{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:16:44Z","timestamp":1790403404322,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T00:00:00Z","timestamp":1484179200000},"content-version":"vor","delay-in-days":377,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Preventive Veterinary Medicine"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.prevetmed.2015.11.004","type":"journal-article","created":{"date-parts":[[2015,11,18]],"date-time":"2015-11-18T18:16:03Z","timestamp":1447870563000},"page":"71-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Analysis of Q fever in Dutch dairy goat herds and assessment of control measures by means of a transmission model"],"prefix":"10.1016","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3779-4460","authenticated-orcid":false,"given":"D.M.","family":"Bontje","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Backer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Hogerwerf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.I.J.","family":"Roest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.J.W.","family":"van Roermund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prevetmed.2015.11.004_bib0005","first-page":"29","article-title":"Verslag Q-fever op 13 melkgeitenbedrijven van maart 29 pagina.s","author":"Animal Health Service","year":"2008"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0010","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1051\/vetres:2005010","article-title":"Is Q Fever an emerging or re-emerging zoonosis?","volume":"36","author":"Arricau-Bouvery","year":"2005","journal-title":"Vet. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0015","doi-asserted-by":"crossref","first-page":"4392","DOI":"10.1016\/j.vaccine.2005.04.010","article-title":"Effect of vaccination with phase I and phase II Coxiella burnetii vaccines in pregnant goats","volume":"23","author":"Arricau-Bouvery","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0020","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1051\/vetres:2003017","article-title":"Experimental Coxiella burnetii infection in pregnant goats: excretion routes","volume":"34","author":"Arricau-Bouvery","year":"2003","journal-title":"Vet. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0025","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1136\/vr.157.23.737","article-title":"Spread of Coxiella burnetii infection in a flock of sheep after an episode of Q fever","volume":"157","author":"Berri","year":"2005","journal-title":"Vet. Rec."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0030","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.rvsc.2006.11.001","article-title":"Goats may experience reproductive failures and shed Coxiella burnetii at two successive parturitions after a Q fever infection","volume":"83","author":"Berri","year":"2007","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0035","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/104063870001200505","article-title":"Coxiella burnetii infection is associated with placentitis in cases of bovine abortion","volume":"12","author":"Bildfell","year":"2000","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0040","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1186\/1471-2334-13-488","article-title":"Human dose response relation for airborne exposure to Coxiella burnetii","volume":"13","author":"Brooke","year":"2013","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0045","series-title":"Manual of Clinical Microbiology","first-page":"1062","article-title":"Coxiella","author":"Brouqui","year":"2007"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0050","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/clinids\/5.4.800","article-title":"Classics in infectious-diseases-experimental studies on the Virus of Q-Fever (Reprinted)","volume":"5","author":"Burnet","year":"1983","journal-title":"Rev. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0055","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1297-9716-42-68","article-title":"Modelling effectiveness of herd level vaccination against Q fever in dairy cattle","volume":"42","author":"Courcoul","year":"2011","journal-title":"Vet. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0060","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1098\/rspb.2010.0575","article-title":"Spread of Q fever within dairy cattle herds: key parameters inferred using a Bayesian approach","volume":"277","author":"Courcoul","year":"2010","journal-title":"Proc. R. Soc. B"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0065","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1001\/jama.1947.02880120008004","article-title":"Q-Fever in the United-States .4. Isolation and identification of Rickettsias in an outbreak among stock handlers and slaughterhouse workers","volume":"133","author":"Cox","year":"1947","journal-title":"Jama-J. Am. Med. Assoc."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0070","doi-asserted-by":"crossref","first-page":"6516","DOI":"10.1128\/AEM.05097-11","article-title":"Detection of Coxiella burnetii in complex matrices by using multiplex quantitative PCR during a major Q fever outbreak in The Netherlands","volume":"77","author":"de Bruin","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0075","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1574-695X.2011.00892.x","article-title":"Assessment of vaccination by a phase I Coxiella burnetii-inactivated vaccine in goat herds in clinical Q fever situation","volume":"64","author":"de Cremoux","year":"2012","journal-title":"Fems Immunol. Med. Microbiol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0080","series-title":"Sherris Medical Microbiology: An Introduction to Infectious Diseases","first-page":"471","article-title":"Rickettsia, Coxiella, Ehrlichia and Bartonella","author":"Drew","year":"2004"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0085","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.2903\/j.efsa.2010.1595","article-title":"Scientific opinion on Q fever","volume":"8","author":"EFSA","year":"2010","journal-title":"EFSA J."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0090","unstructured":"EMA, 2012.Coxevac: EPAR - Product Information. In: Agency, E.M. (Ed.) European Medicine Agency, Coxevac - inactivated Coxiella burnetii vaccine product information."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0095","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3201\/eid0703.017308","article-title":"Goat-associated Q fever: a new disease in Newfoundland","volume":"7","author":"Hatchette","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0100","doi-asserted-by":"crossref","first-page":"5410","DOI":"10.1128\/AEM.00677-12","article-title":"Detection of Coxiella burnetii DNA in inhalable airborne dust samples from goat farms after mandatory culling","volume":"78","author":"Hogerwerf","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0105","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1297-9716-44-28","article-title":"Dairy goat demography and Q fever infection dynamics","volume":"44","author":"Hogerwerf","year":"2013","journal-title":"Vet. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0110","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.tvjl.2014.02.015","article-title":"Test and cull of high risk Coxiella burnetii infected pregnant dairy goats is not feasible due to poor test performance","volume":"200","author":"Hogerwerf","year":"2014","journal-title":"Vet. J."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0115","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3201\/eid1703.101157","article-title":"Reduction of Coxiella burnetii prevalence by vaccination of goats and sheep, the Netherlands","volume":"17","author":"Hogerwerf","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0120","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1177\/104063871102300118","article-title":"Interlaboratory comparison of real-time polymerase chain reaction methods to detect Coxiella burnetii, the causative agent of Q fever","volume":"23","author":"Jones","year":"2011","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0125","series-title":"Modeling Infectious Diseases in Humans and Animals","author":"Keeling","year":"2008"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0130","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3201\/eid1504.081612","article-title":"Multigenotype Q fever outbreak, the Netherlands","volume":"15","author":"Klaassen","year":"2009","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0135","first-page":"254","article-title":"Q-Fever studies .14: observations on the Pathogenesis of the experimental infection induced in sheep by the intravenous route","volume":"55","author":"Lennette","year":"1952","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0140","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/infdis\/173.2.484","article-title":"Route of infection determines the clinical manifestations of acute Q fever","volume":"173","author":"Marrie","year":"1996","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0145","series-title":"The Biology of Coxiella burnetii","first-page":"223","article-title":"The development cycle of Coxiella burnetii, Q fever","author":"McCaul","year":"1991"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0150","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1128\/JB.147.3.1063-1076.1981","article-title":"Developmental cycle of Coxiella burnetii: structure and morphogenesis of vegetative and sporogenic differentiations","volume":"147","author":"McCaul","year":"1981","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0155","first-page":"60","article-title":"Placentitis and abortion in goats and sheep in Ontario caused by Coxiella-Burnetii","volume":"24","author":"Palmer","year":"1983","journal-title":"Can. Vet. J.-Revue Vet. Can."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0160","unstructured":"RIVM, 2012. RijksinstituutvoorVolksgezondheiden Milieu (RIVM), the Dutch National Institute for Public Health and the Environment. http:\/\/rivm.nl\/Onderwerpen\/Q\/Q_koorts (accessed: 11.12.)."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0165","series-title":"Coxiella burnetii in Pregnant Goats. Faculty of Veterinary Medicine","first-page":"200","author":"Roest","year":"2013"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0170","unstructured":"Roest, H.I.J., Dinkla, A., van Rotterdam, B., de Bruin, A., Dercksen, D., Vellema, P., 2011. Overleving van Coxiella burnetii in geitenmest. WUR Report 11\/CVI0212. Wageningen University and Research (WUR)."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0175","doi-asserted-by":"crossref","first-page":"668","DOI":"10.3201\/eid1704.101562","article-title":"Molecular epidemiology of Coxiella burnetii from ruminants in Q fever outbreak, the Netherlands","volume":"17","author":"Roest","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0950268810002268","article-title":"The Q fever epidemic in The Netherlands: history, onset, response and reflection","volume":"139","author":"Roest","year":"2011","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0185","doi-asserted-by":"crossref","first-page":"e48949","DOI":"10.1371\/journal.pone.0048949","article-title":"Q fever in pregnant goats: pathogenesis and excretion of Coxiella burnetii","volume":"7","author":"Roest","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0190","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1128\/AEM.00690-08","article-title":"Coxiella burnetii shedding Routes and antibody Response after outbreaks of Q fever-induced abortion in dairy goat herds","volume":"75","author":"Rousset","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0195","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1469-0691.2008.02220.x","article-title":"Efficiency of a phase 1 vaccine for the reduction of vaginal Coxiella burnetii shedding in a clinically affected goat herd","volume":"15","author":"Rousset","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0200","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jcpa.2006.06.003","article-title":"Experimental Coxiella burnetii infection in pregnant goats: a histopathological and immunohistochemical study","volume":"135","author":"Sanchez","year":"2006","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0205","first-page":"376","article-title":"Coxiella-Burnetti (Q-Fever) abortion storms in goat herds after attendance at an annual fair","volume":"35","author":"Sanford","year":"1994","journal-title":"Can. Vet. J.-Revue Vet. Can."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0210","first-page":"7","article-title":"Seroprevalence and risk factors of Q fever in goats on commercial dairy goat farms in the Netherlands, 2009\u20132010","author":"Schimmer","year":"2011","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0215","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2334-10-69","article-title":"The use of a geographic information system to identify a dairy goat farm as the most likely source of an urban Q-fever outbreak","volume":"10","author":"Schimmer","year":"2010","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0220","unstructured":"Schuiling, H.J., 2007. Prolonged lactations in goats Wageningen UR Livestock Research Animal Sciences Group."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0225","first-page":"521","article-title":"Comparison of the efficacy of Q fever vaccines against Coxiella burnetii experimental challenge in pregnant goats","volume":"990","author":"Souriau","year":"2003","journal-title":"Rickettsiology: Present Future Dir."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0230","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1128\/IAI.73.4.2469-2477.2005","article-title":"Q fever pneumonia: virulence of Coxiella burnetii pathovars in a murine model of aerosol infection","volume":"73","author":"Stein","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0235","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1128\/MMBR.25.3.285-293.1961","article-title":"Airborne Q fever","volume":"25","author":"Tigertt","year":"1961","journal-title":"Bacteriol. Rev."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0240","doi-asserted-by":"crossref","first-page":"887","DOI":"10.3201\/eid1805.111907","article-title":"Epidemic genotype of Coxiella burnetii among goats, sheep, and humans in the Netherlands","volume":"18","author":"Tilburg","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0245","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.prevetmed.2013.06.002","article-title":"Economic assessment of Q fever in the Netherlands","volume":"112","author":"Van Asseldonk","year":"2013","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.prevetmed.2015.06.010","article-title":"Economic aspects of Q fever control in dairy goats","volume":"121","author":"Van Asseldonk","year":"2015","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0255","article-title":"Demography of Q fever seroprevalence in sheep and goats in The Netherlands in 2008","author":"Van den Brom","year":"2012","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0260","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1136\/vr.100304","article-title":"Coxiella burnetii in bulk tank milk samples from dairy goat and dairy sheep farms in The Netherlands in 2008","volume":"170","author":"Van den Brom","year":"2012","journal-title":"Vet. Rec."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0265","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.smallrumres.2009.09.022","article-title":"Q fever outbreaks in small ruminants and people in the Netherlands","volume":"86","author":"Van den Brom","year":"2009","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0270","first-page":"A1845","article-title":"[Three years of Q fever in the Netherlands: faster diagnosis]","volume":"154","author":"Van der Hoek","year":"2010","journal-title":"Ned Tijdschr Geneeskd"},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0275","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0021-9975(08)80254-X","article-title":"Immunocytochemical demonstration of Coxiella burnetii antigen in the fetal placenta of naturally infected sheep and cattle","volume":"109","author":"Van Moll","year":"1993","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0280","unstructured":"VWZ, 2010. Evaluatiecommissie Q-koorts: Rapport van verwerping tot verheffing. In: Ministerie van Volksgezondheid Welzijn en Sport (Ed.) Opmeer dukkerij, Den Haag, Den Haag, 133."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0285","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.2307\/4587909","article-title":"Q fever in California. IV. Occurrence of Coxiella burnetii in the placenta of naturally infected sheep","volume":"66","author":"Welsh","year":"1951","journal-title":"Public Health Rep."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0290","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1749-6632.1958.tb35409.x","article-title":"Air-Borne Transmission of Q fever\u2014the role of parturition in the generation of infective aerosols","volume":"70","author":"Welsh","year":"1958","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.prevetmed.2015.11.004_bib0295","unstructured":"Wolfram Research Inc, 2012. Mathematica. Champaign, Illinois, USA."}],"container-title":["Preventive Veterinary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167587715300441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167587715300441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T14:52:30Z","timestamp":1599835950000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167587715300441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":59,"alternative-id":["S0167587715300441"],"URL":"https:\/\/doi.org\/10.1016\/j.prevetmed.2015.11.004","relation":{},"ISSN":["0167-5877"],"issn-type":[{"value":"0167-5877","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of Q fever in Dutch dairy goat herds and assessment of control measures by means of a transmission model","name":"articletitle","label":"Article Title"},{"value":"Preventive Veterinary Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prevetmed.2015.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V.","name":"copyright","label":"Copyright"}]}}