000000095","article-title":"First proposed efficacy study of high versus standard irradiance and fractionated riboflavin\/ultraviolet a cross-linking with equivalent energy exposure","volume":"40","author":"Krueger","year":"2014","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.preteyeres.2024.101276_bib126","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ophtha.2005.10.009","article-title":"Is there an association between diabetes and keratoconus?","volume":"113","author":"Kuo","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib127","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.ajo.2007.11.017","article-title":"Changes in the quality-of-life of people with keratoconus","volume":"145","author":"Kymes","year":"2008","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib128","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.jcrs.2007.06.070","article-title":"Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal ectasia","volume":"33","author":"Kymionis","year":"2007","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib129","doi-asserted-by":"crossref","first-page":"S807","DOI":"10.3928\/1081597X-20090813-09","article-title":"Simultaneous topography-guided PRK followed by corneal collagen cross-linking for keratoconus","volume":"25","author":"Kymionis","year":"2009","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib130","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1016\/j.ophtha.2009.09.018","article-title":"Intraoperative pachymetric measurements during corneal collagen cross-linking with riboflavin and ultraviolet A irradiation","volume":"116","author":"Kymionis","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib131","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.jcrs.2007.06.036","article-title":"Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus","volume":"33","author":"Kymionis","year":"2007","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib132","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ajo.2011.05.036","article-title":"Corneal collagen cross-linking with riboflavin and ultraviolet-A irradiation in patients with thin corneas","volume":"153","author":"Kymionis","year":"2012","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib133","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3928\/1081597X-20160216-01","article-title":"Corneal stromal demarcation line depth following standard and a modified high intensity corneal cross-linking protocol","volume":"32","author":"Kymionis","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib134","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/1752-1947-5-152","article-title":"Corneal melting after collagen cross-linking for keratoconus: a case report","volume":"5","author":"Labiris","year":"2011","journal-title":"J. Med. Case Rep."},{"key":"10.1016\/j.preteyeres.2024.101276_bib135","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1007\/s00417-011-1674-0","article-title":"Biomechanical property analysis after corneal collagen cross-linking in relation to ultraviolet A irradiation time","volume":"249","author":"Lanchares","year":"2011","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib136","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/ICO.0000000000001878","article-title":"Comparative functional outcomes after corneal crosslinking using standard, accelerated, and accelerated with higher total fluence protocols","volume":"38","author":"Lang","year":"2019","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib137","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12886-015-0070-7","article-title":"Prospective, randomized, double-blind trial to investigate the efficacy and safety of corneal cross-linking to halt the progression of keratoconus","volume":"15","author":"Lang","year":"2015","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib138","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.ophtha.2021.04.019","article-title":"Effect of corneal cross-linking versus standard care on keratoconus progression in young patients: the KERALINK randomized controlled trial","volume":"128","author":"Larkin","year":"2021","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib139","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/ICO.0000000000002157","article-title":"Revisiting the safety of the corneal collagen crosslinking procedure: evaluation of the effect of ultraviolet A radiation on retinal function and structure","volume":"39","author":"Lazaridis","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib140","doi-asserted-by":"crossref","first-page":"942","DOI":"10.3928\/1081597X-20100212-09","article-title":"Transepithelial corneal collagen cross-linking in keratoconus","volume":"26","author":"Leccisotti","year":"2010","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib141","doi-asserted-by":"crossref","first-page":"816","DOI":"10.3928\/1081597X-20210830-01","article-title":"Risk factors for progression of keratoconus and failure rate after corneal cross-linking","volume":"37","author":"Lenk","year":"2021","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib142","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3928\/1081597X-20170413-01","article-title":"Increased hair cortisol concentrations in patients with progressive keratoconus","volume":"33","author":"Lenk","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib143","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.ophtha.2017.03.019","article-title":"Corneal collagen cross-linking in the management of keratoconus in Canada: a cost-effectiveness analysis","volume":"124","author":"Leung","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib144","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1167\/iovs.06-0214","article-title":"Two-stage genome-wide linkage scan in keratoconus sib pair families","volume":"47","author":"Li","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib145","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1080\/13696998.2020.1851556","article-title":"Corneal cross-linking versus conventional management for keratoconus: a lifetime economic model","volume":"24","author":"Lindstrom","year":"2021","journal-title":"J. Med. Econ."},{"key":"10.1016\/j.preteyeres.2024.101276_bib146","doi-asserted-by":"crossref","DOI":"10.1038\/s41433-023-02405-2","article-title":"Smoking, alcohol consumption and corneal biomechanical parameters among Chinese university students","author":"Liu","year":"2023","journal-title":"Eye"},{"key":"10.1016\/j.preteyeres.2024.101276_bib147","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jcrs.2004.10.044","article-title":"Determining in vivo biomechanical properties of the cornea with an ocular response analyzer","volume":"31","author":"Luce","year":"2005","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib148","first-page":"483","article-title":"Influence of cigarette smoke on cross-linking of dermal collagen","volume":"35","author":"Madhukumar","year":"1997","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib149","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00003226-200001000-00002","article-title":"Three decades of corneal transplantation: indications and patient characteristics","volume":"19","author":"Maeno","year":"2000","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib150","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1161\/01.HYP.0000047464.66901.60","article-title":"Effect of smoking on arterial stiffness and pulse pressure amplification","volume":"41","author":"Mahmud","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.preteyeres.2024.101276_bib151","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0925-4439(92)90041-K","article-title":"Ageing of the human corneal stroma: structural and biochemical changes","volume":"1138","author":"Malik","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.preteyeres.2024.101276_bib152","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1167\/tvst.9.6.4","article-title":"Decreased riboflavin impregnation time does not increase the risk for endothelial phototoxicity during corneal cross-linking","volume":"9","author":"Marcovich","year":"2020","journal-title":"Transl.Vis.Sci.Technol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib153","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3928\/1081597X-20200406-02","article-title":"Iontophoresis corneal cross-linking with enhanced fluence and pulsed UV-A light: 3-year clinical results","volume":"36","author":"Mazzotta","year":"2020","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib154","doi-asserted-by":"crossref","first-page":"438","DOI":"10.3928\/1081597X-20180515-02","article-title":"Enhanced-fluence pulsed-light iontophoresis corneal cross-linking: 1-year morphological and clinical results","volume":"34","author":"Mazzotta","year":"2018","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib155","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11175039","article-title":"Transepithelial enhanced fluence pulsed light M accelerated crosslinking for early progressive keratoconus with chemically enhanced riboflavin solutions and air room oxygen","volume":"11","author":"Mazzotta","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.preteyeres.2024.101276_bib156","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1442-9071.2007.01536.x","article-title":"Stromal haze after combined riboflavin-UVA corneal collagen cross-linking in keratoconus: in vivo confocal microscopic evaluation","volume":"35","author":"Mazzotta","year":"2007","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib157","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/ICO.0b013e318030df5a","article-title":"Treatment of progressive keratoconus by riboflavin-UVA-induced cross-linking of corneal collagen: ultrastructural analysis by Heidelberg Retinal Tomograph II in vivo confocal microscopy in humans","volume":"26","author":"Mazzotta","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib158","first-page":"8","article-title":"Pachymetry-based accelerated crosslinking: the \u201cM nomogram\u201d for standardized treatment of all-thickness progressive ectatic corneas","volume":"7","author":"Mazzotta","year":"2018","journal-title":"Int. J. Keratoconus Ectatic Corneal Dis."},{"key":"10.1016\/j.preteyeres.2024.101276_bib159","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1755-3768.2010.01890.x","article-title":"Morphological and functional correlations in riboflavin UV A corneal collagen cross-linking for keratoconus","volume":"90","author":"Mazzotta","year":"2012","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib160","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10061324","article-title":"Chemically-boosted corneal cross-linking for the treatment of keratoconus through a riboflavin 0.25% optimized solution with high superoxide anion release","volume":"10","author":"Mazzotta","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.preteyeres.2024.101276_bib161","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jtos.2015.04.007","article-title":"In vivo confocal microscopy after corneal collagen crosslinking","volume":"13","author":"Mazzotta","year":"2015","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.preteyeres.2024.101276_bib162","doi-asserted-by":"crossref","first-page":"326","DOI":"10.3928\/1081597X-20160225-04","article-title":"In vivo confocal microscopy after contact lens-assisted corneal collagen cross-linking for thin keratoconic corneas","volume":"32","author":"Mazzotta","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib163","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2031031","article-title":"Accelerated corneal collagen cross-linking using topography-guided UV-A energy emission: preliminary clinical and morphological outcomes","volume":"2016","author":"Mazzotta","year":"2016","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib164","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2023.1198246","article-title":"Progressive high-fluence epithelium-on accelerated corneal crosslinking: a novel corneal photodynamic therapy for early progressive keratoconus","volume":"10","author":"Mazzotta","year":"2023","journal-title":"Front. Med."},{"key":"10.1016\/j.preteyeres.2024.101276_bib165","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/17469899.2023.2207010","article-title":"Crosslinking for progressive keratoconus: is there room for improvement?","volume":"18","author":"Mazzotta","year":"2023","journal-title":"Expet Rev. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib166","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40662-021-00240-8","article-title":"Long term results of accelerated 9 mW corneal crosslinking for early progressive keratoconus: the Siena Eye-Cross Study 2","volume":"8","author":"Mazzotta","year":"2021","journal-title":"Eye Vis."},{"key":"10.1016\/j.preteyeres.2024.101276_bib167","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.2147\/OPTH.S66372","article-title":"Customized epithelial debridement for thin ectatic corneas undergoing corneal cross-linking: epithelial island cross-linking technique","volume":"8","author":"Mazzotta","year":"2014","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib168","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1097\/j.jcrs.0000000000000347","article-title":"Customized corneal crosslinking for treatment of progressive keratoconus: clinical and OCT outcomes using a transepithelial approach with supplemental oxygen","volume":"46","author":"Mazzotta","year":"2020","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib169","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/ICO.0000000000003380","article-title":"Ray-tracing transepithelial excimer laser central corneal remodeling plus pachymetry-guided accelerated corneal crosslinking for keratoconus","volume":"43","author":"Mazzotta","year":"2024","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib170","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/ICO.0000000000001505","article-title":"Corneal collagen cross-linking with riboflavin and ultraviolet A light for pediatric keratoconus: ten-year results","volume":"37","author":"Mazzotta","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib171","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ajo.2008.05.042","article-title":"Corneal healing after riboflavin ultraviolet-A collagen cross-linking determined by confocal laser scanning microscopy in vivo: early and late modifications","volume":"146","author":"Mazzotta","year":"2008","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib172","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1038\/eye.2014.163","article-title":"Pulsed vs continuous light accelerated corneal collagen crosslinking: in vivo qualitative investigation by confocal microscopy and corneal OCT","volume":"28","author":"Mazzotta","year":"2014","journal-title":"Eye"},{"issue":"Suppl. 2","key":"10.1016\/j.preteyeres.2024.101276_bib173","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1097\/ICL.0000000000000432","article-title":"Keratoconus progression in patients with allergy and elevated surface matrix metalloproteinase 9 point-of-care test","volume":"44","author":"Mazzotta","year":"2018","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.preteyeres.2024.101276_bib174","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/604731","article-title":"Pulsed light accelerated crosslinking versus continuous light accelerated crosslinking: one-year results","volume":"2014","author":"Mazzotta","year":"2014","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib175","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/17469899.2019.1611425","article-title":"The meaning of the demarcation line after riboflavin-UVA corneal collagen crosslinking","volume":"14","author":"Mazzotta","year":"2019","journal-title":"Expet Rev. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib176","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1167\/iovs.09-3738","article-title":"Mechanisms of corneal tissue cross-linking in response to treatment with topical riboflavin and long-wavelength ultraviolet radiation (UVA)","volume":"51","author":"McCall","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib177","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.clae.2007.07.008","article-title":"Management of chronic habits of abnormal eye rubbing","volume":"31","author":"McMonnies","year":"2008","journal-title":"Contact Lens Anterior Eye : J. Br. Contact Lens Assoc."},{"key":"10.1016\/j.preteyeres.2024.101276_bib178","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.clae.2008.11.001","article-title":"Behaviour modification in the management of chronic habits of abnormal eye rubbing","volume":"32","author":"McMonnies","year":"2009","journal-title":"Contact Lens Anterior Eye : J. Br. Contact Lens Assoc."},{"key":"10.1016\/j.preteyeres.2024.101276_bib179","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/ICO.0b013e318198384f","article-title":"Mechanisms of rubbing-related corneal trauma in keratoconus","volume":"28","author":"McMonnies","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib180","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1097\/ICO.0b013e3181ca36ea","article-title":"Keratectasia, rubbing, yoga, weightlifting, and intraocular pressure","volume":"29","author":"McMonnies","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib181","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1097\/OPX.0000000000000455","article-title":"Inflammation and keratoconus","volume":"92","author":"McMonnies","year":"2015","journal-title":"Optom. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib182","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e13206","article-title":"Analysis of riboflavin\/ultraviolet a corneal cross-linking by molecular spectroscopy","volume":"9","author":"Melcher","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.preteyeres.2024.101276_bib183","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jcrs.2007.03.021","article-title":"Riboflavin and ultraviolet A collagen crosslinking: in vivo thermographic analysis of the corneal surface","volume":"33","author":"Mencucci","year":"2007","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib184","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0002-9394(02)02278-X","article-title":"Assessment of visual function after corneal transplantation: the quality of life and psychometric assessment after corneal transplantation (Q-PACT) study","volume":"135","author":"Mendes","year":"2003","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jdermsci.2007.06.015","article-title":"Tobacco smoke causes premature skin aging","volume":"48","author":"Morita","year":"2007","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib186","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/bjo.85.4.437","article-title":"The specific architecture of the anterior stroma accounts for maintenance of corneal curvature","volume":"85","author":"Muller","year":"2001","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib187","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/jor.20077","article-title":"Hydrostatic pressure induces apoptosis of chondrocytes cultured in alginate beads","volume":"24","author":"Nakamura","year":"2006","journal-title":"J. Orthop. Res. : Off. Publ. Orthopaed. Res. Soc."},{"key":"10.1016\/j.preteyeres.2024.101276_bib188","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8285649","article-title":"10-Year results of standard cross-linking in patients with progressive keratoconus in Romania","volume":"2019","author":"Nicula","year":"2019","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib189","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1136\/bjophthalmol-2016-309210","article-title":"Refractive improvements and safety with topography-guided corneal crosslinking for keratoconus: 1-year results","volume":"101","author":"Nordstrom","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib190","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1136\/bjo.2010.196493","article-title":"A randomised, prospective study to investigate the efficacy of riboflavin\/ultraviolet A (370 nm) corneal collagen cross-linkage to halt the progression of keratoconus","volume":"95","author":"O'Brart","year":"2011","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib191","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.ajo.2015.08.023","article-title":"Corneal cross-linking to halt the progression of keratoconus and corneal ectasia: seven-year follow-up","volume":"160","author":"O'Brart","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib192","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.1167\/iovs.18-24795","article-title":"Author response: the role of riboflavin concentration and oxygen in the efficacy and depth of corneal crosslinking","volume":"59","author":"O'Brart","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib193","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1167\/iovs.17-22994","article-title":"An investigation of the effects of riboflavin concentration on the efficacy of corneal cross-linking using an enzymatic resistance model in porcine corneas","volume":"59","author":"O'Brart","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib194","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1177\/1120672120947664","article-title":"Extreme corneal flattening following collagen crosslinking for progressive keratoconus","volume":"31","author":"Padmanabhan","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"issue":"Pt 4","key":"10.1016\/j.preteyeres.2024.101276_bib195","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/eye.2000.154","article-title":"Does ethnic origin influence the incidence or severity of keratoconus?","volume":"14","author":"Pearson","year":"2000","journal-title":"Eye"},{"key":"10.1016\/j.preteyeres.2024.101276_bib196","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ajo.2019.05.025","article-title":"Large field of view corneal epithelium and Bowman's layer thickness maps in keratoconic and healthy eyes","volume":"209","author":"Pircher","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib197","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jcrs.2008.09.029","article-title":"Bacterial keratitis early after corneal crosslinking with riboflavin and ultraviolet-A","volume":"35","author":"Pollhammer","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib198","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1998","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib199","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000055492","article-title":"Altered organization of collagen in the apex of keratoconus corneas","volume":"30","author":"Radner","year":"1998","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib200","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jcrs.2007.12.039","article-title":"Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results","volume":"34","author":"Raiskup-Wolf","year":"2008","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib201","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-3-030-84506-3_6","article-title":"Accelerated crosslinking: the new epithelium-off","author":"Raiskup","year":"2022","journal-title":"Keratoconus"},{"key":"10.1016\/j.preteyeres.2024.101276_bib202","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ajo.2023.01.022","article-title":"Corneal crosslinking with riboflavin and UVA light in progressive keratoconus: fifteen-year results","volume":"250","author":"Raiskup","year":"2023","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib203","doi-asserted-by":"crossref","first-page":"S824","DOI":"10.3928\/1081597X-20090813-12","article-title":"Permanent corneal haze after riboflavin-UVA-induced cross-linking in keratoconus","volume":"25","author":"Raiskup","year":"2009","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib204","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1055\/s-0043-111797","article-title":"Keratokonus: heutige therapieoptionen","volume":"235","author":"Raiskup","year":"2018","journal-title":"Klin Monbl.Augenheilkd"},{"key":"10.1016\/j.preteyeres.2024.101276_bib205","doi-asserted-by":"crossref","first-page":"234","DOI":"10.3109\/02713683.2011.637656","article-title":"Riboflavin osmolar modification for transepithelial corneal cross-linking","volume":"37","author":"Raiskup","year":"2012","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib206","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ajo.2011.01.016","article-title":"Corneal cross-linking with hypo-osmolar riboflavin solution in thin keratoconic corneas","volume":"152","author":"Raiskup","year":"2011","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib207","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jcrs.2014.09.033","article-title":"Corneal collagen crosslinking with riboflavin and ultraviolet-A light in progressive keratoconus: ten-year results","volume":"41","author":"Raiskup","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib208","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.jcrs.2008.09.035","article-title":"Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use","volume":"35","author":"Rama","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib209","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3928\/1081597X-20170925-01","article-title":"Corneal cross-linking (CXL): standardizing terminology and protocol nomenclature","volume":"33","author":"Randleman","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib210","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.ajo.2010.10.034","article-title":"The lifetime economic burden of keratoconus: a decision analysis using a markov model","volume":"151","author":"Rebenitsch","year":"2011","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib211","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1097\/j.jcrs.0000000000000640","article-title":"Selective transepithelial ablation with simultaneous accelerated corneal crosslinking for corneal regularization of keratoconus: STARE-X protocol","volume":"47","author":"Rechichi","year":"2021","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib212","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.ajo.2005.05.029","article-title":"Risk factors for progression to penetrating keratoplasty in patients with keratoconus","volume":"140","author":"Reeves","year":"2005","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib213","first-page":"751","article-title":"Collagenolytic activity in keratoconus","volume":"14","author":"Rehany","year":"1982","journal-title":"Ann. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib214","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1001\/archopht.124.12.1754","article-title":"The economic burden of major adult visual disorders in the United States","volume":"124","author":"Rein","year":"2006","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib215","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/tvst.2.7.6","article-title":"The biomechanical effect of corneal collagen cross-linking (CXL) with riboflavin and UV-A is oxygen dependent","volume":"2","author":"Richoz","year":"2013","journal-title":"Transl.Vis.Sci.Technol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib216","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.jcrs.2014.04.019","article-title":"Concepts and misconceptions in corneal biomechanics","volume":"40","author":"Roberts","year":"2014","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib217","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2023.100373","article-title":"Corneal stress distribution evolves from thickness-driven in normal corneas to curvature-driven with progression in keratoconus","volume":"4","author":"Roberts","year":"2024","journal-title":"Ophthalmol.Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib218","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3928\/1081597X-20161221-03","article-title":"Introduction of two novel stiffness parameters and interpretation of air puff-induced biomechanical deformation parameters with a dynamic Scheimpflug analyzer","volume":"33","author":"Roberts","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib219","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3928\/1081597X-20130129-08","article-title":"SD-OCT analysis of regional epithelial thickness profiles in keratoconus, postoperative corneal ectasia, and normal eyes","volume":"29","author":"Rocha","year":"2013","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib220","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1111\/j.1755-3768.2010.02067.x","article-title":"No retinal morphology changes after use of riboflavin and long-wavelength ultraviolet light for treatment of keratoconus","volume":"90","author":"Romano","year":"2012","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib221","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/ICO.0000000000002492","article-title":"Comparative analysis of safety and efficacy of topography-guided customized cross-linking and standard cross-linking in the treatment of progressive keratoconus","volume":"40","author":"Sachdev","year":"2021","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib222","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4103\/IJO.IJO_762_23","article-title":"Long-term outcomes of tailored stromal expansion with refractive lenticule for crosslinking thin corneas","volume":"72","author":"Sachdev","year":"2024","journal-title":"Indian J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib223","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.jcrs.2015.04.007","article-title":"Tailored stromal expansion with a refractive lenticule for crosslinking the ultrathin cornea","volume":"41","author":"Sachdev","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib224","first-page":"67","article-title":"Accelerated versus conventional corneal collagen cross-linking in patients with keratoconus: an intrapatient comparative study","volume":"38","author":"Sadoughi","year":"2018","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib225","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1177\/11206721211052878","article-title":"Long-term visual, anterior and posterior corneal changes after crosslinking for progressive keratoconus","volume":"32","author":"Salman","year":"2022","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib226","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/glia.10342","article-title":"Responses and signaling pathways in human optic nerve head astrocytes exposed to hydrostatic pressure in vitro","volume":"45","author":"Salvador-Silva","year":"2004","journal-title":"Glia"},{"key":"10.1016\/j.preteyeres.2024.101276_bib227","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1097\/ICO.0000000000000460","article-title":"Does corneal collagen cross-linking reduce the need for keratoplasties in patients with keratoconus?","volume":"34","author":"Sandvik","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib228","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1001\/archopht.1989.01070020581044","article-title":"Lysosomal enzyme abnormalities in keratoconus","volume":"107","author":"Sawaguchi","year":"1989","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib229","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/ICO.0000000000002406","article-title":"Corneal crosslinking to regress pathologic corneal neovascularization before high-risk keratoplasty","volume":"40","author":"Schaub","year":"2021","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib230","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00347-007-1587-9","article-title":"[Enzymatic evidence of the depth dependence of stiffening on riboflavin\/UVA treated corneas]","volume":"105","author":"Schilde","year":"2008","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.preteyeres.2024.101276_bib231","doi-asserted-by":"crossref","first-page":"9048","DOI":"10.1167\/iovs.11-7818","article-title":"Equivalence of biomechanical changes induced by rapid and standard corneal cross-linking, using riboflavin and ultraviolet radiation","volume":"52","author":"Schumacher","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib232","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0161-6420(99)00015-9","article-title":"Increased intraocular pressure and visual field defects in high resistance wind instrument players","volume":"107","author":"Schuman","year":"2000","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib233","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1097\/ICO.0000000000001639","article-title":"Diagnostic ability of corneal shape and biomechanical parameters for detecting frank keratoconus","volume":"37","author":"Sedaghat","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib234","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3928\/1081597X-20181012-02","article-title":"Long-term evaluation of corneal biomechanical properties after corneal cross-linking for keratoconus: a 4-year longitudinal study","volume":"34","author":"Sedaghat","year":"2018","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib235","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/BF02181195","article-title":"Side effects in excimer corneal surgery. DNA damage as a result of 193 nm excimer laser radiation","volume":"226","author":"Seiler","year":"1988","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib236","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1097\/01.ico.0000225720.38748.58","article-title":"Corneal cross-linking-induced stromal demarcation line","volume":"25","author":"Seiler","year":"2006","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib237","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1007\/s004179900111","article-title":"Manifest diabetes and keratoconus: a retrospective case-control study","volume":"238","author":"Seiler","year":"2000","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib238","article-title":"Conservative therapy of keratoconus by enhancement of collagen cross-links","volume":"37","author":"Seiler","year":"1996","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib239","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1167\/iovs.19-26686","article-title":"Riboflavin concentrations at the endothelium during corneal cross-linking in humans","volume":"60","author":"Seiler","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib240","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ajo.2016.02.029","article-title":"Customized corneal cross-linking: one-year results","volume":"166","author":"Seiler","year":"2016","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib241","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ajo.2020.11.001","article-title":"Oxygen kinetics during corneal cross-linking with and without supplementary oxygen","volume":"223","author":"Seiler","year":"2021","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib242","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3928\/1081597X-20220114-02","article-title":"Repeatability and comparison of corneal tomography in mild to severe keratoconus between the anterior segment OCT MS-39 and Pentacam HR","volume":"38","author":"Seiler","year":"2022","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib243","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ajo.2019.02.010","article-title":"Brillouin spectroscopy of normal and keratoconus corneas","volume":"202","author":"Seiler","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib244","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1179\/1351000213Y.0000000076","article-title":"UVA irradiation of riboflavin generates oxygen-dependent hydroxyl radicals","volume":"19","author":"Sel","year":"2014","journal-title":"Redox Rep."},{"key":"10.1016\/j.preteyeres.2024.101276_bib245","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1111\/aos.13814","article-title":"Comparison of standard and accelerated corneal cross-linking for the treatment of keratoconus: a meta-analysis","volume":"97","author":"Shajari","year":"2019","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib246","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3928\/1081597X-20170621-07","article-title":"Customized corneal cross-linking using different UVA beam profiles","volume":"33","author":"Shetty","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib247","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ajo.2015.05.019","article-title":"Current protocols of corneal collagen cross-linking: visual, refractive, and tomographic outcomes","volume":"160","author":"Shetty","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib248","doi-asserted-by":"crossref","first-page":"707","DOI":"10.3928\/1081597X-20200729-01","article-title":"A simple calculator to decide UVA \"on\" time for cross-linking of thin keratoconic corneas (< 400 microm)","volume":"36","author":"Shetty","year":"2020","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib249","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1364\/AO.44.002162","article-title":"Adjustment of guidelines for exposure of the eye to optical radiation from ocular instruments: statement from a task group of the International Commission on Non-Ionizing Radiation Protection (ICNIRP)","volume":"44","author":"Sliney","year":"2005","journal-title":"Appl. Opt."},{"key":"10.1016\/j.preteyeres.2024.101276_bib250","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.jcrs.2013.01.045","article-title":"Effective corneal collagen crosslinking in advanced cases of progressive keratoconus","volume":"39","author":"Sloot","year":"2013","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib251","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.ajo.2015.02.005","article-title":"Transepithelial versus epithelium-off corneal cross-linking for the treatment of progressive keratoconus: a randomized controlled trial","volume":"159","author":"Soeters","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib252","doi-asserted-by":"crossref","first-page":"5059","DOI":"10.1167\/iovs.12-10710","article-title":"Corneal resistance to shear force after UVA-riboflavin cross-linking","volume":"54","author":"Sondergaard","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib253","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1167\/iovs.12-10346","article-title":"Reduction of stromal swelling pressure after UVA-riboflavin cross-linking","volume":"54","author":"Sondergaard","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib254","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jcrs.2018.02.017","article-title":"Corneal stromal demarcation line after 4 protocols of corneal crosslinking in keratoconus determined with anterior segment optical coherence tomography","volume":"44","author":"Spadea","year":"2018","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib255","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2174\/1874364101105010014","article-title":"Corneal cross-linking and safety issues","volume":"5","author":"Spoerl","year":"2011","journal-title":"Open Ophthalmol. J."},{"key":"10.1016\/j.preteyeres.2024.101276_bib256","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/exer.1997.0410","article-title":"Induction of cross-links in corneal tissue","volume":"66","author":"Spoerl","year":"1998","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib257","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/ICO.0b013e3180334f78","article-title":"Safety of UVA-riboflavin cross-linking of the cornea","volume":"26","author":"Spoerl","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib258","doi-asserted-by":"crossref","first-page":"S737","DOI":"10.3928\/1081597X-20080901-18","article-title":"Cigarette smoking is negatively associated with keratoconus","volume":"24","author":"Spoerl","year":"2008","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib259","first-page":"711","article-title":"Techniques for stiffening the cornea","volume":"15","author":"Spoerl","year":"1999","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib260","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3928\/1081597X-20110106-01","article-title":"Detection of biomechanical changes after corneal cross-linking using Ocular Response Analyzer software","volume":"27","author":"Spoerl","year":"2011","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib261","first-page":"136","article-title":"Thermomechanical behavior of collagen-cross-linked porcine cornea. Ophthalmologica. Journal international d'ophtalmologie","volume":"218","author":"Spoerl","year":"2004","journal-title":"Int. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib262","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1159\/000076884","article-title":"Cross-linking of human amniotic membrane by glutaraldehyde","volume":"36","author":"Spoerl","year":"2004","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib263","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/02713680490513182","article-title":"Increased resistance of crosslinked cornea against enzymatic digestion","volume":"29","author":"Spoerl","year":"2004","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib264","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1136\/bjo.2007.124388","article-title":"Oestrogen-induced changes in biomechanics in the cornea as a possible reason for keratectasia","volume":"91","author":"Spoerl","year":"2007","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib265","doi-asserted-by":"crossref","first-page":"S794","DOI":"10.3928\/1081597X-20090813-06","article-title":"Influence of high-dose cortisol on the biomechanics of incubated porcine corneal strips","volume":"25","author":"Spoerl","year":"2009","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib266","first-page":"902","article-title":"[Increased rigidity of the cornea caused by intrastromal cross-linking]","volume":"94","author":"Sporl","year":"1997","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.preteyeres.2024.101276_bib267","first-page":"131","article-title":"[Biophysical principles of collagen cross-linking]","volume":"225","author":"Sporl","year":"2008","journal-title":"Klin Monbl.Augenheilkd"},{"key":"10.1016\/j.preteyeres.2024.101276_bib268","first-page":"203","article-title":"[Studies on the stabilization of the cornea in rabbits]","volume":"97","author":"Sporl","year":"2000","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.preteyeres.2024.101276_bib269","doi-asserted-by":"crossref","DOI":"10.1002\/ca.23728","article-title":"Morphological alterations of the cornea following crosslinking treatment (CXL)","author":"Subasinghe","year":"2021","journal-title":"Clin. Anat."},{"key":"10.1016\/j.preteyeres.2024.101276_bib270","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3928\/1081597X-20161006-02","article-title":"Repeated cross-linking after a short time does not provide any additional biomechanical stiffness in the mouse cornea in vivo","volume":"33","author":"Tabibian","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib271","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3109\/02713683.2012.669007","article-title":"Identification of biomechanical properties of the cornea: the ocular response analyzer","volume":"37","author":"Terai","year":"2012","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib272","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/bjophthalmol-2011-300244","article-title":"Changing trends in keratoplasty in the West of Scotland: a 10-year review","volume":"96","author":"Ting","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib273","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.jcrs.2017.05.036","article-title":"Efficacy of different accelerated corneal crosslinking protocols for progressive keratoconus","volume":"43","author":"Toker","year":"2017","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib274","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3928\/1081597X-20220715-03","article-title":"The impact of repetitive and prolonged eye rubbing on corneal biomechanics","volume":"38","author":"Torres-Netto","year":"2022","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib275","doi-asserted-by":"crossref","first-page":"768","DOI":"10.3928\/1081597X-20180830-01","article-title":"Oxygen diffusion may limit the biomechanical effectiveness of iontophoresis-assisted transepithelial corneal cross-linking","volume":"34","author":"Torres-Netto","year":"2018","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib276","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3928\/1081597X-20121016-01","article-title":"Corneal confocal microscopy following conventional, transepithelial, and accelerated corneal collagen cross-linking procedures for keratoconus","volume":"28","author":"Touboul","year":"2012","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib277","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1006\/bbrc.1998.8955","article-title":"Altered posttranslational modifications of collagen in keloid","volume":"249","author":"Uzawa","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.preteyeres.2024.101276_bib278","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ajo.2019.01.015","article-title":"Corneal epithelial thickness intrasubject repeatability and its relation with visual limitation in keratoconus","volume":"200","author":"Vega-Estrada","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib279","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1097\/ICO.0b013e3182498902","article-title":"The effect of riboflavin-UV-A treatment on corneal limbal epithelial cells--a study on human cadaver eyes","volume":"31","author":"Vimalin","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib280","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ophtha.2008.09.048","article-title":"Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking","volume":"116","author":"Vinciguerra","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib281","doi-asserted-by":"crossref","first-page":"2519 e2511","DOI":"10.1016\/j.ophtha.2011.07.055","article-title":"Corneal crosslinking and lens opacity","volume":"118","author":"Vinciguerra","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib282","doi-asserted-by":"crossref","DOI":"10.1007\/s10792-021-01713-4","article-title":"New perspectives in keratoconus treatment: an update on iontophoresis-assisted corneal collagen crosslinking","author":"Vinciguerra","year":"2021","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib283","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3928\/1081597X-20160629-01","article-title":"Detection of keratoconus with a new biomechanical index","volume":"32","author":"Vinciguerra","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib284","doi-asserted-by":"crossref","first-page":"550","DOI":"10.3928\/1081597X-20160524-01","article-title":"Influence of pachymetry and intraocular pressure on dynamic corneal response parameters in healthy patients","volume":"32","author":"Vinciguerra","year":"2016","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib285","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11030678","article-title":"Transepithelial iontophoresis-assisted cross linking for progressive keratoconus: up to 7 Years of follow up","volume":"11","author":"Vinciguerra","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.preteyeres.2024.101276_bib286","doi-asserted-by":"crossref","first-page":"838","DOI":"10.3928\/1081597X-20201021-01","article-title":"Corneal cross-linking for progressive keratoconus: up to 13 Years of follow-up","volume":"36","author":"Vinciguerra","year":"2020","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib287","doi-asserted-by":"crossref","first-page":"840","DOI":"10.3928\/1081597X-20170922-02","article-title":"In vivo early corneal biomechanical changes after corneal cross-linking in patients with progressive keratoconus","volume":"33","author":"Vinciguerra","year":"2017","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib288","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.clae.2007.03.001","article-title":"Collaborative longitudinal evaluation of keratoconus (CLEK) study: methods and findings to date","volume":"30","author":"Wagner","year":"2007","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.preteyeres.2024.101276_bib289","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1002\/jbm.820291108","article-title":"Physical crosslinking of collagen fibers: comparison of ultraviolet irradiation and dehydrothermal treatment","volume":"29","author":"Weadock","year":"1995","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib290","doi-asserted-by":"crossref","first-page":"3920","DOI":"10.1167\/iovs.18-24656","article-title":"Comparison of standard versus accelerated corneal collagen cross-linking for keratoconus: a meta-analysis","volume":"59","author":"Wen","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib291","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1167\/iovs.12-11409","article-title":"The efficacy of corneal cross-linking shows a sudden decrease with very high intensity UV light and short treatment time","volume":"54","author":"Wernli","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib292","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s13063-024-08011-1","article-title":"UV light-mediated corneal crosslinking as (lymph)angioregressive pretreatment to promote graft survival after subsequent high-risk corneal transplantation (CrossCornealVision): protocol for a multicenter, randomized controlled trial","volume":"25","author":"Wiedemann","year":"2024","journal-title":"Trials"},{"key":"10.1016\/j.preteyeres.2024.101276_bib293","doi-asserted-by":"crossref","first-page":"8818","DOI":"10.1167\/iovs.11-8070","article-title":"Nonlinear optical macroscopic assessment of 3-D corneal collagen organization and axial biomechanics","volume":"52","author":"Winkler","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib294","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.ophtha.2013.10.028","article-title":"A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results","volume":"121","author":"Wittig-Silva","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib295","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.ophtha.2013.10.028","article-title":"A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results","volume":"121","author":"Wittig-Silva","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2024.101276_bib296","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3928\/1081597X-20130410-02","article-title":"Localized changes in stromal reflectivity after corneal collagen cross-linking observed with different imaging techniques","volume":"29","author":"Wittig-Silva","year":"2013","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib297","first-page":"S720","article-title":"A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results","volume":"24","author":"Wittig-Silva","year":"2008","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib298","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.jcrs.2008.11.036","article-title":"Biomechanical and histological changes after corneal crosslinking with and without epithelial debridement","volume":"35","author":"Wollensak","year":"2009","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib299","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/sj.eye.6700751","article-title":"Keratocyte cytotoxicity of riboflavin\/UVA-treatment in vitro","volume":"18","author":"Wollensak","year":"2004","journal-title":"Eye"},{"key":"10.1016\/j.preteyeres.2024.101276_bib300","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","article-title":"Riboflavin\/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus","volume":"135","author":"Wollensak","year":"2003","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib301","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/S0886-3350(03)00407-3","article-title":"Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking","volume":"29","author":"Wollensak","year":"2003","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib302","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/S0886-3350(03)00343-2","article-title":"Endothelial cell damage after riboflavin-ultraviolet-A treatment in the rabbit","volume":"29","author":"Wollensak","year":"2003","journal-title":"J. Cataract Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib303","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00003226-200401000-00008","article-title":"Keratocyte apoptosis after corneal collagen cross-linking using riboflavin\/UVA treatment","volume":"23","author":"Wollensak","year":"2004","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib304","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1177\/1120672118801130","article-title":"Biomechanical efficacy of corneal cross-linking using hypoosmolar riboflavin solution","volume":"29","author":"Wollensak","year":"2019","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib305","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1136\/bjo.2010.190843","article-title":"Interlamellar cohesion after corneal crosslinking using riboflavin and ultraviolet A light","volume":"95","author":"Wollensak","year":"2011","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib306","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1159\/000074071","article-title":"Corneal endothelial cytotoxicity of riboflavin\/UVA treatment in vitro","volume":"35","author":"Wollensak","year":"2003","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib307","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/01.ico.0000105827.85025.7f","article-title":"Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin\/UVA","volume":"23","author":"Wollensak","year":"2004","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib308","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.survophthal.2006.06.009","article-title":"Photochemical damage of the retina","volume":"51","author":"Wu","year":"2006","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2024.101276_bib309","first-page":"2537","article-title":"Baseline findings in the collaborative longitudinal evaluation of keratoconus (CLEK) study","volume":"39","author":"Zadnik","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib310","series-title":"Keratoconus: Current and Future State-Of-The-Art","first-page":"233","article-title":"Donor-recipient crosslinking-assisted manual deep anterior lamellar keratoplasty: drxl-dalk","author":"Zagari","year":"2022"},{"key":"10.1016\/j.preteyeres.2024.101276_bib311","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1097\/ICO.0b013e31818d381a","article-title":"Polymicrobial keratitis after a collagen cross-linking procedure with postoperative use of a contact lens: a case report","volume":"28","author":"Zamora","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.preteyeres.2024.101276_bib312","doi-asserted-by":"crossref","first-page":"721","DOI":"10.3928\/1081597X-20191004-01","article-title":"Depth-dependent reduction of biomechanical efficacy of contact lens-assisted corneal cross-linking analyzed by Brillouin microscopy","volume":"35","author":"Zhang","year":"2019","journal-title":"J. Refract. Surg."},{"key":"10.1016\/j.preteyeres.2024.101276_bib313","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1080\/02713683.2021.1904510","article-title":"Effects of mechanical compression on cell morphology and function in human corneal fibroblasts","volume":"46","author":"Zhang","year":"2021","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib314","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.109363","article-title":"Corneal biomechanical stiffness and histopathological changes after in vivo repeated accelerated corneal cross-linking in cat eyes","volume":"227","author":"Zhang","year":"2023","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2024.101276_bib315","doi-asserted-by":"crossref","first-page":"13011","DOI":"10.1074\/jbc.M110.169813","article-title":"Effects of ultraviolet-A and riboflavin on the interaction of collagen and proteoglycans during corneal cross-linking","volume":"286","author":"Zhang","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2024.101276_bib316","first-page":"1117","article-title":"Expression of degradative enzymes and protease inhibitors in corneas with keratoconus","volume":"39","author":"Zhou","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2024.101276_bib317","first-page":"127","article-title":"Peripheral cornea crosslinking before deep anterior lamellar keratoplasty","volume":"9","author":"Ziaei","year":"2020","journal-title":"Med. Hypothesis, Discov. Innovation (MEHDI) Ophthalmol."}],"container-title":["Progress in Retinal and Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350946224000417?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350946224000417?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T22:40:29Z","timestamp":1732142429000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1350946224000417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":317,"alternative-id":["S1350946224000417"],"URL":"https:\/\/doi.org\/10.1016\/j.preteyeres.2024.101276","relation":{},"ISSN":["1350-9462"],"issn-type":[{"value":"1350-9462","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice \u2013 Developments over 25 years","name":"articletitle","label":"Article Title"},{"value":"Progress in Retinal and Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preteyeres.2024.101276","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101276"}}