{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:42:52Z","timestamp":1777869772331,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["1908085QH362"],"award-info":[{"award-number":["1908085QH362"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009558","name":"University Natural Science Research Project of Anhui Province","doi-asserted-by":"publisher","award":["KJ2019A0406"],"award-info":[{"award-number":["KJ2019A0406"]}],"id":[{"id":"10.13039\/501100009558","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.prp.2019.152790","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T19:38:08Z","timestamp":1576611488000},"page":"152790","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Adipocyte enhancer binding protein 1 (AEBP1) knockdown suppresses human glioma cell proliferation, invasion and induces early apoptosis"],"prefix":"10.1016","volume":"216","author":[{"given":"Limin","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuefei","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qifu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sansong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2019.152790_bib0005","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1038\/nrn1518","article-title":"DNA-microarray analysis of brain cancer: molecular classification for therapy","volume":"5","author":"Mischel","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.prp.2019.152790_bib0010","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.nec.2009.08.002","article-title":"Challenges in clinical design of Immunotherapy trials for malignant glioma","volume":"21","author":"Rolle","year":"2000","journal-title":"Neurosurg. Clin. N. Am."},{"key":"10.1016\/j.prp.2019.152790_bib0015","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1128\/MCB.01469-07","article-title":"Generation and activation of multiple dimeric transcription factors within the NF-kappaB signaling system","volume":"28","author":"Basak","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.prp.2019.152790_bib0020","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/nri.2017.142","article-title":"NF-kappaB, infammation, immunity and cancer: coming of age","volume":"18","author":"Taniguchi","year":"2018","journal-title":"Nat. Rev. Immunol."},{"issue":"378","key":"10.1016\/j.prp.2019.152790_bib0025","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/378092a0","article-title":"A eukaryotic transcriptional repressor with carboxypeptidase activity","author":"He","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.prp.2019.152790_bib0030","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000456061","article-title":"Potential regulators driving the transition in nonalcoholic fatty liver disease: a stage-based view","volume":"41","author":"Lou","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.prp.2019.152790_bib0035","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3389\/fphys.2017.00947","article-title":"Identifcation of biomarkers correlated with the TNM staging and overall survival of patients with bladder cancer","volume":"8","author":"Li","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.prp.2019.152790_bib0040","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1158\/1078-0432.CCR-13-1256","article-title":"A collagen-remodeling gene signature regulated by TGF-beta signaling is associated with metastasis and poor survival in serous ovarian cancer","volume":"20","author":"Cheon","year":"2014","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.prp.2019.152790_bib0045","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1158\/1541-7786.MCR-11-0488","article-title":"Identifcation of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells","volume":"10","author":"Ladha","year":"2012","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.prp.2019.152790_bib0050","doi-asserted-by":"crossref","first-page":"R56","DOI":"10.1186\/bcr1604","article-title":"Establishment of the epithelial-specifc transcriptome of normal and malignant human breast cells based on MPSS and array expression data","volume":"8","author":"Grigoriadis","year":"2006","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.prp.2019.152790_bib0055","doi-asserted-by":"crossref","first-page":"W98","DOI":"10.1093\/nar\/gkx247","article-title":"GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses","volume":"45","author":"Tang","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.prp.2019.152790_bib0060","doi-asserted-by":"crossref","first-page":"D956","DOI":"10.1093\/nar\/gkx1090","article-title":"Linked omics: analyzing multi-omics data within and across 32 cancer types","volume":"46","author":"Vasaikar","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.prp.2019.152790_bib0065","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1006\/bbrc.1996.1675","article-title":"A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line","volume":"2","author":"Ohno","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.prp.2019.152790_bib0070","doi-asserted-by":"crossref","first-page":"10199","DOI":"10.1074\/jbc.M010640200","article-title":"Regulation of adipogenesis by a transcriptional repressor that modulates MAPK activation","volume":"276","author":"Kim","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.prp.2019.152790_bib0075","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000456061","article-title":"Potential regulators driving the transition in nonalcoholic fatty liver disease: a stage-based view","volume":"1","author":"Lou","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.prp.2019.152790_bib0080","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/bpa.12475","article-title":"Association of adipocyte enhancer-binding protein 1 with Alzheimer\u2019s disease pathology in human hippocampi","volume":"28","author":"Shijo","year":"2018","journal-title":"Brain Pathol."},{"key":"10.1016\/j.prp.2019.152790_bib0085","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1158\/0008-5472.CAN-16-2114","article-title":"Loss of NDRG2 expression confers oral squamous cell carcinoma with enhanced metastatic potential","volume":"77","author":"Tamura","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2019.152790_bib0090","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.7150\/jca.20196","article-title":"Curcumin enhances the anticancer efect of 5-fuorouracil against gastric cancer through down-regulation of COX-2 and NF- kappaB signaling pathways","volume":"8","author":"Yang","year":"2017","journal-title":"J. Cancer"},{"key":"10.1016\/j.prp.2019.152790_bib0095","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1158\/0008-5472.CAN-17-1089","article-title":"The CARMA3-Bcl10-MALT1 signalosome drives NF-kappaB activation and promotes aggressiveness in angiotensin ii receptor-positive breast cancer","volume":"78","author":"Ekambaram","year":"2018","journal-title":"Cancer Res."},{"key":"10.1016\/j.prp.2019.152790_bib0100","article-title":"Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression","volume":"7","author":"Li","year":"2011","journal-title":"PLoS One"}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033819323775?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033819323775?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:38:20Z","timestamp":1777559900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033819323775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0344033819323775"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2019.152790","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adipocyte enhancer binding protein 1 (AEBP1) knockdown suppresses human glioma cell proliferation, invasion and induces early apoptosis","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2019.152790","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152790"}}