{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:23:53Z","timestamp":1770823433100,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.prp.2015.10.009","type":"journal-article","created":{"date-parts":[[2015,10,30]],"date-time":"2015-10-30T22:49:54Z","timestamp":1446245394000},"page":"1034-1039","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?"],"prefix":"10.1016","volume":"211","author":[{"given":"Takashi","family":"Muraki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyoshi","family":"Oota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Yoshizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiho","family":"Asaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Tateishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Otsuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Shingu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisanori","family":"Matoba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shojiro","family":"Ichimata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Itou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiji","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2015.10.009_bib0125","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/00000478-200107000-00014","article-title":"The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncystic carcinoma and ductal adenocarcinoma","volume":"25","author":"L\u00fcttges","year":"2001","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0130","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/gut.2010.210567","article-title":"Prognostic relevance of morphological types of intraductal papillary mucinous neoplasms of the pancreas","volume":"60","author":"Furukawa","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.prp.2015.10.009_bib0135","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.pan.2012.04.004","article-title":"International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas","volume":"12","author":"Tanaka","year":"2012","journal-title":"Pancreatology"},{"key":"10.1016\/j.prp.2015.10.009_bib0140","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/MPA.0b013e31802dea0","article-title":"Pancreatic juice cytology and subclassification of intraductal papillary mucinous neoplasms of the pancreas","volume":"34","author":"Hibi","year":"2007","journal-title":"Pancreas"},{"key":"10.1016\/j.prp.2015.10.009_bib0145","series-title":"WHO Classification of Tumours of the Digestive System","first-page":"304","article-title":"Intraductal neoplasms of the pancreas","author":"Adsay","year":"2010"},{"key":"10.1016\/j.prp.2015.10.009_bib0150","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/hep.21387","article-title":"Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas","volume":"44","author":"Zen","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.prp.2015.10.009_bib0155","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1267\/ahc.36.443","article-title":"Expression of different glycoforms of membrane mucin (MUC1) and secretory mucin (MUC2 MUC5AC and MUC6) in pancreatic neoplasms","volume":"36","author":"Horinouchi","year":"2003","journal-title":"Acta Histochem. Cytochem."},{"key":"10.1016\/j.prp.2015.10.009_bib0160","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1097\/PAS.0b013e3181a162e5","article-title":"Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms","volume":"33","author":"Yamaguchi","year":"2009","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0165","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/path.4242","article-title":"The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant","volume":"231","author":"Yamaguchi","year":"2013","journal-title":"J. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0170","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/path.2875","article-title":"Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasms","volume":"224","author":"Xiao","year":"2011","journal-title":"J. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0175","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/path.4344","article-title":"Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas","volume":"233","author":"Amato","year":"2014","journal-title":"J. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0180","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1097\/PAS.0b013e31822769a0","article-title":"Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas","volume":"35","author":"Yamaguchi","year":"2011","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0185","series-title":"PCR Protocols","first-page":"153","article-title":"Sample preparation from paraffin embedded tissues","author":"Wright","year":"1990"},{"key":"10.1016\/j.prp.2015.10.009_bib0190","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1440-1827.2011.02734.x","article-title":"Mucins in human neoplasms: clinical pathology, gene expression and diagnostic application","volume":"61","author":"Yonezawa","year":"2011","journal-title":"Pathol. Int."},{"key":"10.1016\/j.prp.2015.10.009_bib0195","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/onc.2010.459","article-title":"GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin","volume":"30","author":"Inaguma","year":"2011","journal-title":"Oncogene"},{"key":"10.1016\/j.prp.2015.10.009_bib0200","first-page":"619","article-title":"Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer","volume":"38","author":"Hoshi","year":"2011","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.prp.2015.10.009_bib0205","doi-asserted-by":"crossref","first-page":"887","DOI":"10.3892\/ijo.2013.1760","article-title":"MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways","volume":"42","author":"Hoshi","year":"2013","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.prp.2015.10.009_bib0210","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00000658-199807000-00012","article-title":"K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas","volume":"228","author":"Bartsch","year":"1998","journal-title":"Ann. Surg."},{"key":"10.1016\/j.prp.2015.10.009_bib0215","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/00000658-199910000-00006","article-title":"Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy","volume":"230","author":"Jimenez","year":"1999","journal-title":"Ann. Surg."},{"key":"10.1016\/j.prp.2015.10.009_bib0220","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/01.MP.0000094088.37888.A6","article-title":"Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas","volume":"16","author":"Kim","year":"2003","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.prp.2015.10.009_bib0225","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1593\/neo.04445","article-title":"Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis","volume":"7","author":"L\u00f6hr","year":"2005","journal-title":"Neoplasia"},{"key":"10.1016\/j.prp.2015.10.009_bib0230","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/01.mpa.0000148513.69873.4b","article-title":"Intraductal tubular neoplasms of the pancreas: histogenesis and differentiation","volume":"30","author":"Tajiri","year":"2005","journal-title":"Pancreas"},{"key":"10.1016\/j.prp.2015.10.009_bib0235","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/00006676-200408000-00006","article-title":"Histologic and immunohistochemical comparison of intraductal tubular carcinoma, intraductal papillary-mucinous carcinoma, and ductal adenocarcinoma of the pancreas","volume":"29","author":"Tajiri","year":"2004","journal-title":"Pancreas"},{"key":"10.1016\/j.prp.2015.10.009_bib0240","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/MPA.0b013e318149f536","article-title":"Intraductal and cystic tubulopapillary adenocarcinoma of the pancreas: a possible variant of intraductal tubular carcinoma","volume":"36","author":"Konigsrainer","year":"2008","journal-title":"Pancreas"}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033815300285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033815300285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T04:37:56Z","timestamp":1567312676000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033815300285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":24,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0344033815300285"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2015.10.009","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2015.10.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}