{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:41:49Z","timestamp":1768455709203,"version":"3.49.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","prosdent.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Prosthetic Dentistry"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.prosdent.2020.02.031","type":"journal-article","created":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T07:47:15Z","timestamp":1590738435000},"page":"767-771","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effectiveness of oral moisturizing gel and flavor on oral moisture and saliva volume: A clinical study"],"prefix":"10.1016","volume":"125","author":[{"given":"Fumi","family":"Mizuhashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Koide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuji","family":"Toya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prosdent.2020.02.031_bib1","doi-asserted-by":"crossref","first-page":"519","DOI":"10.14219\/jada.archive.1985.0384","article-title":"Xerostomia: evaluation of a symptom with increasing significance","volume":"110","author":"Fox","year":"1985","journal-title":"J\u00a0Am Dent Assoc"},{"key":"10.1016\/j.prosdent.2020.02.031_bib2","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0030-4220(88)90268-X","article-title":"Xerostomia. Part 1: relationship to other oral symptoms and salivary gland hypofunction","volume":"66","author":"Sreebny","year":"1988","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.prosdent.2020.02.031_bib3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.14219\/jada.archive.1989.0211","article-title":"The role of saliva in maintaining oral homeostasis","volume":"119","author":"Mandel","year":"1989","journal-title":"J\u00a0Am Dent Assoc"},{"key":"10.1016\/j.prosdent.2020.02.031_bib4","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0022-3913(96)90484-9","article-title":"New design for an artificial saliva reservoir for the mandibular complete denture","volume":"75","author":"Sinclair","year":"1996","journal-title":"J\u00a0Prosthet Dent"},{"key":"10.1016\/j.prosdent.2020.02.031_bib5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1177\/08959374000140010701","article-title":"Xerostomia and hyposalivation","volume":"14","author":"Nederfors","year":"2000","journal-title":"Adv Dent Res"},{"key":"10.1016\/j.prosdent.2020.02.031_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1741-2358.2005.00058.x","article-title":"Issues in the epidemiological investigation of dry mouth","volume":"22","author":"Thomson","year":"2005","journal-title":"Gerodontology"},{"key":"10.1016\/j.prosdent.2020.02.031_bib7","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.tripleo.2003.07.010","article-title":"An update of the etiology and management of xerostomia","volume":"97","author":"Porter","year":"2004","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.prosdent.2020.02.031_bib8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1875-595X.2000.tb00554.x","article-title":"Saliva in health and disease: an appraisal and update","volume":"50","author":"Sreebny","year":"2000","journal-title":"Int Dent J"},{"key":"10.1016\/j.prosdent.2020.02.031_bib9","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1177\/00220345920710070301","article-title":"Clinical criteria for the diagnosis of salivary gland hypofunction","volume":"71","author":"Navazesh","year":"1992","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.prosdent.2020.02.031_bib10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0022-3913(08)60160-2","article-title":"Salivary flow rates measured during radiation therapy in head and neck cancer patients: a pilot study assessing salivary sediment formation","volume":"100","author":"Chambers","year":"2008","journal-title":"J\u00a0Prosthet Dent"},{"key":"10.1016\/j.prosdent.2020.02.031_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1741-2358.2007.00197.x","article-title":"Evaluation of the clinical efficacy of a mouthwash and oral gel containing the antimicrobial proteins lactoperoxidase, lysozyme and lactoferrin in elderly patients with dry mouth -a pilot study","volume":"25","author":"Gil-Montoya","year":"2008","journal-title":"Gerodontology"},{"key":"10.1016\/j.prosdent.2020.02.031_bib12","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/0003-9969(93)90167-K","article-title":"The fungicidal effect of human lactoferrin on candida albicans and candida krusei","volume":"38","author":"Nikawa","year":"1993","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.prosdent.2020.02.031_bib13","first-page":"39","article-title":"Subjective assessment of a new moisturizing mouthwash for the symptomatic management of dry mouth","volume":"17","author":"Shirodaria","year":"2006","journal-title":"J\u00a0Clin Dent"},{"key":"10.1016\/j.prosdent.2020.02.031_bib14","first-page":"45","article-title":"Subjective assessment of a new moisturizing mouth spray for the symptomatic relief of dry mouth","volume":"17","author":"Shirodaria","year":"2006","journal-title":"J\u00a0Clin Dent"},{"key":"10.1016\/j.prosdent.2020.02.031_bib15","first-page":"1429","article-title":"Efficacy of the bioxtra dry mouth care system in the treatment of radiotherapy-induced xerostomia","volume":"15","author":"Dirix","year":"2007","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.prosdent.2020.02.031_bib16","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.oooo.2014.12.005","article-title":"Efficacy and safety of a new oral saliva equivalent in the management of xerostomia: a national, multicenter, randomized study","volume":"119","author":"Salom","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.prosdent.2020.02.031_bib17","first-page":"197","article-title":"Salivary lysozyme, lactoferrin and peroxidases: antibacterial effects on cariogenic bacteria and clinical applications in preventive dentistry","volume":"87","author":"Tenovuo","year":"1991","journal-title":"Proc Finn Dent Soc"},{"key":"10.1016\/j.prosdent.2020.02.031_bib18","series-title":"Gustatory-salivary reflex in the rabbit. Food intake and chemical senses","first-page":"211","author":"Yamamoto","year":"1977"},{"key":"10.1016\/j.prosdent.2020.02.031_bib19","series-title":"Secretory mechanism of the digestive glands","first-page":"591","author":"Babkin","year":"1950"},{"key":"10.1016\/j.prosdent.2020.02.031_bib20","doi-asserted-by":"crossref","first-page":"214","DOI":"10.2186\/prp.5.214","article-title":"Clinical usefulness of an oral moisture checking device (mucus)","volume":"5","author":"Takahashi","year":"2006","journal-title":"Prosthodont Res Pract"},{"key":"10.1016\/j.prosdent.2020.02.031_bib21","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2186\/prp.7.168","article-title":"Study on the measurement condition of oral moisture checking device (mucus)","volume":"7","author":"Takahashi","year":"2008","journal-title":"Prosthodont Res Pract"},{"key":"10.1016\/j.prosdent.2020.02.031_bib22","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2186\/prp.5.26","article-title":"Oral dryness examinations: use of an oral moisture checking device and a modified cotton method","volume":"5","author":"Takahashi","year":"2006","journal-title":"Prosthodont Res Pract"}],"container-title":["The Journal of Prosthetic Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022391320302122?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022391320302122?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T10:55:28Z","timestamp":1758365728000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022391320302122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S0022391320302122"],"URL":"https:\/\/doi.org\/10.1016\/j.prosdent.2020.02.031","relation":{},"ISSN":["0022-3913"],"issn-type":[{"value":"0022-3913","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of oral moisturizing gel and flavor on oral moisture and saliva volume: A clinical study","name":"articletitle","label":"Article Title"},{"value":"The Journal of Prosthetic Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prosdent.2020.02.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the Editorial Council for The Journal of Prosthetic Dentistry.","name":"copyright","label":"Copyright"}]}}