{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:47:59Z","timestamp":1786996079599,"version":"build-2736575974"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003668","name":"Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014189","name":"Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003624","name":"Ministry of Agriculture, Food and Rural Affairs","doi-asserted-by":"publisher","award":["317010-3"],"award-info":[{"award-number":["317010-3"]}],"id":[{"id":"10.13039\/501100003624","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.psj.2020.07.021","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T20:44:36Z","timestamp":1596833076000},"page":"100528","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy of a novel avian metapneumovirus live vaccine candidate based on vaccination route and age"],"prefix":"10.1016","volume":"100","author":[{"given":"Ha-Na","family":"Youn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Yong","family":"Noh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong-Seob","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Sun","family":"Ju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dam-Hee","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-Ye","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-jik","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Hye","family":"Go","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Seon","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2020.07.021_bib1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.rvsc.2014.11.004","article-title":"Immune responses and interactions following simultaneous application of live Newcastle disease, infectious bronchitis and avian metapneumovirus vaccines in specific-pathogen-free chicks","volume":"98","author":"Awad","year":"2015","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2020.07.021_bib2","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.vaccine.2009.10.149","article-title":"Field avian metapneumovirus evolution avoiding vaccine induced immunity","volume":"28","author":"Catelli","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2020.07.021_bib3","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.vetmic.2010.04.014","article-title":"Avian metapneumovirus (AMPV) attachment protein involvement in probable virus evolution concurrent with mass live vaccine introduction","volume":"146","author":"Cecchinato","year":"2010","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2020.07.021_bib4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.vetimm.2005.06.012","article-title":"Protection by recombinant viral proteins against a respiratory challenge with virulent avian metapneumovirus","volume":"108","author":"Chary","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2020.07.021_bib5","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1637\/9382-042710-Reg.1","article-title":"Diagnostic utility of egg yolk for the detection of avian metapneumovirus antibodies in laying hens","volume":"54","author":"Choi","year":"2010","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2020.07.021_bib6","doi-asserted-by":"crossref","first-page":"9493","DOI":"10.1016\/j.vaccine.2011.10.024","article-title":"Avian metapneumovirus M2:2 protein inhibits replication in Vero cells: modification facilitates live vaccine development","volume":"29","author":"Clubbe","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2020.07.021_bib7","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1080\/03079459994407","article-title":"Preliminary antigenic characterization of an avian pneumovirus isolated from commercial turkeys in Colorado, USA","volume":"28","author":"Cook","year":"2010","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib8","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/03079459608419138","article-title":"An experimental Turkey rhinotracheitis (TRT) infection in breeding turkeys and the prevention of its clinical effects using live-attenuated and inactivated TRT vaccines","volume":"25","author":"Cook","year":"1996","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib9","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1016\/j.vaccine.2015.03.092","article-title":"Subpopulations in aMPV vaccines are unlikely to be the only cause of reversion to virulence","volume":"33","author":"Franzo","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2020.07.021_bib10","doi-asserted-by":"crossref","first-page":"3944","DOI":"10.1016\/j.vaccine.2010.03.065","article-title":"Vaccination of commercial broiler chicks against avian metapneumovirus infection: a comparison of drinking-water, spray and oculo-oral delivery methods","volume":"28","author":"Ganapathy","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2020.07.021_bib11","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/03079450500178824","article-title":"Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens","volume":"34","author":"Ganapathy","year":"2005","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib12","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/03079450701460781","article-title":"Protection in specific pathogen free chickens with live avian metapneumovirus and Newcastle disease virus vaccines applied singly or in combination","volume":"36","author":"Ganapathy","year":"2007","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib13","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1637\/0005-2086(2007)51[733:VOCWLA]2.0.CO;2","article-title":"Vaccination of chicks with live attenuated subtype B avian metapneumovirus vaccines: protection against challenge and immune responses can be unrelated to vaccine dose","volume":"51","author":"Ganapathy","year":"2007","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2020.07.021_bib14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1080\/03079450601007518","article-title":"Interaction between a live avian pneumovirus vaccine and two different Newcastle disease virus vaccines in broiler chickens with maternal antibodies to Newcastle disease virus","volume":"35","author":"Ganapathy","year":"2006","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/0034-5288(92)90081-C","article-title":"Effect of cyclophosphamide immunosuppression on the immunity of turkeys to viral rhinotracheitis","volume":"53","author":"Jones","year":"1992","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2020.07.021_bib16","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3382\/ps\/pev377","article-title":"Development of a highly immunogenic Newcastle disease virus chicken vaccine strain of duck origin","volume":"95","author":"Kim","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.07.021_bib17","series-title":"The investigation of sero-prevalence and occurrence of SHS from broiler breeder in Korea. Proceeding","author":"Kim","year":"1992"},{"key":"10.1016\/j.psj.2020.07.021_bib18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4142\/jvs.2010.11.1.59","article-title":"Isolation and characterization of avian metapneumovirus from chickens in Korea","volume":"11","author":"Kwon","year":"2010","journal-title":"J. Vet. Sci."},{"key":"10.1016\/j.psj.2020.07.021_bib19","series-title":"Studies on Detection of turkey Rhinotracheitis Virus Using Monoclonal Antibody and Polymerase Chain Reaction. Master","author":"Lee","year":"1995"},{"key":"10.1016\/j.psj.2020.07.021_bib20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.5536\/KJPS.2010.37.4.361","article-title":"Serological Survey for the major viral diseases in the layers","volume":"37","author":"Lee","year":"2010","journal-title":"Korean J. Poult. Sci."},{"key":"10.1016\/j.psj.2020.07.021_bib21","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.virusres.2007.03.029","article-title":"Genetic characterization of avian metapneumovirus subtype C isolated from pheasants in a live bird market","volume":"128","author":"Lee","year":"2007","journal-title":"Virus Res."},{"key":"10.1016\/j.psj.2020.07.021_bib22","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/03079457.2011.607428","article-title":"A Turkey rhinotracheitis outbreak caused by the environmental spread of a vaccine-derived avian metapneumovirus","volume":"40","author":"Lupini","year":"2011","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib23","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1637\/8928-051909-Reg.1","article-title":"Immunogenicity and safety of Queensland V4 and Ulster 2C strains of Newcastle disease virus given to maternally immune, newly hatched chickens by nebulization","volume":"54","author":"Mazija","year":"2010","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2020.07.021_bib24","doi-asserted-by":"crossref","first-page":"968","DOI":"10.2307\/1592354","article-title":"Failure of maternal antibodies to protect young Turkey poults against challenge with Turkey rhinotracheitis virus","volume":"41","author":"Naylor","year":"1997","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2020.07.021_bib25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/03079450500059214","article-title":"Growth of vaccine strains of avian pneumovirus in different cell lines","volume":"34","author":"Patnayak","year":"2005","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib26","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.virusres.2016.04.014","article-title":"Immunization with avian metapneumovirus harboring chicken Fc induces higher immune responses","volume":"220","author":"Paudel","year":"2016","journal-title":"Virus Res."},{"key":"10.1016\/j.psj.2020.07.021_bib27","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/03079450903349204","article-title":"Investigations on the protective role of passively transferred antibodies against avian metapneumovirus infection in turkeys","volume":"38","author":"Rubbenstroth","year":"2009","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.07.021_bib28","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12917-015-0345-5","article-title":"Development of vaccine-induced immunity against TRT in turkeys depends remarkably on the level of maternal antibodies and the age of birds on the day of vaccination","volume":"11","author":"Smialek","year":"2015","journal-title":"BMC Vet. Res."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579120304909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579120304909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:35:14Z","timestamp":1758494114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579120304909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S0032579120304909"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2020.07.021","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of a novel avian metapneumovirus live vaccine candidate based on vaccination route and age","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2020.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"100528"}}