{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:31:32Z","timestamp":1791912692323,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005762","name":"National Taiwan University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","prosdent.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Prosthetic Dentistry"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.prosdent.2023.11.002","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T23:55:13Z","timestamp":1701302113000},"page":"1504.e1-1504.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["A cross-sectional study for prevalence and risk factors of peri-implant marginal bone loss"],"prefix":"10.1016","volume":"133","author":[{"given":"Jui-Sheng","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke-Chun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Chih","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Ying","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Lin","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Ju","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny Zwei-Chieng","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prosdent.2023.11.002_bib1","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1177\/0022034518792567","article-title":"Trends in dental implant use in the U.S., 1999-2016, and projections to 2026","volume":"97","author":"Elani","year":"2018","journal-title":"J Dent Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ijom.2014.10.023","article-title":"Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: A systematic review","volume":"44","author":"Moraschini","year":"2015","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"Suppl 20","key":"10.1016\/j.prosdent.2023.11.002_bib3","article-title":"Peri-implantitis","volume":"45","author":"Schwarz","year":"2018","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib4","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1600-0501.2012.02555.x","article-title":"Peri-implant tissue destruction. The third EAO consensus conference 2012","volume":"23","author":"Klinge","year":"2012","journal-title":"Clin Oral Implants Res"},{"issue":"Suppl 16","key":"10.1016\/j.prosdent.2023.11.002_bib5","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/clr.13287","article-title":"Clinical outcomes of peri-implantitis treatment and supportive care: A systematic review","volume":"29","author":"Roccuzzo","year":"2018","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/prd.12417","article-title":"Surgical therapy of peri-implantitis","volume":"88","author":"Schwarz","year":"2022","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.prosdent.2023.11.002_bib7","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00784-013-1134-9","article-title":"Oral rehabilitation with dental implants in irradiated patients: A meta-analysis on implant survival","volume":"18","author":"Schiegnitz","year":"2014","journal-title":"Clin Oral Investig"},{"issue":"Suppl 21","key":"10.1016\/j.prosdent.2023.11.002_bib8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/clr.13827","article-title":"Peri-implantitis: Summary and consensus statements of group 3. The 6th EAO Consensus Conference 2021","volume":"32","author":"Schwarz","year":"2021","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib9","first-page":"75","article-title":"Cross-sectional study on the prevalence and risk indicators of peri-implant diseases","volume":"8","author":"Konstantinidis","year":"2015","journal-title":"Eur J Oral Implanto"},{"issue":"Suppl 16","key":"10.1016\/j.prosdent.2023.11.002_bib10","first-page":"S158","article-title":"Peri-implant health and disease. A systematic review of current epidemiology","volume":"42","author":"Derks","year":"2015","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib11","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/jre.12562","article-title":"Epidemiology and risk factors of peri-implantitis: A systematic review","volume":"53","author":"Dreyer","year":"2018","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib12","doi-asserted-by":"crossref","DOI":"10.5037\/jomr.2016.7305","article-title":"General diseases influence on peri-implantitis development: A systematic review","volume":"7","author":"Guobis","year":"2016","journal-title":"J Oral Maxillofac Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib13","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1111\/cid.12427","article-title":"Peri-implantitis\": A complication of a foreign body or a man-made \"Disease\". Facts and fiction","volume":"18","author":"Albrektsson","year":"2016","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib14","first-page":"e1045","article-title":"Influence of marginal bone loss on peri-implantitis: Systematic review of literature","volume":"11","author":"Carrasco-Garc\u00eda","year":"2019","journal-title":"J Clin Exp Dent"},{"key":"10.1016\/j.prosdent.2023.11.002_bib15","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1902\/jop.2015.150229","article-title":"Relationship between osteoporosis and marginal bone loss in osseointegrated implants: A 2-year retrospective study","volume":"87","author":"Corcuera-Flores","year":"2016","journal-title":"J Periodontol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib16","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1902\/jop.2012.120555","article-title":"Treatment outcome in patients with peri-implantitis in a periodontal clinic: A retrospective study","volume":"84","author":"Lagervall","year":"2013","journal-title":"J Periodontol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/0022034515608832","article-title":"Effectiveness of implant therapy analyzed in a Swedish population: Prevalence of peri-implantitis","volume":"95","author":"Derks","year":"2016","journal-title":"J Dent Res"},{"issue":"Suppl","key":"10.1016\/j.prosdent.2023.11.002_bib18","first-page":"S91","article-title":"Identifying occlusal overload and how to deal with it to avoid marginal bone loss around implants","volume":"5","author":"Fu","year":"2012","journal-title":"Eur J Oral Implantol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib19","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/odi.12762","article-title":"The medically compromised patient: Are dental implants a feasible option?","volume":"24","author":"Vissink","year":"2018","journal-title":"Oral Dis"},{"key":"10.1016\/j.prosdent.2023.11.002_bib20","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/JPER.18-0236","article-title":"Retrospective cohort study of 4,591 dental implants: Analysis of risk indicators for bone loss and prevalence of peri-implant mucositis and peri-implantitis","volume":"90","author":"French","year":"2019","journal-title":"J Periodontol"},{"issue":"Suppl 12","key":"10.1016\/j.prosdent.2023.11.002_bib21","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1600-051X.2011.01837.x","article-title":"Clinical research on peri-implant diseases: Consensus report of Working Group 4","volume":"39","author":"Sanz","year":"2012","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.prosdent.2023.11.002_bib22","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/clr.12772","article-title":"Risk indicators for peri-implantitis. A cross-sectional study with 916 implants","volume":"28","author":"Dalago","year":"2017","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib23","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/clr.13684","article-title":"Prevalence and risk\/protective indicators of peri-implant diseases: A university-representative cross-sectional study","volume":"32","author":"Romandini","year":"2021","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib24","doi-asserted-by":"crossref","first-page":"3527872","DOI":"10.1155\/2019\/3527872","article-title":"An 11-year retrospective research study of the predictive factors of peri-implantitis and implant failure: Analytic-multicentric study of 1279 implants in Peru","volume":"2019","author":"Mayta-Tovalino","year":"2019","journal-title":"Int J Dent"},{"key":"10.1016\/j.prosdent.2023.11.002_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.11607\/jomi.4149","article-title":"Prevalence of peri-implantitis in medically compromised patients and smokers: A systematic review","volume":"31","author":"Turri","year":"2016","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.1016\/j.prosdent.2023.11.002_bib26","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1016\/j.biopha.2018.11.032","article-title":"Metformin; An old antidiabetic drug with new potentials in bone disorders","volume":"109","author":"Bahrambeigi","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.prosdent.2023.11.002_bib27","article-title":"Metformin-incorporated gelatin\/nano-hydroxyapatite scaffolds promotes bone regeneration in critical size rat alveolar bone defect model","volume":"23","author":"Fang","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.prosdent.2023.11.002_bib28","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/j.joen.2018.08.002","article-title":"Metformin ameliorates periapical lesions through suppression of hypoxia-induced apoptosis of osteoblasts","volume":"44","author":"Lai","year":"2018","journal-title":"J Endod"},{"key":"10.1016\/j.prosdent.2023.11.002_bib29","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.prosdent.2018.01.019","article-title":"Prognosis of dental implants in patients with low bone density: A systematic review and meta-analysis","volume":"120","author":"Radi","year":"2018","journal-title":"J Prosthet Dent"},{"key":"10.1016\/j.prosdent.2023.11.002_bib30","first-page":"255","article-title":"Systemic risk indicators for peri-implant diseases in individuals with implant-supported fixed prostheses: A cross-sectional study","volume":"13","author":"Alves","year":"2020","journal-title":"Int J Oral Implantol ((Berl))"},{"key":"10.1016\/j.prosdent.2023.11.002_bib31","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/clr.12766","article-title":"An open, prospective, non-randomized, controlled, multicentre study to evaluate the clinical outcome of implant treatment in women over 60 years of age with osteoporosis\/osteopenia: 1-year results","volume":"28","author":"Temmerman","year":"2017","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib32","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/cid.12493","article-title":"Does osteoporosis influence the marginal peri-implant bone level in female patients? A cross-sectional study in a matched collective.","volume":"19","author":"Wagner","year":"2017","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib33","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/clr.12907","article-title":"Bone stability around implants in elderly patients with reduced bone mineral density - a prospective study on mandibular overdentures","volume":"28","author":"Chow","year":"2017","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.prosdent.2023.11.002_bib34","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1007\/s00198-019-05257-3","article-title":"Effects of anti-resorptive drugs on implant survival and peri-implantitis in patients with existing osseointegrated dental implants: A retrospective cohort study","volume":"31","author":"Kim","year":"2020","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.prosdent.2023.11.002_bib35","first-page":"217","article-title":"Retrospective long-term evaluation of dental implants in totally and partially edentulous patients: part II: periimplant disease","volume":"24","author":"Trullenque-Eriksson","year":"2015","journal-title":"Implant Dent"},{"key":"10.1016\/j.prosdent.2023.11.002_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10143043","article-title":"Efficacy and safety of postmenopausal osteoporosis treatments: A systematic review and network meta-analysis of randomized controlled trials","volume":"10","author":"Lin","year":"2021","journal-title":"J Clin Med"}],"container-title":["The Journal of Prosthetic Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022391323007229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022391323007229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:04:17Z","timestamp":1749513857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022391323007229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0022391323007229"],"URL":"https:\/\/doi.org\/10.1016\/j.prosdent.2023.11.002","relation":{},"ISSN":["0022-3913"],"issn-type":[{"value":"0022-3913","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A cross-sectional study for prevalence and risk factors of peri-implant marginal bone loss","name":"articletitle","label":"Article Title"},{"value":"The Journal of Prosthetic Dentistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prosdent.2023.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2025 by the Editorial Council of The Journal of Prosthetic Dentistry. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}