{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T17:31:11Z","timestamp":1776360671658,"version":"3.51.2"},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Prostate International"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.prnil.2022.06.002","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T21:35:07Z","timestamp":1655760907000},"page":"213-217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Short course of dutasteride in treatment of a refractory category IIIB chronic prostatitis (A placebo-controlled study)"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9679-4241","authenticated-orcid":false,"given":"Ahmed","family":"Higazy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.A.","family":"Shorbagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Shabayek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Radwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George N.","family":"Halim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Osman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarek","family":"Osman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.prnil.2022.06.002_bib1","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.urology.2008.09.074","article-title":"Clinical phenotyping of patients with chronic prostatitis\/chronic pelvic pain syndrome and correlation with symptom severity","volume":"73","author":"Shoskes","year":"2009","journal-title":"Urology [Internet]"},{"key":"10.1016\/j.prnil.2022.06.002_bib2","series-title":"Evidence-Based Urology [Internet]","first-page":"111","article-title":"Treatment of chronic prostatitis\/chronic pelvic pain syndrome","author":"Nickel","year":"2010"},{"issue":"4","key":"10.1016\/j.prnil.2022.06.002_bib3","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.juro.2011.05.071","article-title":"Dutasteride reduces prostatitis symptoms compared with placebo in men enrolled in the REDUCE Study","volume":"186","author":"Nickel","year":"2011","journal-title":"J Urol [Internet]"},{"issue":"3","key":"10.1016\/j.prnil.2022.06.002_bib4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/jama.282.3.236","article-title":"NIH consensus definition and classification of prostatitis","volume":"282","author":"Krieger","year":"1999","journal-title":"JAMA, J Am Med Assoc [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib5","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.prnil.2022.03.002","article-title":"Association between predictors of progression of benign prostatic hyperplasia and moderate-to-severe prostatitis-like symptoms: a propensity score\u2013matched analysis","volume":"10","author":"Lee","year":"2022","journal-title":"Prostate Int [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/pcan.2008.42","article-title":"Clinical phenotyping in chronic prostatitis\/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes","volume":"12","author":"Shoskes","year":"2009","journal-title":"Prostate Cancer Prostatic Dis [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib7","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.prnil.2022.03.004","article-title":"Prostate diseases and microbiome in the prostate, gut, and urine","volume":"10","author":"Miyake","year":"2022","journal-title":"Prostate Int [Internet]"},{"issue":"4","key":"10.1016\/j.prnil.2022.06.002_bib8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S0094-0143(05)70056-2","article-title":"Effective office management of chronic prostatitis","volume":"25","author":"Nickel","year":"1998","journal-title":"Urol Clin [Internet]"},{"issue":"1","key":"10.1016\/j.prnil.2022.06.002_bib9","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/01.ju.0000101487.83730.80","article-title":"A prospective, 1-year trial using saw palmetto versus finasteride in the treatment of category III prostatitis\/chronic pelvic pain syndrome","volume":"171","author":"Kaplan","year":"2004","journal-title":"J Urol [Internet]"},{"key":"10.1016\/j.prnil.2022.06.002_bib10","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1007\/s11255-021-02878-8","article-title":"Rezum: a novel minimally invasive treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia. A review article","author":"Higazy","year":"2021","journal-title":"Int Urol Nephrol [Internet]"},{"issue":"13","key":"10.1016\/j.prnil.2022.06.002_bib11","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1056\/NEJMoa0908127","article-title":"Effect of dutasteride on the risk of prostate cancer","volume":"362","author":"Andriole","year":"2010","journal-title":"N Engl J Med [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib12","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.prnil.2019.11.005","article-title":"Improvement of the symptoms of lower urinary tract and sexual dysfunction with tadalafil and solifenacin after the treatment of benign prostatic hyperplasia with dutasteride","volume":"8","author":"Kosilov","year":"2020","journal-title":"Prostate Int [Internet]"},{"issue":"3","key":"10.1016\/j.prnil.2022.06.002_bib13","article-title":"Human type 3 5\u03b1-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride","volume":"2","author":"Yamana","year":"2010","journal-title":"Horm Mol Biol Clin Invest [Internet]"},{"issue":"3","key":"10.1016\/j.prnil.2022.06.002_bib14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0090-4295(98)00540-8","article-title":"Effects of finasteride in patients with inflammatory chronic pelvic pain syndrome: a double-blind, placebo-controlled, pilot study","volume":"53","author":"Leskinen","year":"1999","journal-title":"Urology [Internet]"},{"issue":"5","key":"10.1016\/j.prnil.2022.06.002_bib15","doi-asserted-by":"crossref","first-page":"306","DOI":"10.5489\/cuaj.686","article-title":"Prostatitis","volume":"5","author":"Nickel","year":"2011","journal-title":"Can Urol Assoc J [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib16","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/00365599709070335","article-title":"Chronic prostatic pain: a new treatment option with Finasteride?","volume":"31","author":"Holm","year":"1997","journal-title":"Scand J Urol Nephrol [Internet]"},{"issue":"2","key":"10.1016\/j.prnil.2022.06.002_bib17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0022-5347(05)68562-X","article-title":"The national institutes of health chronic prostatitis symptom index: development and validation of a new outcome measure","volume":"162","author":"Litwin","year":"1999","journal-title":"J Urol [Internet]"},{"issue":"6","key":"10.1016\/j.prnil.2022.06.002_bib18","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1016\/j.juro.2010.08.025","article-title":"Use of the UPOINT chronic prostatitis\/chronic pelvic pain syndrome classification in European Patient Cohorts: sexual function domain improves correlations","volume":"184","author":"Magri","year":"2010","journal-title":"J Urol [Internet]"},{"issue":"7","key":"10.1016\/j.prnil.2022.06.002_bib19","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/j.1464-410X.2003.04766.x","article-title":"A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis)","volume":"93","author":"Nickel","year":"2004","journal-title":"BJU Int [Internet]"},{"issue":"6","key":"10.1016\/j.prnil.2022.06.002_bib20","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/S0090-4295(96)00038-6","article-title":"Etiology of voiding dysfunction in men less than 50 years of age","volume":"47","author":"Kaplan","year":"1996","journal-title":"Urology [Internet]"},{"issue":"6","key":"10.1016\/j.prnil.2022.06.002_bib21","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1464-410X.1982.tb13635.x","article-title":"Intra-prostatic urinary reflux: an aetiological factor in Abacterial Prostatitis","volume":"54","author":"Kirby","year":"1982","journal-title":"Br J Urol [Internet]"},{"issue":"1","key":"10.1016\/j.prnil.2022.06.002_bib22","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0022-5347(05)65399-2","article-title":"The chronic prostatitis-chronic pelvic pain syndrome can be characterized by prostatic tissue pressure measurements","volume":"167","author":"Mehik","year":"2002","journal-title":"J Urol [Internet]"},{"issue":"4","key":"10.1016\/j.prnil.2022.06.002_bib23","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/bju.14988","article-title":"Pharmacological interventions for treating chronic prostatitis\/chronic pelvic pain syndrome: a Cochrane systematic review","volume":"125","author":"Franco","year":"2020","journal-title":"BJU Int [Internet]"}],"container-title":["Prostate International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2287888222000368?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2287888222000368?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:01:53Z","timestamp":1762419713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2287888222000368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S2287888222000368"],"URL":"https:\/\/doi.org\/10.1016\/j.prnil.2022.06.002","relation":{},"ISSN":["2287-8882"],"issn-type":[{"value":"2287-8882","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short course of dutasteride in treatment of a refractory category IIIB chronic prostatitis (A placebo-controlled study)","name":"articletitle","label":"Article Title"},{"value":"Prostate International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prnil.2022.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Asian Pacific Prostate Society. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}