{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:05:40Z","timestamp":1791828340351,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.prp.2012.01.004","type":"journal-article","created":{"date-parts":[[2012,2,24]],"date-time":"2012-02-24T03:09:34Z","timestamp":1330052974000},"page":"245-249","source":"Crossref","is-referenced-by-count":22,"title":["Primary primitive neuroectodermal tumor of the cervix confirmed with molecular analysis in a 23-year-old woman: A case report"],"prefix":"10.1016","volume":"208","author":[{"given":"Sophia","family":"Masoura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anargyros","family":"Kourtis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Kalogiannidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassiliki","family":"Kotoula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftherios","family":"Anagnostou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stamatia","family":"Angelidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodoros","family":"Agorastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2012.01.004_bib0005","doi-asserted-by":"crossref","first-page":"488","DOI":"10.2350\/06-01-0007.1","article-title":"Ewing sarcoma family of tumors in unusual sites: confirmation by rt-PCR","volume":"9","author":"Ahmed","year":"2006","journal-title":"Pediatr. Dev. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0010","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/08880010500506297","article-title":"Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report","volume":"23","author":"Athanassiadou","year":"2006","journal-title":"Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0015","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s11060-009-0014-2","article-title":"Amplification and overexpression of KIT, PDGFRA, and VEGFR2 in medulloblastomas and primitive neuroectodermal tumors","volume":"97","author":"Blom","year":"2010","journal-title":"J. Neurooncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0020","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/pbc.21132","article-title":"A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: a Children's Oncology Group study","volume":"50","author":"Bond","year":"2008","journal-title":"Pediatr. Blood Cancer"},{"key":"10.1016\/j.prp.2012.01.004_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/modpathol.3800486","article-title":"Molecular diagnosis of Ewing sarcoma\/primitive neuroectodermal tumor in routinely processed tissue: a comparison of two FISH strategies and RT-PCR in malignant round cell tumors","volume":"19","author":"Bridge","year":"2006","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0030","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00004347-199801000-00015","article-title":"Primary endocervical extraosseous Ewing's sarcoma\/PNET","volume":"17","author":"Cenacchi","year":"1998","journal-title":"Int. J. Gynecol. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0035","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00043426-200105000-00009","article-title":"Molecular confirmation of Ewing sarcoma","volume":"23","author":"Dagher","year":"2001","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0040","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0165-4608(96)00326-3","article-title":"Multiple chromosomal mechanisms generate an EWS\/FLI1 or an EWS\/ERG fusion gene in Ewing tumors","volume":"97","author":"Desmaze","year":"1997","journal-title":"Cancer Genet. Cytogenet."},{"key":"10.1016\/j.prp.2012.01.004_bib0045","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.prp.2006.12.005","article-title":"Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarcomas","volume":"203","author":"Do","year":"2007","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.prp.2012.01.004_bib0050","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/PAS.0b013e318093e421","article-title":"Uterine tumors with neuroectodermal differentiation: a series of 17 cases and review of the literature","volume":"32","author":"Euscher","year":"2008","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0055","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1056\/NEJMoa020890","article-title":"Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone","volume":"348","author":"Grier","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.prp.2012.01.004_bib0060","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/1097-0142(197310)32:4<890::AID-CNCR2820320421>3.0.CO;2-O","article-title":"Primitive neuroectodermal tumors of the brain in children","volume":"32","author":"Hart","year":"1973","journal-title":"Cancer"},{"key":"10.1016\/j.prp.2012.01.004_bib0065","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0090-4295(94)80024-3","article-title":"Primary neuroectodermal tumor of the retroperitoneal cavity","volume":"44","author":"Horigushi","year":"1994","journal-title":"Urology"},{"key":"10.1016\/j.prp.2012.01.004_bib0070","first-page":"227","article-title":"Primitive neuroectodermal tumor of the cervix uteri. A case report","volume":"142","author":"Horn","year":"1997","journal-title":"Gen. Diagn. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0075","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1158\/0008-5472.CAN-04-2857","article-title":"EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors","volume":"65","author":"Hu-Lieskovan","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2012.01.004_bib0080","first-page":"416","article-title":"Molecular classification of soft tissue sarcomas and its clinical applications","volume":"3","author":"Jain","year":"2010","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0085","doi-asserted-by":"crossref","first-page":"e5415","DOI":"10.1371\/journal.pone.0005415","article-title":"A molecular function map of Ewing's sarcoma","volume":"4","author":"Kauer","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.prp.2012.01.004_bib0090","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1097\/00000478-199308000-00002","article-title":"Primary neuroectodermal tumors of the ovary a report of 25 cases","volume":"17","author":"Klieman","year":"1993","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0095","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00428-004-0994-4","article-title":"Synovial sarcoma of the heart","volume":"444","author":"Koletsa","year":"2004","journal-title":"Virchows Arch."},{"key":"10.1016\/j.prp.2012.01.004_bib0100","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1006\/geno.1999.5919","article-title":"Cryptic exons as a source of increased diversity of Ewing tumor-associated EWS-FLI1 chimeric products","volume":"60","author":"Kovar","year":"1999","journal-title":"Genomics"},{"key":"10.1016\/j.prp.2012.01.004_bib0105","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.5858\/2006-130-1199-MDOS","article-title":"Molecular diagnosis of sarcomas: chromosomal translocations in sarcomas","volume":"130","author":"Lazar","year":"2006","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.prp.2012.01.004_bib0110","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/modpathol.3800755","article-title":"Differentiating Ewing's sarcoma from other round blue cell tumors using a RT-PCR translocation panel on formalin-fixed paraffin-embedded tissues","volume":"20","author":"Lewis","year":"2007","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0115","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1053\/adpa.2002.35739","article-title":"Primitive neuroectodermal tumor of the cervix: a clinicopathological and immunohistochemical study of two cases","volume":"6","author":"Malpica","year":"2002","journal-title":"Ann. Diagn. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0120","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1136\/jcp.2006.040931","article-title":"Ewing family of tumours involving the vulva and vagina: report of a series of four cases","volume":"60","author":"McCluggage","year":"2007","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.prp.2012.01.004_bib0125","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/PL00008201","article-title":"Peripheral primitive neuroectodermal tumour of the cervix","volume":"436","author":"Pauwels","year":"2000","journal-title":"Virchows Arch."},{"key":"10.1016\/j.prp.2012.01.004_bib0130","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/labinvest.3780299","article-title":"A multiplex real-time PCR assay for the detection of gene fusions observed in solid tumors","volume":"81","author":"Peter","year":"2001","journal-title":"Lab. Invest."},{"key":"10.1016\/j.prp.2012.01.004_bib0135","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0959-8049(02)00500-2","article-title":"A systematic review of molecular and biological markers in tumours of the Ewing's sarcoma family","volume":"39","author":"Riley","year":"2003","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.prp.2012.01.004_bib0140","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1620\/tjem.180.187","article-title":"Peripheral neuroepithelioma (peripheral primitive neuroectodermal tumor) of the uterine cervix","volume":"180","author":"Sato","year":"1996","journal-title":"Tohoku J. Exp. Med."},{"key":"10.1016\/j.prp.2012.01.004_bib0145","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1006\/gyno.1994.1204","article-title":"Case report: primitive neuroectodermal tumor of the vulva","volume":"54","author":"Scherr","year":"1994","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0150","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1200\/JCO.2003.11.111","article-title":"C-kit receptor expression in Ewing's sarcoma: lack of prognostic value but therapeutic targeting opportunities in appropriate conditions","volume":"21","author":"Scotlandi","year":"2003","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0155","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.ygyno.2005.05.020","article-title":"Primitive neuroectodermal tumor of the cervix uteri: a case report changing concepts in therapy","volume":"98","author":"Snijders-Keilholz","year":"2005","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.prp.2012.01.004_bib0160","doi-asserted-by":"crossref","first-page":"8213","DOI":"10.1158\/0008-5472.CAN-03-4059","article-title":"DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets","volume":"64","author":"Staege","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2012.01.004_bib0165","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1055\/s-2004-832338","article-title":"Identification of various exon combinations of the ews\/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue \u2013 a report by the CWS-study group","volume":"216","author":"Stegmaier","year":"2004","journal-title":"Klin. Padiatr."},{"key":"10.1016\/j.prp.2012.01.004_bib0170","doi-asserted-by":"crossref","first-page":"6482","DOI":"10.1038\/sj.onc.1204042","article-title":"The role of Fli-1 in normal cell function and malignant transformation","volume":"19","author":"Truong","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.prp.2012.01.004_bib0175","doi-asserted-by":"crossref","unstructured":"A.S. Tsao, L.M. Roth, A. Sandler, J.A. Hurteau, Case report. Cervical primitive neuroectodermal tumor, Gynecol. Oncol. 83 (2001) 138\u2013142.","DOI":"10.1006\/gyno.2001.6339"},{"key":"10.1016\/j.prp.2012.01.004_bib0180","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1200\/JCO.2009.24.5845","article-title":"Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group","volume":"28","author":"van Doorninck","year":"2010","journal-title":"J. Clin. Oncol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033812000313?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033812000313?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T19:07:12Z","timestamp":1640891232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033812000313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0344033812000313"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2012.01.004","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}