{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:46:13Z","timestamp":1786995973036,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["practicalradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Radiation Oncology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.prro.2017.01.005","type":"journal-article","created":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T13:17:04Z","timestamp":1483795024000},"page":"e299-e308","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of reduction mammoplasty on acute radiation side effects and use of lumpectomy cavity boosts"],"prefix":"10.1016","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5660-6365","authenticated-orcid":false,"given":"Jolinta Y.","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Bluebond-Langner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enid","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Cheston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth M.","family":"Nichols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randi J.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soren M.","family":"Bentzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Drogula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Kesmodel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Bellavance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Rosenblatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Tkaczuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheri","family":"Slezak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Feigenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prro.2017.01.005_bb0005","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1200\/JCO.1996.14.5.1558","article-title":"Conservative treatment versus mastectomy in early breast cancer: Patterns of failure with 15 years of follow-up data. Institut Gustave-Roussy Breast Cancer Group","volume":"14","author":"Arriagada","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0010","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1080\/02841860801971439","article-title":"Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol","volume":"47","author":"Blichert-Toft","year":"2008","journal-title":"Acta Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0015","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1056\/NEJMoa022152","article-title":"Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer","volume":"347","author":"Fisher","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2017.01.005_bb0020","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1002\/cncr.11580","article-title":"Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: The National Cancer Institute Randomized Trial","volume":"98","author":"Poggi","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.prro.2017.01.005_bb0025","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/jnci\/92.14.1143","article-title":"Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organisation for Research and Treatment of Cancer 10801 trial","volume":"92","author":"van Dongen","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.prro.2017.01.005_bb0030","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1056\/NEJMoa020989","article-title":"Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer","volume":"347","author":"Veronesi","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2017.01.005_bb0035","doi-asserted-by":"crossref","first-page":"djv263","DOI":"10.1093\/jnci\/djv263","article-title":"Trends in treatment patterns and outcomes for ductal carcinoma in situ","volume":"107","author":"Worni","year":"2015","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.prro.2017.01.005_bb0040","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/0167-8140(94)90063-9","article-title":"The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity","volume":"33","author":"Moody","year":"1994","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0045","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0360-3016(91)90781-X","article-title":"Primary breast irradiation in large-breasted or heavy women: Analysis of cosmetic outcome","volume":"21","author":"Gray","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0050","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/0360-3016(94)00480-3","article-title":"Factors influencing cosmetic results after conservation therapy for breast cancer","volume":"31","author":"Taylor","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0055","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.radonc.2009.03.003","article-title":"A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: Baseline characteristics and dosimetry results","volume":"92","author":"Barnett","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0060","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1200\/JCO.2007.15.2488","article-title":"A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis","volume":"26","author":"Pignol","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0065","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.ijrobp.2011.08.020","article-title":"Prone whole-breast irradiation using three-dimensional conformal radiotherapy in women undergoing breast conservation for early disease yields high rates of excellent to good cosmetic outcomes in patients with large and\/or pendulous breasts","volume":"83","author":"Bergom","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5306\/wjco.v5.i1.1","article-title":"Current aspects of therapeutic reduction mammaplasty for immediate early breast cancer management: An update","volume":"5","author":"Munhoz","year":"2014","journal-title":"World J Clin Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0075","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.amjsurg.2004.01.002","article-title":"Bilateral reduction mammoplasty in combination with lumpectomy for treatment of breast cancer in patients with macromastia","volume":"187","author":"Chang","year":"2004","journal-title":"Am J Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0080","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0002-9610(01)00563-3","article-title":"Reduction mammoplasty improves breast conservation therapy in patients with macromastia","volume":"181","author":"Newman","year":"2001","journal-title":"Am J Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0085","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S1470-2045(14)71156-8","article-title":"Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20-year follow-up of a randomised phase 3 trial","volume":"16","author":"Bartelink","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0090","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1200\/JCO.1997.15.3.963","article-title":"Role of a 10-Gy boost in the conservative treatment of early breast cancer: Results of a randomized clinical trial in Lyon, France","volume":"15","author":"Romestaing","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0095","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.ijrobp.2006.11.026","article-title":"Variability among breast radiation oncologists in delineation of the postsurgical lumpectomy cavity","volume":"67","author":"Landis","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0100","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1002\/cncr.11142","article-title":"Breast boost: Are we missing the target?","volume":"97","author":"Benda","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.prro.2017.01.005_bb0105","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/0360-3016(95)02258-9","article-title":"Does the placement of surgical clips within the excision cavity influence local control for patients treated with breast-conserving surgery and irradiation","volume":"34","author":"Fein","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0110","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijrobp.2005.01.044","article-title":"Definition of postlumpectomy tumor bed for radiotherapy boost field planning: CT versus surgical clips","volume":"63","author":"Goldberg","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0115","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ijrobp.2010.04.067","article-title":"Impact of the radiation boost on outcomes after breast-conserving surgery and radiation","volume":"81","author":"Murphy","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2017.01.005_bb0120","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1055\/s-2004-831912","article-title":"Reduction mammaplasty in conjunction with breast conservation","volume":"18","author":"Spear","year":"2004","journal-title":"Semin Plast Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0125","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jamcollsurg.2007.12.052","article-title":"Autologous breast reconstruction: The Vanderbilt experience (1998 to 2005) of independent predictors of displeasing outcomes","volume":"207","author":"Greco","year":"2008","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0130","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1097\/01.prs.0000252003.14537.d2","article-title":"Effect of obesity on flap and donor-site complications in pedicled tram flap breast reconstruction","volume":"119","author":"Spear","year":"2007","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0135","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1245\/ASO.2005.12.046","article-title":"Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer","volume":"12","author":"Kaur","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0140","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.ejso.2007.09.012","article-title":"Outcomes of bilateral mammoplasty for early stage breast cancer","volume":"34","author":"Caruso","year":"2008","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0145","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1245\/s10434-013-3235-8","article-title":"Local recurrence patterns in breast cancer patients treated with oncoplastic reduction mammaplasty and radiotherapy","volume":"21","author":"Eaton","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0150","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/00000637-199809000-00002","article-title":"Reduction mammaplasty: Its role in breast conservation surgery for early-stage breast cancer","volume":"41","author":"Smith","year":"1998","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.prro.2017.01.005_bb0155","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.breast.2007.01.008","article-title":"Long-term oncological results of breast conservative treatment with oncoplastic surgery","volume":"16","author":"Rietjens","year":"2007","journal-title":"Breast"},{"key":"10.1016\/j.prro.2017.01.005_bb0160","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.prro.2014.04.002","article-title":"Radiation practice patterns among United States radiation oncologists for postmastectomy breast reconstruction and oncoplastic breast reduction","volume":"4","author":"Thomas","year":"2014","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0165","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.semradonc.2011.09.007","article-title":"Quality indicators for breast cancer: Revisiting historical evidence in the context of technology changes","volume":"22","author":"Poortmans","year":"2012","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0170","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/jnci\/94.15.1143","article-title":"Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer","volume":"94","author":"Whelan","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.prro.2017.01.005_bb0175","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S1470-2045(08)70077-9","article-title":"The UK standardisation of breast radiotherapy (START) trial A of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial","volume":"9","author":"START Trialists\u2019 Group","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.prro.2017.01.005_bb0180","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/S0140-6736(08)60348-7","article-title":"The UK standardisation of breast radiotherapy (START) trial B of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial","volume":"371","author":"START Trialists\u2019 Group","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.prro.2017.01.005_bb0185","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/S1470-2045(13)70386-3","article-title":"The UK standardisation of breast radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials","volume":"14","author":"Haviland","year":"2013","journal-title":"Lancet Oncol"}],"container-title":["Practical Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187985001730005X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187985001730005X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:20:21Z","timestamp":1761819621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S187985001730005X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S187985001730005X"],"URL":"https:\/\/doi.org\/10.1016\/j.prro.2017.01.005","relation":{},"ISSN":["1879-8500"],"issn-type":[{"value":"1879-8500","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of reduction mammoplasty on acute radiation side effects and use of lumpectomy cavity boosts","name":"articletitle","label":"Article Title"},{"value":"Practical Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prro.2017.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}