{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:27:03Z","timestamp":1786505223359,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology - Research and Practice"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.prp.2026.156628","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:07:11Z","timestamp":1784732831000},"page":"156628","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Regulation of FN1 levels in endometrial cancer cells: Probiotics activate the p62-dependent autophagy-lysosome pathway to reduce tumor metastasis"],"prefix":"10.1016","volume":"286","author":[{"given":"Shuqi","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianchao","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10333","key":"10.1016\/j.prp.2026.156628_bib1","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/S0140-6736(22)00323-3","article-title":"Endometrial cancer","volume":"399","author":"Crosbie","year":"2022","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.prp.2026.156628_bib2","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1158\/2159-8290.CD-24-1451","article-title":"Cancer in 2024","volume":"14","author":"AACR Cancer Disparities Progress Report 2024 Steering Committee","year":"2024","journal-title":"Cancer Discov."},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib3","first-page":"10","article-title":"Cancer statistics, 2025","volume":"75","author":"Siegel","year":"2025","journal-title":"CA Cancer J Clin"},{"issue":"11","key":"10.1016\/j.prp.2026.156628_bib4","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.3390\/cancers16112027","article-title":"Landscape of Endometrial Cancer: Molecular Mechanisms, Biomarkers, and Target Therapy","volume":"16","author":"Bostan","year":"2024","journal-title":"Cancers"},{"issue":"10","key":"10.1016\/j.prp.2026.156628_bib5","doi-asserted-by":"crossref","first-page":"5756","DOI":"10.3390\/ijms23105756","article-title":"The Role of Microbiota in the Immunopathogenesis of Endometrial Cancer","volume":"23","author":"Sobstyl","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.prp.2026.156628_bib6","doi-asserted-by":"crossref","DOI":"10.4014\/jmb.2503.03048","article-title":"Distinct Microbial Signatures along the Female Reproductive Tract in Endometrial Cancer Patients","volume":"35","author":"Xu","year":"2025","journal-title":"J. Microbiol. Biotechnol."},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib7","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1007\/s12672-025-03296-3","article-title":"Gut microbiota and urological cancers: from microecological imbalance to potential for precision therapy","volume":"16","author":"Cui","year":"2025","journal-title":"Discov. Onc"},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib8","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/s42003-025-08261-y","article-title":"Human placenta mesenchymal stromal cells alleviate intestinal inflammation and repair intestinal barrier function by activating AMPK-FXR pathway","volume":"8","author":"Wang","year":"2025","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib9","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s12866-025-03767-1","article-title":"Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment","volume":"25","author":"Zhang","year":"2025","journal-title":"BMC Microbiol."},{"issue":"7402","key":"10.1016\/j.prp.2026.156628_bib10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature11234","article-title":"Structure, function and diversity of the healthy human microbiome","volume":"486","author":"The Human Microbiome Project Consortium","year":"2012","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.prp.2026.156628_bib11","doi-asserted-by":"crossref","first-page":"R81","DOI":"10.1530\/REP-21-0120","article-title":"Current findings in endometrial microbiome: impact on uterine diseases","volume":"163","author":"Medina-Bastidas","year":"2022","journal-title":"Reprod. (Camb. Engl. )"},{"key":"10.1016\/j.prp.2026.156628_bib12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.maturitas.2017.06.025","article-title":"Estrogen-gut microbiome axis: Physiological and clinical implications","volume":"103","author":"Baker","year":"2017","journal-title":"Maturitas"},{"key":"10.1016\/j.prp.2026.156628_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1328620","article-title":"Therapeutic potential of popular fermented dairy products and its benefits on human health","volume":"11","author":"Saleem","year":"2024","journal-title":"Front. Nutr."},{"issue":"6","key":"10.1016\/j.prp.2026.156628_bib14","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.cmet.2023.04.015","article-title":"Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8(+) T cell immunity","volume":"35","author":"Zhang","year":"2023","journal-title":"Cell. Metab."},{"key":"10.1016\/j.prp.2026.156628_bib15","article-title":"Assessment of Probiotic and Prebiotic Use in Gynecologic Cancer Patients: A Systematic Review","author":"Chalif","year":"2025","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s13062-024-00481-2","article-title":"YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1\/PI3K\/AKT pathway","volume":"19","author":"Lin","year":"2024","journal-title":"Biol. Direct"},{"issue":"27","key":"10.1016\/j.prp.2026.156628_bib17","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1038\/s41388-020-1348-7","article-title":"GBP2 enhances glioblastoma invasion through Stat3\/fibronectin pathway","volume":"39","author":"Yu","year":"2020","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3390\/cells9010149","article-title":"Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer","volume":"9","author":"Kujawa","year":"2020","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib19","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41368-020-00101-5","article-title":"Regulation of FN1 degradation by the p62\/SQSTM1-dependent autophagy-lysosome pathway in HNSCC","volume":"12","author":"Liu","year":"2020","journal-title":"Int. J. Oral. Sci."},{"issue":"3","key":"10.1016\/j.prp.2026.156628_bib20","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1021\/acs.biochem.2c00252","article-title":"p62 Phase-Separation as the Foundation of Autophagy-Based Degraders","volume":"62","author":"Takahashi","year":"2023","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.prp.2026.156628_bib21","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1186\/s12967-024-04946-w","article-title":"Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction","volume":"22","author":"Feng","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.prp.2026.156628_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.839416","article-title":"The Two-Faced Role of Autophagy in Endometrial Cancer","volume":"10","author":"Fukuda","year":"2022","journal-title":"Front. Cell. Dev. Biol."},{"issue":"4","key":"10.1016\/j.prp.2026.156628_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2024.107206","article-title":"Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression","volume":"300","author":"Lee","year":"2024","journal-title":"J. Biol. Chem."},{"issue":"20","key":"10.1016\/j.prp.2026.156628_bib24","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202501383RR","article-title":"METTL3 Affects Endometrial Receptivity Through Modulation of P62-Mediated Autophagic Flux","volume":"39","author":"Zhang","year":"2025","journal-title":"FASEB J."},{"issue":"6","key":"10.1016\/j.prp.2026.156628_bib25","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/s41577-023-00882-w","article-title":"Probiotics promote local antitumour immunity","volume":"23","author":"Bird","year":"2023","journal-title":"Nat. Rev. Immunol."}],"container-title":["Pathology - Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033826002815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0344033826002815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T02:31:26Z","timestamp":1786501886000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0344033826002815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":25,"alternative-id":["S0344033826002815"],"URL":"https:\/\/doi.org\/10.1016\/j.prp.2026.156628","relation":{},"ISSN":["0344-0338"],"issn-type":[{"value":"0344-0338","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regulation of FN1 levels in endometrial cancer cells: Probiotics activate the p62-dependent autophagy-lysosome pathway to reduce tumor metastasis","name":"articletitle","label":"Article Title"},{"value":"Pathology - Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prp.2026.156628","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"156628"}}