{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:11:45Z","timestamp":1784128305421,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073397"],"award-info":[{"award-number":["82073397"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82202835"],"award-info":[{"award-number":["82202835"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002402","name":"Sun Yat-Sen University","doi-asserted-by":"publisher","award":["2020GZRPYMS01"],"award-info":[{"award-number":["2020GZRPYMS01"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002402","name":"Sun Yat-Sen University","doi-asserted-by":"publisher","award":["2023WW604"],"award-info":[{"award-number":["2023WW604"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["202201020455"],"award-info":[{"award-number":["202201020455"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["202201020407"],"award-info":[{"award-number":["202201020407"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002912","name":"Government of Guangdong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515012555"],"award-info":[{"award-number":["2022A1515012555"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012426"],"award-info":[{"award-number":["2024A1515012426"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.prp.2025.155848","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T04:19:53Z","timestamp":1740457193000},"page":"155848","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Clinicopathological analysis of lymphoepithelioma-like intrahepatic cholangiocarcinoma"],"prefix":"10.1016","volume":"268","author":[{"given":"Haifeng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidong","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sihong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunkui","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianning","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.prp.2025.155848_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s13000-020-01035-6","article-title":"Lymphoepithelioma-like carcinoma in liver not associated with Epstein-Barr virus: a report of 3 cases and literature review","volume":"15","author":"Zhang","year":"2020","journal-title":"Diagn. Pathol."},{"issue":"1","key":"10.1016\/j.prp.2025.155848_bib2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.4103\/IJPM.IJPM_761_17","article-title":"Lymphoepithelioma-like carcinoma of breast: a case report and review of the literature","volume":"62","author":"Nieto-Coronel","year":"2019","journal-title":"Indian J. Pathol. Microbiol"},{"issue":"8","key":"10.1016\/j.prp.2025.155848_bib3","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.5858\/arpa.2018-0149-RS","article-title":"Pulmonary Lymphoepithelioma-like carcinoma","volume":"143","author":"Sathirareuangchai","year":"2019","journal-title":"Arch. Pathol. Lab Med"},{"key":"10.1016\/j.prp.2025.155848_bib4","first-page":"1876218","article-title":"Primary lymphoepithelioma-like carcinoma of the prostate gland: a review of the literature","volume":"2016","author":"Venyo","year":"2016","journal-title":"Sci. (Cairo)"},{"issue":"4","key":"10.1016\/j.prp.2025.155848_bib5","doi-asserted-by":"crossref","first-page":"516","DOI":"10.4103\/0974-7796.164853","article-title":"Lymphoepithelioma-like carcinoma of the urinary bladder: a rare case report","volume":"7","author":"Raphael","year":"2015","journal-title":"Urol. Ann."},{"issue":"2","key":"10.1016\/j.prp.2025.155848_bib6","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s13193-015-0405-0","article-title":"Lymphoepithelioma-like carcinoma of endometrium; a rare case report","volume":"6","author":"Makannavar","year":"2015","journal-title":"Indian J. Surg. Oncol."},{"issue":"2","key":"10.1016\/j.prp.2025.155848_bib7","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s10120-014-0376-9","article-title":"Is gastric lymphoepithelioma-like carcinoma a special subtype of EBV-associated gastric carcinoma? New insight based on clinicopathological features and EBV genome polymorphisms","volume":"18","author":"Cheng","year":"2015","journal-title":"Gastric Cancer"},{"issue":"3","key":"10.1016\/j.prp.2025.155848_bib8","first-page":"3282","article-title":"Primary lymphoepithelioma-like hepatocellular carcinoma: report of a locally advanced case and review of literature","volume":"8","author":"An","year":"2015","journal-title":"Int J. Clin. Exp. Pathol."},{"issue":"12","key":"10.1016\/j.prp.2025.155848_bib9","first-page":"996","article-title":"Lymphoepithelioma-Iike hepatic carcinoma: the current status and progress","volume":"42","author":"Tao","year":"2020","journal-title":"Zhonghua Zhong Liu Za Zhi"},{"issue":"4","key":"10.1016\/j.prp.2025.155848_bib10","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.jhep.2020.10.037","article-title":"Clinicopathologic features, tumor immune microenvironment and genomic landscape of Epstein-Barr virus-associated intrahepatic Cholangiocarcinoma","volume":"74","author":"Huang","year":"2021","journal-title":"J. Hepatol."},{"issue":"4","key":"10.1016\/j.prp.2025.155848_bib11","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/jmv.21731","article-title":"Association of distinctive epstein-barr virus variants with gastric carcinoma in Guangzhou, Southern China.","volume":"82","author":"Chen","year":"2010","journal-title":"J. Med Virol."},{"issue":"7","key":"10.1016\/j.prp.2025.155848_bib12","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2019-229520","article-title":"An EBV+\u2009lymphoepithelioma-like cholangiocarcinoma in a young woman with chronic hepatitis B","volume":"12","author":"Gearty","year":"2019","journal-title":"BMJ Case Rep."},{"issue":"1","key":"10.1016\/j.prp.2025.155848_bib13","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1159\/000324485","article-title":"Intrahepatic lymphoepithelioma-like cholangiocarcinoma not associated with Epstein-Barr virus: a case report","volume":"4","author":"Lee","year":"2011","journal-title":"Case Rep. Oncol."},{"issue":"7","key":"10.1016\/j.prp.2025.155848_bib14","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.ajpath.2017.02.022","article-title":"Lymphoepithelioma-like carcinoma in liver","volume":"187","author":"Labgaa","year":"2017","journal-title":"Am. J. Pathol."},{"issue":"8","key":"10.1016\/j.prp.2025.155848_bib15","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0046-8177(96)90460-8","article-title":"Clonal Epstein-Barr virus associated cholangiocarcinoma with lymphoepithelioma-like component","volume":"27","author":"Hsu","year":"1996","journal-title":"Hum. Pathol."},{"issue":"14","key":"10.1016\/j.prp.2025.155848_bib16","article-title":"Lymphoepithelioma-like cholangiocarcinoma not associated with Epstein-Barr virus or hepatitis virus: case report and literature review of 100 reported cases","volume":"24","author":"Adachi","year":"2022","journal-title":"Ther. Adv. Med Oncol."},{"issue":"5","key":"10.1016\/j.prp.2025.155848_bib17","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1007\/s12072-022-10346-3","article-title":"The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma","volume":"16","author":"Chiang","year":"2022","journal-title":"Hepatol. Int"},{"issue":"2","key":"10.1016\/j.prp.2025.155848_bib18","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s12328-020-01303-4","article-title":"Lymphoepithelioma-like cholangiocarcinoma with Epstein-Barr virus infection treated by radiofrequency ablation","volume":"14","author":"Nogami","year":"2021","journal-title":"Clin. J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.prp.2025.155848_bib19","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2214\/AJR.20.22937","article-title":"The CT and MRi features of primary intrahepatic lymphoepithelioma-like cholangiocarcinoma","volume":"216","author":"Yang","year":"2021","journal-title":"AJR Am. J. Roentgenol."},{"issue":"13","key":"10.1016\/j.prp.2025.155848_bib20","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.3748\/wjg.v21.i13.4089","article-title":"Lymphoepithelioma-like cholangiocarcinoma: A mimic of hepatocellular carcinoma on imaging features","volume":"21","author":"Liao","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"5","key":"10.1016\/j.prp.2025.155848_bib21","first-page":"2421","article-title":"Clinicopathologic characteristics of inflammatory pseudotumor-like follicular dendritic cell sarcoma","volume":"7","author":"Ge","year":"2014","journal-title":"Int J. Clin. Exp. Pathol."},{"issue":"39","key":"10.1016\/j.prp.2025.155848_bib22","article-title":"Hepatic inflammatory pseudotumor-like follicular dendritic cell tumor with hepatic lymphoma history: A case report and literature review","volume":"100","author":"Li","year":"2021","journal-title":"Med. (Baltim.)"},{"key":"10.1016\/j.prp.2025.155848_bib23","series-title":"WHO classification of tumours of Haematopoietic and Lymphoid tissues","first-page":"424","author":"Swerdlow","year":"2017"},{"issue":"3","key":"10.1016\/j.prp.2025.155848_bib24","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/PAS.0000000000000376","article-title":"Lymphoepithelioma-like hepatocellular carcinoma: an uncommon variant of hepatocellular carcinoma with favorable outcome","volume":"39","author":"Chan","year":"2015","journal-title":"Am. J. Surg. Pathol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033825000408?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033825000408?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T08:25:39Z","timestamp":1778747139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033825000408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":24,"alternative-id":["S0344033825000408"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2025.155848","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinicopathological analysis of lymphoepithelioma-like intrahepatic cholangiocarcinoma","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2025.155848","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"155848"}}