{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T06:46:19Z","timestamp":1772693179476,"version":"3.50.1"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Respiratory Reviews"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.prrv.2021.09.003","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T02:31:32Z","timestamp":1632364292000},"page":"53-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Genes involved in paediatric apnoea and death based on knockout animal models: Implications for sudden infant death syndrome (SIDS)"],"prefix":"10.1016","volume":"44","author":[{"given":"Eliza","family":"Stalley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen A.","family":"Waters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Machaalani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0005","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1542\/peds.114.1.234","article-title":"Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach","volume":"114","author":"Krous","year":"2004","journal-title":"Paediatr"},{"issue":"3-4","key":"10.1016\/j.prrv.2021.09.003_b0010","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000244052","article-title":"A perspective on neuropathologic findings in victims of the Sudden Infant Death Syndrome: the triple risk model","volume":"65","author":"Filiano","year":"1994","journal-title":"Biol Neonate"},{"issue":"4","key":"10.1016\/j.prrv.2021.09.003_b0015","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0095-5108(18)30429-9","article-title":"The cardiorespiratory control hypothesis for sudden infant death syndrome","volume":"19","author":"Hunt","year":"1992","journal-title":"Clin Perinatol"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0020","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev.pathol.4.110807.092322","article-title":"The brainstem and serotonin in the sudden infant death syndrome","volume":"4","author":"Kinney","year":"2009","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.prrv.2021.09.003_b0025","doi-asserted-by":"crossref","first-page":"S383","DOI":"10.1016\/S1526-0542(04)90068-1","article-title":"Apparent life-threatening events and sudden infant death on a monitor","volume":"5","author":"Poets","year":"2004","journal-title":"Paediatr Respir Rev"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0030","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1203\/00006450-199902000-00002","article-title":"Neuronal apoptosis in sudden infant death syndrome","volume":"45","author":"Waters","year":"1999","journal-title":"Paediatric Res"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0035","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/brain\/awm290","article-title":"Neuronal cell death in the sudden infant death syndrome brainstem and association with risk factors","volume":"131","author":"Machaalani","year":"2008","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0040","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s12024-018-9954-1","article-title":"Neuronal apoptosis in the brainstem medulla of sudden unexpected death in infancy (SUDI), and the importance of standardized SUDI classification","volume":"14","author":"Ambrose","year":"2018","journal-title":"Forensic Sci Med Pathol"},{"key":"10.1016\/j.prrv.2021.09.003_b0045","first-page":"293","article-title":"Neurochemical abnormalities in the brainstem of the Sudden infant death syndrome","volume":"15","author":"Machaalani","year":"2014","journal-title":"Pediatr Resp Rev"},{"issue":"11","key":"10.1016\/j.prrv.2021.09.003_b0050","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1164\/rccm.200301-134OC","article-title":"Incomplete arousal processes in infants who were victims of sudden death","volume":"168","author":"Kato","year":"2003","journal-title":"Am J Respir Crit Care Med Year"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0055","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1203\/00006450-199903000-00010","article-title":"Gasping and other cardiorespiratory patterns during sudden infant deaths","volume":"45","author":"Poets","year":"1999","journal-title":"Paediatr Res"},{"key":"10.1016\/j.prrv.2021.09.003_b0060","series-title":"SIDS Sudden infant and early childhood death: the past, the present and the future","first-page":"711","article-title":"The genetics of sudden infant death syndrome","author":"Brownstein","year":"2018"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0065","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3390\/genes12020216","article-title":"The genetics of sudden infant death syndrome \u2013 towards a gene reference resource","volume":"12","author":"Johannsen","year":"2021","journal-title":"Genes"},{"key":"10.1016\/j.prrv.2021.09.003_b0070","unstructured":"Hall B, Limaye A, Kulkarni AB. Overview: generation of gene knockout mice. Curr Protoc Cell Biol, Chapter 19, 2010: 12.17."},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0075","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1172\/JCI118828","article-title":"Conditional gene targeting","volume":"98","author":"Rajewsky","year":"1996","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0080","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0306-4522(01)00171-3","article-title":"Translating developmental time across mammalian species","volume":"105","author":"Clancy","year":"2001","journal-title":"Neurosci"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0085","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/japplphysiol.00336.2011","article-title":"Failed heart rate recovery at a critical age in 5-HT deficient mice exposed to episodic anoxia: implications for SIDS","volume":"111","author":"Cummings","year":"2011","journal-title":"J Appl Physiol"},{"issue":"6","key":"10.1016\/j.prrv.2021.09.003_b0090","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1152\/japplphysiol.90729.2008","article-title":"Autoresuscitation responses to hypoxia-induced apnea are delayed in newborn 5-HT-deficient Pet-1 homozygous mice","volume":"106","author":"Erickson","year":"2009","journal-title":"J Appl Physiol"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.molmed.2004.11.005","article-title":"Mutations of brainstem transcription factors and central respiratory disorders","volume":"11","author":"Blanchi","year":"2005","journal-title":"Trends Mol Med"},{"issue":"12","key":"10.1016\/j.prrv.2021.09.003_b0100","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1152\/japplphysiol.00003.2013","article-title":"Time- and age-depedent effects of serotonin on gasping and autoresuscitation in neonatal mice","volume":"114","author":"Chen","year":"2013","journal-title":"J Appl Physiol"},{"issue":"17","key":"10.1016\/j.prrv.2021.09.003_b0105","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1001\/jama.296.17.2124","article-title":"Multiple serotonergic brainstem abnormalities in sudden infant death syndrome","volume":"296","author":"Paterson","year":"2006","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.prrv.2021.09.003_b0110","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.yjmcc.2009.07.021","article-title":"Serotonin transporter gene deficiency is associated with sudden death of mice through activation of TGF-beta1 signalling","volume":"47","author":"Pavone","year":"2009","journal-title":"J Mol Cell Cardiol"},{"issue":"6","key":"10.1016\/j.prrv.2021.09.003_b0115","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/jnc.12311","article-title":"Development of brainstem 5-HT1A receptor binding sites in serotonin-deficient mice","volume":"126","author":"Massey","year":"2013","journal-title":"J Neurochem"},{"issue":"33","key":"10.1016\/j.prrv.2021.09.003_b0120","doi-asserted-by":"crossref","first-page":"10341","DOI":"10.1523\/JNEUROSCI.1963-09.2009","article-title":"Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development","volume":"29","author":"Hodges","year":"2009","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0125","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1152\/jn.00213.2015","article-title":"5-HT2A receptor activation is necessary for CO2 induced arousal","volume":"114","author":"Buchanan","year":"2015","journal-title":"J Neurophys"},{"issue":"12","key":"10.1016\/j.prrv.2021.09.003_b0130","doi-asserted-by":"crossref","first-page":"24380","DOI":"10.3390\/ijms141224380","article-title":"Cardiac ablation of Rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice","volume":"14","author":"Cao","year":"2013","journal-title":"Int J Mol Sci"},{"issue":"9","key":"10.1016\/j.prrv.2021.09.003_b0135","doi-asserted-by":"crossref","DOI":"10.1161\/ATVBAHA.117.309089","article-title":"Deletion of Fstl1 (Follistatin-Like 1) from the endocardial\/endothelial lineage causes mitral valve disease","volume":"37","author":"Prakash","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.prrv.2021.09.003_b0140","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.yjmcc.2017.02.003","article-title":"BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility","volume":"105","author":"Willis","year":"2017","journal-title":"J Mol Cell Cardiol"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0145","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.bbrc.2014.08.046","article-title":"Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice","volume":"452","author":"Zhang","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"issue":"10","key":"10.1016\/j.prrv.2021.09.003_b0150","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1093\/cvr\/cvz251","article-title":"Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart","volume":"116","author":"Oka","year":"2020","journal-title":"Cardiovasc Res"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0155","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ydbio.2014.02.010","article-title":"Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death","volume":"388","author":"VanDusen","year":"2014","journal-title":"Dev Biol"},{"issue":"6","key":"10.1016\/j.prrv.2021.09.003_b0160","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/CIRCEP.109.894683","article-title":"Sudden infant death syndrome in mice with an inherited mutation in RyR2","volume":"2","author":"Mathur","year":"2009","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"6","key":"10.1016\/j.prrv.2021.09.003_b0165","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.hrthm.2007.02.026","article-title":"A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors","volume":"4","author":"Tester","year":"2007","journal-title":"Heart Rhythm"},{"issue":"50","key":"10.1016\/j.prrv.2021.09.003_b0170","doi-asserted-by":"crossref","first-page":"12661","DOI":"10.1523\/JNEUROSCI.0557-16.2016","article-title":"Deficiency of CPEB2-confined choline acetyltransferase expression in the dorsal motor nucleus of vagus causes hyperactivated parasympathetic signaling-associated bronchoconstriction","volume":"36","author":"Lai","year":"2016","journal-title":"J Neurosci"},{"key":"10.1016\/j.prrv.2021.09.003_b0175","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1113\/jphysiol.2003.052514","article-title":"Sudden neonatal death in PACAP-deficient mice is associated with reduced respiratory chemoresponse and susceptibility to apnoea","volume":"555","author":"Cummings","year":"2004","journal-title":"J Physiol"},{"key":"10.1016\/j.prrv.2021.09.003_b0180","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.nbd.2017.04.002","article-title":"Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 (PAC1) in the human infant brain and changes in the Sudden Infant Death Syndrome (SIDS)","volume":"103","author":"Huang","year":"2017","journal-title":"Neurobiol Dis"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0185","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1651-2227.2008.01131.x","article-title":"Sudden infant death syn drome (SIDS) in African Americans: polymorphisms in the gene encoding the stress peptide pituitary adenylate cyclase-activating polypeptide (PACAP)","volume":"98","author":"Cummings","year":"2009","journal-title":"Acta Paediatr"},{"issue":"5","key":"10.1016\/j.prrv.2021.09.003_b0190","first-page":"151","article-title":"Impaired neonatal cardiorespiratory responses to hypoxia in mice lacking PAC1 or VPAC2 receptors","volume":"316","author":"Barrett","year":"2019","journal-title":"Am J Phsyiol Regul Comp Physiol"},{"issue":"20","key":"10.1016\/j.prrv.2021.09.003_b0195","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1161\/01.CIR.0000147235.53360.59","article-title":"Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice","volume":"110","author":"Otto","year":"2004","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.prrv.2021.09.003_b0200","doi-asserted-by":"crossref","first-page":"e546","DOI":"10.1111\/apa.12405","article-title":"Analysis of PAC1 receptor gene variants in Caucasian and African American infants dying of sudden infant death syndrome","volume":"102","author":"Barrett","year":"2013","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.prrv.2021.09.003_b0205","doi-asserted-by":"crossref","unstructured":"Schoor M, Schuster-Gossler K, Roopenian D, Gossler A. Skeletal dysplasias, growth retardation, reduced postnatal survival, and impaired fertility in mice lacking the SNF2\/SWI2 family member ETL1. Mech Dev1999:85(1-2):73-83.","DOI":"10.1016\/S0925-4773(99)00090-8"},{"issue":"17","key":"10.1016\/j.prrv.2021.09.003_b0210","doi-asserted-by":"crossref","first-page":"5361","DOI":"10.1523\/JNEUROSCI.16-17-05361.1996","article-title":"Mice lacking BDNF exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing","volume":"16","author":"Erickson","year":"1996","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0215","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.resp.2011.10.004","article-title":"Expression of brain-derived neurotrophic factor and TrkB receptor in the sudden infant death syndrome brainstem","volume":"180","author":"Tang","year":"2012","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.prrv.2021.09.003_b0220","doi-asserted-by":"crossref","first-page":"104759","DOI":"10.1016\/j.nbd.2020.104759","article-title":"Neuron-specific Kv1.1 deficiency is sufficient to cause epilepsy, premature death, and cardiorespiratory dysregulation","volume":"137","author":"Trosclair","year":"2020","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.prrv.2021.09.003_b0225","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.nbd.2019.04.006","article-title":"Cardiorespiratory profiling reveals primary breathing dysfunction in Kcna1-null mice: implications for sudden unexpected death in epilepsy","volume":"127","author":"Dhaibar","year":"2019","journal-title":"Neurobiol Dis"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0230","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/epi.13971","article-title":"Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy","volume":"59","author":"Simeone","year":"2018","journal-title":"Epilepsia"},{"issue":"282","key":"10.1016\/j.prrv.2021.09.003_b0235","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaa4050","article-title":"Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models","volume":"7","author":"Aiba","year":"2015","journal-title":"Sci Transl Med"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0240","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.brainres.2005.06.039","article-title":"Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice","volume":"1052","author":"Xie","year":"2005","journal-title":"Brain Res"},{"key":"10.1016\/j.prrv.2021.09.003_b0245","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.eplepsyres.2016.04.002","article-title":"Altered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2(+\/Q390X) mice associated with epileptic encephalopathy","volume":"123","author":"Xia","year":"2016","journal-title":"Epilepsy Res"},{"issue":"1-3","key":"10.1016\/j.prrv.2021.09.003_b0250","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.resp.2005.06.011","article-title":"The role of respiratory control disorders in SIDS","volume":"149","author":"Thach","year":"2005","journal-title":"Resp Physiol Neurobiol"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0255","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/ejn.12054","article-title":"Impaired response to hypoxia in the respiratory centre is a major cause of neonatal death of the PACAP-knockout mouse","volume":"37","author":"Arata","year":"2013","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.prrv.2021.09.003_b0260","first-page":"4","article-title":"PACAP drives cardiorespiratory responses to heat stress in neonatal mice","volume":"313","author":"Barrett","year":"2017","journal-title":"Am J Physiol"},{"key":"10.1016\/j.prrv.2021.09.003_b0265","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.neuro.2017.05.005","article-title":"Hypoxia and nicotine effects on PACAP and its receptor PAC1 in the developing piglet brainstem","volume":"62","author":"Huang","year":"2017","journal-title":"Neurotoxicol"},{"key":"10.1016\/j.prrv.2021.09.003_b0270","first-page":"271","article-title":"Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention","volume":"10","author":"Massey","year":"2014","journal-title":"Neurology"},{"issue":"10","key":"10.1016\/j.prrv.2021.09.003_b0275","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1152\/japplphysiol.00939.2012","article-title":"Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal development","volume":"113","author":"Barrett","year":"2012","journal-title":"J Appl Physiol"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0280","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1152\/japplphysiol.91461.2008","article-title":"Genesis of gasping is independent of levels of serotonin in the Pet-1 knockout mouse","volume":"107","author":"St.-John","year":"2009","journal-title":"J Appl Physiol"},{"issue":"4","key":"10.1016\/j.prrv.2021.09.003_b0285","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1152\/japplphysiol.00439.2017","article-title":"Active sleep unmasks apnoea and delayed arousal in infant rat pups lacking central serotonin","volume":"123","author":"Young","year":"2017","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.prrv.2021.09.003_b0290","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/japplphysiol.00336.2011","article-title":"Bradycardia in serotonin deficient Pet-1 -\/- mice: influence of respiratory dysfunction and hyperthermia over first 2 postnatal weeks","volume":"111","author":"Cummings","year":"2010","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.prrv.2021.09.003_b0295","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.brainres.2008.07.039","article-title":"Brain-derived Neurotrophic Factor (BDNF) and TrkB in the piglet brainstem after postnatal nicotine and intermittent hypercapnic hypoxia","volume":"1232","author":"Tang","year":"2008","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0300","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1651-2227.2010.01960.x","article-title":"The brain-derived neutrophic factor val66met polymorphism and sudden unexpected infant death","volume":"100","author":"Opdal","year":"2011","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.prrv.2021.09.003_b0305","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1528-1167.2011.03358.x","article-title":"Unifying the definitions of sudden unexpected death in epilepsy","volume":"53","author":"Nashef","year":"2012","journal-title":"Epilepsia"},{"issue":"4","key":"10.1016\/j.prrv.2021.09.003_b0310","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.tins.2019.02.002","article-title":"Impaired CO2 induced arousal in SIDS and SUDEP","volume":"42","author":"Buchanan","year":"2019","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.prrv.2021.09.003_b0315","doi-asserted-by":"crossref","unstructured":"Kinney HC, Haynes RL, Armstrong D, Goldstein. Abnormalities of the hippocampus in sudden and unexpected death in early life. In: Duncan JR, Byard RW. SIDS Sudden infant and early childhood death: the past, the present and the future. Adelaide(AU): University of Adelaide Press; 2018:661-689.","DOI":"10.20851\/sids-29"},{"key":"10.1016\/j.prrv.2021.09.003_b0320","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1093\/brain\/awy078","article-title":"The ventrolateral medulla and medullary raphe in sudden unexpected death in epilepsy","volume":"141","author":"Patodia","year":"2018","journal-title":"Brain"},{"issue":"8","key":"10.1016\/j.prrv.2021.09.003_b0325","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/epi.14513","article-title":"Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy","volume":"59","author":"Wallace","year":"2018","journal-title":"Epilepsia"},{"key":"10.1016\/j.prrv.2021.09.003_b0330","first-page":"6","article-title":"Sudden infant death syndrome due to long QT syndrome: A brief review of the genetic substrate and prevalence","volume":"24","author":"Ioakeimidis","year":"2017","journal-title":"J Biol Res"},{"issue":"4","key":"10.1016\/j.prrv.2021.09.003_b0335","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1056\/NEJM200007273430405","article-title":"A molecular link between the sudden infant death syndrome and the long-QT syndrome","volume":"343","author":"Schwartz","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.prrv.2021.09.003_b0340","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2147\/TACG.S239478","article-title":"Genetic factors underlying sudden infant death syndrome","volume":"14","author":"Keywan","year":"2021","journal-title":"Appl Clin Genet"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0345","first-page":"503","article-title":"A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome","volume":"6","author":"Neary","year":"2013","journal-title":"Dis Model Mech"},{"issue":"6","key":"10.1016\/j.prrv.2021.09.003_b0350","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1523\/JNEUROSCI.4395-06.2007","article-title":"Developmental cell death is enhanced in the cerebral cortex of mice lacking the brain vesicular monoamine transporter","volume":"27","author":"Stankovski","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.prrv.2021.09.003_b0355","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.brainres.2007.12.032","article-title":"Neuroprotective effects of serotonin 5-HT1a receptor activation against ischemic cell damage in gerbil hippocampus: involvement of NMDA receptor NR1 subunit and BDNF","volume":"1199","author":"Salazar-Colocho","year":"2008","journal-title":"Brain Res"},{"issue":"3","key":"10.1016\/j.prrv.2021.09.003_b0360","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF03165783","volume":"63","author":"Salazar-Colocho","year":"2007","journal-title":"J Physiol Biochem"},{"issue":"1","key":"10.1016\/j.prrv.2021.09.003_b0365","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0167-4889(03)00023-5","article-title":"The G protein-coupled 5-HT1A receptor causes suppression of capsase 3 through MAPK and protein kinase Calpha","volume":"1640","author":"Adayev","year":"2003","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0370","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1471-4159.2009.06555.x","article-title":"Balanced effect of PACAP and Fas on granule cell death during cerebellar development: a morphological, functional and behavioural characterisation","volume":"113","author":"Allais","year":"2010","journal-title":"J Neurochem"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0375","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.10.013","article-title":"Neuroprotective effects of brain derived neurotrophic factor and noggin-modified bone mesenchymal stem cells in focal cerebral ischemia in rats","volume":"25","author":"Lu","year":"2016","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"2","key":"10.1016\/j.prrv.2021.09.003_b0380","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0165-3806(94)00220-T","article-title":"Brain derived neurotrophic factor can prevent apoptosis of rat cerebellar granule neurons in culture","volume":"85","author":"Kubo","year":"1995","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1016\/j.prrv.2021.09.003_b0385","unstructured":"S. Fishilevich et al. GeneHancer: genome-wide integration of enhancers and target genes in GeneCards Database. 2021;2021 <https:\/\/www.genecards.org\/cgi-bin\/carddisp.pl?gene=FEV\u2265."},{"key":"10.1016\/j.prrv.2021.09.003_b0390","unstructured":"Huret JL et al. Atlas of Genetics and Cytogeneitcs in Oncology and Haematology. 2021;2021 <http:\/\/atlasgeneticsoncology.org\/Genes\/GC_ADCYAP1.html>."},{"issue":"4","key":"10.1016\/j.prrv.2021.09.003_b0395","first-page":"G731","article-title":"Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum","volume":"275","author":"Fujimiya","year":"1998","journal-title":"Am J Physiol"},{"issue":"23","key":"10.1016\/j.prrv.2021.09.003_b0400","doi-asserted-by":"crossref","first-page":"13355","DOI":"10.1073\/pnas.231094498","article-title":"Altered psychomotor behaviours in mice lacking pituitary adenylate cyclase activating polypeptide (PACAP)","volume":"98","author":"Hashimoto","year":"2001","journal-title":"PNAS"}],"container-title":["Paediatric Respiratory Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526054221000919?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526054221000919?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T19:37:40Z","timestamp":1761507460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526054221000919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":80,"alternative-id":["S1526054221000919"],"URL":"https:\/\/doi.org\/10.1016\/j.prrv.2021.09.003","relation":{},"ISSN":["1526-0542"],"issn-type":[{"value":"1526-0542","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genes involved in paediatric apnoea and death based on knockout animal models: Implications for sudden infant death syndrome (SIDS)","name":"articletitle","label":"Article Title"},{"value":"Paediatric Respiratory Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.prrv.2021.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}