{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:27:16Z","timestamp":1786505236078,"version":"build-2736575974"},"reference-count":270,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.prp.2026.156601","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T15:46:15Z","timestamp":1783007175000},"page":"156601","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Cuproptosis-mediated metabolic\u2013inflammatory coupling in hypertensive myocardial injury: Mechanistic insights and therapeutic perspectives"],"prefix":"10.1016","volume":"286","author":[{"given":"Yelin","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomin","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2 A","key":"10.1016\/j.prp.2026.156601_bib1","article-title":"Cardiovascular disease in the elderly. Hypertensive cardiovascular disease","volume":"10","author":"Frohlich","year":"1987","journal-title":"J. Am. Coll. Cardiol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib2","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s11906-996-0025-8","article-title":"Hypertensive cardiovascular disease in African Americans","volume":"1","author":"Wali","year":"1999","journal-title":"Curr. Hypertens. Rep."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib3","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1161\/HYPERTENSIONAHA.123.20481","article-title":"Hypertension-driven regulatory t-cell perturbations accelerate myocardial ischemia-reperfusion injury","volume":"80","author":"Sun","year":"2023","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics13010060","article-title":"Prevalence of myocardial injury and myocardial infarction in patients with a hypertensive emergency: a systematic review","volume":"13","author":"Talle","year":"2022","journal-title":"Diagnostics"},{"issue":"20","key":"10.1016\/j.prp.2026.156601_bib5","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1001\/jama.1996.03530440037034","article-title":"The progression from hypertension to congestive heart failure","volume":"275","author":"Levy","year":"1996","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib6","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1161\/01.HYP.35.2.580","article-title":"Continuous relation between left ventricular mass and cardiovascular risk in essential hypertension","volume":"35","author":"Schillaci","year":"2000","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib7","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1161\/CIRCRESAHA.113.300376","article-title":"Cardiac metabolism in heart failure: implications beyond ATP production","volume":"113","author":"Doenst","year":"2013","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1084\/jem.20171773","article-title":"The immunology of hypertension","volume":"215","author":"Norlander","year":"2018","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.prp.2026.156601_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.607089","article-title":"Deciphering the protein, modular connections and precision medicine for heart failure with preserved ejection fraction and hypertension based on TMT quantitative proteomics and molecular docking","volume":"12","author":"Zhou","year":"2021","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-81611-8","article-title":"A multi-omics approach identifies the key role of disorders of sphingolipid metabolism in Ang II-induced hypertensive cardiomyopathy myocardial remodeling","volume":"14","author":"Qu","year":"2024","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25063275","article-title":"Connexin43, a promising target to reduce cardiac arrhythmia burden in pulmonary arterial hypertension","volume":"25","author":"Sykora","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.958368","article-title":"Cuproptosis scoring system to predict the clinical outcome and immune response in bladder cancer","volume":"13","author":"Song","year":"2022","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib13","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.ccell.2025.03.031","article-title":"Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance","volume":"43","author":"Lei","year":"2025","journal-title":"Cancer Cell."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib14","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/s41392-022-01229-y","article-title":"Copper homeostasis and cuproptosis in health and disease","volume":"7","author":"Chen","year":"2022","journal-title":"Signal. Transduct. Target. Ther."},{"key":"10.1016\/j.prp.2026.156601_bib15","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.actbio.2025.07.013","article-title":"A tumor microenvironment-responsive nanocomposite for enhanced copper retention and hypoxia reversal to promote cuproptosis in tumor treatment","volume":"202","author":"Chen","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.prp.2026.156601_bib16","article-title":"Mechanisms of copper metabolism and cuproptosis: implications for liver diseases","volume":"16","author":"Chen","year":"2025","journal-title":"Front. Immunol."},{"issue":"18","key":"10.1016\/j.prp.2026.156601_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26189173","article-title":"Copper, Cuproptosis, and Neurodegenerative Diseases","volume":"26","author":"Genchi","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib18","doi-asserted-by":"crossref","DOI":"10.1111\/bph.70171","article-title":"HMC ameliorates myocardial ischaemia-reperfusion injury through suppressing cuproptosis via the de-ubiquitination and stabilization of ATP7A","author":"Su","year":"2025","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.prp.2026.156601_bib19","article-title":"IL-10 partly mediates the ability of MSC-derived extracellular vesicles to attenuate myocardial damage in experimental metabolic renovascular hypertension","volume":"13","author":"Jiang","year":"2022","journal-title":"Front. Immunol."},{"issue":"39","key":"10.1016\/j.prp.2026.156601_bib20","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000035241","article-title":"Bioinformatics analysis of copper death gene in diabetic immune infiltration","volume":"102","author":"Lu","year":"2023","journal-title":"Medicine"},{"issue":"41","key":"10.1016\/j.prp.2026.156601_bib21","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000031050","article-title":"Bioinformatics analysis identified immune infiltration, risk and drug prediction models of copper-induced death genes involved in salivary glands damage of primary Sj\u00f6gren's syndrome","volume":"101","author":"Zhang","year":"2022","journal-title":"Medicine"},{"key":"10.1016\/j.prp.2026.156601_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123379","article-title":"Metallothionein rescues doxorubicin cardiomyopathy via mitigation of cuproptosis","volume":"363","author":"Liu","year":"2025","journal-title":"Life Sci."},{"key":"10.1016\/j.prp.2026.156601_bib23","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3389\/fphys.2019.00435","article-title":"How Hypertension Affects Heart Metabolism","volume":"10","author":"Polak-Iwaniuk","year":"2019","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib24","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.cardfail.2016.08.001","article-title":"Metabolic Modulation by Medium-Chain Triglycerides Reduces Oxidative Stress and Ameliorates CD36-Mediated Cardiac Remodeling in Spontaneously Hypertensive Rat in the Initial and Established Stages of Hypertrophy","volume":"23","author":"Saifudeen","year":"2017","journal-title":"J. Card. Fail."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.14715\/cmb\/2022.68.7.22","article-title":"miR-1 Mediated AMPK Pathway on Cardiomyocyte Apoptosis in Hypertensive Rats","volume":"68","author":"Huang","year":"2022","journal-title":"Cell. Mol. Biol. (Noisy-le. -Grand. Fr. )"},{"issue":"18","key":"10.1016\/j.prp.2026.156601_bib26","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.70072","article-title":"Hypertension and obesity independently drive hypertrophy and alter mitochondrial metabolism in a mouse model of heart failure with preserved ejection fraction","volume":"12","author":"Werbner","year":"2024","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.prp.2026.156601_bib27","article-title":"The Impact of Obesity on Cardiac Energy Metabolism and Efficiency in Heart Failure With Preserved Ejection Fraction","author":"Ketema","year":"2025","journal-title":"Can. J. Cardiol."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib28","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1007\/s00109-010-0663-9","article-title":"Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease","volume":"88","author":"Ren","year":"2010","journal-title":"J. Mol. Med. (Berl. Ger. )"},{"issue":"8","key":"10.1016\/j.prp.2026.156601_bib29","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1093\/cvr\/cvy063","article-title":"Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice","volume":"114","author":"Umbarawan","year":"2018","journal-title":"Cardiovasc. Res."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib30","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.015154","article-title":"Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats","volume":"9","author":"Li","year":"2020","journal-title":"J. Am. Heart Assoc."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib31","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.026950","article-title":"Progressive Cardiac Metabolic Defects Accompany Diastolic and Severe Systolic Dysfunction in Spontaneously Hypertensive Rat Hearts","volume":"12","author":"Li","year":"2023","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.prp.2026.156601_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2024.112254","article-title":"Exogenous thyroxine increases cardiac GLUT4 translocation in insulin resistant OLETF rats","volume":"590","author":"Mendez","year":"2024","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.prp.2026.156601_bib33","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/282984","article-title":"Muscle IGF-1-induced skeletal muscle hypertrophy evokes higher insulin sensitivity and carbohydrate use as preferential energy substrate","volume":"2015","author":"Christoffolete","year":"2015","journal-title":"BioMed. Res. Int."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib34","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/gerona\/glab260","article-title":"Age-Related Increase in Lactate Dehydrogenase Activity in Skeletal Muscle Reduces Life Span in Drosophila","volume":"77","author":"Hunt","year":"2022","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib35","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.yjmcc.2020.01.004","article-title":"Metabolic impairment in response to early induction of C\/EBP\u03b2 leads to compromised cardiac function during pathological hypertrophy","volume":"139","author":"Banerjee","year":"2020","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.prp.2026.156601_bib36","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2024.1336551","article-title":"Cardiac fibrogenesis: an immuno-metabolic perspective","volume":"15","author":"Hoque","year":"2024","journal-title":"Front. Physiol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib37","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s10741-014-9457-4","article-title":"Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart","volume":"20","author":"Akhmedov","year":"2015","journal-title":"Heart Fail. Rev."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib38","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/MNH.0000000000000771","article-title":"Mitochondrial deacetylase Sirt3 in vascular dysfunction and hypertension","volume":"31","author":"Dikalov","year":"2022","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2337\/db15-0399","article-title":"ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity","volume":"65","author":"Patel","year":"2016","journal-title":"Diabetes"},{"key":"10.1016\/j.prp.2026.156601_bib40","doi-asserted-by":"crossref","DOI":"10.1097\/FJC.0000000000001757","article-title":"Omaveloxolone promotes macrophage M2 polarization by activating the NRF2-Keap1 pathway and improves myocardial remodeling induced by pressure overload","author":"Li","year":"2025","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib41","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jacc.2005.04.040","article-title":"Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension","volume":"46","author":"Perticone","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib42","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ijcard.2008.12.131","article-title":"Endothelial dysfunction, ADMA and insulin resistance in essential hypertension","volume":"142","author":"Perticone","year":"2010","journal-title":"Int. J. Cardiol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib43","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1161\/01.HYP.0000047668.48494.39","article-title":"Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease","volume":"41","author":"De Las Fuentes","year":"2003","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib44","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000369782","article-title":"Remodeling of glucose metabolism precedes pressure overload-induced left ventricular hypertrophy: review of a hypothesis","volume":"130","author":"Kundu","year":"2015","journal-title":"Cardiology"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib45","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12933-017-0528-4","article-title":"Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes","volume":"16","author":"Gonz\u00e1lez","year":"2017","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.prp.2026.156601_bib46","article-title":"An Effective Sodium-Dependent Glucose Transporter 2 Inhibition, Canagliflozin, Prevents Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats","volume":"13","author":"He","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.prp.2026.156601_bib47","doi-asserted-by":"crossref","first-page":"5191","DOI":"10.1007\/s10787-025-01897-6","article-title":"The protective effects of coenzyme Q10 on blood pressure: a narrative review of anti-inflammatory and antioxidant mechanisms","volume":"33","author":"Hosseini Roknabadi","year":"2025","journal-title":"Inflammopharmacology"},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib48","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1038\/s41418-023-01125-0","article-title":"Cuproptosis: p53-regulated metabolic cell death?","volume":"30","author":"Xiong","year":"2023","journal-title":"Cell. Death Differ."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib49","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/ajh\/hpaa202","article-title":"Renovascular Hypertension Induces Myocardial Mitochondrial Damage, Contributing to Cardiac Injury and Dysfunction in Pigs With Metabolic Syndrome","volume":"34","author":"Nargesi","year":"2021","journal-title":"Am. J. Hypertens."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib50","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.003118","article-title":"Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension","volume":"5","author":"Eirin","year":"2016","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.prp.2026.156601_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.868365","article-title":"Potential Role of Lisinopril in Reducing Atherosclerotic Risk: Evidence of an Antioxidant Effect in Human Cardiomyocytes Cell Line","volume":"13","author":"Scisciola","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib52","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jgr.2024.11.003","article-title":"Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms","volume":"49","author":"Mu","year":"2025","journal-title":"J. Ginseng Res."},{"key":"10.1016\/j.prp.2026.156601_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123119","article-title":"Mitigation of ischemia\/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation","volume":"318","author":"Chen","year":"2025","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.prp.2026.156601_bib54","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1007\/s12012-025-10034-2","article-title":"Chronic Anatabine Administration Attenuates Cardiovascular Activity by Targeting NF-\u03baB\/NLRP3\/Caspase-1-Dependent Pyroptosis and Oxidative Stress in Paraventricular Nucleus of Hypertensive Rat","volume":"25","author":"Su","year":"2025","journal-title":"Cardiovasc. Toxicol."},{"issue":"9","key":"10.1016\/j.prp.2026.156601_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e19399","article-title":"Dietary carotenoids to improve hypertension","volume":"9","author":"Abbasian","year":"2023","journal-title":"Heliyon"},{"issue":"Pt A","key":"10.1016\/j.prp.2026.156601_bib56","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.neuropharm.2016.11.010","article-title":"Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats","volume":"113","author":"Sun","year":"2017","journal-title":"Neuropharmacology"},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib57","doi-asserted-by":"crossref","DOI":"10.3390\/genes14101876","article-title":"Role of Mitochondrial Dynamics in Heart Diseases","volume":"14","author":"Tokuyama","year":"2023","journal-title":"Genes"},{"key":"10.1016\/j.prp.2026.156601_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118936","article-title":"Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes","volume":"268","author":"Ordog","year":"2021","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib59","article-title":"LTBP2 knockdown by siRNA reverses myocardial oxidative stress injury, fibrosis and remodelling during dilated cardiomyopathy","volume":"228","author":"Pang","year":"2020","journal-title":"Acta Physiol. (Oxf. Engl. )"},{"issue":"18","key":"10.1016\/j.prp.2026.156601_bib60","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.21037\/atm-20-6015","article-title":"Etomidate alleviates cardiac dysfunction, fibrosis and oxidative stress in rats with myocardial ischemic reperfusion injury","volume":"8","author":"Xie","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.prp.2026.156601_bib61","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3389\/fcell.2020.00413","article-title":"The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy","volume":"8","author":"Wang","year":"2020","journal-title":"Front. Cell. Dev. Biol."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib62","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/s41418-020-00657-z","article-title":"Functions of outer mitochondrial membrane proteins: mediating the crosstalk between mitochondrial dynamics and mitophagy","volume":"28","author":"Xian","year":"2021","journal-title":"Cell. Death Differ."},{"key":"10.1016\/j.prp.2026.156601_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116337","article-title":"The Janus face of mitophagy in myocardial ischemia\/reperfusion injury and recovery","volume":"173","author":"Deng","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.prp.2026.156601_bib64","article-title":"The Role of Mitochondria in Liver Ischemia-Reperfusion Injury: From Aspects of Mitochondrial Oxidative Stress, Mitochondrial Fission, Mitochondrial Membrane Permeable Transport Pore Formation, Mitophagy, and Mitochondria-Related Protective Measures","volume":"2021","author":"Zhang","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib65","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/acel.12650","article-title":"The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore","volume":"16","author":"Rottenberg","year":"2017","journal-title":"Aging Cell."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/biology13020070","article-title":"Mitochondrial Dysfunction in Endothelial Progenitor Cells: Unraveling Insights from Vascular Endothelial Cells","volume":"13","author":"Kulovic-Sissawo","year":"2024","journal-title":"Biology"},{"issue":"15","key":"10.1016\/j.prp.2026.156601_bib67","doi-asserted-by":"crossref","first-page":"3476","DOI":"10.1111\/bph.70032","article-title":"Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells","volume":"182","author":"Lin","year":"2025","journal-title":"Br. J. Pharmacol."},{"issue":"6586","key":"10.1016\/j.prp.2026.156601_bib68","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1126\/science.abf0529","article-title":"Copper induces cell death by targeting lipoylated TCA cycle proteins","volume":"375","author":"Tsvetkov","year":"2022","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib69","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.18632\/aging.206251","article-title":"Age-associated changes in the heart: implications for COVID-19 therapies","volume":"17","author":"Wood","year":"2025","journal-title":"Aging (Albany NY)"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib70","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s11596-024-2832-z","article-title":"Copper Metabolism and Cuproptosis: Molecular Mechanisms and Therapeutic Perspectives in Neurodegenerative Diseases","volume":"44","author":"Ban","year":"2024","journal-title":"Curr. Med. Sci."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib71","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s40364-024-00677-8","article-title":"Copper homeostasis and copper-induced cell death in tumor immunity: implications for therapeutic strategies in cancer immunotherapy","volume":"12","author":"Zhang","year":"2024","journal-title":"Biomark. Res."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib72","first-page":"916","article-title":"Biological applications of copper-containing materials","volume":"6","author":"Wang","year":"2021","journal-title":"Bioact. Mater."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib73","first-page":"143","article-title":"Biological role of copper as an essential trace element in the human organism","volume":"67","author":"Vetch\u00fd","year":"2018","journal-title":"Ceska a Slov. Farm. Cas. Ceske Farm. Spol. a Slov. Farm. Spol."},{"key":"10.1016\/j.prp.2026.156601_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2025.107042","article-title":"From cell death to neurological disease: Unraveling the role of copper","volume":"214","author":"Gao","year":"2025","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib75","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s12672-025-02335-3","article-title":"Research progress on cuproptosis and copper related anti-tumor therapy","volume":"16","author":"Li","year":"2025","journal-title":"Discov. Oncol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib76","first-page":"390","article-title":"Copper and metallothioneins in cancer cells","volume":"58","author":"Floria\u0144czyk","year":"2003","journal-title":"Ann. Univ. Mariae Curie-Sklodowska Sect. D Med."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib77","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.molcel.2022.05.001","article-title":"Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death","volume":"82","author":"Cobine","year":"2022","journal-title":"Mol. Cell."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib78","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.bpj.2022.02.033","article-title":"Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion","volume":"121","author":"Walke","year":"2022","journal-title":"Biophys. J."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib79","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1007\/s00424-020-02412-2","article-title":"The molecular mechanisms of copper metabolism and its roles in human diseases","volume":"472","author":"Chen","year":"2020","journal-title":"Pflug. Arch. Eur. J. Physiol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib80","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/10641963.2021.1969662","article-title":"Anthropometric indices of obesity as predictors of high blood pressure among school children","volume":"44","author":"Al Hourani","year":"2022","journal-title":"Clin. Exp. Hypertens."},{"issue":"1 Pt C","key":"10.1016\/j.prp.2026.156601_bib81","article-title":"Hypertension and Lorundrostat: Key Discoveries From the TARGET-HTN Trial","volume":"49","author":"Irfan","year":"2024","journal-title":"Curr. Probl. Cardiol."},{"key":"10.1016\/j.prp.2026.156601_bib82","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/B978-0-444-59565-2.00045-9","article-title":"Inborn errors of copper metabolism","volume":"113","author":"KALER","year":"2013","journal-title":"Handb. Clin. Neurol."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib83","doi-asserted-by":"crossref","DOI":"10.3892\/ijmm.2025.5595","article-title":"SDF2 promotes glioma progression via GRP78\u2011mediated ERAD and copper homeostasis disruption","volume":"56","author":"Li","year":"2025","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.prp.2026.156601_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2025.117257","article-title":"Complanatoside A disrupts copper homeostasis and induces cuproptosis via directly targeting ATOX1 in prostate cancer","volume":"496","author":"Zhao","year":"2025","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.prp.2026.156601_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123538","article-title":"Lactate metabolism regulating nanosystem synergizes cuproptosis and ferroptosis to enhance cancer immunotherapy","volume":"325","author":"Zhi","year":"2026","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib86","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12967-025-06163-5","article-title":"MT2A promotes angiogenesis in chronically ischemic brains through a copper-mitochondria regulatory mechanism","volume":"23","author":"Mo","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.prp.2026.156601_bib87","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.freeradbiomed.2025.01.042","article-title":"Identification of a novel cuproptosis inducer that induces ER stress and oxidative stress to trigger immunogenic cell death in tumors","volume":"229","author":"Ning","year":"2025","journal-title":"Free. Radic. Biol. & Med."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib88","doi-asserted-by":"crossref","first-page":"C1320","DOI":"10.1152\/ajpcell.00466.2022","article-title":"PTPMT1 protects cardiomyocytes from necroptosis induced by \u03b3-ray irradiation through alleviating mitochondria injury","volume":"324","author":"Yi","year":"2023","journal-title":"Am. J. Physiol. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib89","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1002\/jnr.10537","article-title":"Neurotoxicity from glutathione depletion is dependent on extracellular trace copper","volume":"71","author":"White","year":"2003","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.prp.2026.156601_bib90","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.actbio.2025.06.018","article-title":"Janus hydrogels delivering low-density lipoprotein receptor-related protein 6 inhibitor enhance myocardial repair via m6A-dependent cuproptosis in bama pigs","volume":"201","author":"Liu","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.prp.2026.156601_bib91","doi-asserted-by":"crossref","DOI":"10.1007\/s11010-025-05340-w","article-title":"Emerging trends in cardiovascular diseases: the impact of ferroptosis and cuproptosis on cardiomyocyte death","author":"Chen","year":"2025","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.prp.2026.156601_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107739","article-title":"Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis","volume":"216","author":"Kong","year":"2025","journal-title":"Pharmacol. Res."},{"issue":"37","key":"10.1016\/j.prp.2026.156601_bib93","article-title":"Oligocopper-Loaded Lipoic Acid Nanoparticles Promote Mitochondrial Protein Lipoylation for Augmented Cuproptosis Therapy","volume":"21","author":"Chen","year":"2025","journal-title":"Small (Weinh. der Bergstr. Ger. )"},{"key":"10.1016\/j.prp.2026.156601_bib94","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2025.1555858","article-title":"Copper metabolism and cuproptosis: broad perspectives in the treatment of hepatocellular carcinoma","volume":"15","author":"Liang","year":"2025","journal-title":"Front. Oncol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib95","doi-asserted-by":"crossref","first-page":"H475","DOI":"10.1152\/ajpheart.00573.2020","article-title":"The role of diet-derived short-chain fatty acids in regulating cardiac pressure overload","volume":"320","author":"Pakhomov","year":"2021","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"16","key":"10.1016\/j.prp.2026.156601_bib96","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.249201","article-title":"Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1","volume":"133","author":"Curnock","year":"2020","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib97","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.freeradbiomed.2025.06.017","article-title":"Phillygenin ameliorates myocardial ischemia-reperfusion injury by inhibiting cuproptosis via the autophagy-lysosome degradation of CTR1","volume":"237","author":"Chen","year":"2025","journal-title":"Free. Radic. Biol. & Med."},{"key":"10.1016\/j.prp.2026.156601_bib98","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2023.1154920","article-title":"Identification of cuproptosis-related biomarkers in dilated cardiomyopathy and potential therapeutic prediction of herbal medicines","volume":"10","author":"Bian","year":"2023","journal-title":"Front. Mol. Biosci."},{"issue":"11-12","key":"10.1016\/j.prp.2026.156601_bib99","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1007\/s10495-024-02021-9","article-title":"Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP\/ATP7A signaling","volume":"29","author":"Chen","year":"2024","journal-title":"Apoptosis"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib100","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-28342-6","article-title":"The effect of cuproptosis-related gene Atox1 on cardiac hypertrophy in heart failure was investigated based on bioinformatics analysis","volume":"15","author":"Zhou","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.prp.2026.156601_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2026.105115","article-title":"IGF2BP2 promotes cuproptosis of cardiomyocytes through m(6)A modification of MAP2K1 in sepsis-induced myocardial injury","volume":"425","author":"Chen","year":"2026","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.prp.2026.156601_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114830","article-title":"The molecular mechanisms of cuproptosis and its relevance to cardiovascular disease","volume":"163","author":"Wang","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib103","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24021667","article-title":"ATF3\/SPI1\/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury","volume":"24","author":"Huo","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib104","doi-asserted-by":"crossref","first-page":"11849","DOI":"10.2147\/DDDT.S562664","article-title":"Copper-Induced Cell Death in Renal Diseases: Molecular Mechanisms and Therapeutic Implications","volume":"19","author":"Lv","year":"2025","journal-title":"Drug. Des. Devel Ther."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib105","first-page":"965","article-title":"[The advancement of cuproptosis in hematological tumors]","volume":"45","author":"Zhou","year":"2024","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib106","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s00018-024-05358-1","article-title":"Mitochondrial copper overload promotes renal fibrosis via inhibiting pyruvate dehydrogenase activity","volume":"81","author":"Zhu","year":"2024","journal-title":"Cell. Mol. life Sci. CMLS"},{"key":"10.1016\/j.prp.2026.156601_bib107","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.951597","article-title":"Perspectives for Forkhead box transcription factors in diabetic cardiomyopathy: Their therapeutic potential and possible effects of salvianolic acids","volume":"9","author":"Han","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.prp.2026.156601_bib108","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103787","article-title":"Decoding Parkinson's Disease: The interplay of cell death pathways, oxidative stress, and therapeutic innovations","volume":"85","author":"Liu","year":"2025","journal-title":"Redox Biol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib109","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/FJC.0000000000001653","article-title":"The Research Progress: Cuproptosis and Copper Metabolism in Regulating Cardiovascular Diseases","volume":"85","author":"Yanjuan","year":"2025","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib110","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/FJC.0000000000001455","article-title":"Cooling Down Inflammation in the Cardiovascular System via the Nicotinic Acetylcholine Receptor","volume":"82","author":"Kaplan","year":"2023","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib111","doi-asserted-by":"crossref","first-page":"H1775","DOI":"10.1152\/ajpheart.00305.2002","article-title":"Structural, functional, and molecular characterization of the SHHF model of heart failure","volume":"283","author":"Heyen","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib112","article-title":"Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction","volume":"30","author":"Meng","year":"2025","journal-title":"Front. Biosci. (Landmark Ed. )"},{"key":"10.1016\/j.prp.2026.156601_bib113","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.732952","article-title":"ADAM17, A Key Player of Cardiac Inflammation and Fibrosis in Heart Failure Development During Chronic Catecholamine Stress","volume":"9","author":"Adu-Amankwaah","year":"2021","journal-title":"Front. Cell. Dev. Biol."},{"key":"10.1016\/j.prp.2026.156601_bib114","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.exppara.2016.05.005","article-title":"Innate immunomodulation to trypanosomatid parasite infections","volume":"167","author":"Dos-Santos","year":"2016","journal-title":"Exp. Parasitol."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib115","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s11906-017-0740-3","article-title":"Androgens and Hypertension in Men and Women: a Unifying View","volume":"19","author":"Moretti","year":"2017","journal-title":"Curr. Hypertens. Rep."},{"issue":"9","key":"10.1016\/j.prp.2026.156601_bib116","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1016\/j.jse.2020.01.076","article-title":"RAGE-dependent NF-kB inflammation processes in the capsule of frozen shoulders","volume":"29","author":"Yano","year":"2020","journal-title":"J. Shoulder Elb. Surg."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib117","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/s41420-022-01073-7","article-title":"Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB\/AP-1 pathway and TLR4 expression","volume":"8","author":"Li","year":"2022","journal-title":"Cell. death Discov."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib118","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23738","article-title":"Biochanin A mitigates ulcerative colitis and intestinal inflammation in mice by inhibiting MAPK\/NF-kB (p65) axis","volume":"38","author":"Kulhari","year":"2024","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib119","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/s41590-021-00886-5","article-title":"NLRP3 inflammasome in cancer and metabolic diseases","volume":"22","author":"Sharma","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.prp.2026.156601_bib120","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115316","article-title":"Pivotal regulatory roles of traditional Chinese medicine in ischemic stroke via inhibition of NLRP3 inflammasome","volume":"294","author":"Tao","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib121","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1007\/s11010-023-04812-1","article-title":"Mitochondria and NLRP3 inflammasome in cardiac hypertrophy","volume":"479","author":"Yan","year":"2024","journal-title":"Mol. Cell. Biochem."},{"issue":"Pt 1","key":"10.1016\/j.prp.2026.156601_bib122","article-title":"Qian Yang Yu Yin Granule prevents hypertensive cardiac remodeling by inhibiting NLRP3 inflammasome activation via Nrf2","volume":"337","author":"Xu","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib123","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1080\/13880209.2021.1953541","article-title":"Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats","volume":"59","author":"Lu","year":"2021","journal-title":"Pharm. Biol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib124","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e17099","article-title":"IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarction","volume":"9","author":"Ma","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.prp.2026.156601_bib125","article-title":"Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis","author":"Amrute","year":"2023","journal-title":"Res. Sq."},{"key":"10.1016\/j.prp.2026.156601_bib126","doi-asserted-by":"crossref","first-page":"5431","DOI":"10.2147\/DDDT.S282206","article-title":"Xanthohumol Inhibits TGF-\u03b21-Induced Cardiac Fibroblasts Activation via Mediating PTEN\/Akt\/mTOR Signaling Pathway [J","volume":"14","author":"Jiang","year":"2020","journal-title":"Drug. Des. Devel Ther."},{"key":"10.1016\/j.prp.2026.156601_bib127","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.yjmcc.2025.01.003","article-title":"Sacubitril\/valsartan attenuates inflammation and myocardial fibrosis in Takotsubo-like cardiomyopathy","volume":"200","author":"Kuang","year":"2025","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib128","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1042\/BJ20131501","article-title":"Involvement of monocytes\/macrophages as key factors in the development and progression of cardiovascular diseases","volume":"458","author":"Fern\u00e1ndez-Velasco","year":"2014","journal-title":"Biochem. J."},{"issue":"13","key":"10.1016\/j.prp.2026.156601_bib129","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1113\/JP283346","article-title":"Intercellular model predicts mechanisms of inflammation-fibrosis coupling after myocardial infarction","volume":"601","author":"Chowkwale","year":"2023","journal-title":"J. Physiol."},{"issue":"13","key":"10.1016\/j.prp.2026.156601_bib130","first-page":"1007","article-title":"Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy","volume":"98","author":"Kuusisto","year":"2012","journal-title":"Heart (Br. Card. Soc. )"},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib131","first-page":"5063","article-title":"Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy","volume":"9","author":"Fang","year":"2017","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.prp.2026.156601_bib132","article-title":"Metabolic Homeostasis of Immune Cells Modulates Cardiovascular Diseases","volume":"8","author":"Li","year":"2025","journal-title":"Res. (Wash. DC)"},{"key":"10.1016\/j.prp.2026.156601_bib133","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.742178","article-title":"Inflammation in Metabolic Cardiomyopathy","volume":"8","author":"Wenzl","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"issue":"8","key":"10.1016\/j.prp.2026.156601_bib134","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1016\/j.bbadis.2018.04.022","article-title":"NF-\u03baB-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis","volume":"1864","author":"Remels","year":"2018","journal-title":"Biochim. Et. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.prp.2026.156601_bib135","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3389\/fphys.2019.00208","article-title":"Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period","volume":"10","author":"Lock","year":"2019","journal-title":"Front. Physiol."},{"issue":"19","key":"10.1016\/j.prp.2026.156601_bib136","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1161\/CIRCULATIONAHA.122.062984","article-title":"Single-Cell RNA Sequencing Reveals Metabolic Stress-Dependent Activation of Cardiac Macrophages in a Model of Dyslipidemia-Induced Diastolic Dysfunction","volume":"150","author":"Panico","year":"2024","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib137","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jtcme.2023.08.004","article-title":"Phytoformulation with hydroxycitric acid and capsaicin protects against high-fat-diet-induced obesity cardiomyopathy by reducing cardiac lipid deposition and ameliorating inflammation and apoptosis in the heart","volume":"14","author":"Uddandrao","year":"2024","journal-title":"J. Tradit. Complement. Med."},{"key":"10.1016\/j.prp.2026.156601_bib138","article-title":"Interferon gamma signaling drives cardiac metabolic rewiring","author":"Melika","year":"2025","journal-title":"bioRxiv Prepr. Serv. Biol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib139","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1042\/BCJ20190472","article-title":"The NLRP3 inflammasome regulates adipose tissue metabolism","volume":"477","author":"Barra","year":"2020","journal-title":"Biochem. J."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib140","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s12265-025-10593-3","article-title":"Targeting Lactic Acid Modification in Ischemic Heart Diseases: Novel Therapeutics and Mechanism","volume":"18","author":"Wan","year":"2025","journal-title":"J. Cardiovasc. Transl. Res."},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib141","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1161\/CIRCRESAHA.122.320488","article-title":"Histone Lactylation Boosts Reparative Gene Activation Post-Myocardial Infarction","volume":"131","author":"Wang","year":"2022","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib142","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s10557-024-07545-5","article-title":"Metabolism Serves as a Bridge Between Cardiomyocytes and Immune Cells in Cardiovascular Diseases","volume":"39","author":"Hang","year":"2025","journal-title":"Cardiovasc. Drugs Ther."},{"key":"10.1016\/j.prp.2026.156601_bib143","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102757","article-title":"Intercellular communication after myocardial infarction: Macrophage as the centerpiece","volume":"109","author":"Li","year":"2025","journal-title":"Ageing Res. Rev."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib144","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/s41385-020-00356-5","article-title":"Macrophage metabolic reprogramming during chronic lung disease","volume":"14","author":"Ogger","year":"2021","journal-title":"Mucosal Immunol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib145","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1161\/CIRCRESAHA.119.312321","article-title":"Obesity, Hypertension, and Cardiac Dysfunction: Novel Roles of Immunometabolism in Macrophage Activation and Inflammation","volume":"126","author":"Mouton","year":"2020","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib146","doi-asserted-by":"crossref","first-page":"4658","DOI":"10.1080\/21655979.2021.2024956","article-title":"microRNA-135a-5p regulates NOD-like receptor family pyrin domain containing 3 inflammasome-mediated hypertensive cardiac inflammation and fibrosis via thioredoxin-interacting protein","volume":"13","author":"Chen","year":"2022","journal-title":"Bioengineered"},{"key":"10.1016\/j.prp.2026.156601_bib147","article-title":"Energy metabolism in cardiovascular diseases: unlocking the hidden powerhouse of cardiac pathophysiology","volume":"16","author":"Chen","year":"2025","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib148","doi-asserted-by":"crossref","DOI":"10.3390\/cells9071565","article-title":"Mitochondrial Dysfunction and Inflammaging in Heart Failure: Novel Roles of CYP-Derived Epoxylipids","volume":"9","author":"Keshavarz-Bahaghighat","year":"2020","journal-title":"Cells"},{"issue":"12","key":"10.1016\/j.prp.2026.156601_bib149","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1007\/s00424-020-02458-2","article-title":"Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts","volume":"472","author":"Wu","year":"2020","journal-title":"Pflug. Arch."},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib150","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1007\/s00424-020-02435-9","article-title":"Reduced nNOS activity is responsible for impaired fatty acid-dependent mitochondrial oxygen consumption in atrial myocardium from hypertensive rat","volume":"472","author":"Wu","year":"2020","journal-title":"Pflug. Arch."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib151","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.258964","article-title":"Insulin-stimulated adipocytes secrete lactate to promote endothelial fatty acid uptake and transport","volume":"135","author":"Ibrahim","year":"2022","journal-title":"J. Cell. Sci."},{"issue":"18","key":"10.1016\/j.prp.2026.156601_bib152","doi-asserted-by":"crossref","DOI":"10.1172\/JCI186420","article-title":"MASH: the nexus of metabolism, inflammation, and fibrosis","volume":"135","author":"Steinberg","year":"2025","journal-title":"J. Clin. Invest."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib153","doi-asserted-by":"crossref","first-page":"E853","DOI":"10.1152\/ajpendo.00251.2013","article-title":"Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages","volume":"305","author":"Jin","year":"2013","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib154","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1007\/s00125-010-1684-1","article-title":"Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009","volume":"53","author":"Defronzo","year":"2010","journal-title":"Diabetologia"},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib155","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/nm834","article-title":"Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy","volume":"9","author":"Hammes","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.prp.2026.156601_bib156","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.104633","article-title":"Oral administration of spa-derived green alga improves insulin resistance in overweight subjects: Mechanistic insights from fructose-fed rats","volume":"152","author":"Kaseda","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"23","key":"10.1016\/j.prp.2026.156601_bib157","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25235591","article-title":"The Development of Maillard Reaction, and Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling Inhibitors as Novel Therapeutic Strategies for Patients with AGE-Related Diseases","volume":"25","author":"Shen","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.prp.2026.156601_bib158","doi-asserted-by":"crossref","first-page":"690","DOI":"10.3389\/fphys.2020.00690","article-title":"Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice","volume":"11","author":"Moore","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.prp.2026.156601_bib159","article-title":"Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation","volume":"15","author":"Cao","year":"2024","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib160","doi-asserted-by":"crossref","first-page":"94","DOI":"10.5114\/reum.2017.67605","article-title":"The human body as an energetic hybrid? New perspectives for chronic disease treatment?","volume":"55","author":"Gajewski","year":"2017","journal-title":"Reumatologia"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib161","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10863-020-09867-z","article-title":"Simvastatin protects heart function and myocardial energy metabolism in pulmonary arterial hypertension induced right heart failure","volume":"53","author":"Tang","year":"2021","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.prp.2026.156601_bib162","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.jes.2023.02.040","article-title":"Polystyrene nanoplastics induce glycolipid metabolism disorder via NF-\u03baB and MAPK signaling pathway in mice","volume":"137","author":"Fan","year":"2024","journal-title":"J. Environ. Sci. (China)"},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib163","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19113634","article-title":"Scutellariae Radix and Coptidis Rhizoma Improve Glucose and Lipid Metabolism in T2DM Rats via Regulation of the Metabolic Profiling and MAPK\/PI3K\/Akt Signaling Pathway","volume":"19","author":"Cui","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib164","doi-asserted-by":"crossref","DOI":"10.1021\/acsami.5c19664","article-title":"Mitochondrial-Targeting Drug-Loaded Nanoparticles Reprogram Macrophage Metabolism via ROS\/NO Co-elimination for Diabetic Wound Healing","author":"Zhou","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.prp.2026.156601_bib165","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2022.100462","article-title":"Cellular and immunometabolic mechanisms of inflammation in depression: Preliminary findings from single cell RNA sequencing and a tribute to Bruce McEwen","volume":"19","author":"Bekhbat","year":"2022","journal-title":"Neurobiol. Stress."},{"key":"10.1016\/j.prp.2026.156601_bib166","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mito.2023.07.002","article-title":"Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function","volume":"72","author":"Blagov","year":"2023","journal-title":"Mitochondrion"},{"issue":"19","key":"10.1016\/j.prp.2026.156601_bib167","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1042\/CS20256705","article-title":"Double-edged mitophagy: balancing inflammation and resolution in lung disease","volume":"139","author":"Tian","year":"2025","journal-title":"Clin. Sci. (Lond. )"},{"key":"10.1016\/j.prp.2026.156601_bib168","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.789267","article-title":"Mitochondrial Metabolism in Myocardial Remodeling and Mechanical Unloading: Implications for Ischemic Heart Disease","volume":"8","author":"Jiang","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.prp.2026.156601_bib169","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/9743280","article-title":"NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia\/Reperfusion Injury in Diabetic Rats","volume":"2017","author":"Qiu","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib170","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1039\/C2FO30228D","article-title":"Protective effects of Houttuynia cordata aqueous extract in mice consuming a high saturated fat diet","volume":"4","author":"Lin","year":"2013","journal-title":"Food & Funct."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib171","doi-asserted-by":"crossref","DOI":"10.3390\/jcm6070071","article-title":"Evidence of Oxidative Stress and Secondary Mitochondrial Dysfunction in Metabolic and Non-Metabolic Disorders","volume":"6","author":"Stepien","year":"2017","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.prp.2026.156601_bib172","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/bs.pmbts.2016.12.012","article-title":"Therapeutic Strategies for Mitochondrial Dysfunction and Oxidative Stress in Age-Related Metabolic Disorders","volume":"146","author":"Bhatti","year":"2017","journal-title":"Progress. Mol. Biol. Transl. Sci."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib173","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1113\/JP279310","article-title":"Delayed metabolic dysfunction in myocardium following exertional heat stroke in mice","volume":"598","author":"Laitano","year":"2020","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib174","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.bbadis.2014.06.030","article-title":"Interplay of oxidative, nitrosative\/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy","volume":"1852","author":"Varga","year":"2015","journal-title":"Biochim. Et. Biophys. Acta"},{"key":"10.1016\/j.prp.2026.156601_bib175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176327","article-title":"Pharmacological inhibition of ICOS attenuates the protective effect of exercise on cardiac fibrosis induced by isoproterenol","volume":"965","author":"Peng","year":"2024","journal-title":"Eur. J. Pharmacol."},{"issue":"19","key":"10.1016\/j.prp.2026.156601_bib176","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21197165","article-title":"Innate Immunity Effector Cells as Inflammatory Drivers of Cardiac Fibrosis","volume":"21","author":"Baci","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib177","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1529756","article-title":"Epigenetic regulation of transcription factors involved in NLRP3 inflammasome and NF-kB signaling pathways","volume":"16","author":"Kaszycki","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.prp.2026.156601_bib178","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.3389\/fphar.2018.01572","article-title":"Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation","volume":"9","author":"Samokhvalov","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"13","key":"10.1016\/j.prp.2026.156601_bib179","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.034805","article-title":"Checkpoint Kinase 1 Stimulates Endogenous Cardiomyocyte Renewal and Cardiac Repair by Binding to Pyruvate Kinase Isoform M2C-Domain and Activating Cardiac Metabolic Reprogramming in a Porcine Model of Myocardial Ischemia\/Reperfusion Injury","volume":"13","author":"Wei","year":"2024","journal-title":"J. Am. Heart Assoc."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib180","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-80505-z","article-title":"Catalpol improved energy metabolism and inflammation through the SIRT5-mediated signaling pathway to ameliorate myocardial injury","volume":"14","author":"Zheng","year":"2024","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib181","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1007\/s12011-024-04345-8","article-title":"Copper Toxicity in Animals: A Review","volume":"203","author":"Wang","year":"2025","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.prp.2026.156601_bib182","doi-asserted-by":"crossref","DOI":"10.1016\/j.prostaglandins.2022.106650","article-title":"Sexual dimorphism in renal heme oxygenase-1 and arachidonic acid metabolizing enzymes in spontaneously hypertensive rats versus normotensive Wistar Kyoto rats","volume":"161","author":"Alhashim","year":"2022","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.prp.2026.156601_bib183","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.685996","article-title":"Predominance of Heart Failure With Preserved Ejection Fraction in Postmenopausal Women: Intra- and Extra-Cardiomyocyte Maladaptive Alterations Scaffolded by Estrogen Deficiency","volume":"9","author":"Adekunle","year":"2021","journal-title":"Front. Cell. Dev. Biol."},{"issue":"12","key":"10.1016\/j.prp.2026.156601_bib184","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1016\/j.mayocp.2021.08.009","article-title":"The Renin-Angiotensin-Aldosterone System in Postmenopausal Women: The Promise of Hormone Therapy","volume":"96","author":"Gersh","year":"2021","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.prp.2026.156601_bib185","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123688","article-title":"Metal ions-induced programmed cell death: how does oxidative stress regulate cell death?","volume":"374","author":"Wang","year":"2025","journal-title":"Life Sci."},{"key":"10.1016\/j.prp.2026.156601_bib186","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2024.1243629","article-title":"Copper homeostasis dysregulation in respiratory diseases: a review of current knowledge","volume":"15","author":"Song","year":"2024","journal-title":"Front. Physiol."},{"issue":"40","key":"10.1016\/j.prp.2026.156601_bib187","article-title":"CuO Nanozymes Catalyze Cysteine and Glutathione Depletion Induced Ferroptosis and Cuproptosis for Synergistic Tumor Therapy","volume":"20","author":"Bai","year":"2024","journal-title":"Small (Weinh. der Bergstr. Ger. )"},{"key":"10.1016\/j.prp.2026.156601_bib188","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1146\/annurev.nutr.21.1.193","article-title":"Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system [J","volume":"21","author":"Reddy","year":"2001","journal-title":"Annu. Rev. Nutr."},{"issue":"17","key":"10.1016\/j.prp.2026.156601_bib189","doi-asserted-by":"crossref","first-page":"15763","DOI":"10.1007\/s00432-023-05325-6","article-title":"Aberrant expression of cuproptosis\u2011related gene LIPT1 is associated with metabolic dysregulation of fatty acid and prognosis in hepatocellular carcinoma","volume":"149","author":"Li","year":"2023","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"3-4","key":"10.1016\/j.prp.2026.156601_bib190","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s10495-023-01928-z","article-title":"Ferroptosis and cuproptposis in kidney Diseases: dysfunction of cell metabolism","volume":"29","author":"Chen","year":"2024","journal-title":"Apoptosis international journal programmed cell death"},{"key":"10.1016\/j.prp.2026.156601_bib191","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.aquatox.2018.09.011","article-title":"A lipidomic approach to understand copper resilience in oyster Crassostrea hongkongensis","volume":"204","author":"Chan","year":"2018","journal-title":"Aquatic toxicology (Amsterdam Netherlands)"},{"key":"10.1016\/j.prp.2026.156601_bib192","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.173603","article-title":"Mitochondria UPR stimulation by pelargonidin-3-glucoside contributes to ameliorating lipid accumulation under copper exposure","volume":"942","author":"Han","year":"2024","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.prp.2026.156601_bib193","article-title":"Optogenetic and chemogenetic approaches for modeling neurological disorders in vivo","volume":"235","author":"G","year":"2024","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.prp.2026.156601_bib194","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2021.108883","article-title":"Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2\/PPAR\u03b3 pathways","volume":"100","author":"Zhong","year":"2022","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.prp.2026.156601_bib195","article-title":"Mechanisms and therapeutic strategies of copper homeostasis in the pathogenesis of sepsis-induced cardiomyopathy","volume":"14","author":"Xie","year":"2026","journal-title":"Front. Cell. Dev. Biol."},{"key":"10.1016\/j.prp.2026.156601_bib196","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.117783","article-title":"Copper excess induces autophagy dysfunction and mitochondrial ROS-ferroptosis progression, inhibits cellular biosynthesis of milk protein and lipid in bovine mammary epithelial cells","volume":"291","author":"Fan","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.prp.2026.156601_bib197","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112574","article-title":"Identification of diagnostic signature and immune infiltration for ischemic cardiomyopathy based on cuproptosis-related genes through bioinformatics analysis and experimental validation","volume":"138","author":"Tan","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.prp.2026.156601_bib198","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.892322","article-title":"Transcriptome and morphological analysis on the heart in gestational protein-restricted aging male rat offspring","volume":"10","author":"Folguieri","year":"2022","journal-title":"Front. Cell. Dev. Biol."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib199","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1084\/jem.20181892","article-title":"Cell death-mediated cytokine release and its therapeutic implications","volume":"216","author":"Place","year":"2019","journal-title":"J. Exp. Med."},{"issue":"17","key":"10.1016\/j.prp.2026.156601_bib200","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22179477","article-title":"Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)","volume":"22","author":"Pietrofesa","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.prp.2026.156601_bib201","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.1111\/dom.15946","article-title":"Associations between cuprotosis-related genes and the spectrum of metabolic dysfunction-associated fatty liver disease: An exploratory study","volume":"26","author":"Yuan","year":"2024","journal-title":"Diabetes Obes. & Metab."},{"key":"10.1016\/j.prp.2026.156601_bib202","doi-asserted-by":"crossref","DOI":"10.3724\/abbs.2025089","article-title":"LPS mediates cuproptosis and inflammation in THP-1 macrophages through HKDC1","author":"Ou","year":"2025","journal-title":"Acta Biochim. Et. Biophys. Sin."},{"key":"10.1016\/j.prp.2026.156601_bib203","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.996307","article-title":"HMGB1 is a mediator of cuproptosis-related sterile inflammation","volume":"10","author":"Liu","year":"2022","journal-title":"Front. Cell. Dev. Biol."},{"issue":"9","key":"10.1016\/j.prp.2026.156601_bib204","doi-asserted-by":"crossref","DOI":"10.1111\/cns.70039","article-title":"Cuproptosis: Mechanisms, biological significance, and advances in disease treatment-A systematic review","volume":"30","author":"Pan","year":"2024","journal-title":"CNS Neurosci. & Ther."},{"key":"10.1016\/j.prp.2026.156601_bib205","article-title":"Inflammatory immunity and bacteriological perspectives: A new direction for copper treatment of sepsis","volume":"84","author":"Huang","year":"2024","journal-title":"J. Trace Elem. Med. Biol. Organ. Soc. Miner. Trace Elem. (GMS"},{"key":"10.1016\/j.prp.2026.156601_bib206","article-title":"The emerging role of cuproptosis in spinal cord injury","volume":"16","author":"Xu","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.prp.2026.156601_bib207","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2025.114954","article-title":"Bimetallic nanozyme-mediated dual ferroptosis\/cuproptosis synergy potentiates immunotherapy in bladder cancer","volume":"255","author":"Chen","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.prp.2026.156601_bib208","article-title":"Cuproptosis: emerging biomarkers and potential therapeutics in cancers","volume":"13","author":"Wang","year":"2023","journal-title":"Front. Oncol."},{"key":"10.1016\/j.prp.2026.156601_bib209","article-title":"From copper homeostasis to cuproptosis: a new perspective on CNS immune regulation and neurodegenerative diseases","volume":"16","author":"Li","year":"2025","journal-title":"Front. Neurol."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib210","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1177\/00220345251313797","article-title":"Cuproptosis Aggravates Pulpitis by Inhibiting the Pentose Phosphate Pathway","volume":"104","author":"Zhou","year":"2025","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.prp.2026.156601_bib211","article-title":"Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set","volume":"12","author":"Liu","year":"2022","journal-title":"Front. Oncol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib212","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41598-024-84916-w","article-title":"Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy","volume":"15","author":"Li","year":"2025","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib213","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1093\/cvr\/cvx012","article-title":"Inflammation and metabolic cardiomyopathy","volume":"113","author":"Nishida","year":"2017","journal-title":"Cardiovasc. Res."},{"issue":"4","key":"10.1016\/j.prp.2026.156601_bib214","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.18632\/aging.205545","article-title":"Investigation of cuproptosis regulator-mediated modification patterns and SLC30A7 function in GBM","volume":"16","author":"Yu","year":"2024","journal-title":"Aging"},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib215","article-title":"Spermidine alleviates copper-induced oxidative stress, inflammation and cuproptosis in the liver","volume":"39","author":"Wang","year":"2025","journal-title":"FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol."},{"key":"10.1016\/j.prp.2026.156601_bib216","first-page":"880","article-title":"The role of redox-active iron, copper, manganese, and redox-inactive zinc in toxicity, oxidative stress, and human diseases","volume":"24","author":"Jomova","year":"2025","journal-title":"J. ]. Excli J."},{"issue":"D","key":"10.1016\/j.prp.2026.156601_bib217","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/eurheartj\/13.suppl_D.24","article-title":"Myocardial collagen matrix remodelling in arterial hypertension","volume":"13","author":"Brilla","year":"1992","journal-title":"Eur. Heart J."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib218","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1524-6175.2007.06626.x","article-title":"Mechanisms of cardiac fibrosis in hypertension","volume":"9","author":"D\u00edez","year":"2007","journal-title":"J. Clin. Hypertens. (Greenwich Conn. )"},{"key":"10.1016\/j.prp.2026.156601_bib219","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2025.1570131","article-title":"Cuproptosis and its potential role in musculoskeletal disease","volume":"13","author":"Xiang","year":"2025","journal-title":"Front. Cell. Dev. Biol."},{"key":"10.1016\/j.prp.2026.156601_bib220","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1039510","article-title":"Appropriate level of cuproptosis may be involved in alleviating pulmonary fibrosis","volume":"13","author":"Li","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.prp.2026.156601_bib221","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114141","article-title":"Aprocitentan mitigates doxorubicin-induced cardiotoxicity by inhibiting cuproptosis, oxidative stress, and mitochondrial impairments via the activation of sirtuin 7","volume":"148","author":"Chen","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"21-22","key":"10.1016\/j.prp.2026.156601_bib222","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1089\/hum.2020.004","article-title":"Sustained Oligomycin Sensitivity Conferring Protein Expression in Cardiomyocytes Protects Against Cardiac hypertrophy Induced by Pressure Overload via Improving Mitochondrial Function","volume":"31","author":"Guo","year":"2020","journal-title":"Hum. Gene Ther."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib223","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/s41423-026-01387-x","article-title":"Tackling cuproptosis: from metabolic rewiring to therapeutic exploitation in cancer","volume":"23","author":"Hao","year":"2026","journal-title":"Cell. Mol. Immunol."},{"issue":"12","key":"10.1016\/j.prp.2026.156601_bib224","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1161\/CIRCRESAHA.119.316311","article-title":"Myofilament Phosphorylation in Stem Cell Treated Diastolic Heart Failure","volume":"129","author":"Soetkamp","year":"2021","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib225","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s12933-025-02623-w","article-title":"Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling","volume":"24","author":"Grootaert","year":"2025","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.prp.2026.156601_bib226","doi-asserted-by":"crossref","DOI":"10.1016\/j.mvr.2021.104300","article-title":"Microvascular rarefaction in patients with cerebrovascular events","volume":"140","author":"Wadowski","year":"2022","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.prp.2026.156601_bib227","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.biopha.2017.08.138","article-title":"Bamboo leaf extract ameliorates cardiac fibrosis possibly via alleviating inflammation, oxidative stress and apoptosis","volume":"95","author":"Zhang","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib228","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1007\/s11357-022-00565-9","article-title":"Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis","volume":"44","author":"Rajesh","year":"2022","journal-title":"GeroScience"},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib229","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/s41419-023-05639-w","article-title":"Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies","volume":"14","author":"Chen","year":"2023","journal-title":"Cell. Death Dis."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib230","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16030647","article-title":"Cuproptosis: Unraveling the Mechanisms of Copper-Induced Cell Death and Its Implication in Cancer Therapy","volume":"16","author":"Springer","year":"2024","journal-title":"Cancers (Basel)"},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib231","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25115890","article-title":"Copper Chelation Therapy Attenuates Periodontitis Inflammation through the Cuproptosis\/Autophagy\/Lysosome Axis","volume":"25","author":"Zhang","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib232","first-page":"639","article-title":"D-penicillamine-associated neutropenia in a Doberman pinscher","volume":"64","author":"Brooks","year":"2023","journal-title":"Can. Vet. J. = La Rev. Vet. Can."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib233","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202101164","article-title":"Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage","volume":"5","author":"Borchard","year":"2022","journal-title":"Life Sci. Alliance"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib234","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/s12935-025-03864-1","article-title":"Cuproptosis: a novel therapeutic mechanism in lung cancer","volume":"25","author":"Luo","year":"2025","journal-title":"Cancer Cell. Int."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib235","doi-asserted-by":"crossref","first-page":"R123","DOI":"10.1530\/JOE-16-0594","article-title":"STEAP4: its emerging role in metabolism and homeostasis of cellular iron and copper","volume":"234","author":"Scarl","year":"2017","journal-title":"J. Endocrinol."},{"issue":"6","key":"10.1016\/j.prp.2026.156601_bib236","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s10534-015-9886-0","article-title":"Core domain mutant Y220C of p53 protein has a key role in copper homeostasis in case of free fatty acids overload","volume":"28","author":"Arciello","year":"2015","journal-title":"Biometals international journal role metal ions biology biochemistry medicine"},{"key":"10.1016\/j.prp.2026.156601_bib237","doi-asserted-by":"crossref","DOI":"10.17305\/bb.2025.12751","article-title":"Tumor glucose reprogramming suppresses cuproptosis: A review","author":"Song","year":"2025","journal-title":"Biomol. & Biomed."},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib238","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpet.2024.100048","article-title":"Elesclomol rescues mitochondrial copper deficiency in disease models without triggering cuproptosis","volume":"392","author":"Zulkifli","year":"2025","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib239","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/s12951-025-03284-3","article-title":"Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation","volume":"23","author":"Gu","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.prp.2026.156601_bib240","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123523","article-title":"Disrupting intracellular redox homeostasis through copper-driven dual cell death to induce anti-tumor immunotherapy","volume":"324","author":"Wang","year":"2026","journal-title":"Biomaterials"},{"key":"10.1016\/j.prp.2026.156601_bib241","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.actbio.2023.12.022","article-title":"Copper-coordinated nanoassemblies based on photosensitizer-chemo prodrugs and checkpoint inhibitors for enhanced apoptosis-cuproptosis and immunotherapy","volume":"175","author":"Liang","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.prp.2026.156601_bib242","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123626","article-title":"A metallic metabolic nano-regulator reprograms the PKM2\/HIF-1\u03b1\/DLAT axis to amplify tumor-specific cuproptosis","volume":"325","author":"Zhan","year":"2026","journal-title":"Biomaterials"},{"key":"10.1016\/j.prp.2026.156601_bib243","article-title":"Qihuang Zhuyu formula alleviates coronary microthrombosis by inhibiting PI3K\/Akt\/\u03b1IIb\u03b23-mediated platelet activation","volume":"125","author":"Ding","year":"2024"},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib244","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2217\/fca-2017-0019","article-title":"PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part II: PPAR-\u03b2\/\u03b4 and PPAR-\u03b3","volume":"13","author":"Han","year":"2017","journal-title":"J. Future Cardiol."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib245","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.2174\/1381612823666161118145850","article-title":"Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Agonists as Therapeutic Agents for Cardiovascular Disorders: Focus on Atherosclerosis","volume":"23","author":"Ivanova","year":"2017","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib246","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1186\/s12916-022-02635-3","article-title":"Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease","volume":"20","author":"Karlson","year":"2022","journal-title":"BMC Med."},{"key":"10.1016\/j.prp.2026.156601_bib247","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101706","article-title":"Short-chain fatty acid metabolism and multiple effects on cardiovascular diseases","volume":"81","author":"Hu","year":"2022","journal-title":"Ageing Res. Rev."},{"issue":"11","key":"10.1016\/j.prp.2026.156601_bib248","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1161\/CIRCULATIONAHA.118.036652","article-title":"Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage","volume":"139","author":"Bartolomaeus","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.prp.2026.156601_bib249","article-title":"The signaling pathways of selected traditional Chinese medicine prescriptions and their metabolites in the treatment of diabetic cardiomyopathy: a review","volume":"15","author":"Li","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.prp.2026.156601_bib250","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107841","article-title":"Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1\/NF-\u03baB pathway","volume":"98","author":"Ren","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib251","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-67362-2","article-title":"Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats","volume":"10","author":"Yan","year":"2020","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.prp.2026.156601_bib252","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1080\/14786419.2024.2319650","article-title":"Identifying potential Q-markers for quality evaluation of Zhenyuan capsule by integrating chemical analysis, network pharmacology, molecular docking, and molecular dynamics simulations","volume":"39","author":"Zhao","year":"2025","journal-title":"Nat. Prod. Res."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib253","doi-asserted-by":"crossref","DOI":"10.1155\/bmri\/9932683","article-title":"Exploring the Mechanism of Shexiang Baoxin Pill in the Treatment of Ischemic Stroke: A Study Integrating Network Pharmacology, Machine Learning, Molecular Docking, and Molecular Dynamics Simulation","volume":"2026","author":"Fu","year":"2026","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.prp.2026.156601_bib254","doi-asserted-by":"crossref","DOI":"10.2174\/0113816128393399251021101651","article-title":"Integrative Approaches to Uncover the Therapeutic Action of Huaiqihuang in Myocarditis: Network Pharmacology, Molecular Docking, and Molecular Dynamics","author":"Du","year":"2026","journal-title":"Curr. Pharm. Des."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib255","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27030672","article-title":"The Biodiversity of the Genus Dictyota: Phytochemical and Pharmacological Natural Products Prospectives","volume":"27","author":"Rushdi","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.prp.2026.156601_bib256","article-title":"Impact of extraction techniques on phytochemical composition and bioactivity of natural product mixtures","volume":"16","author":"Sun","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.prp.2026.156601_bib257","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.1013013","article-title":"Edgeworthia gardneri (Wall.) Meisn. extract protects against myocardial infarction by inhibiting NF-\u03baB-and MAPK-mediated endothelial inflammation","volume":"9","author":"Wei","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.prp.2026.156601_bib258","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.754254","article-title":"Extracellular Vesicles Derived From Regeneration Associated Cells Preserve Heart Function After Ischemia-Induced Injury","volume":"8","author":"Salybekov","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"issue":"3","key":"10.1016\/j.prp.2026.156601_bib259","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1189\/jlb.72.3.503","article-title":"Interleukin-10 inhibits proinflammatory activation of endothelium in response to Borrelia burgdorferi or lipopolysaccharide but not interleukin-1beta or tumor necrosis factor alpha [J","volume":"72","author":"Lisinski","year":"2002","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.prp.2026.156601_bib260","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/7532892","article-title":"YQWY Decoction Improves Myocardial Remodeling via Activating the IL-10\/Stat3 Signaling Pathway","volume":"2020","author":"Li","year":"2020","journal-title":"Evid. -Based Complement. Altern. Med. eCAM"},{"issue":"2","key":"10.1016\/j.prp.2026.156601_bib261","first-page":"123","article-title":"Punicalagin attenuates isoproterenol-induced myocardial infarction through nuclear factor erythroid 2-related factor 2\/silent information regulator transcript-1-mediated inhibition of inflammation and cardiac stress markers in experimental animal models","volume":"75","author":"Liao","year":"2024","journal-title":"J. Physiol. Pharmacol. Off. J. Pol. Physiol. Soc."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib262","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1186\/s12916-025-04203-x","article-title":"Lactobacillus ameliorates myocardial ischemia reperfusion injury by attenuating apoptosis, inflammation, oxidative stress, and ferroptosis","volume":"23","author":"Liang","year":"2025","journal-title":"BMC Med."},{"key":"10.1016\/j.prp.2026.156601_bib263","first-page":"623","article-title":"A self-locking conductive cardiac patch for immediate electrical integration with infarcted rat myocardium","volume":"56","author":"Shan","year":"2026","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.prp.2026.156601_bib264","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122805","article-title":"Harnessing nanomaterials for copper-induced cell death","volume":"313","author":"Li","year":"2025","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib265","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41420-023-01796-1","article-title":"Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies","volume":"10","author":"Yang","year":"2024","journal-title":"Cell. Death Discov."},{"issue":"1","key":"10.1016\/j.prp.2026.156601_bib266","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/s12951-024-02410-x","article-title":"Hyaluronic acid stimulation of stem cells for cardiac repair: a cell-free strategy for myocardial infarct","volume":"22","author":"Jeong","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"7","key":"10.1016\/j.prp.2026.156601_bib267","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1038\/s41440-023-01305-y","article-title":"Celiac ganglia neurolysis suppresses high blood pressure in rats","volume":"46","author":"Dai","year":"2023","journal-title":"Hypertens. Res."},{"issue":"5","key":"10.1016\/j.prp.2026.156601_bib268","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2024.13334","article-title":"Copper ions: The invisible killer of cardiovascular disease (Review)","volume":"30","author":"Wang","year":"2024","journal-title":"Mol. Med. Rep."},{"issue":"18","key":"10.1016\/j.prp.2026.156601_bib269","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202309984","article-title":"Elesclomol Loaded Copper Oxide Nanoplatform Triggers Cuproptosis to Enhance Antitumor Immunotherapy","volume":"11","author":"Lu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.prp.2026.156601_bib270","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.2147\/JIR.S502203","article-title":"Identification of Necroptosis and Immune Infiltration in Heart Failure Through Bioinformatics Analysis","volume":"18","author":"Zhu","year":"2025","journal-title":"J. Inflamm. Res."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033826002542?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033826002542?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T02:37:24Z","timestamp":1786502244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033826002542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":270,"alternative-id":["S0344033826002542"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2026.156601","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cuproptosis-mediated metabolic\u2013inflammatory coupling in hypertensive myocardial injury: Mechanistic insights and therapeutic perspectives","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2026.156601","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"156601"}}