{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:30:24Z","timestamp":1791689424636,"version":"4.3.4"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"am","delay-in-days":353,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5P30CA016672-45"],"award-info":[{"award-number":["5P30CA016672-45"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019971","name":"Dr. Marnie Rose Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019971","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["practicalradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Radiation Oncology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.prro.2022.12.006","type":"journal-article","created":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T11:12:22Z","timestamp":1672485142000},"page":"231-238","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Adults"],"prefix":"10.1016","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5286-0649","authenticated-orcid":false,"given":"Susan L.","family":"McGovern","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dershan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kham","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Frances","family":"McAleer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra","family":"Yeboa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Grosshans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amol J.","family":"Ghia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juhee","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Thall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Mahajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prro.2022.12.006_bib0001","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.critrevonc.2018.03.024","article-title":"Re-irradiation as salvage treatment in recurrent glioblastoma: A comprehensive literature review to provide practical answers to frequently asked questions","volume":"126","author":"Scoccianti","year":"2018","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.prro.2022.12.006_bib0002","first-page":"144","article-title":"Re-irradiation for recurrent high-grade gliomas: A systematic review and analysis of treatment technique with respect to survival and risk of radionecrosis","volume":"6","author":"Shanker","year":"2019","journal-title":"Neurooncol Pract"},{"key":"10.1016\/j.prro.2022.12.006_bib0003","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.ijrobp.2007.08.015","article-title":"Reirradiation tolerance of the human brain","volume":"70","author":"Mayer","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2022.12.006_bib0004","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3390\/cancers4020379","article-title":"External beam radiotherapy of recurrent glioma: Radiation tolerance of the human brain","volume":"4","author":"Sminia","year":"2012","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.prro.2022.12.006_bib0005","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.radonc.2019.06.009","article-title":"Bevacizumab reduces toxicity of reirradiation in recurrent high-grade glioma","volume":"138","author":"Fleischmann","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0006","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1056\/NEJMoa1308573","article-title":"A randomized trial of bevacizumab for newly diagnosed glioblastoma","volume":"370","author":"Gilbert","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2022.12.006_bib0007","first-page":"205","article-title":"Response assessment in neuro-oncology (RANO): More than imaging criteria for malignant glioma","volume":"2","author":"Chang","year":"2015","journal-title":"Neurooncol Pract"},{"key":"10.1016\/j.prro.2022.12.006_bib0008","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"10.1016\/j.prro.2022.12.006_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: Building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J Biomed Inform"},{"key":"10.1016\/j.prro.2022.12.006_bib0010","doi-asserted-by":"crossref","DOI":"10.1201\/b16018","author":"Gelman","year":"2013","journal-title":"Bayesian Data Analysis"},{"key":"10.1016\/j.prro.2022.12.006_bib0011","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.prro.2022.12.006_bib0012","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ijrobp.2017.06.2466","article-title":"Multicenter, phase 1, dose escalation study of hypofractionated stereotactic radiation therapy with bevacizumab for recurrent glioblastoma and anaplastic astrocytoma","volume":"99","author":"Clarke","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2022.12.006_bib0013","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0180457","article-title":"Modification and optimization of an established prognostic score after re-irradiation of recurrent glioma","volume":"12","author":"Kessel","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.prro.2022.12.006_bib0014","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1186\/1748-717X-8-287","article-title":"Analysis of equivalent uniform dose (EUD) and conventional radiation treatment parameters after primary and re-irradiation of malignant glioma","volume":"8","author":"Niyazi","year":"2013","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0015","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s11060-017-2392-1","article-title":"The evolving role for re-irradiation in the management of recurrent grade 4 glioma","volume":"134","author":"Howard","year":"2017","journal-title":"J Neurooncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0016","first-page":"33","article-title":"The role of large volume re-irradiation with bevacizumab in chemorefractory high grade glioma","volume":"22","author":"Chan","year":"2020","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0017","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s11060-010-0336-0","article-title":"Unexpected late radiation neurotoxicity following bevacizumab use: A case series","volume":"102","author":"Kelly","year":"2011","journal-title":"J Neurooncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0018","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1212\/WNL.0b013e3181c3fd00","article-title":"Optic neuropathy in patients with glioblastoma receiving bevacizumab","volume":"73","author":"Sherman","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.prro.2022.12.006_bib0019","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000061231","article-title":"Hyperfractionated reirradiation for malignant glioma","volume":"33","author":"Neider","year":"1999","journal-title":"Front Radiat Ther Oncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0020","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13014-021-01767-9","article-title":"Current status and recent advances in reirradiation of glioblastoma","volume":"16","author":"Minniti","year":"2021","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.prro.2022.12.006_bib0021","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1055\/s-0039-1694052","article-title":"Patient outcomes after reirradiation of small skull base tumors using stereotactic body radiotherapy, intensity modulated radiotherapy, or proton therapy","volume":"81","author":"Ng","year":"2020","journal-title":"J Neurol Surg B Skull Base"}],"container-title":["Practical Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850022003915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850022003915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:24:47Z","timestamp":1761819887000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879850022003915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S1879850022003915"],"URL":"https:\/\/doi.org\/10.1016\/j.prro.2022.12.006","relation":{},"ISSN":["1879-8500"],"issn-type":[{"value":"1879-8500","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Adults","name":"articletitle","label":"Article Title"},{"value":"Practical Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prro.2022.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}