{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T08:38:21Z","timestamp":1784709501061,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","award":["2021SFGC05012021"],"award-info":[{"award-number":["2021SFGC05012021"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272753"],"award-info":[{"award-number":["82272753"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021LZL002"],"award-info":[{"award-number":["ZR2021LZL002"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["flzh202103"],"award-info":[{"award-number":["flzh202103"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","practicalradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Practical Radiation Oncology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.prro.2025.03.005","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T04:12:31Z","timestamp":1742357551000},"page":"485-496","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Patterns of Recurrence After D2 Radical Surgery for Gastric Cancer: Implications for Postoperative Radiation Therapy"],"prefix":"10.1016","volume":"15","author":[{"given":"Wenheng","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haohua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunli","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinming","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5242-6554","authenticated-orcid":false,"given":"Jinbo","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.prro.2025.03.005_bib0001","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/CM9.0000000000001474","article-title":"Changing profiles of cancer burden worldwide and in China: A secondary analysis of the global cancer statistics 2020","volume":"134","author":"Cao","year":"2021","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.prro.2025.03.005_bib0002","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa010187","article-title":"Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction","volume":"345","author":"Macdonald","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2025.03.005_bib0003","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1200\/JCO.2014.58.3930","article-title":"Phase III trial to compare adjuvant chemotherapy with capecitabine and cisplatin versus concurrent chemoradiotherapy in gastric cancer: Final report of the adjuvant chemoradiotherapy in stomach tumors trial, including survival and subset analyses","volume":"33","author":"Park","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0004","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.annonc.2020.11.017","article-title":"A randomized phase III trial comparing adjuvant single-agent S1, S-1 with oxaliplatin, and postoperative chemoradiation with S-1 and oxaliplatin in patients with node-positive gastric cancer after D2 resection: The ARTIST 2 trial","volume":"32","author":"Park","year":"2021","journal-title":"Ann Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0005","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12957-016-0957-7","article-title":"Postoperative chemoradiotherapy versus chemotherapy for R0 resected gastric cancer with D2 lymph node dissection: An up-to-date meta-analysis","volume":"14","author":"Zhou","year":"2016","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0006","doi-asserted-by":"crossref","first-page":"4724","DOI":"10.1002\/cam4.3085","article-title":"Patterns of recurrence after curative D2 resection for gastric cancer: Implications for postoperative radiotherapy","volume":"9","author":"Xu","year":"2020","journal-title":"Cancer Med"},{"key":"10.1016\/j.prro.2025.03.005_bib0007","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.radonc.2018.07.002","article-title":"Necessity of adjuvant concurrent chemo-radiotherapy in D2-resected LN-positive gastric cancer","volume":"129","author":"Yu","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0008","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1002\/cam4.873","article-title":"D2-resected stage IIIc gastric cancer patients benefit from adjuvant chemoradiotherapy","volume":"5","author":"Peng","year":"2016","journal-title":"Cancer Med"},{"key":"10.1016\/j.prro.2025.03.005_bib0009","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20150758","article-title":"Identification of patients with lymph node metastasis from gastric cancer who may benefit from adjuvant chemoradiotherapy after D2 dissection\u2013do N3 patients benefit from additional radiation?","volume":"89","author":"Fan","year":"2016","journal-title":"Br J Radiol"},{"key":"10.1016\/j.prro.2025.03.005_bib0010","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.2147\/CMAR.S195130","article-title":"Adjuvant chemoradiotherapy versus adjuvant chemotherapy for patients with N3 gastric cancer after D2\/R0 resection: A retrospective study based on propensity score analyses","volume":"11","author":"Zhou","year":"2019","journal-title":"Cancer Manag Res"},{"key":"10.1016\/j.prro.2025.03.005_bib0011","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1016\/j.ijrobp.2024.07.072","article-title":"Long-term prognostic analysis of chemoradiotherapy vs. chemotherapy after D2 resection for high-risk gastric cancer: Results from a prospective randomized control study","volume":"120","author":"Qiao","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2025.03.005_bib0012","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S1470-2045(10)70070-X","article-title":"Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial","volume":"11","author":"Songun","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0013","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.radonc.2012.08.017","article-title":"Patterns of regional recurrence after curative D2 resection for stage III (N3) gastric cancer: Implications for postoperative radiotherapy","volume":"104","author":"Chang","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0014","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13014-019-1332-y","article-title":"Competing risk nomogram predicting initial loco-regional recurrence in gastric cancer patients after D2 gastrectomy","volume":"14","author":"Wang","year":"2019","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0015","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0360-3016(01)02646-3","article-title":"Gastric surgical adjuvant radiotherapy consensus report: Rationale and treatment implementation","volume":"52","author":"Smalley","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2025.03.005_bib0016","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1053\/srao.2002.30827","article-title":"Radiation treatment parameters in the adjuvant postoperative therapy of gastric cancer","volume":"12","author":"Tepper","year":"2002","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0017","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ijrobp.2007.09.055","article-title":"A new suggestion for the radiation target volume after a subtotal gastrectomy in patients with stomach cancer","volume":"71","author":"Nam","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.prro.2025.03.005_bib0018","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.radonc.2013.05.025","article-title":"Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation","volume":"108","author":"Yoon","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0019","doi-asserted-by":"crossref","first-page":"8015","DOI":"10.2147\/OTT.S177315","article-title":"Patterns of regional nodal relapse after D2 lymphadenectomy in gastric cancer: Rethinking the target volume","volume":"11","author":"Yang","year":"2018","journal-title":"Onco Targets Ther"},{"key":"10.1016\/j.prro.2025.03.005_bib0020","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1634\/theoncologist.2016-0239","article-title":"Does a higher cutoff value of lymph node retrieval substantially improve survival in patients with advanced gastric cancer?-Time to embrace a new digit","volume":"22","author":"Liu","year":"2017","journal-title":"Oncologist"},{"key":"10.1016\/j.prro.2025.03.005_bib0021","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.radonc.2010.04.031","article-title":"Pattern of lymph node metastases and its implication in radiotherapeutic clinical target volume delineation of regional lymph node in patients with gastric carcinoma","volume":"96","author":"Yi","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0022","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/00000658-198911000-00005","article-title":"Lymph node metastases of gastric cancer. General pattern in 1931 patients","volume":"210","author":"Maruyama","year":"1989","journal-title":"Ann Surg"},{"key":"10.1016\/j.prro.2025.03.005_bib0023","doi-asserted-by":"crossref","first-page":"86","DOI":"10.5230\/jgc.2011.11.2.86","article-title":"Clinical significance of the pattern of lymph node metastasis depending on the location of gastric cancer","volume":"11","author":"Han","year":"2011","journal-title":"J Gastric Cancer"},{"key":"10.1016\/j.prro.2025.03.005_bib0024","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.radonc.2015.08.009","article-title":"Effects of adjuvant radiotherapy on completely resected gastric cancer: A radiation oncologist's view of the ARTIST randomized phase III trial","volume":"117","author":"Yu","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0025","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1056\/NEJMoa2405195","article-title":"Preoperative chemoradiotherapy for resectable gastric cancer","volume":"391","author":"Leong","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prro.2025.03.005_bib0026","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41571-024-00960-5","article-title":"The TOPGEAR trial - is chemoradiotherapy no longer a component of multidisciplinary care for gastric cancer?","volume":"22","author":"Badgwell","year":"2025","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.prro.2025.03.005_bib0027","doi-asserted-by":"crossref","first-page":"E507","DOI":"10.1016\/j.ijrobp.2024.07.1125","article-title":"Pathological response and locoregional control in gastric cancer patients after preoperative chemoradiation versus preoperative chemotherapy: Data from the Neo-Crag clinical trial","volume":"120","author":"Jing","year":"2024","journal-title":"Int J Radiat Oncolo Biol Phys"},{"key":"10.1016\/j.prro.2025.03.005_bib0028","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1186\/s12957-016-1042-y","article-title":"The patterns and timing of recurrence after curative resection for gastric cancer in China","volume":"14","author":"Liu","year":"2016","journal-title":"World J Surg Oncol"}],"container-title":["Practical Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850025000700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879850025000700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:04:39Z","timestamp":1778832279000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879850025000700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S1879850025000700"],"URL":"https:\/\/doi.org\/10.1016\/j.prro.2025.03.005","relation":{},"ISSN":["1879-8500"],"issn-type":[{"value":"1879-8500","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patterns of Recurrence After D2 Radical Surgery for Gastric Cancer: Implications for Postoperative Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"Practical Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prro.2025.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society for Radiation Oncology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}