{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:39:52Z","timestamp":1755225592369,"version":"3.43.0"},"reference-count":105,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.prp.2025.156153","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T06:50:03Z","timestamp":1753944603000},"page":"156153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Methyl jasmonate mitigates cisplatin-induced nephrotoxicity via modulation of Caspase-3\/COX-2\/ NF-\u03baB signalling pathway: In silico, In vitro, and In vivo investigations"],"prefix":"10.1016","volume":"273","author":[{"given":"Ujwal N.","family":"Katolkar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay J.","family":"Surana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.prp.2025.156153_bib1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.kisu.2021.11.003","article-title":"Epidemiology of chronic kidney disease: an update 2022","volume":"12","author":"Kovesdy","year":"2022","journal-title":"Kidney Int. Suppl."},{"key":"10.1016\/j.prp.2025.156153_bib2","doi-asserted-by":"crossref","first-page":"1526482","DOI":"10.3389\/fendo.2025.1526482","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2021: a systematic analysis for the global burden of disease study 2021","volume":"16","author":"Xie","year":"2025","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.prp.2025.156153_bib3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/B978-0-443-30080-6.00010-9","article-title":"Chronic kidney disease: causes, treatment, management, and future scope","author":"Ahmed","year":"2025","journal-title":"Comput. Intell. Genomics Data"},{"key":"10.1016\/j.prp.2025.156153_bib4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41572-024-00589-9","article-title":"Chronic kidney disease","volume":"11","author":"Romagnani","year":"2025","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.prp.2025.156153_bib5","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/apt.18426","article-title":"Mortality of acute kidney injury in cirrhosis: a systematic review and meta-analysis of over 5 million patients across different clinical settings","volume":"61","author":"Lekakis","year":"2025","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.prp.2025.156153_bib6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.2147\/AMEP.S516379","article-title":"Impact of an educational intervention on Nurses\u2019 knowledge and practice in early detection of acute kidney injury at mbarara regional referral hospital, Western Uganda","author":"Phiona","year":"2025","journal-title":"Adv. Med. Educ. Pr."},{"key":"10.1016\/j.prp.2025.156153_bib7","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1021\/acssensors.1c00422","article-title":"A novel fluorogenic assay for the detection of Nephrotoxin-Induced oxidative stress in live cells and renal tissue","volume":"6","author":"Mukherjee","year":"2021","journal-title":"ACS Sens."},{"key":"10.1016\/j.prp.2025.156153_bib8","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.3390\/jcm14051409","article-title":"Evaluation of aciclovir-induced nephrotoxicity in critically ill patients: a propensity-matched cohort study","volume":"14","author":"Boosman","year":"2025","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.prp.2025.156153_bib9","first-page":"371","article-title":"The acute kidney intervention and pharmacotherapy (AKIP) list: standardized list of medications that are renally eliminated and nephrotoxic in the acutely ill","volume":"59","author":"Barreto","year":"2025","journal-title":"Ann. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.4062\/biomolther.2012.20.3.268","article-title":"Drug-induced nephrotoxicity and its biomarkers","volume":"20","author":"Kim","year":"2012","journal-title":"Biomol. Ther. (Seoul. )."},{"key":"10.1016\/j.prp.2025.156153_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.drudis.2023.103819","article-title":"Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment","volume":"29","author":"Khan","year":"2024","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.prp.2025.156153_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2024.109724","article-title":"Peptide-based strategies for overcoming multidrug-resistance in cancer therapy","volume":"36","author":"Luo","year":"2025","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.prp.2025.156153_bib13","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jconrel.2025.01.008","article-title":"Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation","volume":"379","author":"Zhang","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.prp.2025.156153_bib14","first-page":"1","article-title":"Pharmacological, computational, and mechanistic insights into triptolide\u2019s role in targeting drug-resistant cancers","author":"Hussain","year":"2025","journal-title":"Naunyn. Schmiede Arch. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s40360-025-00890-7","article-title":"A disproportionality analysis of adverse events associated with loop diuretics in the FDA adverse event reporting system (FAERS)","volume":"26","author":"Xue","year":"2025","journal-title":"BMC Pharmacol. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib16","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3390\/metabo15030191","article-title":"Kidney toxicity of drugs for the heart: an updated perspective","volume":"15","author":"Caiati","year":"2025","journal-title":"Metabolites"},{"key":"10.1016\/j.prp.2025.156153_bib17","doi-asserted-by":"crossref","DOI":"10.1515\/jbcpp-2024-0220","article-title":"Navigating nephropathy and nephrotoxicity: understanding pathophysiology unveiling clinical manifestations, and exploring treatment approaches","author":"Javed","year":"2025","journal-title":"J. Basic Clin. Physiol. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib18","first-page":"959","article-title":"Nephrotoxic medication exposure in US adults with predialysis chronic kidney disease: health services utilization and cost outcomes","volume":"22","author":"Davis-Ajami","year":"2016","journal-title":"J. Manag. Care Spec. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jcis.2024.10.198","article-title":"Fullerenols as efficient ferroptosis inhibitor by targeting lipid peroxidation for preventing drug-induced acute kidney injury","volume":"680","author":"Chen","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.prp.2025.156153_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2024.112598","article-title":"Non-small nanoprobes based on FDA-approval formulation for NIR-II imaging and detection of drug-induced acute kidney injury","volume":"235","author":"Zhang","year":"2025","journal-title":"Dye. Pigment"},{"key":"10.1016\/j.prp.2025.156153_bib21","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1080\/17425255.2018.1473376","article-title":"Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication","volume":"14","author":"Momper","year":"2018","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib22","first-page":"1","article-title":"A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury","volume":"11","author":"Kim","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.prp.2025.156153_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00438-024-02219-1","article-title":"Methyltransferase-like 14 promotes ferroptosis in sepsis-induced acute kidney injury via increasing the m6A methylation modification of LPCAT3","volume":"300","author":"Xu","year":"2025","journal-title":"Mol. Genet. Genom."},{"key":"10.1016\/j.prp.2025.156153_bib24","first-page":"1","article-title":"Polystyrene nanoplastics exacerbate gentamicin-induced nephrotoxicity in adult rat by activating oxidative stress, inflammation and apoptosis pathways","author":"Boukholda","year":"2025","journal-title":"Naunyn. Schmiede Arch. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.kint.2024.09.017","article-title":"Diagnosis and management of immune checkpoint inhibitor\u2013associated nephrotoxicity: a position statement from the American society of Onco-nephrology","volume":"107","author":"Herrmann","year":"2025","journal-title":"Kidney Int"},{"key":"10.1016\/j.prp.2025.156153_bib26","doi-asserted-by":"crossref","DOI":"10.1172\/JCI188358","article-title":"Adding insult to injury: the spectrum of tubulointerstitial responses in acute kidney injury","volume":"135","author":"Baker","year":"2025","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.prp.2025.156153_bib27","article-title":"Diagnostic approach to glomerular diseases","volume":"8","author":"Babarinde","year":"2025","journal-title":"IJS Glob. Heal"},{"key":"10.1016\/j.prp.2025.156153_bib28","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s12882-025-04030-5","article-title":"Acute tubulointerstitial nephritis (ATIN) including drug-induced, tubulointerstitial nephritis and uveitis (TINU), ANCA-associated vasculitis (AAV), kidney-limited sarcoidosis, and hemolysis: a case series from Syria","volume":"26","author":"Alsultan","year":"2025","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.prp.2025.156153_bib29","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.cbi.2015.06.036","article-title":"Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-\u03baB and P53 signaling pathways","volume":"239","author":"Chtourou","year":"2015","journal-title":"Chem. Biol. Inter."},{"key":"10.1016\/j.prp.2025.156153_bib30","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.kint.2016.10.011","article-title":"Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury","volume":"91","author":"Oh","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.prp.2025.156153_bib31","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s12013-014-0231-y","article-title":"Nephroprotective effect of gelsemine against cisplatin-induced toxicity is mediated via attenuation of oxidative stress","volume":"71","author":"Lin","year":"2015","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.prp.2025.156153_bib32","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2174\/1570159X23666241206102022","article-title":"Co-administration of naringin and NLRP3 inhibitor improves myelin repair and mitigates oxidative stress in Cuprizone-Induced demyelination model","volume":"23","author":"Kalaki-Jouybari","year":"2025","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.prp.2025.156153_bib33","first-page":"ioaf032","article-title":"Reactive oxygen and nitrogen species: multifaceted regulators of ovarian activity","author":"Bezd\u00ed\u010dek","year":"2025","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.prp.2025.156153_bib34","first-page":"1","article-title":"Generation of cellular reactive oxygen and nitrogen species by exposure to ultraviolet radiation","author":"Menoni","year":"2025","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.prp.2025.156153_bib35","series-title":"Curr. Protein Pept. Sci.","article-title":"The role of sirtuins in diabetic nephropathy: a comprehensive review","author":"Wal","year":"2025"},{"key":"10.1016\/j.prp.2025.156153_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2024.112800","article-title":"Carbon nanotube-mediated platinum-based drug delivery for the treatment of cancer: advancements and future perspectives","volume":"206","author":"Sameer Khan","year":"2024","journal-title":"Eur. Polym. J."},{"key":"10.1016\/j.prp.2025.156153_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2025.115334","article-title":"Theaflavin alleviates cisplatin-induced nephrotoxicity: targeting SIRT1\/p53\/FOXO3a\/Nrf2 signaling and the NF-kB inflammatory cascade","volume":"198","author":"Alanazi","year":"2025","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s00344-024-11412-w","article-title":"Molecular crosstalk of jasmonate with major phytohormones and plant growth regulators during diverse stress responses","volume":"44","author":"Samanta","year":"2025","journal-title":"J. Plant Growth Regul."},{"key":"10.1016\/j.prp.2025.156153_bib39","first-page":"1","article-title":"Methyl jasmonate: bridging plant defense mechanisms and human therapeutics","author":"Sharma","year":"2025","journal-title":"Naunyn. Schmiede Arch. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1180618","article-title":"Inhibitory effects of jasminum grandiflorum L. essential oil on lipopolysaccharide-induced microglia activation-integrated characteristic analysis of volatile compounds, network pharmacology, and BV-2 cell","volume":"14","author":"Lu","year":"2023","journal-title":"Front. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib41","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.3390\/ijms26073016","article-title":"Metabolic and mitochondrial dysregulations in diabetic cardiac complications","volume":"26","author":"Tashkandi","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2025.156153_bib42","doi-asserted-by":"crossref","first-page":"339","DOI":"10.3390\/antiox14030339","article-title":"The interplay between autophagy and apoptosis in the mechanisms of action of stilbenes in cancer cells","volume":"14","author":"Siedlecka-Kroplewska","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.prp.2025.156153_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/07388551.2024.2438161","article-title":"Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects","author":"Sarsaiya","year":"2025","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/j.prp.2025.156153_bib44","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3390\/plants14071034","article-title":"Unlocking the therapeutic potential of patchouli leaves: a comprehensive review of phytochemical and pharmacological insights","volume":"14","author":"Mrisho","year":"2025","journal-title":"Plants"},{"key":"10.1016\/j.prp.2025.156153_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/antiox8100485","article-title":"Methyl jasmonate reduces inflammation and oxidative stress in the brain of arthritic rats","volume":"8","author":"Pereira-Mar\u00f3stica","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.prp.2025.156153_bib46","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19159719","article-title":"Rosinidin protects against cisplatin-induced nephrotoxicity via subsiding proinflammatory and oxidative stress biomarkers in rats","volume":"19","author":"Gilani","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.prp.2025.156153_bib47","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1177\/1091581810387164","article-title":"Comparative nephrotoxicity of aristolochic acid and tetrandrine in vitro and in vivo","volume":"30","author":"Yuan","year":"2011","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib48","first-page":"1","article-title":"3-(3-(diethylamino) propyl)-2-(4-(methylthio) phenyl) thiazolidin-4-one attenuates scopolamine-induced cognitive impairment in rats: insights into neuroprotective effects","author":"de Souza","year":"2025","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.prp.2025.156153_bib49","doi-asserted-by":"crossref","first-page":"11278","DOI":"10.1039\/D3RA01145C","article-title":"Molecular docking, molecular dynamics simulations and in vitro screening reveal cefixime and ceftriaxone as GSK3\u03b2 covalent inhibitors","volume":"13","author":"Nassar","year":"2023","journal-title":"RSC Adv."},{"key":"10.1016\/j.prp.2025.156153_bib50","doi-asserted-by":"crossref","first-page":"356","DOI":"10.6026\/97320630017356","article-title":"Molecular docking analysis of furfural and isoginkgetin with heme oxygenase I and PPAR\u03b3","volume":"17","author":"Santhakumar","year":"2021","journal-title":"Bioinformation"},{"key":"10.1016\/j.prp.2025.156153_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2019.110758","article-title":"Discovery of Keap1\u2212 Nrf2 small\u2212 molecule inhibitors from phytochemicals based on molecular docking","volume":"133","author":"Li","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.150925","article-title":"Ethyl gallate ameliorates diabetes-induced Alzheimer\u2019s disease-like phenotype in rats via activation of \u03b17 nicotinic receptors and mitigation of oxidative stress","volume":"737","author":"Nagori","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.prp.2025.156153_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e22480","article-title":"Systematic analysis of antimicrobial activity, phytochemistry, and in silico molecular interaction of selected essential oils and their formulations from different Indian spices against foodborne bacteria","volume":"9","author":"Gupta","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.prp.2025.156153_bib54","article-title":"Molecular docking approach to identify xanthine oxidase inhibitory effect of bioactive compounds in pogostemon cablin (Blanco) benth","volume":"27","author":"THANH","year":"2023","journal-title":"J. Res. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174645","article-title":"Ameliorative potential of phloridzin in type 2 diabetes-induced memory deficits in rats","volume":"913","author":"Kamdi","year":"2021","journal-title":"Eur. J. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib56","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.biopha.2018.02.052","article-title":"Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer\u2019s disease via activation of Nrf2\/ARE pathway and inhibition of \u03b2-secretase","volume":"101","author":"Nakhate","year":"2018","journal-title":"Biomed. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115364","article-title":"Effects of mitragynine on viability, proliferation, and migration of C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 immortalized mouse hippocampal neuron cell lines","volume":"166","author":"Viwatpinyo","year":"2023","journal-title":"Biomed. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib58","article-title":"Potential of asiaticoside encapsulated alginate chitosan nanoparticles in the management of antiproliferative activity in C6 glioma cells","volume":"5","author":"Kunjumon","year":"2024","journal-title":"Brain Behav. Immun. Integr."},{"key":"10.1016\/j.prp.2025.156153_bib59","series-title":"Pharmacogn. Mag.","article-title":"Morin inhibits cell proliferation and induces Caspase-mediated apoptotic cell death in glioma C6 cell line","author":"Zhu","year":"2024"},{"key":"10.1016\/j.prp.2025.156153_bib60","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.prp.2025.156153_bib61","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0022-1759(89)90397-9","article-title":"Re-examination and further development of a precise and rapid dye method for measuring cell growth\/cell kill","volume":"119","author":"Hansen","year":"1989","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.prp.2025.156153_bib62","first-page":"56","article-title":"Apoptosis induction in ascorbic acid treated human colorectal cancer cell lines (Caco-2)","volume":"15","author":"Mustafa","year":"2025","journal-title":"J. Biol. Act. Prod. Nat."},{"key":"10.1016\/j.prp.2025.156153_bib63","first-page":"1","article-title":"\u03b2-Caryophyllene (CB2 agonist) mitigates rotenone-induced neurotoxicity and apoptosis in SH-SY5Y neuroblastoma cells via modulation of GSK-3\u03b2\/NRF2\/HO-1 axis","author":"Rathod","year":"2025","journal-title":"Naunyn. Schmiedebergs. Arch. Pharmacol."},{"key":"10.1016\/j.prp.2025.156153_bib64","doi-asserted-by":"crossref","DOI":"10.2174\/0113892037334392241216074545","article-title":"In-vitro, In-silico InvestigationsRevealsPotential cytotoxic activity of fermentation metabolites from actinomycetes isolated from lonar soda lake against HeLa cancer cell lines","author":"Bawane","year":"2025","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.prp.2025.156153_bib65","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.3390\/ijms24043748","article-title":"Natural products as modulators of Nrf2 signaling pathway in neuroprotection","volume":"24","author":"Moratilla-Rivera","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2025.156153_bib66","doi-asserted-by":"crossref","DOI":"10.2174\/0929867330666230504121523","article-title":"Phytochemicals as substances that affect astrogliosis and their implications for the management of neurodegenerative diseases","author":"Forouzanfar","year":"2024","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.prp.2025.156153_bib67","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23477","article-title":"Understanding the role of zingerone on biochemical and behavioral changes in rat brain inflicted with C6 glioma cells","volume":"37","author":"Chopra","year":"2023","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.jksus.2022.101919","article-title":"Antioxidant and antiplasmodial activities of malus sikkimenmsis bioactives and their role in the suppression of LPS-induced neuroinflammation in glial cells","volume":"34","author":"Dixit","year":"2022","journal-title":"J. King Saud. Univ."},{"key":"10.1016\/j.prp.2025.156153_bib69","first-page":"179","article-title":"Assessment of anti-inflammatory activity of quercetin and rosmarinic acid induced by streptozotocin in C6 cells: a comparative study","volume":"28","author":"Jahan","year":"2024","journal-title":"Korean J. Physiol. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib70","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3389\/fphar.2016.00350","article-title":"Therapeutic potential and molecular mechanisms of emblica officinalis gaertn in countering nephrotoxicity in rats induced by the chemotherapeutic agent cisplatin","volume":"7","author":"Malik","year":"2016","journal-title":"Front. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12882-017-0601-y","article-title":"Protective effect of rutin supplementation against cisplatin-induced nephrotoxicity in rats","volume":"18","author":"Alhoshani","year":"2017","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.prp.2025.156153_bib72","first-page":"1","article-title":"Ameliorative effect of vitamin d on CPF toxicity by evaluation of wistar rat liver enzymes and kidney biomarkers","author":"Sanoeva","year":"2025","journal-title":"Casp. J. Environ. Sci."},{"key":"10.1016\/j.prp.2025.156153_bib73","doi-asserted-by":"crossref","first-page":"8892026","DOI":"10.1155\/omcl\/8892026","article-title":"Targeted modulation of mitochondrial oxidative stress ameliorates 5-Fluorouracil-Induced renal injury in BALB\/c mice","volume":"2025","author":"Tambe","year":"2025","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.prp.2025.156153_bib74","doi-asserted-by":"crossref","first-page":"10979","DOI":"10.1038\/s41598-024-81175-7","article-title":"Ferulic acid lipid nano capsules versus its native form in alleviating diabetic nephropathy induced in rats through TGF-\u03b21\/Hippo pathway crosstalk modulation","volume":"15","author":"Zohny","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.prp.2025.156153_bib75","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1007\/s11255-020-02485-z","article-title":"Vinpocetine reduces cisplatin-induced acute kidney injury through inhibition of NF-\u03baB pathway and activation of Nrf2\/ARE pathway in rats","volume":"52","author":"Song","year":"2020","journal-title":"Int. Urol. Nephrol."},{"key":"10.1016\/j.prp.2025.156153_bib76","first-page":"1263","article-title":"Hibiscetin mitigates Cisplatin-evoked renal toxicity through the modulation of activated Caspase-3\/COX-2\/iNOS\/p53","volume":"38","author":"Alqurashi","year":"2024","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"10.1016\/j.prp.2025.156153_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.microb.2024.100084","article-title":"Exploring eucalyptus globulus phytochemicals: analytical, antibacterial, and molecular docking investigations","volume":"3","author":"Sharma","year":"2024","journal-title":"Microbe"},{"key":"10.1016\/j.prp.2025.156153_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2023.137164","article-title":"Green synthesis, molecular structure, spectroscopic, ADME, DFT and molecular docking studies on methyl 10-trans, 12-cis-octadecadienoate","volume":"1300","author":"Ezhilan","year":"2024","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.prp.2025.156153_bib79","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imu.2016.09.004","article-title":"Exploring the physicochemical profile and the binding patterns of selected novel anticancer himalayan plant derived active compounds with macromolecular targets","volume":"5","author":"Gurung","year":"2016","journal-title":"Inform. Med. Unlocked"},{"key":"10.1016\/j.prp.2025.156153_bib80","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.jksus.2019.01.011","article-title":"Molecular docking studies on the interaction of NCI anticancer analogues with human phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit","volume":"31","author":"Arthur","year":"2019","journal-title":"J. King Saud. Univ."},{"key":"10.1016\/j.prp.2025.156153_bib81","article-title":"Recent progress in zein nanoparticles: a promising approach for advancing cancer therapy","volume":"97","author":"Khan","year":"2024","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.prp.2025.156153_bib82","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/967826","article-title":"Pathophysiology of cisplatin-induced acute kidney injury","volume":"2014","author":"Ozkok","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.prp.2025.156153_bib83","doi-asserted-by":"crossref","DOI":"10.1177\/1758835920923430","article-title":"Cisplatin-induced renal toxicity in elderly people","volume":"12","author":"Duan","year":"2020","journal-title":"Ther. Adv. Med. Oncol."},{"key":"10.1016\/j.prp.2025.156153_bib84","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142225","article-title":"Understanding the risk factors and long-term consequences of cisplatin-associated acute kidney injury: an observational cohort study","volume":"10","author":"Bhat","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.prp.2025.156153_bib85","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41581-022-00631-7","article-title":"Cisplatin nephrotoxicity: new insights and therapeutic implications","volume":"19","author":"Tang","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.prp.2025.156153_bib86","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.fct.2017.07.018","article-title":"Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic","volume":"107","author":"Ortega-Dom\u00ednguez","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib87","first-page":"1","article-title":"Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3\/NF-\u03baB\/Bcl-2 signaling pathways in rats and in silico study","author":"Kazmi","year":"2024","journal-title":"Naunyn. Schmiede Arch. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib88","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.toxlet.2012.12.015","article-title":"In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells","volume":"217","author":"Sohn","year":"2013","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.prp.2025.156153_bib89","doi-asserted-by":"crossref","DOI":"10.1002\/prp2.148","article-title":"Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells","volume":"3","author":"Huang","year":"2015","journal-title":"Pharmacol. Res. Perspect."},{"key":"10.1016\/j.prp.2025.156153_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2019.104672","article-title":"Vitamin e protects against cisplatin-induced genotoxicity in human lymphocytes","volume":"62","author":"Al-Eitan","year":"2020","journal-title":"Toxicol. Vitr"},{"key":"10.1016\/j.prp.2025.156153_bib91","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.2174\/1389557519666190320124438","article-title":"Protective role of natural products in cisplatin-induced nephrotoxicity","volume":"19","author":"Ridzuan","year":"2019","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.prp.2025.156153_bib92","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/j.fct.2006.01.013","article-title":"Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research","volume":"44","author":"Ali","year":"2006","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib93","doi-asserted-by":"crossref","DOI":"10.15171\/ipp.2019.07","article-title":"Mechanistic impact of medicinal plants affecting cisplatin-induced nephrotoxicity; an overview","volume":"5","author":"Hooshyar","year":"2019","journal-title":"Immunopathol. Persa"},{"key":"10.1016\/j.prp.2025.156153_bib94","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1080\/01480545.2018.1497050","article-title":"Ameliorative effect of selenium nanoparticles and fish oil on cisplatin and gamma irradiation-induced nephrotoxicity in Male albino rats","volume":"42","author":"Saif-Elnasr","year":"2019","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib95","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22555","article-title":"Anti-apoptotic effect of vinpocetine on cisplatin-induced hepatotoxicity in mice: the role of Annexin-V, Caspase-3, and bax","volume":"34","author":"Habib","year":"2020","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib96","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/biolre\/iox053","article-title":"Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxidant activity","volume":"96","author":"Barberino","year":"2017","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.prp.2025.156153_bib97","doi-asserted-by":"crossref","first-page":"37001","DOI":"10.1117\/1.JBO.21.3.037001","article-title":"Jr, quantifying creatinine and urea in human urine through raman spectroscopy aiming at diagnosis of kidney disease","volume":"21","author":"Saatkamp","year":"2016","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.prp.2025.156153_bib98","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.toxrep.2018.11.006","article-title":"Alterations of blood chemistry, hepatic and renal function, and blood cytometry in acrylamide-treated rats","volume":"5","author":"Rivadeneyra-Dom\u00ednguez","year":"2018","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.prp.2025.156153_bib99","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/nu8090566","article-title":"Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis","volume":"8","author":"Li","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.prp.2025.156153_bib100","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ejphar.2014.12.008","article-title":"Telmisartan ameliorates cisplatin-induced nephrotoxicity by inhibiting MAPK mediated inflammation and apoptosis","volume":"748","author":"Malik","year":"2015","journal-title":"Eur. J. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib101","first-page":"217","article-title":"Urinary cytochrome c and Caspase-3 as novel biomarker of renal function impairment in unilateral ureteropelvic junction obstruction model of wistar rats","author":"Sibarani","year":"2020","journal-title":"Res. Rep. Urol."},{"key":"10.1016\/j.prp.2025.156153_bib102","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.21960","article-title":"Restorative effects of chrysin pretreatment on oxidant\u2013antioxidant status, inflammatory cytokine production, and apoptotic and autophagic markers in acute paracetamol-induced hepatotoxicity in rats: an experimental and biochemical study","volume":"31","author":"Eldutar","year":"2017","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.prp.2025.156153_bib103","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.567852","article-title":"Dibenzazepine attenuates against cisplatin-induced nephrotoxicity in rats: involvement of NOTCH pathway","volume":"11","author":"Abd El-Rhman","year":"2020","journal-title":"Front. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108647","article-title":"Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: impact on inflammation, apoptosis, and autophagy","volume":"112","author":"Sun","year":"2019","journal-title":"Biomed. Pharm."},{"key":"10.1016\/j.prp.2025.156153_bib105","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3390\/biomedicines11030804","article-title":"Hirsutidin prevents cisplatin-evoked renal toxicity by reducing oxidative stress\/inflammation and restoring the endogenous enzymatic and non-enzymatic level","volume":"11","author":"Imam","year":"2023","journal-title":"Biomedicines"}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033825003462?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033825003462?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T14:27:56Z","timestamp":1755095276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033825003462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":105,"alternative-id":["S0344033825003462"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2025.156153","relation":{},"ISSN":["0344-0338"],"issn-type":[{"type":"print","value":"0344-0338"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methyl jasmonate mitigates cisplatin-induced nephrotoxicity via modulation of Caspase-3\/COX-2\/ NF-\u03baB signalling pathway: In silico, In vitro, and In vivo investigations","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2025.156153","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"156153"}}