{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:39:31Z","timestamp":1787063971367,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17K19323"],"award-info":[{"award-number":["17K19323"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.psj.2020.08.071","type":"journal-article","created":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T11:01:11Z","timestamp":1599908471000},"page":"7092-7100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effects of avian infectious bronchitis with Newcastle disease and Marek's disease vaccinations on the expression of toll-like receptors and avian \u03b2-defensins in the kidneys of broiler chicks"],"prefix":"10.1016","volume":"99","author":[{"given":"Masahiro","family":"Shimizu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Nii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Isobe,","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukinori","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2020.08.071_bib1","doi-asserted-by":"crossref","first-page":"979","DOI":"10.3382\/ps.2007-00283","article-title":"Expression of avian \u03b2-defensins in the oviduct and effects of lipopolysaccharide on their expression in the vagina of hens","volume":"87","author":"Abdel Mageed","year":"2008","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib2","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1530\/REP-09-0181","article-title":"Immunolocalization of avian \u03b2-defensins in the hen oviduct and their changes in the uterus during eggshell formation","volume":"138","author":"Abdel Mageed","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.psj.2020.08.071_bib3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1155\/2016\/4621659","article-title":"Pathogenesis and diagnostic approaches of avian infectious bronchitis","volume":"2016","author":"Bande","year":"2016","journal-title":"Adv. Virol."},{"key":"10.1016\/j.psj.2020.08.071_bib4","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S0034-5288(18)30685-4","article-title":"Observations on the pathogenesis of experimental Salmonella typhimurium infection in chickens","volume":"42","author":"Barrow","year":"1987","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1080\/03079459608419174","article-title":"Cytopathology of chick renal epithelial cells experimentally infected with avian infectious bronchitis virus","volume":"25","author":"Chen","year":"1996","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2020.08.071_bib6","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1297-9716-45-36","article-title":"Marek's disease virus and skin interactions","volume":"45","author":"Couteaudier","year":"2014","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2020.08.071_bib7","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.3382\/ps\/pew073","article-title":"Isolation and pathogenic analysis of virulent Marek\u2019s disease virus field strain in China","volume":"95","author":"Cui","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib8","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.dci.2013.04.019","article-title":"Avian host defense peptides","volume":"41","author":"Cuperus","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.psj.2020.08.071_bib9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.smim.2018.06.002","article-title":"Non-specific effects of vaccines: current evidence and potential implications","volume":"39","author":"De Bree","year":"2018","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.psj.2020.08.071_bib10","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/0300985816655852","article-title":"Pathogenesis of renal lesions in chickens after experimental infection with 9a5b newcastle disease virus mutant isolate","volume":"54","author":"El-Bahrawy","year":"2017","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.psj.2020.08.071_bib11","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1637\/10227-043012-Review.1","article-title":"Review of infectious bronchitis virus around the world","volume":"56","author":"Jackwood","year":"2012","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2020.08.071_bib12","doi-asserted-by":"crossref","first-page":"5127","DOI":"10.3382\/ps\/pez214","article-title":"Effects of the routine multiple vaccinations on the expression of innate immune molecules and induction of histone modification in ovarian cells of layer chicks","volume":"98","author":"Kang","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib13","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2020.08.071_bib14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.vetimm.2018.06.007","article-title":"Gene expression of AvBD6-10 in broiler chickens is independent of AvBD6, 9, and 10 peptide potency","volume":"202","author":"Mowbray","year":"2018","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2020.08.071_bib15","doi-asserted-by":"crossref","first-page":"aaf1098","DOI":"10.1126\/science.aaf1098","article-title":"Trained immunity: a program of innate immune memory in health and disease","volume":"352","author":"Netea","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.psj.2020.08.071_bib16","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0378-1135(97)00163-6","article-title":"Virulence mechanisms of avian fimbriated Escherichia coli in experimentally inoculated chickens","volume":"58","author":"Pourbakhsh","year":"1997","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2020.08.071_bib17","doi-asserted-by":"crossref","first-page":"280","DOI":"10.2141\/jpsa.0180022","article-title":"Changes in the expression of avian \u03b2-defensins (AvBDs) and proinflammatory cytokines and localization of AvBD2 in the intestine of broiler embryos and chicks during growth","volume":"55","author":"Terada","year":"2018","journal-title":"J. Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib18","doi-asserted-by":"crossref","first-page":"310","DOI":"10.2141\/jpsa.0190098","article-title":"Effects of probiotics Lactobacillus reuteri and Clostridium butyricum on the expression of Toll-like receptors, pro- and anti-inflammatory cytokines, and antimicrobial peptides in broiler chick intestine","volume":"57","author":"Terada","year":"2020","journal-title":"J. Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib19","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.1016\/j.psj.2020.03.016","article-title":"Effect of antibiotic treatment on microbial composition and expression of antimicrobial peptides and cytokines in the chick cecum","volume":"99","author":"Terada","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib20","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3382\/ps\/peu021","article-title":"Avian \u03b2-defensins expression for the innate immune system in hen reproductive organs","volume":"294","author":"Yoshimura","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2020.08.071_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-981-10-3975-1_3","article-title":"Female reproductive system and immunology","volume":"1001","author":"Yoshimura","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.psj.2020.08.071_bib22","doi-asserted-by":"crossref","first-page":"9011","DOI":"10.1007\/s00253-015-6786-8","article-title":"Differential modulation of avian \u03b2-defensin and Toll-like receptor expression in chickens infected with infectious bronchitis virus","volume":"99","author":"Xu","year":"2015","journal-title":"Appl. Microbiol. Biot."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579120306180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579120306180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:32:44Z","timestamp":1758493964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579120306180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S0032579120306180"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2020.08.071","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of avian infectious bronchitis with Newcastle disease and Marek's disease vaccinations on the expression of toll-like receptors and avian \u03b2-defensins in the kidneys of broiler chicks","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2020.08.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}]}}