{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:50:39Z","timestamp":1790790639263,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.prp.2017.08.013","type":"journal-article","created":{"date-parts":[[2017,9,2]],"date-time":"2017-09-02T03:16:34Z","timestamp":1504322194000},"page":"1237-1241","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Current insight in the localized insulin-derived amyloidosis (LIDA): clinico-pathological characteristics and differential diagnosis"],"prefix":"10.1016","volume":"213","author":[{"given":"Amir Mehdi","family":"Ansari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lais","family":"Osmani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aerielle E.","family":"Matsangos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing K.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1 (January)","key":"10.1016\/j.prp.2017.08.013_bib0005","first-page":"108","article-title":"Iatrogenic, insulin-dependent, local amyloidosis","volume":"48","author":"Storkel","year":"1983","journal-title":"Lab. Invest."},{"issue":"2 (05\/16)","key":"10.1016\/j.prp.2017.08.013_bib0010","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3892\/etm.2014.1772","article-title":"Generating local amyloidosis in mice by the subcutaneous injection of human insulin amyloid fibrils","volume":"8","author":"Chinisaz","year":"2014","journal-title":"Exp. Ther. Med."},{"issue":"5 (May)","key":"10.1016\/j.prp.2017.08.013_bib0015","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.amjmed.2013.10.029","article-title":"Insulin-derived amyloidosis and poor glycemic control: a case series","volume":"127","author":"Nagase","year":"2014","journal-title":"Am. J. Med."},{"issue":"05\/09","key":"10.1016\/j.prp.2017.08.013_bib0020","first-page":"1","article-title":"Insulin amyloid at injection sites of patients with diabetes","author":"Nilsson","year":"2016","journal-title":"Amyloid"},{"issue":"10","key":"10.1016\/j.prp.2017.08.013_bib0025","doi-asserted-by":"crossref","first-page":"661","DOI":"10.2165\/00128071-200304100-00001","article-title":"Skin-related complications of insulin therapy: epidemiology and emerging management strategies","volume":"4","author":"Richardson","year":"2003","journal-title":"Am. J. Clin. Dermatol."},{"issue":"22 (June 11)","key":"10.1016\/j.prp.2017.08.013_bib0030","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1001\/jama.2014.5951","article-title":"Insulin therapy for type 2 diabetes mellitus","volume":"311","author":"Wallia","year":"2014","journal-title":"JAMA"},{"issue":"8 (August)","key":"10.1016\/j.prp.2017.08.013_bib0035","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.2337\/diacare.28.8.2025","article-title":"Impaired absorption of insulin aspart from lipohypertrophic injection sites","volume":"28","author":"Johansson","year":"2005","journal-title":"Diabetes Care"},{"issue":"4 (July\u2013August)","key":"10.1016\/j.prp.2017.08.013_bib0040","doi-asserted-by":"crossref","first-page":"773","DOI":"10.4103\/2230-8210.113788","article-title":"Insulin lipodystrophy and lipohypertrophy","volume":"17","author":"Mokta","year":"2013","journal-title":"Indian J. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.prp.2017.08.013_bib0045","doi-asserted-by":"crossref","first-page":"e2013005","DOI":"10.4084\/mjhid.2013.005","article-title":"Skin involvement in primary systemic amyloidosis","volume":"5","author":"Kumar","year":"2013","journal-title":"Mediterr. J. Hematol. Infect. Dis."},{"issue":"3 (March)","key":"10.1016\/j.prp.2017.08.013_bib0050","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-4362.2002.01411.x","article-title":"Cutaneous amyloidosis and possible association with systemic amyloidosis","volume":"41","author":"Steciuk","year":"2002","journal-title":"Int. J. Dermatol."},{"issue":"3","key":"10.1016\/j.prp.2017.08.013_bib0055","first-page":"138","article-title":"Human recombinant insulin and amyloidosis: an unexpected association","volume":"68","author":"Sie","year":"2010","journal-title":"Neth. J. Med."},{"issue":"3 (March)","key":"10.1016\/j.prp.2017.08.013_bib0060","doi-asserted-by":"crossref","first-page":"634","DOI":"10.2337\/diacare.25.3.634","article-title":"Lipohypertrophy in young patients with type 1 diabetes","volume":"25","author":"Kordonouri","year":"2002","journal-title":"Diabetes Care"},{"issue":"1 (January)","key":"10.1016\/j.prp.2017.08.013_bib0065","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2230.2012.04373.x","article-title":"Coexistence of insulin-derived amyloidosis and an overlying acanthosis nigricans-like lesion at the site of insulin injection","volume":"38","author":"Kudo-Watanuki","year":"2013","journal-title":"Clin. Exp. Dermatol."},{"issue":"6 (June)","key":"10.1016\/j.prp.2017.08.013_bib0070","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/dc.10296","article-title":"Amyloid tumor: a clinical and cytomorphologic study","volume":"28","author":"Sahoo","year":"2003","journal-title":"Diagn. Cytopathol."},{"issue":"6(December)","key":"10.1016\/j.prp.2017.08.013_bib0075","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1016\/j.jaad.2010.03.001","article-title":"Nodular amyloidosis in a diabetic patient with frequent hypoglycemia: sequelae of repeatedly injecting insulin without site rotation","volume":"63","author":"Endo","year":"2010","journal-title":"J. Am. Acad. Dermatol"},{"issue":"8 (December)","key":"10.1016\/j.prp.2017.08.013_bib0080","doi-asserted-by":"crossref","first-page":"e1027","DOI":"10.1111\/j.1365-2230.2009.03711.x","article-title":"Localized cutaneous amyloid at an insulin injection site","volume":"34","author":"Lonsdale-Eccles","year":"2009","journal-title":"Clin. Exp. Dermatol."},{"issue":"10 (October)","key":"10.1016\/j.prp.2017.08.013_bib0085","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1046\/j.1464-5491.2002.07581.x","article-title":"Examination of insulin injection sites: an unexpected finding of localized amyloidosis","volume":"19","author":"Swift","year":"2002","journal-title":"Diabet. Med."},{"issue":"3 (March)","key":"10.1016\/j.prp.2017.08.013_bib0090","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/BF00276849","article-title":"Insulin as an amyloid-fibril protein at sites of repeated insulin injections in a diabetic patient","volume":"31","author":"Dische","year":"1988","journal-title":"Diabetologia"},{"issue":"11 (November)","key":"10.1016\/j.prp.2017.08.013_bib0095","doi-asserted-by":"crossref","first-page":"E131","DOI":"10.1002\/ajh.23334","article-title":"Localized insulin-derived amyloidosis: a potential pitfall in the diagnosis of systemic amyloidosis by fat aspirate","volume":"87","author":"D'Souza","year":"2012","journal-title":"Am. J. Hematol."},{"issue":"12 (December)","key":"10.1016\/j.prp.2017.08.013_bib0100","doi-asserted-by":"crossref","first-page":"e200","DOI":"10.2337\/dc13-1651","article-title":"Localized amyloidosis at the site of repeated insulin injection in a patient with type 2 diabetes","volume":"36","author":"Okamura","year":"2013","journal-title":"Diabetes Care"},{"issue":"1 (January\u2013March)","key":"10.1016\/j.prp.2017.08.013_bib0105","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/0377-4929.130920","article-title":"Cutaneous amyloidosis and insulin with coexistence of acanthosis nigricans","volume":"57","author":"Nandeesh","year":"2014","journal-title":"Indian J. Pathol. Microbiol."},{"issue":"9658 (January)","key":"10.1016\/j.prp.2017.08.013_bib0110","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0140-6736(09)60041-6","article-title":"The insulin ball","volume":"373","author":"Nagase","year":"2009","journal-title":"Lancet"},{"issue":"3 (March)","key":"10.1016\/j.prp.2017.08.013_bib0115","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.diabres.2006.07.013","article-title":"Yadira Hurley M, Mooradian AD: Severe insulin resistance associated with subcutaneous amyloid deposition","volume":"75","author":"Albert","year":"2007","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"11 (November)","key":"10.1016\/j.prp.2017.08.013_bib0120","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.humpath.2009.02.019","article-title":"Localized insulin-derived amyloidosis in patients with diabetes mellitus: a case report","volume":"40","author":"Yumlu","year":"2009","journal-title":"Hum. Pathol."},{"issue":"5","key":"10.1016\/j.prp.2017.08.013_bib0125","doi-asserted-by":"crossref","first-page":"397","DOI":"10.2169\/internalmedicine.49.2633","article-title":"Localized amyloidosis at the site of repeated insulin injection in a diabetic patient","volume":"49","author":"Shikama","year":"2010","journal-title":"Intern. Med."},{"issue":"April 18","key":"10.1016\/j.prp.2017.08.013_bib0130","article-title":"Localized insulin amyloidosis with use of concentrated insulin: a potential complication","author":"Mangla","year":"2016","journal-title":"Diabet. Med."},{"issue":"1 (March 1)","key":"10.1016\/j.prp.2017.08.013_bib0135","first-page":"5","article-title":"Primary, systemic amyloidosis and the dermatologist: where classic skin lesions may provide the clue for early diagnosis","volume":"11","author":"Silverstein","year":"2005","journal-title":"Dermatol. Online J."},{"issue":"2 (March 9)","key":"10.1016\/j.prp.2017.08.013_bib0140","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.bbrc.2012.01.153","article-title":"Formation of low-dimensional crystalline nucleus region during insulin amyloidogenesis process","volume":"419","author":"Amdursky","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3 (February 17)","key":"10.1016\/j.prp.2017.08.013_bib0145","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.bbrc.2012.01.051","article-title":"Proinsulin C-peptide interferes with insulin fibril formation","volume":"418","author":"Landreh","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6 (November)","key":"10.1016\/j.prp.2017.08.013_bib0150","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00041552-200211000-00013","article-title":"Serum amyloid P component scintigraphy for diagnosis and monitoring amyloidosis","volume":"11","author":"Hawkins","year":"2002","journal-title":"Curr. Opin. Nephrol. Hypertens."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033817308750?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033817308750?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T05:23:59Z","timestamp":1535433839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033817308750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0344033817308750"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2017.08.013","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Current insight in the localized insulin-derived amyloidosis (LIDA): clinico-pathological characteristics and differential diagnosis","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2017.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}