{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:06:40Z","timestamp":1791331600359,"version":"4.3.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003645","name":"National Cancer Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["221S0001"],"award-info":[{"award-number":["221S0001"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23120201"],"award-info":[{"award-number":["23120201"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["10103838"],"award-info":[{"award-number":["10103838"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.prp.2014.10.013","type":"journal-article","created":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T20:24:55Z","timestamp":1416169495000},"page":"404-408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["NSD3-NUT-expressing midline carcinoma of the lung: First characterization of primary cancer tissue"],"prefix":"10.1016","volume":"211","author":[{"given":"Shioto","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuya","family":"Kurabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ippei","family":"Ohnishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumasa","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichiro","family":"Aoshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Naito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumihiko","family":"Tanioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Sugimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2014.10.013_bib0005","doi-asserted-by":"crossref","first-page":"5773","DOI":"10.1158\/1078-0432.CCR-12-1153","article-title":"Clinicopathologic features and long-term outcomes of NUT midline carcinoma","volume":"18","author":"Bauer","year":"2012","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.prp.2014.10.013_bib0010","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/PAS.0b013e318254ce54","article-title":"NUT midline carcinomas of the sinonasal tract","volume":"36","author":"Bishop","year":"2012","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0015","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.5858\/arpa.2010-0389-CR","article-title":"Nuclear protein in testis midline carcinomas: a lethal and underrecognized entity","volume":"135","author":"Davis","year":"2011","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.prp.2014.10.013_bib0020","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1097\/PAS.0b013e318258f03b","article-title":"Pathologic characteristics of NUT midline carcinoma arising in the mediastinum","volume":"36","author":"Evans","year":"2012","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0025","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/nature09504","article-title":"Selective inhibition of BET bromodomains","volume":"468","author":"Filippakopoulos","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.prp.2014.10.013_bib0030","first-page":"304","article-title":"BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma","volume":"63","author":"French","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2014.10.013_bib0035","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1200\/JCO.2004.02.107","article-title":"Midline carcinoma of children and young adults with NUT rearrangement","volume":"22","author":"French","year":"2004","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.prp.2014.10.013_bib0040","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.cancergencyto.2010.06.007","article-title":"NUT midline carcinoma","volume":"203","author":"French","year":"2010","journal-title":"Cancer Genet. Cytogenet."},{"key":"10.1016\/j.prp.2014.10.013_bib0045","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev-pathol-011811-132438","article-title":"Pathogenesis of NUT midline carcinoma","volume":"7","author":"French","year":"2012","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0050","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1158\/2159-8290.CD-14-0014","article-title":"NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism","volume":"4","author":"French","year":"2014","journal-title":"Cancer Discov."},{"key":"10.1016\/j.prp.2014.10.013_bib0055","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1097\/PAS.0b013e318198d666","article-title":"Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody","volume":"33","author":"Haack","year":"2009","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0060","first-page":"158","article-title":"Cancers and the NSD family of histone lysine methyltransferases","volume":"1816","author":"Morishita","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.prp.2014.10.013_bib0065","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/JTO.0b013e3182a00f41","article-title":"NUT midline carcinoma: an aggressive intrathoracic neoplasm","volume":"8","author":"Parikh","year":"2013","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.prp.2014.10.013_bib0070","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1158\/0008-5472.CAN-10-3513","article-title":"Differentiation of NUT midline carcinoma by epigenomic reprogramming","volume":"71","author":"Schwartz","year":"2011","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2014.10.013_bib0075","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1097\/PAS.0b013e31815a3900","article-title":"NUT rearrangement in undifferentiated carcinomas of the upper aerodigestive tract","volume":"32","author":"Stelow","year":"2008","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0080","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12105-010-0235-x","article-title":"A review of NUT midline carcinoma","volume":"5","author":"Stelow","year":"2011","journal-title":"Head Neck Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0085","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1093\/carcin\/bgn046","article-title":"Detection of chromosome changes in pathology archives: an application of microwave-assisted fluorescence in situ hybridization to human carcinogenesis studies","volume":"29","author":"Sugimura","year":"2008","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.prp.2014.10.013_bib0090","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/j.1440-1827.2010.02561.x","article-title":"Fluorescence in situ hybridization analysis with a tissue microarray: \u2018FISH and chips\u2019 analysis of pathology archives","volume":"60","author":"Sugimura","year":"2010","journal-title":"Pathol. Int."},{"key":"10.1016\/j.prp.2014.10.013_bib0095","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.prp.2014.01.013","article-title":"A rare Japanese case with a NUT midline carcinoma in the nasal cavity: a case report with immunohistochemical and genetic analyses","volume":"210","author":"Suzuki","year":"2014","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.prp.2014.10.013_bib0100","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/PAS.0b013e31824230a8","article-title":"NUT midline carcinoma: report of 2 cases suggestive of pulmonary origin","volume":"36","author":"Tanaka","year":"2012","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2014.10.013_bib0105","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.cllc.2013.06.012","article-title":"Clinicopathological features in young patients treated for small-cell lung cancer: significance of immunohistological and molecular analyses","volume":"15","author":"Taniyama","year":"2014","journal-title":"Clin. Lung Cancer"},{"key":"10.1016\/j.prp.2014.10.013_bib0110","doi-asserted-by":"crossref","first-page":"9625","DOI":"10.1073\/pnas.0504126102","article-title":"High-resolution genomic profiles of human lung cancer","volume":"102","author":"Tonon","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.prp.2014.10.013_bib0115","article-title":"A case of NUT midline carcinoma with complete response to gemcitabine following cisplatin and docetaxel","author":"Ueki","year":"2013","journal-title":"J. Pediatr. Hematol. Oncol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033814003112?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033814003112?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T06:35:18Z","timestamp":1759732518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033814003112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0344033814003112"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2014.10.013","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NSD3-NUT-expressing midline carcinoma of the lung: First characterization of primary cancer tissue","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2014.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}