{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:26:53Z","timestamp":1790872013161,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.prp.2017.05.005","type":"journal-article","created":{"date-parts":[[2017,5,20]],"date-time":"2017-05-20T00:01:59Z","timestamp":1495238519000},"page":"874-881","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics"],"prefix":"10.1016","volume":"213","author":[{"given":"V.","family":"Krenn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Perino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"R\u00fcther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.T.","family":"Krenn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"H\u00fcgle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Najm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Boettner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Pessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Waldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Kriegsmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Casadonte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"H\u00e4upl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wienert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.G.","family":"Krukemeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sesselmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sunitsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Tikhilov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Morawietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"February (1)","key":"10.1016\/j.prp.2017.05.005_bib0005","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13287-016-0460-7","article-title":"Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis","volume":"8","author":"Abdalmula","year":"2017","journal-title":"Cell Res. Ther."},{"issue":"2","key":"10.1016\/j.prp.2017.05.005_bib0010","doi-asserted-by":"crossref","first-page":"R57","DOI":"10.1186\/ar2678","article-title":"Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis","volume":"11","author":"Badot","year":"2009","journal-title":"Arthritis Res. Ther."},{"issue":"May (4)","key":"10.1016\/j.prp.2017.05.005_bib0015","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1302\/0301-620X.83B4.10425","article-title":"Recurring synovitis as a possible reason for aseptic loosening of knee endoprostheses in patients with rheumatoid arthritis","volume":"83","author":"Fink","year":"2001","journal-title":"J. Bone Joint Surg. Br."},{"issue":"October (5)","key":"10.1016\/j.prp.2017.05.005_bib0020","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1177\/1553350614549634","article-title":"Development of a new device for synovial biopsies","volume":"22","author":"H\u00fcgle","year":"2015","journal-title":"Surg Innov."},{"issue":"December (8)","key":"10.1016\/j.prp.2017.05.005_bib0025","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1007\/s00393-007-0232-y","article-title":"Synovitis score: value of histopathological diagnostics in unclear arthritis. Case reports from rheumatological pathological practice","volume":"66","author":"Jakobs","year":"2007","journal-title":"Z. Rheumatol."},{"issue":"September (7)","key":"10.1016\/j.prp.2017.05.005_bib0030","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s00393-015-1571-8","article-title":"CD15 focus score for diagnostics of periprosthetic joint infections: neutrophilic granulocytes quantification mode and the development of morphometric Software (CD15 quantifier)","volume":"74","author":"K\u00f6lbel","year":"2015","journal-title":"Z. Rheumatol."},{"issue":"5","key":"10.1016\/j.prp.2017.05.005_bib0035","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1078\/0344-0338-5710261","article-title":"Grading of chronic synovitis- a histopathological grading system for molecular and diagnostic pathology","volume":"198","author":"Krenn","year":"2002","journal-title":"Pathol. Res. Pract."},{"issue":"October (4)","key":"10.1016\/j.prp.2017.05.005_bib0040","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1365-2559.2006.02508.x","article-title":"Synovitis score: discrimination between chronic low-grade and high-grade synovitis","volume":"49","author":"Krenn","year":"2006","journal-title":"Histopathology"},{"issue":"November (6)","key":"10.1016\/j.prp.2017.05.005_bib0045","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s00292-006-0866-6","article-title":"Differential diagnosis of chronic synovitis","volume":"27","author":"Krenn","year":"2006","journal-title":"Pathologe"},{"issue":"March (3)","key":"10.1016\/j.prp.2017.05.005_bib0050","doi-asserted-by":"crossref","first-page":"893","DOI":"10.3892\/ijo.2014.2788","article-title":"MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics (review)","volume":"46","author":"Kriegsmann","year":"2015","journal-title":"Int. J. Oncol."},{"issue":"July (1)","key":"10.1016\/j.prp.2017.05.005_bib0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00428-016-1939-4","article-title":"Expression of miR-146a, miR-155, and miR-223 in formalin-fixed paraffin-embedded synovial tissues of patients with rheumatoid arthritis and osteoarthritis","volume":"469","author":"Kriegsmann","year":"2016","journal-title":"Virchows Arch."},{"issue":"April (4)","key":"10.1016\/j.prp.2017.05.005_bib0060","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1046\/j.1440-1827.1999.00863.x","article-title":"Synovitis in rheumatoid arthritis: scoring of characteristic histopathological features","volume":"49","author":"Koizumi","year":"1999","journal-title":"Pathol. Int."},{"issue":"December (12)","key":"10.1016\/j.prp.2017.05.005_bib0065","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.3899\/jrheum.151441","article-title":"Success rate and utility of ultrasound-guided synovial biopsies in clinical practice","volume":"43","author":"Najm","year":"2016","journal-title":"J. Rheumatol."},{"issue":"August (8)","key":"10.1016\/j.prp.2017.05.005_bib0070","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1136\/ard.2008.087775","article-title":"The synovitis of non-inflammatory orthopaedic arthropathies: a quantitative histological and immunohistochemical analysis","volume":"67","author":"Pessler","year":"2008","journal-title":"Ann. Rheum. Dis."},{"issue":"February (2)","key":"10.1016\/j.prp.2017.05.005_bib0075","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1136\/ard.2007.071670","article-title":"Subintimal Ki-67 as a synovial tissue biomarker for inflammatory arthropathies","volume":"67","author":"Pessler","year":"2008","journal-title":"Ann. Rheum. Dis."},{"issue":"July\u2013August(7\u20138)","key":"10.1016\/j.prp.2017.05.005_bib0080","first-page":"278","article-title":"The value of synovial biopsies in the diagnosis of rheumatoid arthritis and in estimating local inflammatory activity","volume":"35","author":"P\u00fcschel","year":"1976","journal-title":"Rheumatol"},{"issue":"February (7639)","key":"10.1016\/j.prp.2017.05.005_bib0085","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nature20810","article-title":"Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis","volume":"542","author":"Rao","year":"2017","journal-title":"Nature"},{"issue":"September (3)","key":"10.1016\/j.prp.2017.05.005_bib0090","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/j.1365-2559.2010.03641.x","article-title":"Quantitative determination of the diagnostic accuracy of the synovitis score and its components","volume":"57","author":"Slansky","year":"2010","journal-title":"Histopathology"},{"issue":"January (1)","key":"10.1016\/j.prp.2017.05.005_bib0095","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/annrheumdis-2015-207524","article-title":"Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force","volume":"75","author":"Smolen","year":"2016","journal-title":"Ann. Rheum. Dis."},{"issue":"May (3)","key":"10.1016\/j.prp.2017.05.005_bib0100","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00292-011-1419-1","article-title":"Osteoarthritis. Etiology, typing, staging and histological grading","volume":"32","author":"S\u00f6der","year":"2011","journal-title":"Pathologe"},{"issue":"March (3)","key":"10.1016\/j.prp.2017.05.005_bib0105","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S1357-2725(03)00259-0","article-title":"Rheumatoid arthritis: regulation of synovial inflammation","volume":"36","author":"Sweeney","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"November A(4)","key":"10.1016\/j.prp.2017.05.005_bib0110","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1152\/physiolgenomics.00004.2010","article-title":"Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis","volume":"42","author":"Ungethuem","year":"2010","journal-title":"Physiol. Genom."},{"issue":"January (1)","key":"10.1016\/j.prp.2017.05.005_bib0115","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/art.30100","article-title":"Classification of rheumatoid arthritis: comparison of the 1987 american college of rheumatology criteria and the 2010 american college of Rheumatology\/European league against rheumatism criteria","volume":"63","author":"van der Linden","year":"2011","journal-title":"Arthritis Rheum."},{"issue":"April (4)","key":"10.1016\/j.prp.2017.05.005_bib0120","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1093\/rheumatology\/kev330","article-title":"Immunopathology of synovitis: from histology to molecular pathways","volume":"55","author":"van de Sande","year":"2016","journal-title":"Rheumatology (Oxford)"},{"issue":"July (7)","key":"10.1016\/j.prp.2017.05.005_bib0125","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1007\/s11999-014-3583-0","article-title":"Does intraarticular inflammation predict biomechanical cartilage properties?","volume":"472","author":"Waldstein","year":"2014","journal-title":"Clin. Orthop. Relat. Res."},{"issue":"June (6)","key":"10.1016\/j.prp.2017.05.005_bib0130","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s00132-008-1399-x","article-title":"Osteoarthritis\u2013histopathologic diagnosis: typing, grading, and staging","volume":"38","author":"Zustin","year":"2009","journal-title":"Orthopade"}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033817303175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033817303175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T21:48:07Z","timestamp":1569361687000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033817303175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["S0344033817303175"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2017.05.005","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2017.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}