{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:35:45Z","timestamp":1793054145644,"version":"4.5.0"},"reference-count":276,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002924","name":"The Glaucoma Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019001","name":"National Taiwan University Center for Artificial Intelligence and Advanced Robotics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Retinal and Eye Research"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.preteyeres.2026.101490","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:30:23Z","timestamp":1783035023000},"page":"101490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Transcending genome-wide association studies to create useful multi-omic views of glaucoma"],"prefix":"10.1016","volume":"113","author":[{"given":"Keva","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hee","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony P.","family":"Khawaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Jardines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00eblle E.","family":"Vergroesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wishal D.","family":"Ramdas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey V.","family":"Stuart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N.","family":"Luben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pirro G.","family":"Hysi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Hanyuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana A.","family":"Zeleznik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayellet V.","family":"Segr\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeru Amrita","family":"Vallabh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya Yuan Rachel","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janey L.","family":"Wiggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5835-3496","authenticated-orcid":false,"given":"Louis R.","family":"Pasquale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.preteyeres.2026.101490_bib1","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1093\/brain\/awaf144","article-title":"Markers of axonal injury in blood and tissue triggered by acute and chronic demyelination","volume":"148","author":"Abdelhak","year":"2025","journal-title":"Brain"},{"key":"10.1016\/j.preteyeres.2026.101490_bib2","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1021\/acs.jproteome.8b00244","article-title":"Proteomic analysis of aqueous humor from primary open angle glaucoma patients on drug treatment revealed altered complement activation Cascade","volume":"17","author":"Adav","year":"2018","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib3","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1080\/14737159.2021.1941879","article-title":"Human tear fluid analysis for clinical applications: progress and prospects","volume":"21","author":"Adigal","year":"2021","journal-title":"Expert Rev. Mol. Diagn."},{"key":"10.1016\/j.preteyeres.2026.101490_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201700394","article-title":"The human eye proteome Project: updates on an emerging proteome","volume":"18","author":"Ahmad","year":"2018","journal-title":"Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib5","first-page":"143","article-title":"Helicobacter pylori eradication in the management of glaucoma","volume":"11","author":"Ala","year":"2020","journal-title":"Caspian J Intern Med"},{"key":"10.1016\/j.preteyeres.2026.101490_bib6","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.neuron.2017.04.022","article-title":"The dynamic epigenetic landscape of the retina during development, reprogramming, and tumorigenesis","volume":"94","author":"Aldiri","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.preteyeres.2026.101490_bib7","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.2147\/OPTH.S484855","article-title":"Impact of environmental factors on glaucoma progression: a systematic review","volume":"18","author":"Almarzouki","year":"2024","journal-title":"OPTH"},{"key":"10.1016\/j.preteyeres.2026.101490_bib8","doi-asserted-by":"crossref","first-page":"7486","DOI":"10.1167\/iovs.14-14792","article-title":"Acetylation preserves retinal ganglion cell structure and function in a chronic model of ocular hypertension","volume":"55","author":"Alsarraf","year":"2014","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib9","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.1039\/c2cs15331a","article-title":"Mass spectrometry-based proteomics: existing capabilities and future directions","volume":"41","author":"Angel","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.preteyeres.2026.101490_bib10","doi-asserted-by":"crossref","first-page":"2938","DOI":"10.3390\/jcm11102938","article-title":"Do oral pathogens inhabit the eye and play a role in ocular diseases?","volume":"11","author":"Arjunan","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0104416","article-title":"Oral microbiome link to neurodegeneration in glaucoma","volume":"9","author":"Astafurov","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2026.101490_bib12","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/ng.3875","article-title":"Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci","volume":"49","author":"Aung","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib13","first-page":"7132","article-title":"Tear nanoDSF denaturation profile is predictive of glaucoma","volume":"24","author":"Baksheeva","year":"2023","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13059-020-02252-4","article-title":"Exploiting the GTEx resources to decipher the mechanisms at GWAS loci","volume":"22","author":"Barbeira","year":"2021","journal-title":"Genome Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108268","article-title":"Metabolomic profiling of aqueous humor from glaucoma patients - the metabolomics in surgical ophthalmological patients (MISO) study","volume":"201","author":"Barbosa Breda","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib16","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1093\/brain\/awaf018","article-title":"Mendelian randomization identifies proteins involved in neurodegenerative diseases","volume":"148","author":"Belbasis","year":"2025","journal-title":"Brain"},{"key":"10.1016\/j.preteyeres.2026.101490_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046910","article-title":"Serum and antibodies of glaucoma patients lead to changes in the proteome, especially cell regulatory proteins, in retinal cells","volume":"7","author":"Bell","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2026.101490_bib18","article-title":"Oxidative and anti-oxidative stress markers in chronic glaucoma: a systematic review and meta-analysis","volume":"11","author":"Benoist d'Azy","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2026.101490_bib19","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s42003-025-07515-z","article-title":"A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research","volume":"8","author":"Beusch","year":"2025","journal-title":"Commun. Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2024.1397461","article-title":"Advances in aqueous humor proteomics for biomarker discovery and disease mechanisms exploration: a spotlight on primary open angle glaucoma","volume":"17","author":"Beutgen","year":"2024","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib21","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1167\/iovs.09-3903","article-title":"Valproic acid\u2013mediated neuroprotection and regeneration in injured retinal ganglion cells","volume":"51","author":"Biermann","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib22","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s13059-017-1156-8","article-title":"Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types","volume":"18","year":"2017","journal-title":"Genome Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib23","doi-asserted-by":"crossref","first-page":"8287","DOI":"10.1167\/iovs.11-8218","article-title":"Quantitative proteomics: TGF\u03b22 signaling in trabecular meshwork cells","volume":"52","author":"Bollinger","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib24","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.exer.2010.11.004","article-title":"Identification of differentially expressed proteins in the aqueous humor of primary congenital glaucoma","volume":"92","author":"Bouhenni","year":"2011","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib25","first-page":"1559","article-title":"Sources of variance in human tear proteomic samples: statistical evaluation, quality control, normalization, and biological Insight","volume":"25","author":"Bruszel","year":"2024","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib26","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1021\/acs.jproteome.8b00915","article-title":"Metabolomic profiling of aqueous humor in glaucoma points to taurine and spermine deficiency: findings from the Eye-D Study","volume":"18","author":"Buisset","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib27","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/ng.824","article-title":"Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1","volume":"43","author":"Burdon","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib28","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/j.ophtha.2012.02.004","article-title":"Glaucoma risk alleles at CDKN2B-AS1 are associated with lower intraocular pressure, normal-tension glaucoma, and advanced glaucoma","volume":"119","author":"Burdon","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib29","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/13816810.2017.1413659","article-title":"DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma","volume":"39","author":"Burdon","year":"2018","journal-title":"Ophthalmic Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib30","doi-asserted-by":"crossref","first-page":"e768","DOI":"10.1111\/aos.14374","article-title":"Tear and aqueous humour cytokine profile in primary open-angle glaucoma","volume":"98","author":"Burgos-Blasco","year":"2020","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib31","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","article-title":"The UK Biobank resource with deep phenotyping and genomic data","volume":"562","author":"Bycroft","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2026.101490_bib32","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/IJG.0000000000000603","article-title":"Changes in the lipidomic profile of aqueous humor in open-angle glaucoma","volume":"26","author":"Cabrerizo","year":"2017","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.preteyeres.2026.101490_bib33","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1038\/s41588-025-02319-7","article-title":"A standardized framework for circulating blood proteomics","volume":"57","author":"Cai","year":"2025","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-13573-8","article-title":"Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-\u03b22","volume":"12","author":"Callaghan","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib35","first-page":"107","article-title":"SomaScan bioinformatics: normalization, quality control, and assessment of pre-analytical variation","volume":"2929","author":"Candia","year":"2025"},{"key":"10.1016\/j.preteyeres.2026.101490_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-0716-2265-0_1","article-title":"Mass spectrometry-based proteomics for biomarker discovery","volume":"2486","author":"Cao","year":"2022","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib37","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1556\/030.66.2019.038","article-title":"Microbial dysbiosis and microbiota\u2013gut\u2013retina axis: the lesson from brain neurodegenerative diseases to primary open-angle glaucoma pathogenesis of autoimmunity","volume":"66","author":"Chaiwiang","year":"2019","journal-title":"Acta Microbiol. Immunol. Hung."},{"key":"10.1016\/j.preteyeres.2026.101490_bib38","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1167\/iovs.63.9.32","article-title":"Topical Glaucoma therapy is associated with alterations of the ocular surface microbiome","volume":"63","author":"Chang","year":"2022","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib39","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/15265161.2023.2276161","article-title":"Consideration and Disclosure of Group risks in genomics and other data-centric research: does the common rule need revision?","volume":"25","author":"Chapman","year":"2025","journal-title":"Am. J. Bioeth."},{"key":"10.1016\/j.preteyeres.2026.101490_bib40","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1167\/iovs.18-25802","article-title":"Optic nerve lipidomics reveal impaired glucosylsphingosine lipids pathway in glaucoma","volume":"60","author":"Chauhan","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib41","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1038\/s41467-018-05681-9","article-title":"Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma","volume":"9","author":"Chen","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib42","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/j.ajpath.2023.06.015","article-title":"The role of Gut Microbiota in glaucoma progression and other retinal diseases","volume":"193","author":"Chen","year":"2023","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib43","article-title":"The role of microglia in glaucoma - trigger and potential target","volume":"16","author":"Chen","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib44","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1038\/ng.3078","article-title":"Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma","volume":"46","author":"Chen","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib45","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1167\/iovs.14-16269","article-title":"Genetic variants associated with different risks for high tension glaucoma and normal tension glaucoma in a Chinese population","volume":"56","author":"Chen","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib46","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.4155\/bio-2020-0198","article-title":"Accelerating protein biomarker discovery and translation from proteomics research for clinical utility","volume":"12","author":"Chen","year":"2020","journal-title":"Bioanalysis"},{"key":"10.1016\/j.preteyeres.2026.101490_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2024.109887","article-title":"Aqueous humour protein dysregulation in Asian eyes with primary open angle glaucoma","volume":"243","author":"Choy","year":"2024","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib48","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.3390\/ijms26062470","article-title":"Short-Chain fatty acids and the gut\u2013retina connection: a systematic review","volume":"26","author":"Ciurariu","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib49","first-page":"2041","article-title":"Tear sampling and biomarker discovery: a robust workflow for routine clinical applications using UHPLC-MS\/MS and schirmer strips","volume":"26","author":"Comito","year":"2025","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib50","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/ng.3482","article-title":"Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open angle glaucoma","volume":"48","author":"Cooke Bailey","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib51","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41588-019-0556-y","article-title":"Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression","volume":"52","author":"Craig","year":"2020","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib52","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1146\/annurev-biodatasci-102523-103640","article-title":"Spatially resolved single-cell omics: methods, challenges, and future perspectives","volume":"7","author":"Dezem","year":"2024","journal-title":"Annu. Rev. Biomed. Data Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib53","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.exer.2018.10.006","article-title":"Investigation of the global protein content from healthy human tears","volume":"179","author":"Dor","year":"2019","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib54","doi-asserted-by":"crossref","first-page":"894","DOI":"10.3390\/microorganisms8060894","article-title":"Association between active Helicobacter pylori infection and glaucoma: a systematic review and meta-analysis","volume":"8","author":"Doulberis","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.preteyeres.2026.101490_bib55","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.3390\/cells13121060","article-title":"The TGF\u03b2 induced MicroRNAome of the trabecular meshwork","volume":"13","author":"Doyle","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.preteyeres.2026.101490_bib56","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1093\/hmg\/ddy040","article-title":"Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma","volume":"27","author":"Drewry","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib57","article-title":"Multi-omics integration predicts 17 disease incidences in the UK Biobank","author":"Du","year":"2025","journal-title":"Preprint. medRxiv"},{"key":"10.1016\/j.preteyeres.2026.101490_bib58","first-page":"2839","article-title":"Proteomic analysis of aqueous humor from patients with primary open angle glaucoma","volume":"16","author":"Duan","year":"2010","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2026.101490_bib59","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/s41586-023-06563-x","article-title":"Large-scale plasma proteomics comparisons through genetics and disease associations","volume":"622","author":"Eldjarn","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2026.101490_bib60","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1038\/nn.4030","article-title":"Host microbiota constantly control maturation and function of microglia in the CNS","volume":"18","author":"Erny","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib61","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1186\/s12886-023-03111-z","article-title":"Association between helicobacter pylori infection and primary open-angle glaucoma: a systematic review and meta-analysis","volume":"23","author":"Ezzati Amini","year":"2023","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib62","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1001\/jamaophthalmol.2019.3109","article-title":"Association of a primary open-angle glaucoma genetic risk Score with earlier Age at diagnosis","volume":"137","author":"Fan","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.preteyeres.2026.101490_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115633","article-title":"Role of epigenetic regulation in glaucoma","volume":"168","author":"Feng","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.preteyeres.2026.101490_bib64","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13099-017-0208-7","article-title":"A human stool-derived Bilophila wadsworthia strain caused systemic inflammation in specific-pathogen-free mice","volume":"9","author":"Feng","year":"2017","journal-title":"Gut Pathog."},{"key":"10.1016\/j.preteyeres.2026.101490_bib65","doi-asserted-by":"crossref","first-page":"e1221","DOI":"10.1016\/S2214-109X(17)30393-5","article-title":"Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis","volume":"5","author":"Flaxman","year":"2017","journal-title":"Lancet Global Health"},{"key":"10.1016\/j.preteyeres.2026.101490_bib66","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1093\/hmg\/11.11.1333","article-title":"Protein localization in the human eye and genetic screen of opticin","volume":"11","author":"Friedman","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib67","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/14789450.2017.1298448","article-title":"The potential impact of recent insights into proteomic changes associated with glaucoma","volume":"14","author":"Funke","year":"2017","journal-title":"Expert Rev. Proteonomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib68","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/s41588-018-0154-4","article-title":"Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation","volume":"50","author":"Gamazon","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib69","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/5712341","article-title":"Epigenetics and signaling pathways in glaucoma","volume":"2017","author":"Gauthier","year":"2017","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.preteyeres.2026.101490_bib70","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/s41467-020-20851-4","article-title":"Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries","volume":"12","author":"Gharahkhani","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib71","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/hdy.2010.54","article-title":"Epigenetics and gene expression","volume":"105","author":"Gibney","year":"2010","journal-title":"Heredity"},{"key":"10.1016\/j.preteyeres.2026.101490_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2025.101338","article-title":"A comprehensive scoping review of methodological approaches and clinical applications of tear fluid biomarkers","volume":"106","author":"Gijs","year":"2025","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.107921","article-title":"Gut microbiota compositional profile and serum metabolic phenotype in patients with primary open-angle glaucoma","volume":"191","author":"Gong","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2023.109592","article-title":"Untargeted metabolomics in the aqueous humor reveals the involvement of TAAR pathway in glaucoma","volume":"234","author":"Gowtham","year":"2023","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib75","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-7057-5_1","article-title":"Direct assessment of Plasma\/Serum sample quality for proteomics biomarker investigation","volume":"1619","author":"Greco","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108349","article-title":"Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation","volume":"201","author":"Greene","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib77","first-page":"1437","article-title":"Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma","volume":"14","author":"Grus","year":"2008","journal-title":"Mol. Vis."},{"key":"10.1016\/j.preteyeres.2026.101490_bib78","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/s41586-025-08584-0","article-title":"Mass-spectrometry-based proteomics: from single cells to clinical applications","volume":"638","author":"Guo","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2026.101490_bib79","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/s41467-023-44380-y","article-title":"Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma","volume":"15","author":"Hamel","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib80","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.ajhg.2021.05.005","article-title":"Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA","volume":"108","author":"Han","year":"2021","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib81","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/s41588-023-01428-5","article-title":"Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci","volume":"55","author":"Han","year":"2023","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib82","article-title":"Machine learning on prediagnostic metabolite data identifies etiologic endotypes of exfoliation glaucoma in United States health professionals","volume":"5","author":"Hanyuda","year":"2024","journal-title":"Ophthalmol Sci"},{"key":"10.1016\/j.preteyeres.2026.101490_bib83","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.3390\/nu17213369","article-title":"Diet, exercise, and lifestyle in glaucoma: current evidence and future perspectives","volume":"17","author":"Hanyuda","year":"2025","journal-title":"Nutrients"},{"key":"10.1016\/j.preteyeres.2026.101490_bib84","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1093\/hmg\/ddv347","article-title":"Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus","volume":"24","author":"Hauser","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib85","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1001\/jama.2019.16161","article-title":"Association of genetic variants with primary open-angle glaucoma among individuals with African ancestry","volume":"322","author":"Hauser","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.preteyeres.2026.101490_bib86","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/s10038-020-0736-8","article-title":"Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma","volume":"65","author":"Hayat","year":"2020","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib87","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1002\/pmic.201300377","article-title":"Why have so few proteomic biomarkers \u2018survived\u2019 validation? (Sample size and independent validation considerations","volume":"14","author":"Hern\u00e1ndez","year":"2014","journal-title":"Proteomics"},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib88","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-026-44561-x","article-title":"Isobaric quantitative proteomics reveals altered extracellular matrix, cytoskeletal, and degradation pathways in glaucomatous trabecular meshwork cells","volume":"16","author":"Holden","year":"2026","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib89","doi-asserted-by":"crossref","first-page":"101221","DOI":"10.1016\/j.mam.2023.101221","article-title":"The role of the microbiota in glaucoma","volume":"94","author":"Huang","year":"2023","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108077","article-title":"The aqueous humor proteome of primary open angle glaucoma: an extensive review","volume":"197","author":"Hubens","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib91","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108460","article-title":"Increased ratios of complement factors C3a to C3 in aqueous humor and serum mark glaucoma progression","volume":"204","author":"Hubens","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib92","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1038\/ng.3087","article-title":"Genome-wide analysis of multiethnic cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma","volume":"46","author":"Hysi","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib93","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1038\/s41467-018-05184-7","article-title":"Gut microbiota associations with common diseases and prescription medications in a population-based cohort","volume":"9","author":"Jackson","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib94","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1126\/science.aam9710","article-title":"Deriving genomic diagnoses without revealing patient genomes","volume":"357","author":"Jagadeesh","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2026.101490_bib95","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a020636","article-title":"Differential gene expression in glaucoma","volume":"4","author":"Jakobs","year":"2014","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib96","doi-asserted-by":"crossref","first-page":"7971","DOI":"10.1167\/iovs.15-18088","article-title":"MicroRNA expression in the glaucomatous retina","volume":"56","author":"Jayaram","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib97","doi-asserted-by":"crossref","DOI":"10.1080\/15592294.2025.2566496","article-title":"Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging","volume":"20","author":"Jiang","year":"2025","journal-title":"Epigenetics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib98","first-page":"2307","article-title":"Comparison of different mass spectrometry workflows for the proteomic analysis of tear fluid","volume":"23","author":"Jones","year":"2022","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib99","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/978-1-4939-3106-4_19","article-title":"Statistical aspects in proteomic biomarker discovery","volume":"1362","author":"Jung","year":"2016","journal-title":"Methods Mol. Biol."},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib100","article-title":"Comparison of pattern electroretinograms of glaucoma patients with parafoveal scotoma versus peripheral nasal step","volume":"9","author":"Jung","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib101","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165314","article-title":"Changes to the aqueous humor proteome during glaucoma","volume":"11","author":"Kaeslin","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2026.101490_bib102","doi-asserted-by":"crossref","DOI":"10.1099\/jmm.0.002013","article-title":"Alterations of ocular surface microbiome in glaucoma and its association with dry eye","volume":"74","author":"Kamdougha","year":"2025","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib103","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1167\/iovs.63.9.15","article-title":"Prediagnostic plasma metabolomics and the risk of exfoliation glaucoma","volume":"63","author":"Kang","year":"2022","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib104","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1097\/ICU.0000000000001163","article-title":"Considerations and surgical approach to vitreous, retinal, and chorioretinal biopsy","volume":"36","author":"Kasetty","year":"2025","journal-title":"Curr. Opin. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib105","first-page":"8647","article-title":"An extensive Study of phenol red thread as a novel non-invasive tear sampling technique for proteomics studies: Comparison with two commonly used methods","volume":"23","author":"Kecskem\u00e9ti","year":"2022","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib106","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.survophthal.2022.01.010","article-title":"Metabolomics and lipidomics approaches in human tears: a systematic review","volume":"67","author":"Khanna","year":"2022","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib107","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/s41588-018-0126-8","article-title":"Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma","volume":"50","author":"Khawaja","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib108","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1038\/eye.2012.206","article-title":"The effects of Helicobacter pylori infection on intraocular pressure in anterior uveitis","volume":"26","author":"Kim","year":"2012","journal-title":"Eye"},{"key":"10.1016\/j.preteyeres.2026.101490_bib109","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1167\/iovs.10-6096","article-title":"Investigation of the Association between Helicobacter pylori infection and normal tension glaucoma","volume":"52","author":"Kim","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib110","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1002\/dvdy.330","article-title":"RERE deficiency causes retinal and optic nerve atrophy through degeneration of retinal cells","volume":"250","author":"Kim","year":"2021","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.preteyeres.2026.101490_bib111","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108908","article-title":"Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization","volume":"215","author":"Klaska","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib112","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-9164-8_1","article-title":"Pre- and post-analytical factors in biomarker discovery","volume":"1959","author":"Klont","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib113","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.1038\/s41598-023-30892-6","article-title":"Integrated multi-omics analysis of Alzheimer's disease shows molecular signatures associated with disease progression and potential therapeutic targets","volume":"13","author":"Kodam","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib114","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.3390\/jcm10061180","article-title":"Aqueous humor proteomic alterations associated with visual field index parameters in glaucoma patients: a pilot Study","volume":"10","author":"Kodeboyina","year":"2021","journal-title":"JCM"},{"key":"10.1016\/j.preteyeres.2026.101490_bib115","doi-asserted-by":"crossref","DOI":"10.3389\/fdata.2024.1266031","article-title":"Efficacy of federated learning on genomic data: a study on the UK Biobank and the 1000 Genomes Project","volume":"7","author":"Kolobkov","year":"2024","journal-title":"Front. Big Data"},{"key":"10.1016\/j.preteyeres.2026.101490_bib116","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3390\/metabo10020049","article-title":"A data mining metabolomics exploration of glaucoma","volume":"10","author":"Kouassi Nzoughet","year":"2020","journal-title":"Metabolites"},{"key":"10.1016\/j.preteyeres.2026.101490_bib117","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0161-6420(00)00598-4","article-title":"Relationship between Helicobacter pylori infection and glaucoma","volume":"108","author":"Kountouras","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib118","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/IJG.0b013e31815a34ac","article-title":"No Association between Helicobacter pylori infection or CagA-bearing strains and glaucoma","volume":"17","author":"Kurtz","year":"2008","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.preteyeres.2026.101490_bib119","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ajo.2019.05.015","article-title":"Genetic correlations between diabetes and glaucoma: an analysis of continuous and dichotomous phenotypes","volume":"206","author":"Laville","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib120","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1167\/iovs.11-8514","article-title":"The Vitreous glycoprotein Opticin inhibits preretinal neovascularization","volume":"53","author":"Le Goff","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib121","doi-asserted-by":"crossref","first-page":"28027","DOI":"10.1074\/jbc.M111.331157","article-title":"Opticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesiveness","volume":"287","author":"Le Goff","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.preteyeres.2026.101490_bib122","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1167\/iovs.19-27087","article-title":"Association of corneal hysteresis with Lamina Cribrosa curvature in primary open angle glaucoma","volume":"60","author":"Lee","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib123","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/s41598-022-05273-0","article-title":"Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma","volume":"12","author":"Lee","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib124","doi-asserted-by":"crossref","DOI":"10.7759\/cureus.21004","article-title":"A component or multiple components of bleeding gums May ameliorate both glaucoma and alzheimer's disease","author":"Lehrer","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.preteyeres.2026.101490_bib125","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1167\/iovs.18-24938","article-title":"A metabolomics profiling of glaucoma points to mitochondrial dysfunction, senescence, and polyamines deficiency","volume":"59","author":"Leruez","year":"2018","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib126","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.105576","article-title":"Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma","volume":"14","author":"Li","year":"2025","journal-title":"eLife"},{"key":"10.1016\/j.preteyeres.2026.101490_bib127","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.91407.3","article-title":"Metabolomics identifies and validates serum androstenedione as novel biomarker for diagnosing primary angle closure glaucoma and predicting the visual field progression","volume":"12","author":"Li","year":"2024","journal-title":"eLife"},{"key":"10.1016\/j.preteyeres.2026.101490_bib128","article-title":"A multi-omics atlas of the human retina at single-cell resolution","volume":"3","author":"Liang","year":"2023","journal-title":"Cell Genom."},{"key":"10.1016\/j.preteyeres.2026.101490_bib129","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1007\/s11064-011-0518-y","article-title":"The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension: the expression of myelin proteins in the retina in glaucoma","volume":"36","author":"Liao","year":"2011","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib131","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1007\/s00417-021-05218-9","article-title":"Differences in the eyelid and buccal microbiome of glaucoma patients receiving long-term administration of prostaglandin analog drops","volume":"259","author":"Lim","year":"2021","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib132","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcpro.2023.100654","article-title":"Early proteomic characteristics and changes in the optic nerve head, optic nerve, and retina in a rat model of ocular hypertension","volume":"22","author":"Lin","year":"2023","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib133","doi-asserted-by":"crossref","first-page":"176","DOI":"10.18240\/ijo.2020.01.24","article-title":"Proteome alterations in aqueous humour of primary open angle glaucoma patients","volume":"13","author":"Liu","year":"2020","journal-title":"Int. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib134","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcpro.2021.100117","article-title":"Proteome characterization of glaucoma aqueous humor","volume":"20","author":"Liu","year":"2021","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib135","doi-asserted-by":"crossref","first-page":"6248","DOI":"10.1167\/iovs.13-12779","article-title":"Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry","volume":"54","author":"Liu","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib136","doi-asserted-by":"crossref","first-page":"6382","DOI":"10.1167\/iovs.13-12128","article-title":"Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma","volume":"54","author":"Liu","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib137","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/s41586-020-2975-4","article-title":"Reprogramming to recover youthful epigenetic information and restore vision","volume":"588","author":"Lu","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2026.101490_bib138","first-page":"2841","article-title":"Epigenetic reprogramming to rejuvenate retinal ganglion cells and sustainably reverse glaucoma-induced vision loss","volume":"64","author":"Lu","year":"2023","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib139","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-025-64949-z","article-title":"GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology","volume":"16","author":"Luben","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3892\/ijmm.2021.4916","article-title":"Critical role of mass spectrometry proteomics in tear biomarker discovery for multifactorial ocular diseases","volume":"47","author":"Ma","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib141","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221810095","article-title":"Sodium 4-Phenylbutyrate reduces ocular hypertension by degrading extracellular matrix deposition via activation of MMP9","volume":"22","author":"Maddineni","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib142","doi-asserted-by":"crossref","first-page":"5827","DOI":"10.1038\/s41467-022-33427-1","article-title":"High-resolution genome topology of human retina uncovers super enhancer-promoter interactions at tissue-specific and multifactorial disease loci","volume":"13","author":"Marchal","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib143","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-9744-2_1","article-title":"Introduction to mass spectrometry-based proteomics","volume":"2051","author":"Matthiesen","year":"2020","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib144","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4161\/epi.7.2.18764","article-title":"Basic concepts of epigenetics","volume":"7","author":"Mazzio","year":"2012","journal-title":"Epigenetics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib145","doi-asserted-by":"crossref","DOI":"10.1097\/IJG.0000000000000453","article-title":"Increased global DNA methylation and decreased TGF\u03b21 promoter methylation in glaucomatous Lamina Cribrosa cells","volume":"25","author":"McDonnell","year":"2016","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.preteyeres.2026.101490_bib146","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.ophtha.2024.12.034","article-title":"Accelerated epigenetic aging is associated with faster glaucoma progression","volume":"132","author":"Medeiros","year":"2025","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib147","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s12325-016-0285-x","article-title":"Differential protein expression profiles in glaucomatous trabecular meshwork: an evaluation Study on a small primary open angle glaucoma population","volume":"33","author":"Micera","year":"2016","journal-title":"Adv. Ther."},{"key":"10.1016\/j.preteyeres.2026.101490_bib148","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1136\/bjophthalmol-2020-318166","article-title":"OCT-angiography detects longitudinal microvascular changes in glaucoma: a systematic review","volume":"106","author":"Miguel","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib149","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.kint.2019.02.012","article-title":"Inhibition of urinary stone disease by a multi-species bacterial network ensures healthy oxalate homeostasis","volume":"96","author":"Miller","year":"2019","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib150","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-12858-7","article-title":"Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes","volume":"7","author":"Mirzaei","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib151","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2306153120","article-title":"Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye","volume":"120","author":"Monavarfeshani","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.preteyeres.2026.101490_bib152","doi-asserted-by":"crossref","first-page":"859","DOI":"10.4049\/jimmunol.2200660","article-title":"Multiomics empowers predictive pancreatic cancer immunotherapy","volume":"210","author":"Montagne","year":"2023","journal-title":"J. Immunol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib153","first-page":"1","article-title":"A systematic review of homomorphic encryption and its contributions in healthcare industry","author":"Munjal","year":"2022","journal-title":"Complex Intell. Syst."},{"key":"10.1016\/j.preteyeres.2026.101490_bib154","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1039\/C9MO00192A","article-title":"Aqueous humor metabolite profile of pseudoexfoliation glaucoma is distinctive","volume":"16","author":"Myer","year":"2020","journal-title":"Mol. Omics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib155","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-22536-8","article-title":"Characterization of the microbial profile in tears of patients with primary open-angle glaucoma: results from a pilot study","volume":"15","author":"Navarro-Tapia","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib156","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41576-023-00662-1","article-title":"Non-coding RNAs in disease: from mechanisms to therapeutics","volume":"25","author":"Nemeth","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib157","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00018-008-8303-z","article-title":"Dynamic protein methylation in chromatin biology","volume":"66","author":"Ng","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib158","first-page":"8136","article-title":"Clinical tear fluid Proteomics\u2014A novel tool in glaucoma research","volume":"23","author":"N\u00e4ttinen","year":"2022","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib159","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1136\/bjophthalmol-2020-317454","article-title":"Machine learning to determine relative contribution of modifiable and non-modifiable risk factors of major eye diseases","volume":"106","author":"Nusinovici","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib160","doi-asserted-by":"crossref","DOI":"10.1093\/eep\/dvw006","article-title":"Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study","volume":"2","author":"Nwanaji-Enwerem","year":"2016","journal-title":"Environ. Epigenet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib161","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1001\/jamaophthalmol.2018.5313","article-title":"Association of long-term ambient Black carbon exposure and oxidative stress allelic variants with intraocular pressure in older men","volume":"137","author":"Nwanaji-Enwerem","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.preteyeres.2026.101490_bib162","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1021\/acs.jproteome.8b00016","article-title":"Proteome-Wide evaluation of two common protein quantification methods","volume":"17","author":"O'Connell","year":"2018","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib163","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1167\/iovs.16-20853","article-title":"Conjunctival bacteria flora of glaucoma patients during long-term administration of prostaglandin analog drops","volume":"58","author":"Ohtani","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib164","doi-asserted-by":"crossref","DOI":"10.1172\/JCI153589","article-title":"METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma","volume":"132","author":"Pan","year":"2022","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.preteyeres.2026.101490_bib165","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.ajo.2012.07.023","article-title":"CDKN2B-AS1 genotype\u2013glaucoma feature correlations in primary open-angle glaucoma patients from the United States","volume":"155","author":"Pasquale","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib166","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nrm3314","article-title":"Metabolomics: the apogee of the omic triology","volume":"13","author":"Patti","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib167","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.exer.2013.03.009","article-title":"FOXC1 in human trabecular meshwork cells is involved in regulatory pathway that includes miR-204, MEIS2, and ITG\u03b21","volume":"111","author":"Paylakhi","year":"2013","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib168","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1167\/iovs.11-8872","article-title":"Silencing of Fem1cR3 gene expression in the DBA\/2J Mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity","volume":"53","author":"Pelzel","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib169","article-title":"Proteomic profile analysis of plasma and aqueous humor from glaucoma and non-glaucomatous patients","author":"Pessuti","year":"2024","journal-title":"Preprint. bioRxiv"},{"key":"10.1016\/j.preteyeres.2026.101490_bib170","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2020.110235","article-title":"Vitreous humor endogenous compounds analysis for post-mortem forensic investigation","volume":"310","author":"Pigaiani","year":"2020","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.preteyeres.2026.101490_bib171","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/IJG.0000000000000465","article-title":"A pilot Study to evaluate the oral microbiome and dental health in primary open-angle glaucoma","volume":"26","author":"Polla","year":"2017","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.preteyeres.2026.101490_bib172","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1002\/mas.21691","article-title":"Mass spectrometry\u2010based tear proteomics for noninvasive biomarker discovery","volume":"41","author":"Ponzini","year":"2022","journal-title":"Mass Spectrom. Rev."},{"key":"10.1016\/j.preteyeres.2026.101490_bib173","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1167\/tvst.12.2.32","article-title":"Validation of 16S rRNA gene sequencing of the periocular microbiome and lack of alteration by topical eyedrops","volume":"12","author":"Priluck","year":"2023","journal-title":"Transl. Vis. Sci. Technol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib174","doi-asserted-by":"crossref","first-page":"9766","DOI":"10.1038\/s41598-021-89137-z","article-title":"Elevated dimethylarginine, ATP, cytokines, metabolic remodeling involving tryptophan metabolism and potential microglial inflammation characterize primary open angle glaucoma","volume":"11","author":"Pulukool","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.preteyeres.2026.101490_bib175","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.ophtha.2019.12.025","article-title":"An intraocular pressure polygenic risk Score stratifies multiple primary open-angle glaucoma parameters including treatment intensity","volume":"127","author":"Qassim","year":"2020","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib176","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108047","article-title":"DNA methylation of miR-200 clusters promotes epithelial to mesenchymal transition in human conjunctival epithelial cells","volume":"197","author":"Raji\u0107","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib177","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1093\/hmg\/ddr120","article-title":"Common genetic variants associated with open-angle glaucoma","volume":"20","author":"Ramdas","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib178","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1136\/bjo.2003.031989","article-title":"Immunolocalisation of opticin in the human eye","volume":"88","author":"Ramesh","year":"2004","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib179","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/s41588-019-0351-9","article-title":"Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration","volume":"51","author":"Ratnapriya","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib180","article-title":"GA4GH: international policies and standards for data sharing across genomic research and healthcare","volume":"1","author":"Rehm","year":"2021","journal-title":"Cell Genom."},{"key":"10.1016\/j.preteyeres.2026.101490_bib181","first-page":"6995","article-title":"Proteomics analyses of small extracellular vesicles of aqueous humor: identification and validation of GAS6 and SPP1 as glaucoma markers","volume":"25","author":"Rejas-Gonz\u00e1lez","year":"2024","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib182","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/nbt1235","article-title":"Protein biomarker discovery and validation: the long and uncertain path to clinical utility","volume":"24","author":"Rifai","year":"2006","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib183","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1038\/s41467-019-10933-3","article-title":"Estimating the success of re-identifications in incomplete datasets using generative models","volume":"10","author":"Rocher","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib184","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0318125","article-title":"Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-\u03b21 provides insights into the pathogenesis of pseudoexfoliation glaucoma","volume":"20","author":"Roodnat","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.preteyeres.2026.101490_bib185","first-page":"4029","article-title":"Multi-Omics approach for studying tears in treatment-na\u00efve glaucoma patients","volume":"20","author":"Rossi","year":"2019","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib186","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.arr.2016.05.012","article-title":"From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma","volume":"29","author":"Sacc\u00e0","year":"2016","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.preteyeres.2026.101490_bib187","article-title":"Functional Activity of Matrix Metalloproteinases 2 and 9 in tears of Patients with Glaucoma","volume":"58","author":"Sahay","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib188","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.14336\/AD.2024.0103","article-title":"Glial cell activation and immune responses in glaucoma: a systematic review of human postmortem studies of the retina and optic nerve","volume":"15","author":"Salkar","year":"2024","journal-title":"Aging Dis"},{"key":"10.1016\/j.preteyeres.2026.101490_bib189","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5539\/gjhs.v6n7p13","article-title":"Association between Helicobacter Pylori infection and primary open angle glaucoma","volume":"6","author":"Samarai","year":"2014","journal-title":"Global J. Health Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib190","doi-asserted-by":"crossref","first-page":"8018","DOI":"10.1007\/s12035-019-01658-x","article-title":"Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo","volume":"56","author":"Schl\u00fcter","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib191","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1093\/hmg\/ddaa021","article-title":"Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1","volume":"29","author":"Schmitt","year":"2020","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib192","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1750-1326-9-39","article-title":"Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury","volume":"9","author":"Schmitt","year":"2014","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.preteyeres.2026.101490_bib193","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1016\/j.survophthal.2008.08.002","article-title":"Adherence and persistence with glaucoma therapy","volume":"53","author":"Schwartz","year":"2008","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib194","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1002\/pmic.201300075","article-title":"The human eye proteome Project: perspectives on an emerging proteome","volume":"13","author":"Semba","year":"2013","journal-title":"Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib195","doi-asserted-by":"crossref","DOI":"10.1126\/science.add1236","article-title":"ApoE isoform\u2013 and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy","volume":"379","author":"Seo","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2026.101490_bib196","doi-asserted-by":"crossref","DOI":"10.1080\/08916934.2025.2480594","article-title":"Unveiling causal pathways in autoimmune diseases: a multi-omics approach","volume":"58","author":"Sha","year":"2025","journal-title":"Autoimmunity"},{"key":"10.1016\/j.preteyeres.2026.101490_bib197","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1167\/iovs.17-23434","article-title":"Proteomic alterations in aqueous humor from patients with primary open angle glaucoma","volume":"59","author":"Sharma","year":"2018","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib198","series-title":"Glaucoma - Basic and Clinical Aspects","article-title":"Emerging concept of genetic and epigenetic contribution to the manifestation of glaucoma","author":"Shastry","year":"2013"},{"key":"10.1016\/j.preteyeres.2026.101490_bib199","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1093\/hmg\/ddy053","article-title":"Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma","volume":"27","author":"Shiga","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib200","doi-asserted-by":"crossref","DOI":"10.3389\/fopht.2023.1217125","article-title":"Optical coherence tomography and optical coherence tomography angiography: essential tools for detecting glaucoma and disease progression","volume":"3","author":"Shiga","year":"2023","journal-title":"Front. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib201","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12886-022-02395-x","article-title":"The microbiomes of the eyelid and buccal area of patients with uveitic glaucoma","volume":"22","author":"Shin","year":"2022","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib202","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jphs.2020.12.009","article-title":"Potential roles of astrocytes and M\u00fcller cells in the pathogenesis of glaucoma","volume":"145","author":"Shinozaki","year":"2021","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib203","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1001\/jamaophthalmol.2021.2440","article-title":"Association of monogenic and polygenic risk with the prevalence of open-angle glaucoma","volume":"139","author":"Siggs","year":"2021","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.preteyeres.2026.101490_bib204","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ophtha.2022.01.005","article-title":"Genome-Wide Association Study identifies two common loci associated with pigment dispersion Syndrome\/Pigmentary glaucoma and implicates myopia in its development","volume":"129","author":"Simcoe","year":"2022","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib205","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cell.2019.02.048","article-title":"The missing diversity in human genetic studies","volume":"177","author":"Sirugo","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2026.101490_bib206","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.ophtha.2022.11.009","article-title":"Corneal hysteresis for the diagnosis of glaucoma and assessment of progression risk: a report by the American Academy of ophthalmology","volume":"130","author":"Sit","year":"2023","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib207","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1080\/13816810.2018.1432061","article-title":"The relationship between HDAC6, CXCR3, and SIRT1 genes expression levels with progression of primary open-angle glaucoma","volume":"39","author":"Siwak","year":"2018","journal-title":"Ophthalmic Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib208","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10792-020-01587-y","article-title":"Glaucoma patients have an increased level of trimethylamine, a toxic product of gut bacteria, in the aqueous humor: a pilot study","volume":"41","author":"Skrzypecki","year":"2021","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib209","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jchromb.2007.10.042","article-title":"Statistical data processing in clinical proteomics","volume":"866","author":"Smit","year":"2008","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib210","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201900029","article-title":"Targeted and untargeted proteomics approaches in biomarker development","volume":"20","author":"Sobsey","year":"2020","journal-title":"Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib211","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/gepi.21886","article-title":"Meta-analysis of genome-wide Association studies identifies novel loci associated with optic disc morphology","volume":"39","author":"Springelkamp","year":"2015","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib212","first-page":"438","article-title":"New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics","volume":"26","author":"Springelkamp","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib213","doi-asserted-by":"crossref","first-page":"6257","DOI":"10.3390\/ijms25116257","article-title":"Exploring the ocular surface microbiome and tear proteome in glaucoma","volume":"25","author":"Sp\u00f6rri","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib214","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2023.101203","article-title":"Towards modifying the genetic predisposition for glaucoma: an overview of the contribution and interaction of genetic and environmental factors","volume":"93","author":"Stuart","year":"2023","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib215","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1167\/iovs.66.1.43","article-title":"Tubulin acetylation enhances microtubule stability in trabecular meshwork cells under mechanical stress","volume":"66","author":"Su","year":"2025","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib216","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/s41586-023-06592-6","article-title":"Plasma proteomic associations with genetics and health in the UK Biobank","volume":"622","author":"Sun","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.preteyeres.2026.101490_bib217","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11095-019-2569-8","article-title":"Review of biomarkers in ocular matrices: challenges and opportunities","volume":"36","author":"Tamhane","year":"2019","journal-title":"Pharm. Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib218","doi-asserted-by":"crossref","DOI":"10.1038\/s41592-023-02110-8","article-title":"Spatially resolved multiomics","volume":"20","author":"Tang","year":"2023","journal-title":"Nat. Methods"},{"key":"10.1016\/j.preteyeres.2026.101490_bib219","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.621146","article-title":"Metabolomic profiling of aqueous humor and plasma in primary open angle glaucoma patients points towards novel diagnostic and therapeutic strategy","volume":"12","author":"Tang","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib220","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2022.136978","article-title":"Isozyme-specific histone deacetylase 1\/2 inhibitor K560 attenuates oxidative stress-induced retinal cell death","volume":"793","author":"Tawarayama","year":"2023","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.preteyeres.2026.101490_bib221","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/s41431-020-00771-z","article-title":"Reflections on dynamic consent in biomedical research: the story so far","volume":"29","author":"Teare","year":"2021","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib222","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.preteyeres.2026.101490_bib223","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.aaz1776","article-title":"The GTEx Consortium atlas of genetic regulatory effects across human tissues","volume":"369","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2026.101490_bib224","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1126\/science.1251546","article-title":"Enabling the genomic revolution in Africa","volume":"344","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.preteyeres.2026.101490_bib225","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/ng.661","article-title":"Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma","volume":"42","author":"Thorleifsson","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib226","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/s41392-025-02438-x","article-title":"Single-cell RNA-seq reveals cell type-specific molecular and genetic associations with primary open-angle glaucoma","volume":"10","author":"Tian","year":"2025","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.preteyeres.2026.101490_bib227","first-page":"1","article-title":"Investigation of the Association between the oral and the gut microbiome in glaucoma","volume":"11","author":"Toft-Kehler","year":"2020","journal-title":"J. Clin. Exp. Ophthalmol."},{"issue":"1","key":"10.1016\/j.preteyeres.2026.101490_bib228","article-title":"Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment","volume":"11","author":"Tolman","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.preteyeres.2026.101490_bib229","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.3390\/ijms25052822","article-title":"Exploring epigenetic modifications as potential biomarkers and therapeutic targets in glaucoma","volume":"25","author":"Tonti","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib230","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.101988","article-title":"Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction","volume":"43","author":"Tribble","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib231","doi-asserted-by":"crossref","first-page":"10339","DOI":"10.1073\/pnas.2001250117","article-title":"Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis","volume":"117","author":"van Zyl","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.preteyeres.2026.101490_bib232","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2200914119","article-title":"Cell atlas of the human ocular anterior segment: Tissue-specific and shared cell types","volume":"119","author":"van Zyl","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.preteyeres.2026.101490_bib233","first-page":"1400","article-title":"Complement System proteins in the human aqueous humor and their Association with primary open-angle glaucoma","volume":"13","author":"Vashishtha","year":"2023","journal-title":"J. Phys. Math."},{"key":"10.1016\/j.preteyeres.2026.101490_bib234","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1167\/iovs.65.2.7","article-title":"Glaucoma patients have a lower abundance of butyrate-producing taxa in the gut","volume":"65","author":"Vergroesen","year":"2024","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib235","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00203-018-1505-3","article-title":"Insights into the human oral microbiome","volume":"200","author":"Verma","year":"2018","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib236","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.cell.2023.12.006","article-title":"A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma","volume":"187","author":"Verma","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2026.101490_bib237","doi-asserted-by":"crossref","first-page":"3391","DOI":"10.1167\/iovs.10-6165","article-title":"Coordinated regulation of extracellular matrix synthesis by the MicroRNA-29 family in the trabecular meshwork","volume":"52","author":"Villarreal","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib238","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1016\/j.ymthe.2020.12.030","article-title":"TET-dependent GDF7 hypomethylation impairs aqueous humor outflow and serves as a potential therapeutic target in glaucoma","volume":"29","author":"Wan","year":"2021","journal-title":"Mol. Ther."},{"key":"10.1016\/j.preteyeres.2026.101490_bib239","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1167\/iovs.19-27939","article-title":"Dysbiosis modulates ocular surface inflammatory response to liposaccharide","volume":"60","author":"Wang","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib240","article-title":"Identification of immune-related biomarkers for glaucoma using gene expression profiling","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib241","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1007\/s10620-012-2259-4","article-title":"Butyrate enhances intestinal epithelial barrier function via Up-Regulation of tight junction protein Claudin-1 transcription","volume":"57","author":"Wang","year":"2012","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib242","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/ng.3931","article-title":"Classification of common human diseases derived from shared genetic and environmental determinants","volume":"49","author":"Wang","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib243","doi-asserted-by":"crossref","first-page":"6895","DOI":"10.2147\/JIR.S480809","article-title":"Increased intestinal inflammation and permeability in glaucoma","volume":"17","author":"Wang","year":"2024","journal-title":"JIR"},{"key":"10.1016\/j.preteyeres.2026.101490_bib244","author":"Weinreb"},{"key":"10.1016\/j.preteyeres.2026.101490_bib245","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.1093\/hmg\/ddr382","article-title":"Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA","volume":"20","author":"Wiggs","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib246","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002654","article-title":"Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma","volume":"8","author":"Wiggs","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib247","doi-asserted-by":"crossref","unstructured":"Wiggs, J. Pasquale LR. Glaucoma Genetics: Lessons Learned and the New Frontier. Ophthalmol Glaucoma, 8(5S), 2025, S27-S32.","DOI":"10.1016\/j.ogla.2025.07.009"},{"key":"10.1016\/j.preteyeres.2026.101490_bib248","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3389\/fimmu.2020.00512","article-title":"Versican\u2014A critical extracellular matrix regulator of immunity and inflammation","volume":"11","author":"Wight","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib249","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.annepidem.2011.03.006","article-title":"A prospective Study of Diabetes, lifestyle factors, and glaucoma among African-American women","volume":"21","author":"Wise","year":"2011","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib250","doi-asserted-by":"crossref","first-page":"4868","DOI":"10.1016\/j.cell.2023.09.012","article-title":"Liquid-biopsy proteomics combined with AI identifies cellular drivers of eye aging and disease in vivo","volume":"186","author":"Wolf","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.preteyeres.2026.101490_bib251","doi-asserted-by":"crossref","DOI":"10.1136\/bmjophth-2023-001547","article-title":"Effect of the gut microbiome in glaucoma risk from the causal perspective","volume":"9","author":"Wu","year":"2024","journal-title":"BMJ Open Ophth"},{"key":"10.1016\/j.preteyeres.2026.101490_bib252","article-title":"High-Throughput tear proteomics via In-Capillary digestion for biomarker discovery","volume":"25","author":"Xiao","year":"2024","journal-title":"Indian J. Manag. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib253","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108785","article-title":"DZNep protects against retinal ganglion cell death in an NMDA-induced mouse model of retinal degeneration","volume":"212","author":"Xiao","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib254","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3390\/biom14030307","article-title":"Untargeted and oxylipin-targeted metabolomics Study on the plasma samples of primary open-angle glaucoma patients","volume":"14","author":"Xu","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.preteyeres.2026.101490_bib255","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13737","article-title":"Stress induced aging in mouse eye","volume":"21","author":"Xu","year":"2022","journal-title":"Aging Cell"},{"key":"10.1016\/j.preteyeres.2026.101490_bib256","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.701322","article-title":"Demyelination of the optic nerve: an underlying factor in Glaucoma?","volume":"13","author":"Xue","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib257","first-page":"48","article-title":"Fibrosis-Related gene and protein expression in normal and glaucomatous trabecular meshwork cells","volume":"66","author":"Yang","year":"2025","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib258","doi-asserted-by":"crossref","DOI":"10.1080\/20002297.2021.1962125","article-title":"Analysis of oral microbiome in glaucoma patients using machine learning prediction models","volume":"13","author":"Yoon","year":"2021","journal-title":"J. Oral Microbiol."},{"key":"10.1016\/j.preteyeres.2026.101490_bib259","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3390\/cells11081301","article-title":"Emerging evidence of noncoding RNAs in bleb scarring after glaucoma filtration surgery","volume":"11","author":"Yu","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.preteyeres.2026.101490_bib260","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1186\/s12967-024-05152-4","article-title":"Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks","volume":"22","author":"Yun","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.preteyeres.2026.101490_bib261","doi-asserted-by":"crossref","first-page":"24057","DOI":"10.18632\/aging.202251","article-title":"Age-related DNA methylation changes are sex-specific: a comprehensive assessment","volume":"12","author":"Yusipov","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.preteyeres.2026.101490_bib262","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000330053","article-title":"Histological presence of Helicobacter pylori bacteria in the trabeculum and Iris of patients with primary open-angle glaucoma","volume":"47","author":"Zavos","year":"2011","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib263","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.1038\/s41467-023-38466-w","article-title":"Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank","volume":"14","author":"Zeleznik","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.preteyeres.2026.101490_bib264","doi-asserted-by":"crossref","first-page":"5238","DOI":"10.1167\/iovs.15-17059","article-title":"The relationship between Helicobacter pylori infection and open-angle glaucoma: a meta-analysis","volume":"56","author":"Zeng","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib265","doi-asserted-by":"crossref","first-page":"4674","DOI":"10.1021\/acs.jproteome.4c00593","article-title":"Targeted proteomics profiling for biomarker discovery in glaucoma using the olink proteomics platform","volume":"23","author":"Zhang","year":"2024","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib266","article-title":"Binocular indirect ophthalmo microscope-assistant gas-perfused pars plana vitrectomy: a novel technique for vitreous sample acquisition","volume":"95","author":"Zhang","year":"2016","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.preteyeres.2026.101490_bib267","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1002\/pmic.201600229","article-title":"The proteome of normal human retrobulbar optic nerve and sclera","volume":"16","author":"Zhang","year":"2016","journal-title":"Proteomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib268","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2025.110386","article-title":"A multi-omics study reveals molecular characteristics and therapeutic targets of salidroside in reducing TGF-\u03b22-induced ECM expression","volume":"256","author":"Zhang","year":"2025","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib269","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2024.1324893","article-title":"Absence of causative genetic association between Helicobacter pylori infection and glaucoma: a bidirectional two-sample mendelian randomization study","volume":"15","author":"Zhang","year":"2024","journal-title":"Front. Genet."},{"key":"10.1016\/j.preteyeres.2026.101490_bib270","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.neuroscience.2012.07.056","article-title":"Valproate promotes survival of retinal ganglion cells in a rat model of optic nerve crush","volume":"224","author":"Zhang","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.preteyeres.2026.101490_bib271","doi-asserted-by":"crossref","unstructured":"Zhao, H. & Winchester, L. High throughput proteomics using the SomaLogic platform. Cerebrospinal Fluid (CSF) Proteomics 2914, 165\u2013181.","DOI":"10.1007\/978-1-0716-4462-1_13"},{"key":"10.1016\/j.preteyeres.2026.101490_bib272","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ogla.2021.12.006","article-title":"Mitochondrial dysfunction in primary open-angle glaucoma characterized by Flavoprotein fluorescence at the optic nerve head","volume":"5","author":"Zhou","year":"2022","journal-title":"Ophthalmol Glaucoma"},{"key":"10.1016\/j.preteyeres.2026.101490_bib273","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1016\/j.jprot.2012.04.053","article-title":"In-depth analysis of the human tear proteome","volume":"75","author":"Zhou","year":"2012","journal-title":"J. Proteonomics"},{"key":"10.1016\/j.preteyeres.2026.101490_bib274","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2019.111802","article-title":"Role of the long noncoding RNA H19 in TGF-\u03b21-induced Tenon's capsule fibroblast proliferation and extracellular matrix deposition","volume":"387","author":"Zhu","year":"2020","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.preteyeres.2026.101490_bib275","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.3390\/cells12172131","article-title":"Astrocytes in the optic nerve are heterogeneous in their reactivity to glaucomatous injury","volume":"12","author":"Zhu","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.preteyeres.2026.101490_bib276","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1167\/iovs.11-8837","article-title":"Topical ocular sodium 4-Phenylbutyrate rescues glaucoma in a Myocilin Mouse model of primary open-angle glaucoma","volume":"53","author":"Zode","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.preteyeres.2026.101490_bib277","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s13072-019-0311-8","article-title":"The role of cigarette smoke-induced epigenetic alterations in inflammation","volume":"12","author":"Zong","year":"2019","journal-title":"Epigenetics Chromatin"}],"container-title":["Progress in Retinal and Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S135094622600056X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S135094622600056X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:31:48Z","timestamp":1788575508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S135094622600056X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":276,"alternative-id":["S135094622600056X"],"URL":"https:\/\/doi.org\/10.1016\/j.preteyeres.2026.101490","relation":{},"ISSN":["1350-9462"],"issn-type":[{"value":"1350-9462","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcending genome-wide association studies to create useful multi-omic views of glaucoma","name":"articletitle","label":"Article Title"},{"value":"Progress in Retinal and Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.preteyeres.2026.101490","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101490"}}