{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:02:34Z","timestamp":1789858954713,"version":"4.0.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychiatry Research: Neuroimaging"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.pscychresns.2026.112332","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:59:27Z","timestamp":1789397967000},"page":"112332","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Default mode network connectivity associated with rumination in major depressive disorder: A systematic review of resting-state fMRI studies"],"prefix":"10.1016","volume":"364","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2697-2807","authenticated-orcid":false,"given":"Sahar","family":"Riaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9857-0611","authenticated-orcid":false,"given":"Orla","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8291-9155","authenticated-orcid":false,"given":"Ronan","family":"Fleury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7070-5469","authenticated-orcid":false,"given":"Darren W","family":"Roddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9513-6036","authenticated-orcid":false,"given":"Michael","family":"Connaughton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.pscychresns.2026.112332_bib0001","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.neuron.2010.02.005","article-title":"Functional-anatomic fractionation of the brain's default network","volume":"65","author":"Andrews-Hanna","year":"2010","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.pscychresns.2026.112332_bib0002","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nrn2575","article-title":"Complex brain networks: graph theoretical analysis of structural and functional systems","volume":"10","author":"Bullmore","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.pscychresns.2026.112332_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117185","article-title":"The subsystem mechanism of default mode network underlying rumination: a reproducible neuroimaging study","volume":"221","author":"Chen","year":"2020","journal-title":"Neuroimage"},{"issue":"21","key":"10.1016\/j.pscychresns.2026.112332_bib0004","doi-asserted-by":"crossref","first-page":"8719","DOI":"10.1073\/pnas.0900234106","article-title":"Experience sampling during fMRI reveals default network and executive system contributions to mind wandering","volume":"106","author":"Christoff","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"10.1016\/j.pscychresns.2026.112332_bib0005","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.biopsych.2013.05.036","article-title":"Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents [Article]","volume":"74","author":"Connolly","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"9","key":"10.1016\/j.pscychresns.2026.112332_bib0006","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nrn2201","article-title":"Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging","volume":"8","author":"Fox","year":"2007","journal-title":"Nat Rev Neurosci"},{"issue":"4","key":"10.1016\/j.pscychresns.2026.112332_bib0007","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.biopsych.2015.02.020","article-title":"Depressive Rumination, the Default-Mode Network, and the Dark Matter of Clinical Neuroscience","volume":"78","author":"Hamilton","year":"2015","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.pscychresns.2026.112332_bib0008","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.biopsych.2011.02.003","article-title":"Default-mode and task-positive network activity in major depressive disorder: implications for adaptive and maladaptive rumination","volume":"70","author":"Hamilton","year":"2011","journal-title":"Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.pscychresns.2026.112332_bib0009","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/j.2051-5545.2010.tb00298.x","article-title":"Pathophysiology of depression: do we have any solid evidence of interest to clinicians?","volume":"9","author":"Hasler","year":"2010","journal-title":"World Psychiatry"},{"issue":"1","key":"10.1016\/j.pscychresns.2026.112332_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tins.2010.10.004","article-title":"Stuck in a rut: rethinking depression and its treatment","volume":"34","author":"Holtzheimer","year":"2011","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0011","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.neuroimage.2013.05.079","article-title":"Dynamic functional connectivity: promise, issues, and interpretations","volume":"80","author":"Hutchison","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0012","article-title":"Neural correlates of rumination in major depressive disorder: a brain network analysis","volume":"25","author":"Jacob","year":"2020","journal-title":"NeuroImage: Clin."},{"key":"10.1016\/j.pscychresns.2026.112332_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.102142","article-title":"Neural correlates of rumination in major depressive disorder: a brain network analysis","volume":"25","author":"Jacob","year":"2020","journal-title":"Neuroimage Clin"},{"issue":"7","key":"10.1016\/j.pscychresns.2026.112332_bib0014","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1038\/npp.2015.352","article-title":"Dynamic Resting-State Functional Connectivity in Major Depression","volume":"41","author":"Kaiser","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0015","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.neuroimage.2014.06.044","article-title":"Dynamic functional connectivity of the default mode network tracks daydreaming","volume":"100","author":"Kucyi","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0016","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jad.2023.05.074","article-title":"Trait- and state-like co-activation pattern dynamics in current and remitted major depressive disorder","volume":"337","author":"Liu","year":"2023","journal-title":"J Affect Disord"},{"issue":"10","key":"10.1016\/j.pscychresns.2026.112332_bib0017","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-049798","article-title":"Resting-state functional reorganisation in Alzheimer's disease and amnestic mild cognitive impairment: protocol for a systematic review and meta-analysis","volume":"11","author":"Lyu","year":"2021","journal-title":"BMJ Open"},{"issue":"9","key":"10.1016\/j.pscychresns.2026.112332_bib0018","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1080\/13803395.2024.2315312","article-title":"Functional connectivity in rumination: a systematic review of magnetic resonance imaging studies","volume":"45","author":"Misir","year":"2023","journal-title":"J Clin Exp Neuropsychol"},{"issue":"1","key":"10.1016\/j.pscychresns.2026.112332_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0020","unstructured":"National Heart, L., & Institute, B. (2014). Quality assessment tool for observational cohort and cross-sectional studies. In."},{"issue":"5","key":"10.1016\/j.pscychresns.2026.112332_bib0021","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1745-6924.2008.00088.x","article-title":"Rethinking rumination","volume":"3","author":"Nolen-Hoeksema","year":"2008","journal-title":"Perspect. Psychol. Sci."},{"issue":"9","key":"10.1016\/j.pscychresns.2026.112332_bib0022","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.recesp.2021.06.016","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"74","author":"Page","year":"2021","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"issue":"4","key":"10.1016\/j.pscychresns.2026.112332_bib0023","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/jon.13011","article-title":"Functional MRI in major depressive disorder: a review of findings, limitations, and future prospects","volume":"32","author":"Pilmeyer","year":"2022","journal-title":"J. Neuroimaging"},{"issue":"3","key":"10.1016\/j.pscychresns.2026.112332_bib0024","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: uses and interpretations","volume":"52","author":"Rubinov","year":"2010","journal-title":"Neuroimage"},{"issue":"5","key":"10.1016\/j.pscychresns.2026.112332_bib0025","doi-asserted-by":"crossref","first-page":"884","DOI":"10.3758\/s13415-018-0611-7","article-title":"Functional connectivity of reflective and brooding rumination in depressed and healthy women","volume":"18","author":"Satyshur","year":"2018","journal-title":"Cogn Affect Behav Neurosci"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0026","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1472-6947-7-16","article-title":"Utilization of the PICO framework to improve searching PubMed for clinical questions","volume":"7","author":"Schardt","year":"2007","journal-title":"BMC Med Inf. Decis Mak"},{"issue":"7","key":"10.1016\/j.pscychresns.2026.112332_bib0027","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1038\/npp.2015.8","article-title":"Prefrontal thinning affects functional connectivity and regional homogeneity of the anterior cingulate cortex in depression","volume":"40","author":"Spati","year":"2015","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.pscychresns.2026.112332_bib0028","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.euroneuro.2010.03.008","article-title":"Exploring the brain network: a review on resting-state fMRI functional connectivity","volume":"20","author":"van den Heuvel","year":"2010","journal-title":"Eur Neuropsychopharmacol"},{"issue":"4","key":"10.1016\/j.pscychresns.2026.112332_bib0029","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.40","article-title":"Instability of default mode network connectivity in major depression: a two-sample confirmation study","volume":"7","author":"Wise","year":"2017","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109819","article-title":"Rumination network dysfunction in major depression: a brain connectome study","volume":"98","author":"Zhang","year":"2020","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109819","article-title":"Rumination network dysfunction in major depression: a brain connectome study","volume":"98","author":"Zhang","year":"2020","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0032","article-title":"Aberrant functional metastability and structural connectivity are associated with rumination in individuals with major depressive disorder","volume":"33","author":"Zhang","year":"2022","journal-title":"NeuroImage: Clin."},{"key":"10.1016\/j.pscychresns.2026.112332_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102916","article-title":"Aberrant functional metastability and structural connectivity are associated with rumination in individuals with major depressive disorder","volume":"33","author":"Zhang","year":"2022","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0034","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291725000303","article-title":"Resting-state network alterations in depression: a comprehensive meta-analysis of functional connectivity","volume":"55","author":"Zhang","year":"2025","journal-title":"Psychol Med"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116287","article-title":"Rumination and the default mode network: meta-analysis of brain imaging studies and implications for depression","volume":"206","author":"Zhou","year":"2020","journal-title":"Neuroimage"},{"issue":"7","key":"10.1016\/j.pscychresns.2026.112332_bib0036","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.biopsych.2011.10.035","article-title":"Evidence of a dissociation pattern in resting-state default mode network connectivity in first-episode, treatment-naive major depression patients","volume":"71","author":"Zhu","year":"2012","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0037","article-title":"Rumination and Default Mode Network Subsystems Connectivity in First-episode, Drug-Naive Young Patients with Major Depressive Disorder","volume":"7","author":"Zhu","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.pscychresns.2026.112332_bib0038","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jad.2023.04.082","article-title":"Habenula functional connectivity variability increases with disease severity in individuals with major depression","volume":"333","author":"Zhu","year":"2023","journal-title":"J Affect Disord"},{"issue":"21","key":"10.1016\/j.pscychresns.2026.112332_fur1","doi-asserted-by":"crossref","first-page":"8719","DOI":"10.1073\/pnas.0900234106","article-title":"Experience sampling during fMRI reveals default network and executive system contributions to mind wandering","volume":"106","author":"Christoff","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.pscychresns.2026.112332_fur2","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.neuroimage.2014.06.044","article-title":"Dynamic functional connectivity of the default mode network tracks daydreaming","volume":"100","author":"Kucyi","year":"2014","journal-title":"Neuroimage"}],"container-title":["Psychiatry Research: Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925492726001976?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925492726001976?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T22:57:42Z","timestamp":1789858662000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925492726001976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":40,"alternative-id":["S0925492726001976"],"URL":"https:\/\/doi.org\/10.1016\/j.pscychresns.2026.112332","relation":{},"ISSN":["0925-4927"],"issn-type":[{"value":"0925-4927","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Default mode network connectivity associated with rumination in major depressive disorder: A systematic review of resting-state fMRI studies","name":"articletitle","label":"Article Title"},{"value":"Psychiatry Research: Neuroimaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pscychresns.2026.112332","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"112332"}}