{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:12:00Z","timestamp":1767924720825,"version":"3.49.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prostaglandins & Other Lipid Mediators"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.prostaglandins.2012.07.001","type":"journal-article","created":{"date-parts":[[2012,7,16]],"date-time":"2012-07-16T06:16:10Z","timestamp":1342419370000},"page":"45-50","source":"Crossref","is-referenced-by-count":6,"title":["Tumor necrosis factor-alpha induces renal cyclooxygenase-2 expression in response to hypercalcemia"],"prefix":"10.1016","volume":"99","author":[{"given":"Sailaja","family":"Battula","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoujin","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulina L.","family":"Pedraza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles T.","family":"Stier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas R.","family":"Ferreri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.prostaglandins.2012.07.001_bib0005","doi-asserted-by":"crossref","first-page":"F94","DOI":"10.1152\/ajprenal.00650.2010","article-title":"Tumor necrosis factor-alpha is an endogenous inhibitor of Na+\u2013K+\u20132Cl\u2212 cotransporter (NKCC2) isoform A in the thick ascending limb","volume":"301","author":"Battula","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"issue":"4","key":"10.1016\/j.prostaglandins.2012.07.001_bib0010","doi-asserted-by":"crossref","first-page":"F1082","DOI":"10.1152\/ajprenal.90316.2008","article-title":"Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE2 production: functional significance","volume":"295","author":"Abdullah","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"issue":"4","key":"10.1016\/j.prostaglandins.2012.07.001_bib0015","doi-asserted-by":"crossref","first-page":"F658","DOI":"10.1152\/ajprenal.2001.281.4.F658","article-title":"CaR-mediated COX-2 expression in primary cultured mTAL cells","volume":"281","author":"Wang","year":"2001","journal-title":"Am J Physiol Renal Physiol"},{"issue":"5","key":"10.1016\/j.prostaglandins.2012.07.001_bib0020","doi-asserted-by":"crossref","first-page":"F963","DOI":"10.1152\/ajprenal.00108.2002","article-title":"Calcium-sensing receptor-mediated TNF production in medullary thick ascending limb cells","volume":"283","author":"Wang","year":"2002","journal-title":"Am J Physiol Renal Physiol"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0025","doi-asserted-by":"crossref","first-page":"F1836","DOI":"10.1152\/ajprenal.90297.2008","article-title":"Tumor necrosis factor-alpha induces renal vasoconstriction as well as natriuresis in mice","volume":"295","author":"Shahid","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"issue":"1","key":"10.1016\/j.prostaglandins.2012.07.001_bib0030","doi-asserted-by":"crossref","first-page":"F217","DOI":"10.1152\/ajprenal.00611.2009","article-title":"Involvement of tumor necrosis factor-alpha in natriuretic response to systemic infusion of nitric oxide synthase inhibitor in anesthetized mice","volume":"299","author":"Shahid","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"issue":"5","key":"10.1016\/j.prostaglandins.2012.07.001_bib0035","doi-asserted-by":"crossref","first-page":"F1110","DOI":"10.1152\/ajprenal.00223.2005","article-title":"NFAT regulates calcium-sensing receptor-mediated TNF production","volume":"290","author":"Abdullah","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0040","doi-asserted-by":"crossref","first-page":"F1494","DOI":"10.1152\/ajprenal.90436.2008","article-title":"Expression and function of NFAT5 in medullary thick ascending limb (mTAL) cells","volume":"296","author":"Hao","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.prostaglandins.2012.07.001_bib0045","first-page":"257","article-title":"The calcium-sensing receptor (CaR) permits Ca2+ to function as a versatile extracellular first messenger","volume":"53","author":"Brown","year":"1998","journal-title":"Recent Prog Horm Res"},{"issue":"3","key":"10.1016\/j.prostaglandins.2012.07.001_bib0050","doi-asserted-by":"crossref","first-page":"F720","DOI":"10.1152\/ajprenal.00164.2009","article-title":"The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormone","volume":"297","author":"Egbuna","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"issue":"4","key":"10.1016\/j.prostaglandins.2012.07.001_bib0055","doi-asserted-by":"crossref","first-page":"E915","DOI":"10.1152\/ajpendo.00315.2009","article-title":"The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion","volume":"297","author":"Kantham","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.prostaglandins.2012.07.001_bib0060","doi-asserted-by":"crossref","first-page":"F485","DOI":"10.1152\/ajprenal.00608.2009","article-title":"Physiology and pathophysiology of the calcium-sensing receptor in the kidney","volume":"298","author":"Riccardi","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"issue":"5","key":"10.1016\/j.prostaglandins.2012.07.001_bib0065","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/HYPERTENSIONAHA.108.120246","article-title":"Sodium reabsorption in the thick ascending limb in relation to blood pressure: a clinical perspective","volume":"57","author":"Jung","year":"2011","journal-title":"Hypertension"},{"issue":"3 Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0070","first-page":"F360","article-title":"Cyclooxygenase-2 expression and function in the medullary thick ascending limb","volume":"277","author":"Ferreri","year":"1999","journal-title":"Am J Physiol"},{"issue":"6012","key":"10.1016\/j.prostaglandins.2012.07.001_bib0075","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/314620a0","article-title":"Renal cytochrome P450-related arachidonate metabolite inhibits (Na++K+)ATPase","volume":"314","author":"Schwartzman","year":"1985","journal-title":"Nature"},{"issue":"3 Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0080","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1161\/01.HYP.30.3.687","article-title":"Renal identification of cyclooxygenase-2 in a subset of thick ascending limb cells","volume":"30","author":"Vio","year":"1997","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.prostaglandins.2012.07.001_bib0085","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1681\/ASN.V124649","article-title":"Induction of cyclooxygenase-2 in thick ascending limb cells by adrenalectomy","volume":"12","author":"Vio","year":"2001","journal-title":"J Am Soc Nephrol"},{"issue":"7","key":"10.1016\/j.prostaglandins.2012.07.001_bib0090","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1172\/JCI5505","article-title":"Angiotensin II attenuates renal cortical cyclooxygenase-2 expression","volume":"103","author":"Cheng","year":"1999","journal-title":"J Clin Invest"},{"issue":"3 Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0095","first-page":"F481","article-title":"Regulation of cyclooxygenase expression in the kidney by dietary salt intake","volume":"274","author":"Yang","year":"1998","journal-title":"Am J Physiol"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0100","doi-asserted-by":"crossref","first-page":"F1068","DOI":"10.1152\/ajprenal.00434.2002","article-title":"Increased expression of cyclooxygenase-1 and -2 in the diabetic rat renal medulla","volume":"285","author":"Nasrallah","year":"2003","journal-title":"Am J Physiol Renal Physiol"},{"issue":"8","key":"10.1016\/j.prostaglandins.2012.07.001_bib0105","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1172\/JCI119725","article-title":"Hypercalcemia stimulates expression of intrarenal phospholipase A2 and prostaglandin H synthase-2 in rats. Role of angiotensin II AT1 receptors","volume":"100","author":"Mangat","year":"1997","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0110","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1172\/JCI116473","article-title":"Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia","volume":"91","author":"Peterson","year":"1993","journal-title":"J Clin Invest"},{"issue":"5 Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0115","first-page":"F978","article-title":"Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats","volume":"274","author":"Sands","year":"1998","journal-title":"Am J Physiol"},{"issue":"3","key":"10.1016\/j.prostaglandins.2012.07.001_bib0120","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1046\/j.1523-1755.2003.00801.x","article-title":"Increased endothelin-1 expression in the kidney in hypercalcemic rats","volume":"63","author":"Shiraishi","year":"2003","journal-title":"Kidney Int"},{"issue":"1 Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0125","first-page":"F122","article-title":"Vitamin D-induced chronic hypercalcemia inhibits thick ascending limb NaCl reabsorption in vivo","volume":"259","author":"Peterson","year":"1990","journal-title":"Am J Physiol"},{"issue":"7","key":"10.1016\/j.prostaglandins.2012.07.001_bib0130","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1172\/JCI17416","article-title":"The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone","volume":"111","author":"Kos","year":"2003","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0135","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1172\/JCI119299","article-title":"Apical extracellular calcium\/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct","volume":"99","author":"Sands","year":"1997","journal-title":"J Clin Invest"},{"issue":"5","key":"10.1016\/j.prostaglandins.2012.07.001_bib0140","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1038\/ki.1989.98","article-title":"Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide","volume":"35","author":"Baud","year":"1989","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.prostaglandins.2012.07.001_bib0145","first-page":"1444","article-title":"Tumor necrosis factor-alpha is expressed by glomerular visceral epithelial cells in human membranous nephropathy","volume":"146","author":"Neale","year":"1995","journal-title":"Am J Pathol"},{"issue":"2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0150","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/ki.1991.201","article-title":"Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha","volume":"40","author":"Jevnikar","year":"1991","journal-title":"Kidney Int"},{"issue":"1","key":"10.1016\/j.prostaglandins.2012.07.001_bib0155","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/ki.1994.250","article-title":"TNF production by the medullary thick ascending limb of Henle's loop","volume":"46","author":"Macica","year":"1994","journal-title":"Kidney Int"},{"issue":"1 Pt 1","key":"10.1016\/j.prostaglandins.2012.07.001_bib0160","doi-asserted-by":"crossref","first-page":"C354","DOI":"10.1152\/ajpcell.1996.271.1.C354","article-title":"Prostaglandin E2 inhibits Na\u2013K\u20132Cl cotransport in medullary thick ascending limb cells","volume":"271","author":"Kaji","year":"1996","journal-title":"Am J Physiol"},{"issue":"2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0165","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1172\/JCI109487","article-title":"Effect of prostaglandin E2 on chloride transport across the rabbit thick ascending limb of Henle. Selective inhibitions of the medullary portion","volume":"64","author":"Stokes","year":"1979","journal-title":"J Clin Invest"},{"issue":"Pt 2","key":"10.1016\/j.prostaglandins.2012.07.001_bib0170","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1242\/jeb.200.2.295","article-title":"Role of the Ca(2+)-sensing receptor in divalent mineral ion homeostasis","volume":"200","author":"Hebert","year":"1997","journal-title":"J Exp Biol"},{"issue":"3","key":"10.1016\/j.prostaglandins.2012.07.001_bib0175","first-page":"F224","article-title":"Prostaglandin-dependent polyuria in hypercalcemia","volume":"241","author":"Serros","year":"1981","journal-title":"Am J Physiol"},{"issue":"91","key":"10.1016\/j.prostaglandins.2012.07.001_bib0180","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1111\/j.1523-1755.2004.09105.x","article-title":"Calcium and salinity sensing by the thick ascending limb: a journey from mammals to fish and back again","author":"Hebert","year":"2004","journal-title":"Kidney Int Suppl"}],"container-title":["Prostaglandins & Other Lipid Mediators"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098882312000731?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098882312000731?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T11:16:39Z","timestamp":1642763799000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098882312000731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":36,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S1098882312000731"],"URL":"https:\/\/doi.org\/10.1016\/j.prostaglandins.2012.07.001","relation":{},"ISSN":["1098-8823"],"issn-type":[{"value":"1098-8823","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}