{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:33:00Z","timestamp":1790519580434,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["practicalradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Radiation Oncology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.prro.2018.02.001","type":"journal-article","created":{"date-parts":[[2018,2,13]],"date-time":"2018-02-13T12:06:25Z","timestamp":1518523585000},"page":"e285-e294","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Assessing the utility of the spinal instability neoplastic score (SINS) to predict fracture after conventional radiation therapy (RT) for spinal metastases"],"prefix":"10.1016","volume":"8","author":[{"given":"Diana D.","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren M.","family":"Hertan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai Chung","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Skamene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Chi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Groff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles H.","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco L.","family":"Ferrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchel","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy A.","family":"Balboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prro.2018.02.001_bb0005","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0140-6736(05)66954-1","article-title":"Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: A randomised trial","volume":"366","author":"Patchell","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.prro.2018.02.001_bb0010","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.ijrobp.2006.06.021","article-title":"Cost-effectiveness of surgery plus radiotherapy versus radiotherapy alone for metastatic epidural spinal cord compression","volume":"66","author":"Thomas","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2018.02.001_bb0015","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1056\/NEJM199208273270907","article-title":"Spinal cord compression from epidural metastases","volume":"327","author":"Byrne","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2018.02.001_bb0020","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3171\/jns.1985.63.5.0676","article-title":"Treatment of neoplastic epidural cord compression by vertebral body resection and stabilization","volume":"63","author":"Sundaresan","year":"1985","journal-title":"J Neurosurg"},{"key":"10.1016\/j.prro.2018.02.001_bb0025","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1200\/JCO.1995.13.9.2330","article-title":"Surgical treatment of spinal cord compression from epidural metastasis","volume":"13","author":"Sundaresan","year":"1995","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0885-3924(93)90113-A","article-title":"The management of spinal cord compression in patients with advanced malignancy","volume":"8","author":"Ingham","year":"1993","journal-title":"J Pain Symptom Manag"},{"key":"10.1016\/j.prro.2018.02.001_bb0035","first-page":"5","article-title":"Instability and impending instability of the thoracolumbar spine in patients with spinal metastases: A systematic review","volume":"38","author":"Weber","year":"2011","journal-title":"Int J Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0040","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00003086-198410000-00008","article-title":"Spinal instability as defined by the three-column spine concept in acute spinal trauma","author":"Denis","year":"1984","journal-title":"Clin Orthop"},{"key":"10.1016\/j.prro.2018.02.001_bb0045","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.spinee.2009.04.003","article-title":"The evolution of thoracolumbar injury classification systems","volume":"9","author":"Sethi","year":"2009","journal-title":"Spine J"},{"key":"10.1016\/j.prro.2018.02.001_bb0050","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1148\/rg.337135018","article-title":"Traumatic thoracolumbar spine injuries: What the spine surgeon wants to know","volume":"33","author":"Khurana","year":"2013","journal-title":"RadioGraphics"},{"key":"10.1016\/j.prro.2018.02.001_bb0055","doi-asserted-by":"crossref","first-page":"461","DOI":"10.2106\/00004623-198365040-00006","article-title":"The value of computed tomography in thoracolumbar fractures. An analysis of one hundred consecutive cases and a new classification","volume":"65","author":"McAfee","year":"1983","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.prro.2018.02.001_bb0060","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00003086-198912000-00027","article-title":"Metastatic disease in long bones. A proposed scoring system for diagnosing impending pathologic fractures","author":"Mirels","year":"1989","journal-title":"Clin Orthop"},{"key":"10.1016\/j.prro.2018.02.001_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/foc.2003.14.1.9","article-title":"Spinal instability and deformity due to neoplastic conditions","volume":"14","author":"Fourney","year":"2003","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.prro.2018.02.001_bb0070","doi-asserted-by":"crossref","first-page":"E1221","DOI":"10.1097\/BRS.0b013e3181e16ae2","article-title":"A novel classification system for spinal instability in neoplastic disease: An evidence-based approach and expert consensus from the Spine Oncology Study Group","volume":"35","author":"Fisher","year":"2010","journal-title":"Spine"},{"key":"10.1016\/j.prro.2018.02.001_bb0075","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1200\/JCO.2010.34.3897","article-title":"Spinal instability neoplastic score: an analysis of reliability and validity from the spine oncology study group","volume":"29","author":"Fourney","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0080","doi-asserted-by":"crossref","first-page":"869","DOI":"10.2214\/AJR.13.12269","article-title":"Reliability of the spinal instability neoplastic scale among radiologists: An assessment of instability secondary to spinal metastases","volume":"203","author":"Fisher","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.prro.2018.02.001_bb0085","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1748-717X-9-69","article-title":"Reliability of the spinal instability neoplastic score (SINS) among radiation oncologists: An assessment of instability secondary to spinal metastases","volume":"9","author":"Fisher","year":"2014","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0090","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.prro.2016.08.001","article-title":"Palliative radiation therapy for bone metastases: Update of an ASTRO Evidence-Based Guideline","volume":"7","author":"Lutz","year":"2017","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0095","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.prro.2018.02.001_bb0100","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s11060-015-1990-z","article-title":"Can the spinal instability neoplastic score prior to spinal radiosurgery predict compression fractures following stereotactic spinal radiosurgery for metastatic spinal tumor? A post hoc analysis of prospective phase II single-institution trials","volume":"126","author":"Lee","year":"2016","journal-title":"J Neuro-Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0105","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1200\/JCO.2013.50.1411","article-title":"Vertebral compression fracture after spine stereotactic body radiotherapy: A multi-institutional analysis with a focus on radiation dose and the spinal instability neoplastic score","volume":"31","author":"Sahgal","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2018.02.001_bb0110","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ijrobp.2016.09.029","article-title":"Volume of lytic vertebral body metastatic disease quantified using computed tomography\u2013based image segmentation predicts fracture risk after spine stereotactic body radiation therapy","volume":"97","author":"Thibault","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2018.02.001_bb0115","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.rpor.2014.04.009","article-title":"Radiation therapy for the management of painful bone metastases: Results from a randomized trial","volume":"19","author":"Guti\u00e9rrez Bayard","year":"2014","journal-title":"Rep Pract Oncol Radiother"},{"key":"10.1016\/j.prro.2018.02.001_bb0120","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ijrobp.2015.06.006","article-title":"Adverse outcomes after palliative radiation therapy for uncomplicated spine metastases: Role of spinal instability and single-fraction radiation therapy","volume":"93","author":"Lam","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2018.02.001_bb0125","unstructured":"Faruqi S, Tseng C-L, Whyne C, et al. Vertebral compression fracture after spine stereotactic body radiation therapy: A review of the pathophysiology and risk factors. Neurosurgery https:\/\/doi.org\/10.1093\/neuros\/nyx493, [e-pub ahead of print, accessed February 26, 2018]."}],"container-title":["Practical Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850018300523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850018300523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:21:18Z","timestamp":1761819678000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879850018300523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1879850018300523"],"URL":"https:\/\/doi.org\/10.1016\/j.prro.2018.02.001","relation":{},"ISSN":["1879-8500"],"issn-type":[{"value":"1879-8500","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessing the utility of the spinal instability neoplastic score (SINS) to predict fracture after conventional radiation therapy (RT) for spinal metastases","name":"articletitle","label":"Article Title"},{"value":"Practical Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prro.2018.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}]}}