{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:16:32Z","timestamp":1778541392723,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015763","name":"Szegedi Tudom\u00e1nyegyetem","doi-asserted-by":"publisher","award":["6855"],"award-info":[{"award-number":["6855"]}],"id":[{"id":"10.13039\/501100015763","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.prp.2024.155280","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T11:19:07Z","timestamp":1711970347000},"page":"155280","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The value of oestrogen receptor, progesterone receptor and keratins 5 and 14 immunohistochemistry in the evaluation of epithelial proliferations at cauterised margins in breast-conserving surgery specimens"],"prefix":"10.1016","volume":"257","author":[{"given":"Szintia","family":"Alm\u00e1si","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Cserni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2024.155280_bib1","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1056\/NEJMoa020989","article-title":"Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer","volume":"347","author":"Veronesi","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.prp.2024.155280_bib2","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1056\/NEJMoa022152","article-title":"Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer","volume":"347","author":"Fisher","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.prp.2024.155280_bib3","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1245\/s10434-022-12133-8","article-title":"Does Breast-Conserving Surgery with Radiotherapy have a Better Survival than Mastectomy? A Meta-Analysis of More than 1,500,000 Patients","volume":"29","author":"De la Cruz Ku","year":"2022","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.prp.2024.155280_bib4","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1245\/s10434-016-5313-1","article-title":"Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review","volume":"23","author":"De La Cruz","year":"2016","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.prp.2024.155280_bib5","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0360-3016(89)90057-6","article-title":"Prognostic factors of breast recurrence in the conservative management of early breast cancer: A 25-year follow-up","volume":"17","author":"Fourquet","year":"1989","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.prp.2024.155280_bib6","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1200\/JCO.1994.12.4.653","article-title":"Risk factors in breast-conservation therapy","volume":"12","author":"Borger","year":"1994","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.prp.2024.155280_bib7","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1002\/1097-0142(19940915)74:6<1746::AID-CNCR2820740617>3.0.CO;2-Y","article-title":"The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy","volume":"74","author":"Schnitt","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.prp.2024.155280_bib8","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1016\/j.ejca.2010.07.043","article-title":"Metaanalysis of the impact of surgical margins on local recurrence in women with early-stage invasive breast cancer treated with breast conserving surgery","volume":"46","author":"Houssami","year":"2010","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.prp.2024.155280_bib9","doi-asserted-by":"crossref","first-page":"575","DOI":"10.5858\/arpa.2014-0384-ED","article-title":"The Society of Surgical Oncology\u2013American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer. Perspectives for pathologists","volume":"139","author":"Schnitt","year":"2015","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.prp.2024.155280_bib10","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1002\/cncr.24874","article-title":"Locoregional treatment of primary breast cancer: consensus recommendations from an International Expert Panel","volume":"116","author":"Kaufmann","year":"2010","journal-title":"Cancer"},{"key":"10.1016\/j.prp.2024.155280_bib11","unstructured":"American Society of Breast Surgeons, Official statement: Consensus Guideline on Breast Cancer Lumpectomy Margins. \u3008https:\/\/www.breastsurgeons.org\/docs\/statements\/Consensus-Guideline-on-Breast-Cancer-Lumpectomy-Margins.pdf\u3009 (Accessed 15 Dec 2025)."},{"key":"10.1016\/j.prp.2024.155280_bib12","unstructured":"Association of Breast Surgery Consensus Statement: Margin width in breast conservation surgery. \u3008https:\/\/associationofbreastsurgery.org.uk\/media\/64245\/final-margins-consensus-statement.pdf#:\u223c:text=Voting%20breakdown%20showed%20that%2088%25%20of%20the%20consultant,breast.%E2%80%9D%2069%25%20voted%20in%20favour%2031%25%20voted%20against\u3009 (Accessed 04 Dec 2023)."},{"key":"10.1016\/j.prp.2024.155280_bib13","first-page":"457","article-title":"A comparison between scalpel and electrocautery in modified radical mastectomy","volume":"159","author":"Sheen-Chen","year":"1993","journal-title":"Eur. J. Surg."},{"key":"10.1016\/j.prp.2024.155280_bib14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0748-7983(95)90171-X","article-title":"A comparison of two surgical techniques for performing mastectomy","volume":"21","author":"Kurtz","year":"1995","journal-title":"Eur. J. Surg. Oncol."},{"key":"10.1016\/j.prp.2024.155280_bib15","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/path.982","article-title":"Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns","volume":"195","author":"Boecker","year":"2001","journal-title":"J. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib16","article-title":"Pathology reporting of breast disease in surgical excision specimens incorporating the dataset for histological reporting of breast cancer","author":"Ellis","year":"2016","journal-title":"R. Coll. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib17","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/path.1241","article-title":"Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ","volume":"198","author":"Boecker","year":"2002","journal-title":"J. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib18","first-page":"946","article-title":"The Consensus Conference on the Treatment of in situ Ductal Carcinoma of the Breast","volume":"88","author":"Schwarz","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.prp.2024.155280_bib19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10147-007-0673-y","article-title":"Role of 10-Gy boost radiation after breast-conserving surgery for stage I-II breast cancer with a 5-mm negative margin","volume":"12","author":"Notani","year":"2007","journal-title":"Int. J. Clin. Oncol."},{"key":"10.1016\/j.prp.2024.155280_bib20","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/ajcp\/110.5.641","article-title":"Sensitivity and specificity of antibodies on necrotic tumor tissue","volume":"110","author":"Judkins","year":"1998","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib21","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0046-8177(99)90071-0","article-title":"Utility of immunohistochemistry in the evaluation of necrotic thyroid tumors","volume":"30","author":"Judkins","year":"1999","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib22","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1309\/WKEN4ER9GXJ9GG31","article-title":"Immunohistochemical evaluation of necrotic malignant melanomas","volume":"127","author":"Nonaka","year":"2007","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib23","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/PAI.0000000000000599","article-title":"34BetaE12 and Alfa-Methylacyl Coenzyme A Racemase (AMACR) Antibodies Better Than p63 Antibody Distinguish Normal and Neoplastic Glands in Prostatic Tissue With Thermal Artifacts","volume":"27","author":"Pierconti","year":"2019","journal-title":"Appl. Immunohistochem. Mol. Morphol."},{"key":"10.1016\/j.prp.2024.155280_bib24","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.5858\/2007-131-1089-UOMKIE","article-title":"Utility of MIB-1 (Ki-67) in evaluating diminutive colorectal polyps with cautery artifact","volume":"131","author":"Groisman","year":"2007","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.prp.2024.155280_bib25","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/PAS.0b013e3181da7650","article-title":"Diagnostic use of antibody to smoothelin in the recognition of muscularis propria in transurethral resection of urinary bladder tumor (TURBT) specimens","volume":"34","author":"Paner","year":"2010","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib26","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.anndiagpath.2010.12.005","article-title":"Utility of cytokeratin 5\/6 and high-molecular-weight keratin in evaluation of cauterized surgical margins in excised specimens of breast ductal carcinoma in situ","volume":"15","author":"Nayak","year":"2011","journal-title":"Ann. Diagn. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib27","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/PAS.0000000000000853","article-title":"Solid Papillary Breast Carcinomas Resembling the Tall Cell Variant of Papillary Thyroid Neoplasms: A Unique Invasive Tumor With Indolent Behavior","volume":"41","author":"Foschini","year":"2017","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib28","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1053\/hupa.2002.124789","article-title":"Combined E-cadherin and high molecular weight cytokeratin immunoprofile differentiates lobular, ductal, and hybrid mammary intraepithelial neoplasias","volume":"33","author":"Bratthauer","year":"2002","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib29","doi-asserted-by":"crossref","first-page":"5367","DOI":"10.1158\/1078-0432.CCR-04-0220","article-title":"Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma","volume":"10","author":"Nielsen","year":"2004","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.prp.2024.155280_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000279","article-title":"Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies","volume":"7","author":"Blows","year":"2010","journal-title":"PloS. Med."},{"key":"10.1016\/j.prp.2024.155280_bib31","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00428-021-03185-4","article-title":"Apocrine lesions of the breast","volume":"480","author":"Quinn","year":"2022","journal-title":"Virchows Arch."},{"key":"10.1016\/j.prp.2024.155280_bib32","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1136\/jcp-2022-208389","article-title":"Papillomatous breast lesions with atypical columnar cell features","volume":"76","author":"de Boer","year":"2023","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.prp.2024.155280_bib33","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1309\/AJCPF4O0ADKFMGRJ","article-title":"The diagnostic utility of the minimal carcinoma triple stain in breast carcinomas","volume":"139","author":"Ross","year":"2013","journal-title":"Am. J. Clin. Pathol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033824001912?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033824001912?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T22:41:42Z","timestamp":1778539302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033824001912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":33,"alternative-id":["S0344033824001912"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2024.155280","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The value of oestrogen receptor, progesterone receptor and keratins 5 and 14 immunohistochemistry in the evaluation of epithelial proliferations at cauterised margins in breast-conserving surgery specimens","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2024.155280","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"155280"}}