{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T02:05:30Z","timestamp":1784167530590,"version":"3.55.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["practicalradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Radiation Oncology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.prro.2020.01.001","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T19:49:04Z","timestamp":1580500144000},"page":"330-338","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Prospective Trial to Compare Deep Inspiratory Breath Hold With Prone Breast Irradiation"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6061-0498","authenticated-orcid":false,"given":"Naamit K.","family":"Gerber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry X.","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Levinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen A.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indra J.","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier G.","family":"Maisonet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly","family":"Huppert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana K.","family":"No","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Kelley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Mistry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine J.","family":"Hitchen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3758-6976","authenticated-orcid":false,"given":"Judith D.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prro.2020.01.001_bib1","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.ijrobp.2015.11.040","article-title":"Cardiovascular disease risk in a large, population-based cohort of breast cancer survivors","volume":"94","author":"Boekel","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib2","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.ijrobp.2015.12.018","article-title":"Modern radiation therapy and cardiac outcomes in breast cancer","volume":"94","author":"Boero","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib3","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.ijrobp.2017.06.018","article-title":"Effect of breast irradiation on cardiac disease in women enrolled in BCIRG-001 at 10-year follow-up","volume":"99","author":"Wu","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib4","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa1209825","article-title":"Risk of ischemic heart disease in women after radiotherapy for breast cancer","volume":"368","author":"Darby","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2020.01.001_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.ijrobp.2010.12.058","article-title":"Changes in pulmonary function up to 10 years after locoregional breast irradiation","volume":"82","author":"Erven","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib6","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.ijrobp.2006.03.008","article-title":"Changes in pulmonary function after incidental lung irradiation for breast cancer: A prospective study","volume":"65","author":"Jaen","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib7","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0360-3016(91)90782-Y","article-title":"Radiation pneumonitis in breast cancer patients treated with conservative surgery and radiation therapy","volume":"21","author":"Lingos","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib8","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.radonc.2014.05.004","article-title":"Risk of second primary lung cancer in women after radiotherapy for breast cancer","volume":"111","author":"Grantzau","year":"2014","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib9","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/bjc.2012.575","article-title":"Radiation-related mortality\u00a0from heart disease and lung cancer more than 20 years after radiotherapy for breast cancer","volume":"108","author":"Henson","year":"2013","journal-title":"Br J Cancer"},{"key":"10.1016\/j.prro.2020.01.001_bib10","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1200\/JCO.2016.72.0722","article-title":"Estimating the risks of breast cancer radiotherapy: Evidence from modern radiation doses to the lungs and heart and from previous randomized trials","volume":"35","author":"Taylor","year":"2017","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib11","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.prro.2013.10.006","article-title":"Introduction of moderate deep inspiration breath hold for radiation therapy of left breast: Initial experience of a regional cancer center","volume":"4","author":"Comsa","year":"2014","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib12","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.radonc.2005.07.009","article-title":"Breathing adapted radiotherapy for breast cancer: comparison of free breathing gating with the breath-hold technique","volume":"76","author":"Korreman","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib13","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.radonc.2012.10.016","article-title":"Improved heart, lung and target dose with deep inspiration breath hold in a large clinical series of breast cancer patients","volume":"106","author":"Nissen","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.radonc.2004.03.012","article-title":"Breathing adapted radiotherapy of breast cancer: reduction of cardiac and pulmonary doses using voluntary inspiration breath-hold","volume":"72","author":"Pedersen","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0360-3016(00)01455-3","article-title":"Deep inspiration breath hold to reduce irradiated heart volume in breast cancer patients","volume":"49","author":"Sixel","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib16","doi-asserted-by":"crossref","first-page":"e579","DOI":"10.1016\/j.prro.2019.06.020","article-title":"Biological indices evaluation of various treatment techniques for left-sided breast treatment","volume":"9","author":"Saini","year":"2019","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/acm2.12382","article-title":"Evaluation of sparing organs at risk (OARs) in left-breast irradiation in the supine and prone positions and with deep inspiration breath-hold","volume":"19","author":"Saini","year":"2018","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib18","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1001\/2012.jama.10759","article-title":"Prone vs supine positioning for breast cancer radiotherapy","volume":"308","author":"Formenti","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.prro.2020.01.001_bib19","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.ijrobp.2014.03.036","article-title":"Prone breast intensity modulated radiation therapy: 5-year results","volume":"89","author":"Osa","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib20","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.ijrobp.2007.04.018","article-title":"Accelerated intensity-modulated radiotherapy to breast in prone position: dosimetric results","volume":"68","author":"DeWyngaert","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib21","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1200\/JCO.2006.09.1041","article-title":"Phase I-II trial of\u00a0prone accelerated intensity modulated radiation therapy to the\u00a0breast to optimally spare normal tissue","volume":"25","author":"Formenti","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib22","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.ijrobp.2009.07.1683","article-title":"Interfraction and intrafraction setup variability for prone breast radiation therapy","volume":"76","author":"Mitchell","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib23","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.radonc.2011.09.008","article-title":"Comparison of three-dimensional versus intensity-modulated radiotherapy techniques to treat breast and axillary level III and supraclavicular nodes in a prone versus supine position","volume":"102","author":"Sethi","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib24","doi-asserted-by":"crossref","first-page":"e415","DOI":"10.1016\/j.ijrobp.2011.06.1950","article-title":"Prone hypofractionated whole-breast radiotherapy without a boost to the tumor bed: comparable toxicity of IMRT versus a 3D conformal technique","volume":"82","author":"Hardee","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib25","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.ijrobp.2012.01.040","article-title":"Prospective assessment of optimal individual position (prone versus supine) for breast radiotherapy: volumetric and dosimetric correlations in 100\u00a0patients","volume":"84","author":"Lymberis","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib26","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3389\/fonc.2012.00044","article-title":"Comparison of Acute and Late Toxicity of Two Regimens of 3- and 5-Week Concomitant Boost Prone IMRT to Standard 6-Week Breast Radiotherapy","volume":"2","author":"Raza","year":"2012","journal-title":"Front Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib27","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.ijrobp.2015.12.373","article-title":"Prospective Randomized Trial of Prone Accelerated Intensity Modulated Breast Radiation Therapy With a Daily Versus Weekly Boost to the Tumor Bed","volume":"95","author":"Cooper","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib28","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1016\/j.prro.2015.10.022","article-title":"Breast, chest wall, and nodal irradiation with prone set-up: Results of a hypofractionated trial with a median follow-up of 35 months","volume":"6","author":"Shin","year":"2016","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib29","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.radonc.2017.01.008","article-title":"A cardiac contouring atlas for radiotherapy","volume":"122","author":"Duane","year":"2017","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ijrobp.2009.10.058","article-title":"Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer","volume":"79","author":"Feng","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2020.01.001_bib31","author":"White"},{"key":"10.1016\/j.prro.2020.01.001_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.prro.2013.07.005","article-title":"Breathing adapted radiation therapy in comparison with prone position to reduce the doses to the heart, left anterior descending coronary artery, and contralateral breast in whole breast radiation therapy","volume":"4","author":"Verhoeven","year":"2014","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib33","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.radonc.2014.11.018","article-title":"The UK HeartSpare\u00a0Study (Stage IB): Randomised comparison of a voluntary breath-hold technique and prone radiotherapy after breast conserving surgery","volume":"114","author":"Bartlett","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2020.01.001_bib34","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.radonc.2010.05.014","article-title":"Prone versus supine positioning for whole and partial-breast radiotherapy: A comparison of nontarget tissue dosimetry","volume":"96","author":"Kirby","year":"2010","journal-title":"Radiother Oncol"}],"container-title":["Practical Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850020300011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850020300011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:23:17Z","timestamp":1761819797000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879850020300011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1879850020300011"],"URL":"https:\/\/doi.org\/10.1016\/j.prro.2020.01.001","relation":{},"ISSN":["1879-8500"],"issn-type":[{"value":"1879-8500","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Prospective Trial to Compare Deep Inspiratory Breath Hold With Prone Breast Irradiation","name":"articletitle","label":"Article Title"},{"value":"Practical Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prro.2020.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}