{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:10:03Z","timestamp":1759335003020,"version":"build-2065373602"},"reference-count":46,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Michael E. Debakey VA Medical Center"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychiatric Clinics of North America"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.psc.2019.10.014","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T21:33:30Z","timestamp":1576618410000},"page":"199-211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Psychotherapy for Mixed Depression and Mixed Mania"],"prefix":"10.1016","volume":"43","author":[{"given":"Brittany","family":"O\u2019Brien","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delphine","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan C.","family":"Swann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay J.","family":"Mathew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marijn","family":"Lijffijt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psc.2019.10.014_bib1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1017\/S2045796015000189","article-title":"Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys","volume":"24","author":"Kessler","year":"2015","journal-title":"Epidemiol Psychiatr Sci"},{"key":"10.1016\/j.psc.2019.10.014_bib2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archgenpsychiatry.2011.12","article-title":"Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative","volume":"68","author":"Merikangas","year":"2011","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib3","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.jad.2017.09.006","article-title":"Mixed symptoms in major depressive and bipolar disorders: a systematic review","volume":"225","author":"V\u00e1zquez","year":"2018","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0165-0327(01)00447-5","article-title":"Structure of mania: depressive, irritable, and psychotic clusters with different retrospectively-assessed course patterns of illness in randomized clinical trial participants","volume":"67","author":"Swann","year":"2001","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib5","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/j.2051-5545.2009.tb00245.x","article-title":"Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features","volume":"8","author":"Swann","year":"2009","journal-title":"World Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jad.2005.12.049","article-title":"The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention","volume":"91","author":"Bal\u00e1zs","year":"2006","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-244X-9-33","article-title":"Mixed states vs. pure mania in the French sample of the EMBLEM study: results at baseline and 24\u00a0months--European mania in bipolar longitudinal evaluation of medication","volume":"9","author":"Azorin","year":"2009","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib8","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1038\/s41386-018-0180-z","article-title":"Do baseline sub-threshold hypomanic symptoms affect acute-phase antidepressant outcome in outpatients with major depressive disorder? Preliminary findings from the randomized CO-MED trial","volume":"43","author":"Jha","year":"2018","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.psc.2019.10.014_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s40345-016-0056-2","article-title":"Current irritability associated with hastened depressive recurrence and delayed depressive recovery in bipolar disorder","volume":"4","author":"Yuen","year":"2016","journal-title":"Int J Bipolar Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib10","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/acps.12896","article-title":"Mixed states in bipolar and major depressive disorders: systematic review and quality appraisal of guidelines","volume":"138","author":"Verdolini","year":"2018","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.psc.2019.10.014_bib11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/wps.20089","article-title":"Adding psychotherapy to antidepressant medication in depression and anxiety disorders: a meta-analysis","volume":"13","author":"Cuijpers","year":"2014","journal-title":"World Psychiatry"},{"issue":"9","key":"10.1016\/j.psc.2019.10.014_bib12","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.4088\/JCP.09r05021","article-title":"Adding psychotherapy to pharmacotherapy in the treatment of depressive disorders in adults: a meta-analysis","volume":"70","author":"Cuijpers","year":"2009","journal-title":"J\u00a0Clin Psychiatry"},{"year":"2013","series-title":"Diagnostic and statistical manual of mental disorders","key":"10.1016\/j.psc.2019.10.014_bib13"},{"key":"10.1016\/j.psc.2019.10.014_bib14","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1034\/j.1600-0447.2003.00051.x","article-title":"Frequency of manic symptoms during a depressive episode and unipolar \u201cdepressive mixed state\u201d as bipolar spectrum","volume":"107","author":"Sato","year":"2003","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.psc.2019.10.014_bib15","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1017\/S1092852916000614","article-title":"Exclusion of overlapping symptoms in DSM-5 mixed features specifier: heuristic diagnostic and treatment implications","volume":"22","author":"Malhi","year":"2017","journal-title":"CNS Spectr"},{"key":"10.1016\/j.psc.2019.10.014_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1192\/bjp.bp.112.124404","article-title":"Mixed features of depression: why DSM-5 is wrong (and so was DSM-IV)","volume":"203","author":"Koukopoulos","year":"2013","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jad.2014.03.054","article-title":"Koukopoulos\u05f3 diagnostic criteria for mixed depression: a validation study","volume":"164","author":"Sani","year":"2014","journal-title":"J\u00a0Affect Disord"},{"issue":"3","key":"10.1016\/j.psc.2019.10.014_bib18","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jad.2004.12.004","article-title":"Agitated \u201cunipolar\u201d depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy","volume":"85","author":"Akiskal","year":"2005","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib19","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1016\/S0140-6736(13)60857-0","article-title":"Treatment of bipolar disorder","volume":"381","author":"Geddes","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.psc.2019.10.014_bib20","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s10608-012-9476-1","article-title":"The efficacy of cognitive behavioral therapy: a review of meta-analyses","volume":"36","author":"Hofmann","year":"2012","journal-title":"Cognit Ther Res"},{"key":"10.1016\/j.psc.2019.10.014_bib21","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1176\/appi.psychotherapy.2006.60.3.233","article-title":"Cognitive-behavioral therapy and psychodynamic psychotherapy: techniques, efficacy, and indications","volume":"60","author":"Leichsenring","year":"2006","journal-title":"Am J Psychother"},{"key":"10.1016\/j.psc.2019.10.014_bib22","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jad.2017.08.025","article-title":"The effectiveness of adjunct mindfulness-based intervention in treatment of bipolar disorder: a systematic review and meta-analysis","volume":"225","author":"Chu","year":"2018","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.psc.2019.10.014_bib23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1037\/a0018555","article-title":"The effect of mindfulness-based therapy on anxiety and depression: a meta-analytic review","volume":"78","author":"Hofmann","year":"2010","journal-title":"J\u00a0Consult Clin Psychol"},{"key":"10.1016\/j.psc.2019.10.014_bib24","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S2215-0366(15)00156-X","article-title":"An evidence map of psychosocial interventions for the earliest stages of bipolar disorder","volume":"2","author":"Vallarino","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib25","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.beth.2016.12.006","article-title":"Dialectical behavior therapy group skills training for bipolar disorder","volume":"48","author":"Eisner","year":"2017","journal-title":"Behav Ther"},{"key":"10.1016\/j.psc.2019.10.014_bib26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/brief-treatment\/mhh019","article-title":"Psychoeducation as evidence-based practice: considerations for practice, research, and policy","volume":"4","author":"Lukens","year":"2004","journal-title":"Brief Treat Crisis Interv"},{"key":"10.1016\/j.psc.2019.10.014_bib27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1177\/0145445507304728","article-title":"Cognitive-behavioral interventions to reduce suicide behavior: a systematic review and meta-analysis","volume":"32","author":"Tarrier","year":"2008","journal-title":"Behav Modif"},{"key":"10.1016\/j.psc.2019.10.014_bib28","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1002\/da.22728","article-title":"Cognitive behavioral therapy for anxiety and related disorders: a meta-analysis of randomized placebo-controlled trials","volume":"35","author":"Carpenter","year":"2018","journal-title":"Depress Anxiety"},{"issue":"2","key":"10.1016\/j.psc.2019.10.014_bib29","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1037\/h0100878","article-title":"Dialectical behaviour therapy: description, research and future directions","volume":"5","author":"Swales","year":"2009","journal-title":"Int J Behav Consult Ther"},{"key":"10.1016\/j.psc.2019.10.014_bib30","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.beth.2018.03.009","article-title":"Dialectical behavior therapy is effective for the treatment of suicidal behavior: a meta-analysis","volume":"50","author":"DeCou","year":"2019","journal-title":"Behav Ther"},{"key":"10.1016\/j.psc.2019.10.014_bib31","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1177\/1049731513503047","article-title":"Meta-analysis and systematic review assessing the efficacy of Dialectical Behavior Therapy (DBT)","volume":"24","author":"Panos","year":"2014","journal-title":"Res Soc Work Pract"},{"key":"10.1016\/j.psc.2019.10.014_bib32","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1176\/ajp.136.1.52","article-title":"Use of the research diagnostic criteria and the schedule for affective disorders and schizophrenia to study affective disorders","volume":"136","author":"Endicott","year":"1979","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib33","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1001\/archpsyc.1978.01770310043002","article-title":"A\u00a0diagnostic interview: the schedule for affective disorders and schizophrenia","volume":"35","author":"Endicott","year":"1978","journal-title":"Arch Gen Psychiatry"},{"issue":"1","key":"10.1016\/j.psc.2019.10.014_bib34","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1001\/archpsyc.1981.01780260100011","article-title":"Hamilton depression rating scale. Extracted from regular and change versions of the schedule for affective disorders and schizophrenia","volume":"38","author":"Endicott","year":"1981","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib35","doi-asserted-by":"crossref","DOI":"10.1037\/a0026746","article-title":"Collaborative assessment and management of suicidality in an inpatient setting: results of a pilot study","author":"Ellis","year":"2012","journal-title":"Psychotherapy"},{"key":"10.1016\/j.psc.2019.10.014_bib36","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fpsyt.2014.00083","article-title":"Stress modulates illness-course of substance use disorders: a translational review","volume":"5","author":"Lijffijt","year":"2014","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib37","series-title":"Neurobiology of addiction","first-page":"153","article-title":"Stress and addiction","author":"Lijffijt","year":"2016"},{"key":"10.1016\/j.psc.2019.10.014_bib38","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1017\/S003329170100472X","article-title":"Prodromes, coping strategies and course of illness in bipolar affective disorder--a naturalistic study","volume":"31","author":"Lam","year":"2001","journal-title":"Psychol Med"},{"key":"10.1016\/j.psc.2019.10.014_bib39","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1177\/070674371305800702","article-title":"A\u00a0meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments","volume":"58","author":"Cuijpers","year":"2013","journal-title":"Can J Psychiatry"},{"key":"10.1016\/j.psc.2019.10.014_bib40","doi-asserted-by":"crossref","first-page":"e1001454","DOI":"10.1371\/journal.pmed.1001454","article-title":"Comparative efficacy of seven psychotherapeutic interventions for patients with depression: a network meta-analysis","volume":"10","author":"Barth","year":"2013","journal-title":"PLoS Med"},{"issue":"6","key":"10.1016\/j.psc.2019.10.014_bib41","doi-asserted-by":"crossref","first-page":"e100100","DOI":"10.1371\/journal.pone.0100100","article-title":"Behavioural activation for depression; an update of meta-analysis of effectiveness and sub group analysis","volume":"9","author":"Ekers","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.psc.2019.10.014_bib42","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD010558.pub2","article-title":"Psychological therapies for treatment-resistant depression in adults. Cochrane common mental disorders group","author":"Ijaz","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.psc.2019.10.014_bib43","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1037\/pst0000104","article-title":"Treatment refusal and premature termination in psychotherapy, pharmacotherapy, and their combination: a meta-analysis of head-to-head comparisons","volume":"54","author":"Swift","year":"2017","journal-title":"Psychotherapy"},{"key":"10.1016\/j.psc.2019.10.014_bib44","first-page":"193","article-title":"A\u00a0treatment by disorder meta-analysis of dropout from psychotherapy","volume":"24","author":"Swift","year":"2014","journal-title":"J\u00a0Psychother Integr"},{"key":"10.1016\/j.psc.2019.10.014_bib45","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1749-6632.2009.05146.x","article-title":"The strong relationship between bipolar and substance-use disorder","volume":"1187","author":"Swann","year":"2010","journal-title":"Ann N Y Acad Sci"},{"issue":"1\u20132","key":"10.1016\/j.psc.2019.10.014_bib46","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jad.2010.03.014","article-title":"Dissimilar morbidity following initial mania versus mixed-states in type-I bipolar disorder","volume":"126","author":"Baldessarini","year":"2010","journal-title":"J\u00a0Affect Disord"}],"container-title":["Psychiatric Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0193953X19301091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0193953X19301091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T01:38:23Z","timestamp":1759282703000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0193953X19301091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S0193953X19301091"],"URL":"https:\/\/doi.org\/10.1016\/j.psc.2019.10.014","relation":{},"ISSN":["0193-953X"],"issn-type":[{"type":"print","value":"0193-953X"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Psychotherapy for Mixed Depression and Mixed Mania","name":"articletitle","label":"Article Title"},{"value":"Psychiatric Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psc.2019.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}