{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:46:12Z","timestamp":1786995972832,"version":"build-2736575974"},"reference-count":98,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychiatric Clinics of North America"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.psc.2020.08.010","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T05:13:00Z","timestamp":1603775580000},"page":"745-758","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Obsessive\u2013Compulsive Disorder in Autism Spectrum Disorder Across the Lifespan"],"prefix":"10.1016","volume":"43","author":[{"given":"Markian","family":"Pazuniak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R.","family":"Pekrul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9920","key":"10.1016\/j.psc.2020.08.010_bib1","first-page":"1","article-title":"Autism","volume":"383","author":"Lai","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.psc.2020.08.010_bib2","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.janxdis.2012.06.003","article-title":"The epidemiology of obsessive-compulsive disorder in Spanish Children","volume":"26","author":"Calas","year":"2012","journal-title":"J\u00a0Anxiety Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib3","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0887-6185(00)00048-7","article-title":"Childhood Obsessive-compulsive disorder in the NIMH MECA Study: parent versus child identification of cases","volume":"14","author":"Rapoport","year":"2000","journal-title":"J\u00a0Anxiety Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib4","series-title":"Diagnostic and statistical manual of mental disorders","year":"2013"},{"key":"10.1016\/j.psc.2020.08.010_bib5","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1007\/s10578-017-0717-0","article-title":"Restricted, repetitive behaviors in autism spectrum disorder and obsessive-compulsive disorder: a comparative review","volume":"48","author":"Jiujias","year":"2017","journal-title":"Child Psychiatry Hum Dev"},{"key":"10.1016\/j.psc.2020.08.010_bib6","volume":"vol. IV-TR","year":"2006"},{"key":"10.1016\/j.psc.2020.08.010_bib7","doi-asserted-by":"crossref","first-page":"e0141703","DOI":"10.1371\/journal.pone.0141703","article-title":"Obsessive-Compulsive Disorder and autism spectrum disorders: longitudinal and offspring risk","volume":"10","author":"Meier","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.psc.2020.08.010_bib8","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1007\/s10803-016-2853-y","article-title":"Association of autism spectrum disorder with obsessive-compulsive and attention-deficit\/hyperactivity traits and response inhibition in a community sample","volume":"46","author":"van der Plas","year":"2016","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/cpsp.12009","article-title":"The presentation and classification of anxiety in autism spectrum disorder","volume":"19","author":"Kerns","year":"2012","journal-title":"Clinical Psychol Sci Prac"},{"key":"10.1016\/j.psc.2020.08.010_bib10","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s10567-011-0097-0","article-title":"Anxiety disorder in children and adolescents with autistic spectrum disorders: a meta-analysis","volume":"14","author":"Van Steensel","year":"2011","journal-title":"Clin Child Fam Psychol Rev"},{"key":"10.1016\/j.psc.2020.08.010_bib11","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1080\/j.1440-1614.2005.01637.x","article-title":"Anxiety and social worries in children with Asperger syndrome","volume":"39","author":"Russell","year":"2005","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib12","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1007\/s10803-014-2343-z","article-title":"Variation in the profile of anxiety disorders in boys with an ASD according to method and source of assessment","volume":"45","author":"Bitsika","year":"2015","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib13","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jocrd.2012.04.002","article-title":"Preschool and current autistic symptoms in children and adolescents with obsessive-compulsive disorder (OCD)","volume":"1","author":"Weidle","year":"2012","journal-title":"J\u00a0Obsessive Compuls Relat Disord"},{"issue":"7","key":"10.1016\/j.psc.2020.08.010_bib14","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00787-015-0782-5","article-title":"Subclinical autism spectrum symptoms in pediatric obsessive-compulsive disorder","volume":"25","author":"Arildskov","year":"2016","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib15","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.3109\/00048674.2010.515561","article-title":"Obsessions and compulsions in children with Asperger\u2019s Syndrome or high-functioning Autism: a case-control study","volume":"44","author":"Mack","year":"2010","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib16","first-page":"40","article-title":"Autism spectrum symptoms in children and adolescents with obsessive compulsive disorder and their mothers","volume":"55","author":"Ozyurt","year":"2018","journal-title":"Noro Psikiyatr Ars"},{"key":"10.1016\/j.psc.2020.08.010_bib17","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.janxdis.2007.10.003","article-title":"Autism Spectrum Traits in children and adolescents with obsessive-compulsive disorder (OCD)","volume":"22","author":"Ivarsson","year":"2008","journal-title":"J\u00a0Anxiety Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib18","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s10578-017-0714-3","article-title":"ASD traits among youth with obsessive-compulsive disorder","volume":"48","author":"Griffiths","year":"2017","journal-title":"Child Psychiatry Hum Dev"},{"key":"10.1016\/j.psc.2020.08.010_bib19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0165-1781(02)00304-9","article-title":"Obsessive compulsive behaviors in parents of multiplex autism families","volume":"117","author":"Hollander","year":"2003","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.psc.2020.08.010_bib20","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10578-005-2973-7","article-title":"The relationship between restrictive and repetitive behaviors in individuals with autism and obsessive compulsive symptoms in parents","volume":"36","author":"Abramson","year":"2005","journal-title":"Child Psychiatry Hum Dev"},{"issue":"12","key":"10.1016\/j.psc.2020.08.010_bib21","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s11920-017-0846-y","article-title":"Anxiety disorders and obsessive-compulsive disorder in individuals with autism spectrum disorder","volume":"19","author":"Postorino","year":"2018","journal-title":"Curr Psychiatry Rep"},{"issue":"2","key":"10.1016\/j.psc.2020.08.010_bib22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1177\/1362361307075699","article-title":"An autistic dimension: a proposed subtype of obsessive-compulsive disorder","volume":"11","author":"Bejerot","year":"2007","journal-title":"Autism"},{"issue":"1","key":"10.1016\/j.psc.2020.08.010_bib23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2217\/fnl-2017-0030","article-title":"Comorbid autism spectrum disorder and anxiety disorders: a brief review","volume":"13","author":"Zaboski","year":"2018","journal-title":"Future Neurol"},{"key":"10.1016\/j.psc.2020.08.010_bib24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s10803-006-0158-2","article-title":"Repetitive behaviour in children with high functioning autism and obsessive compulsive disorder","volume":"37","author":"Zandt","year":"2007","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"3","key":"10.1016\/j.psc.2020.08.010_bib25","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/1362361311401763","article-title":"Restricted interests and anxiety in children with autism","volume":"16","author":"Spiker","year":"2012","journal-title":"Autism"},{"key":"10.1016\/j.psc.2020.08.010_bib26","doi-asserted-by":"crossref","first-page":"304","DOI":"10.2174\/1745017901814010304","article-title":"The cognitive profile of persons with obsessive compulsive disorder with and without autism spectrum disorder","volume":"14","author":"Ekman","year":"2018","journal-title":"Clin Pract Epidemiol Ment Health"},{"issue":"4","key":"10.1016\/j.psc.2020.08.010_bib27","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1177\/1362361300004004006","article-title":"A\u00a0psychosocial study on restricted interests in high-functioning persons with pervasive developmental disorders","volume":"4","author":"Mercier","year":"2000","journal-title":"Autism"},{"issue":"4","key":"10.1016\/j.psc.2020.08.010_bib28","first-page":"178","article-title":"Differential Diagnosis between obsessive compulsive disorder and restrictive and repetitive behavioural patterns, activities, and interests in autism spectrum disorders","volume":"6","author":"Paula-Perez","year":"2013","journal-title":"Rev Psiquiatr Salud Ment"},{"key":"10.1016\/j.psc.2020.08.010_bib29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00787-009-0035-6","article-title":"Obsessive-compulsive traits in children and adolescents with Asperger syndrome","volume":"19","author":"Ruta","year":"2010","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib30","series-title":"Psychiatric symptoms and comorbidities in autism spectrum disorder","first-page":"39","article-title":"Repetitive behavior in children with autism spectrum disorder: similarities and differences with obsessive-compulsive disorder","author":"Schaill","year":"2016"},{"issue":"3","key":"10.1016\/j.psc.2020.08.010_bib31","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1177\/0145445513509475","article-title":"Distinguishing obsessive-compulsive behavior from stereotypy: a preliminary investigation","volume":"38","author":"Chok","year":"2014","journal-title":"Behav Modif"},{"key":"10.1016\/j.psc.2020.08.010_bib32","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s10803-012-1671-0","article-title":"Subcategories of restricted and repetitive behaviors in children with autism spectrum disorders","volume":"43","author":"Bishop","year":"2013","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib33","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s10803-006-0123-0","article-title":"Comorbid psychiatric disorders in children with autism: interview development and rates of disorder","volume":"36","author":"Leyfer","year":"2006","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"5","key":"10.1016\/j.psc.2020.08.010_bib34","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1176\/ajp.152.5.772","article-title":"A\u00a0case-controlled study of repetitive thoughts and behaviour in adults with autistic disorder and obsessive-compulsive disorder","volume":"152","author":"McDougle","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib35","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1192\/bjp.186.6.525","article-title":"Obsessions and compulsions in Asperger syndrome and high-functioning autism","volume":"186","author":"Russell","year":"2005","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib36","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1007\/s10803-012-1531-y","article-title":"The Relationship between anxiety and repetitive behaviours in autism spectrum disorder","volume":"42","author":"Rodgers","year":"2012","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib37","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1159\/000111555","article-title":"Symptom overlap between autism spectrum disorders, generalized social anxiety disorder and obsessive-compulsive disorder in adults: a preliminary case-controlled study","volume":"41","author":"Cath","year":"2008","journal-title":"Psychopathology"},{"key":"10.1016\/j.psc.2020.08.010_bib38","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s10882-011-9247-z","article-title":"Phenomenology of comorbid autism spectrum and obsessive-compulsive disorders among children","volume":"23","author":"Lewin","year":"2011","journal-title":"J\u00a0Dev Phys Disabil"},{"key":"10.1016\/j.psc.2020.08.010_bib39","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.1007\/s10803-018-3645-3","article-title":"Presentation and correlates of hoarding behaviors in children with autism spectrum disorders and comorbid anxiety or obsessive-compulsive symptoms","volume":"48","author":"Buissonniere-Ariza","year":"2018","journal-title":"J\u00a0Autism Dev Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib40","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/aur.1461","article-title":"Obsessive-compulsive disorder in adults with high-functioning autism spectrum disorder: what does self-report with the OCI-R tell us?","volume":"8","author":"Cadman","year":"2015","journal-title":"Autism Res"},{"key":"10.1016\/j.psc.2020.08.010_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.rasd.2008.06.001","article-title":"Anxiety in children and adolescents with autism spectrum disorders","volume":"3","author":"MacNeil","year":"2009","journal-title":"Res Autism Spectr Disord"},{"issue":"4","key":"10.1016\/j.psc.2020.08.010_bib42","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/S0006-3223(00)00956-2","article-title":"Reactivity of Serotonin in the whole blood: relationship with drug response in obsessive-compulsive disorder","volume":"49","author":"Humble","year":"2001","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.psc.2020.08.010_bib43","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10882-017-9559-8","article-title":"Effectiveness of cognitive behavioral therapy for individuals with autism spectrum disorders and comorbid obsessive-compulsive disorder: a review of the research","volume":"30","author":"Kose","year":"2018","journal-title":"J\u00a0Dev Phys Disabil"},{"issue":"3","key":"10.1016\/j.psc.2020.08.010_bib44","first-page":"1","article-title":"Preliminary randomized trial of function-based cognitive-behavioral therapy to treat obsessive compulsive behavior in children with autism spectrum disorder","volume":"32","author":"Vause","year":"2015","journal-title":"Focus Autism Other Dev Disabl"},{"key":"10.1016\/j.psc.2020.08.010_bib45","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jocrd.2016.06.002","article-title":"Severe pediatric obsessive compulsive disorder and co-morbid autistic symptoms: effectiveness of cognitive behavioral therapy","volume":"10","author":"Wolters","year":"2016","journal-title":"J\u00a0Obsessive Compuls Relat Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib46","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10578-017-0724-1","article-title":"An initial case series of intensive cognitive-behavioral therapy for obsessive-compulsive disorder in adolescents with autism spectrum disorder","volume":"49","author":"Iniesta-Sepulveda","year":"2018","journal-title":"Child Psychiatry Hum Dev"},{"issue":"8","key":"10.1016\/j.psc.2020.08.010_bib47","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1002\/da.22053","article-title":"Cognitive behavior therapy for comorbid obsessive-compulsive disorder in high-functioning autism spectrum disorders: a randomized controlled trial","volume":"30","author":"Russell","year":"2013","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.psc.2020.08.010_bib48","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1177\/1362361311414066","article-title":"Feasibility of exposure response prevention to treat repetitive behaviors of children with autism and an intellectual disability: a brief report","volume":"17","author":"Boyd","year":"2013","journal-title":"Autism"},{"key":"10.1016\/j.psc.2020.08.010_bib49","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.psychres.2015.03.012","article-title":"Outcomes of cognitive behaviour therapy for obsessive-compulsive disorder in young people with and without autism spectrum disorders: a case controlled study","volume":"228","author":"Murray","year":"2015","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.psc.2020.08.010_bib50","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1207\/S15374424JCCP3001_3","article-title":"Cognitive-behavioral psychotherapy for pediatric obsessive-compulsive disorder","volume":"30","author":"March","year":"2001","journal-title":"J\u00a0Clin Child Psychol"},{"key":"10.1016\/j.psc.2020.08.010_bib51","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1002\/jclp.20082","article-title":"Cognitive-behavioral therapy for children who have obsessive-compulsive disorder","volume":"60","author":"Piacentini","year":"2004","journal-title":"J\u00a0Clin Psychol"},{"key":"10.1016\/j.psc.2020.08.010_bib52","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s10803-007-0457-2","article-title":"Brief Report: exposure and response prevention for obsessive compulsive disorder in a 12-year-old with autism","volume":"38","author":"Lehmkuhl","year":"2008","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"11","key":"10.1016\/j.psc.2020.08.010_bib53","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1002\/jclp.22396","article-title":"Modified cognitive behavior therapy for severe, treatment-resistant obsessive-compulsive disorder in an adolescent with autism spectrum disorder","volume":"72","author":"Krebs","year":"2016","journal-title":"J\u00a0Clin Psychol"},{"issue":"11","key":"10.1016\/j.psc.2020.08.010_bib54","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1097\/CHI.0b013e3181b76658","article-title":"A\u00a0placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder","volume":"48","author":"Marcus","year":"2009","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"issue":"6","key":"10.1016\/j.psc.2020.08.010_bib55","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1542\/peds.2008-3782","article-title":"Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder","volume":"124","author":"Owen","year":"2009","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.psc.2020.08.010_bib56","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1176\/appi.ajp.162.6.1142","article-title":"Risperidone for the core symptom domains of autism: results from the study by the autism network of the research unit on pediatric psychopharmacology","volume":"162","author":"McDougle","year":"2005","journal-title":"Am J Psychiatry"},{"issue":"6","key":"10.1016\/j.psc.2020.08.010_bib57","article-title":"Aripiprazole for autism spectrum disorders (ASD)","author":"Hirsch","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.psc.2020.08.010_bib58","article-title":"Risperidone for autism spectrum disorder","author":"Jesner","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"issue":"7","key":"10.1016\/j.psc.2020.08.010_bib59","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1001\/archpsyc.55.7.633","article-title":"A\u00a0double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders","volume":"55","author":"McDougle","year":"1998","journal-title":"Arch Gen Psychiatry"},{"issue":"16","key":"10.1016\/j.psc.2020.08.010_bib60","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1001\/jama.292.16.1969","article-title":"Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder","volume":"292","year":"2004","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.psc.2020.08.010_bib61","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S2215-0366(16)30069-4","article-title":"Pharmacological and psychotherapeutic interventions for management of obsessive-compulsive disorder in adults: a systematic review and network meta-analysis","volume":"3","author":"Skapinakis","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"6","key":"10.1016\/j.psc.2020.08.010_bib62","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1001\/archgenpsychiatry.2009.30","article-title":"Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior","volume":"66","author":"King","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib63","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1038\/sj.npp.1300627","article-title":"A\u00a0placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism","volume":"30","author":"Hollander","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psc.2020.08.010_bib64","article-title":"The SOFIA Study: negative multi-center study of low dose fluoxetine on repetitive behaviors in children and adolescents with autistic disorder","author":"Herscu","year":"2019","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"5","key":"10.1016\/j.psc.2020.08.010_bib65","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1023\/A:1005551523657","article-title":"Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors","volume":"30","author":"McDougle","year":"2000","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"11","key":"10.1016\/j.psc.2020.08.010_bib66","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1001\/archpsyc.1996.01830110037005","article-title":"A\u00a0double-blind, placebo controlled study of fluvoxamine in adults with autistic disorder","volume":"53","author":"McDougle","year":"1996","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib67","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1001\/archpsyc.1993.01820180039004","article-title":"A\u00a0double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder","volume":"50","author":"Gordon","year":"1993","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib68","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.wneu.2019.02.021","article-title":"Nucleus accumbens deep brain stimulation for obsessive-compulsive disorder and aggression in an autistic patient: a case report and hypothesis of the role of the nucleus accumbens in autism and comorbid symptoms","volume":"125","author":"Doshi","year":"2019","journal-title":"World Neurosurg"},{"key":"10.1016\/j.psc.2020.08.010_bib69","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s10803-008-0599-x","article-title":"Age-related differences in restricted repetitive behaviors in autism spectrum disorders","volume":"39","author":"Esbensen","year":"2009","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"9","key":"10.1016\/j.psc.2020.08.010_bib70","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyv047","article-title":"Antipsychotic augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: an update meta-analysis of double-blind, randomized placebo-controlled trials","volume":"18","author":"Dold","year":"2015","journal-title":"Int J Neuropsychopharmacol"},{"issue":"2","key":"10.1016\/j.psc.2020.08.010_bib71","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1586\/ern.12.160","article-title":"Augmentation strategies in obsessive-compulsive disorder","volume":"13","author":"Arumugham","year":"2013","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/j.psc.2020.08.010_bib72","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1017\/S0033291797006004","article-title":"Autism, affective, and other psychiatric disorders: patterns of familial aggregation","volume":"28","author":"Bolton","year":"1998","journal-title":"Psychol Med"},{"issue":"8","key":"10.1016\/j.psc.2020.08.010_bib73","first-page":"644","article-title":"Disorder-specific and shared brain Abnormalities during vigilance in autism and obsessive-compulsive disorder","volume":"2","author":"Carlisi","year":"2017","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"10.1016\/j.psc.2020.08.010_bib74","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3389\/fpsyt.2017.00143","article-title":"Cognitive-behavioral therapy for obsessive-compulsive disorder with and without autism spectrum disorder: gray matter differences associated with poor outcome","volume":"8","author":"Tsuchiyagaito","year":"2017","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib75","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.biopsych.2016.10.006","article-title":"Comparative multimodal meta-analysis of structural and functional brain abnormalities in autism spectrum disorder and obsessive-compulsive disorder","volume":"82","author":"Carlisi","year":"2017","journal-title":"Biol Psychiatry"},{"issue":"13","key":"10.1016\/j.psc.2020.08.010_bib76","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1017\/S0033291718003136","article-title":"Frontostriatal functional connectivity correlates with repetitive behavior across autism spectrum disorder and obsessive-compulsive disorder","volume":"49","author":"Akkermans","year":"2019","journal-title":"Psychol Med"},{"key":"10.1016\/j.psc.2020.08.010_bib77","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.euroneuro.2017.11.010","article-title":"Striatal structure and its association with N-Acetylaspartate and glutamate in autism spectrum disorder and obsessive compulsive disorder","volume":"28","author":"Naaijen","year":"2018","journal-title":"Eur Neuropsychopharmacol"},{"issue":"1","key":"10.1016\/j.psc.2020.08.010_bib78","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1038\/tp.2011.65","article-title":"Age-related change in brain metabolite abnormalities in autism: a meta-analysis of proton magnetic resonance spectroscopy studies","volume":"2","author":"Aoki","year":"2012","journal-title":"Transl Psychiatry"},{"issue":"8","key":"10.1016\/j.psc.2020.08.010_bib79","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1038\/tp.2012.78","article-title":"Reduction of N-acetylaspartate in the medial prefrontal cortex correlated with symptom severity in obsessive-compulsive disorder: meta-analyses of H-MRS studies","volume":"2","author":"Aoki","year":"2012","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib80","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1038\/npp.2016.260","article-title":"Fronto-striatal glutamate in autism spectrum disorder and obsessive compulsive disorder","volume":"42","author":"Naaijen","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psc.2020.08.010_bib81","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1503\/jpn.110109","article-title":"Association between the NMDA glutamate receptor GRIN2B gene and obsessive-compulsive disorder","volume":"37","author":"Alonso","year":"2012","journal-title":"J\u00a0Psychiatry Neurosci"},{"key":"10.1016\/j.psc.2020.08.010_bib82","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1007\/s10803-010-0958-2","article-title":"Comorbid psychiatric disorders associated with Asperger syndrome\/high-functioning autism: a community and clinic-based study","volume":"40","author":"Mattila","year":"2010","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"1","key":"10.1016\/j.psc.2020.08.010_bib83","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.rasd.2010.03.006","article-title":"Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders","volume":"5","author":"Mazefsky","year":"2011","journal-title":"Res Autism Spectr Disord"},{"key":"10.1016\/j.psc.2020.08.010_bib84","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/aur.108","article-title":"Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics","volume":"2","author":"Jacob","year":"2009","journal-title":"Autism Res"},{"key":"10.1016\/j.psc.2020.08.010_bib85","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/sj.mp.4001365","article-title":"Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype","volume":"8","author":"Ozaki","year":"2003","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib86","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1002\/ajmg.b.30699","article-title":"Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review","volume":"147B","author":"Bloch","year":"2008","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"6","key":"10.1016\/j.psc.2020.08.010_bib87","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1002\/ajmg.a.38171","article-title":"De Novo unbalanced translocation (4p duplication\/8p deletion) in a patient with autism, OCD, and overgrowth syndrome","volume":"173","author":"Sagar","year":"2017","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.psc.2020.08.010_bib88","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1086\/338241","article-title":"Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families","volume":"70","author":"Alarcon","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.psc.2020.08.010_bib89","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/sj.mp.4001465","article-title":"Linkage analysis for autism in a subset families with obsessive-compulsive behaviors: evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19","volume":"9","author":"Buxbaum","year":"2004","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib90","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1086\/367846","article-title":"Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes","volume":"72","author":"Shao","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.psc.2020.08.010_bib91","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2018.00216","article-title":"White matter features associated with autistic traits in obsessive-compulsive disorder","volume":"9","author":"Kuno","year":"2018","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib92","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1177\/1362361309335717","article-title":"Which DSM-IV-TR criteria best differentiate high-functioning autism spectrum disorder from ADHD and anxiety disorders in older children?","volume":"13","author":"Hartley","year":"2009","journal-title":"Autism"},{"key":"10.1016\/j.psc.2020.08.010_bib93","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/s00787-002-0279-x","article-title":"Repetitive behaviors in autistic disorder","volume":"11","author":"Militerni","year":"2002","journal-title":"Eur Child Adolesc Psychiatry"},{"issue":"5","key":"10.1016\/j.psc.2020.08.010_bib94","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1177\/1362361307079606","article-title":"The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning spectrum","volume":"11","author":"South","year":"2007","journal-title":"Autism"},{"key":"10.1016\/j.psc.2020.08.010_bib95","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s10803-005-5035-x","article-title":"Examining the relationship between executive functions and the restricted, repetitive symptoms of autistic disorder","volume":"35","author":"Lopez","year":"2005","journal-title":"J\u00a0Autism Dev Disord"},{"issue":"5","key":"10.1016\/j.psc.2020.08.010_bib96","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1001\/archpsyc.55.5.415","article-title":"Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls","volume":"55","author":"Purcell","year":"1998","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.psc.2020.08.010_bib97","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1177\/1362361303007002003","article-title":"Cognitive-behavioral treatment of obsessive compulsive disorder in a child with Asperger syndrome","volume":"7","author":"Reaven","year":"2003","journal-title":"Autism"},{"issue":"5","key":"10.1016\/j.psc.2020.08.010_bib98","first-page":"600","article-title":"Increasing knowledge about obsessive compulsive disorder and support for parents and schools: evaluation of initiatives","volume":"75","author":"Jassi","year":"2015","journal-title":"Health Education"}],"container-title":["Psychiatric Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0193953X20300575?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0193953X20300575?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T01:40:26Z","timestamp":1759282826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0193953X20300575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":98,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S0193953X20300575"],"URL":"https:\/\/doi.org\/10.1016\/j.psc.2020.08.010","relation":{},"ISSN":["0193-953X"],"issn-type":[{"value":"0193-953X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Obsessive\u2013Compulsive Disorder in Autism Spectrum Disorder Across the Lifespan","name":"articletitle","label":"Article Title"},{"value":"Psychiatric Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psc.2020.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}