{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T04:12:41Z","timestamp":1774411961712,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"am","delay-in-days":344,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.prp.2022.153888","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T21:17:17Z","timestamp":1649193437000},"page":"153888","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Peripheral node addressin, a ligand for L-selectin is found in tumor cells and in high endothelial venules in endometrial cancer"],"prefix":"10.1016","volume":"233","author":[{"given":"Georgia","family":"Karpathiou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Sramek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami","family":"Dagher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mousa","family":"Mobarki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maroa","family":"Dridi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiphanie","family":"Picot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celine","family":"Chauleur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Peoc\u2019h","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2022.153888_bib1","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2015.1008791","article-title":"Understanding high endothelial venules: Lessons for cancer immunology","volume":"4","author":"Ager","year":"2015","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.prp.2022.153888_bib2","doi-asserted-by":"crossref","first-page":"99207","DOI":"10.18632\/oncotarget.22276","article-title":"Therapeutic induction of high endothelial venules (HEVs) to enhance T-cell infiltration in tumors","volume":"8","author":"Allen","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.prp.2022.153888_bib3","doi-asserted-by":"crossref","first-page":"829","DOI":"10.4161\/onci.20492","article-title":"High endothelial venules (HEVs) in human melanoma lesions","volume":"1","author":"Martinet","year":"2012","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.prp.2022.153888_bib4","doi-asserted-by":"crossref","first-page":"5678","DOI":"10.1158\/0008-5472.CAN-11-0431","article-title":"Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer","volume":"71","author":"Martinet","year":"2011","journal-title":"Cancer Res"},{"key":"10.1016\/j.prp.2022.153888_bib5","article-title":"High endothelial venules are present in pharyngeal and laryngeal carcinomas and they are associated with better prognosis","volume":"220","author":"Karpathiou","year":"2021","journal-title":"Pathol. - Res. Pr."},{"key":"10.1016\/j.prp.2022.153888_bib6","first-page":"1","article-title":"Correlation with lymphocyte infiltration, but lack of prognostic significance of MECA-79-positive high endothelial venules in primary malignant melanoma","author":"Sebesty\u00e9n","year":"2018","journal-title":"Melanoma Res"},{"key":"10.1016\/j.prp.2022.153888_bib7","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/s41416-019-0514-6","article-title":"High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer","volume":"121","author":"Pfuderer","year":"2019","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.prp.2022.153888_bib8","doi-asserted-by":"crossref","first-page":"399","DOI":"10.4143\/crt.2016.215","article-title":"Predictive value of tertiary lymphoid structures assessed by high endothelial venule counts in the neoadjuvant setting of triple-negative breast cancer","volume":"49","author":"Song","year":"2017","journal-title":"Cancer Res. Treat."},{"key":"10.1016\/j.prp.2022.153888_bib9","doi-asserted-by":"crossref","DOI":"10.4161\/2162402X.2014.974374","article-title":"High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression","volume":"4","author":"Bento","year":"2015","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.prp.2022.153888_bib10","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1007\/s13277-015-4036-4","article-title":"Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma","volume":"37","author":"Wirsing","year":"2016","journal-title":"Tumor Biol."},{"key":"10.1016\/j.prp.2022.153888_bib11","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/j.1349-7006.2011.01895.x","article-title":"Ectopic expression of MECA-79 as a novel prognostic indicator in gastric cancer","volume":"102","author":"Okayama","year":"2011","journal-title":"Cancer Sci."},{"key":"10.1016\/j.prp.2022.153888_bib12","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1038\/s41379-018-0019-5","article-title":"Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carcinoma","volume":"31","author":"Wirsing","year":"2018","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.prp.2022.153888_bib13","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1126\/science.1079546","article-title":"Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface","author":"Genbacev","year":"2003","journal-title":"Sci. (80-. ). 299"},{"key":"10.1016\/j.prp.2022.153888_bib14","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.fertnstert.2004.11.040","article-title":"Differential expression of L-selectin ligand in the endometrium during the menstrual cycle","volume":"83","author":"LAI","year":"2005","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.prp.2022.153888_bib15","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1093\/humrep\/dep247","article-title":"L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects","volume":"24","author":"Margarit","year":"2009","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.prp.2022.153888_bib16","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/s41598-018-19911-z","article-title":"Gene expression of human endometrial L-selectin ligand in relation to the phases of the natural menstrual cycle","volume":"8","author":"Lai","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.prp.2022.153888_bib17","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1093\/humrep\/deaa234","article-title":"Densities of decidual high endothelial venules correlate with T-cell influx in healthy pregnancies and idiopathic recurrent pregnancy losses","volume":"35","author":"Windsperger","year":"2020","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.prp.2022.153888_bib18","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/his.12235","article-title":"The density and type of MECA-79-positive high endothelial venules correlate with lymphocytic infiltration and tumour regression in primary cutaneous melanoma","volume":"63","author":"Avram","year":"2013","journal-title":"Histopathology"},{"key":"10.1016\/j.prp.2022.153888_bib19","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/s41379-018-0179-3","article-title":"Minimal microsatellite shift in microsatellite instability high endometrial cancer: a significant pitfall in diagnostic interpretation","volume":"32","author":"Wu","year":"2019","journal-title":"Mod. Pathol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033822001315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033822001315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T03:30:16Z","timestamp":1774409416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033822001315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":19,"alternative-id":["S0344033822001315"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2022.153888","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral node addressin, a ligand for L-selectin is found in tumor cells and in high endothelial venules in endometrial cancer","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2022.153888","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"153888"}}