{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T02:28:29Z","timestamp":1766888909793,"version":"3.44.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T00:00:00Z","timestamp":1617840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.psj.2021.101199","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T20:33:01Z","timestamp":1618950781000},"page":"101199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of serum antioxidative status, immune status and intestinal condition of Linwu duck challenged by lipopolysaccharide with various dosages and replications"],"prefix":"10.1016","volume":"100","author":[{"given":"Yang","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guitao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingguo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengli","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuzhong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2021.101199_bib0001","first-page":"1","article-title":"The effects of superoxide dismutase-rich melon pulp concentrate on inflammation, antioxidant status and growth performance of challenged post-weaning piglets","volume":"13","author":"Ahasan","year":"2018","journal-title":"Animal"},{"key":"10.1016\/j.psj.2021.101199_bib0002","doi-asserted-by":"crossref","first-page":"912","DOI":"10.3390\/toxins5050912","article-title":"The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity","volume":"5","author":"Awad","year":"2013","journal-title":"Toxins"},{"key":"10.1016\/j.psj.2021.101199_bib0003","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/jcp.25435","article-title":"LPS induces hyper-permeability of intestinal epithelial cells","volume":"232","author":"Bein","year":"2017","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.psj.2021.101199_bib0004","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.intimp.2012.11.021","article-title":"The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-\u03baB signaling through TLR4 in macrophages","volume":"15","author":"Byun","year":"2013","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.psj.2021.101199_bib0005","doi-asserted-by":"crossref","first-page":"e53221","DOI":"10.1371\/journal.pone.0053221","article-title":"Endotoxin tolerance variation over 24 h during porcine endotoxemia: association with changes in circulation and organ dysfunction","volume":"8","author":"Castegren","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2021.101199_bib0006","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.rvsc.2020.09.005","article-title":"Effects of different doses lipopolysaccharides on the mucosal barrier in mouse intestine - ScienceDirect","volume":"133","author":"Chao","year":"2020","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0007","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.psj.2020.10.070","article-title":"Bacillus subtilis-fermented products ameliorate the growth performance and alter cecal microbiota community in broilers under lipopolysaccharide challenge","volume":"100","author":"Chen","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0008","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1017\/S0007114518000740","article-title":"Dietary l-threonine supplementation attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage of broiler chickens at an early age","volume":"119","author":"Chen","year":"2018","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.psj.2021.101199_bib0009","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/00071660802538632","article-title":"Managing gut health through nutrition","volume":"50","author":"Choct","year":"2009","journal-title":"Br. Poult."},{"key":"10.1016\/j.psj.2021.101199_bib0010","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3390\/ani10020347","article-title":"Effect of carotenoids, oligosaccharides and anthocyanins on growth performance, immunological parameters and intestinal morphology in broiler chickens challenged with lipopolysaccharide","volume":"10","author":"Csernus","year":"2020","journal-title":"Animals"},{"key":"10.1016\/j.psj.2021.101199_bib0011","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/femsre\/fuz002","article-title":"Lipopolysaccharide structures of Gram-negative populations in the gut microbiota and effects on host interactions","volume":"43","author":"Flaviana","year":"2019","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.psj.2021.101199_bib0012","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/jpn.12579","article-title":"Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals","volume":"101","author":"Gessner","year":"2016","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.psj.2021.101199_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.550769","article-title":"HDAC3 mediates the inflammatory response and LPS tolerance in human monocytes and macrophages","volume":"11","author":"Ghiboub","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2021.101199_bib0014","first-page":"226","article-title":"Dietary supplementation with tributyrin prevented weaned pigs from growth retardation and lethal infection via modulation of inflammatory cytokines production, ileal expression, and intestinal acetate fermentation","volume":"95","author":"Gu","year":"2017","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0015","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skaa311","article-title":"Dietary taurine supplementation attenuates lipopolysaccharide-induced inflammatory responses and oxidative stress of broiler chickens at an early age","volume":"98","author":"Han","year":"2020","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0016","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jneuroim.2010.12.009","article-title":"The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression","volume":"233","author":"Hollis","year":"2011","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.psj.2021.101199_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2020.155408","article-title":"Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities","volume":"139","author":"Kamdi","year":"2021","journal-title":"Cytokine"},{"key":"10.1016\/j.psj.2021.101199_bib0018","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1093\/jn\/117.9.1629","article-title":"Immunologically mediated growth depression in chicks: influence of feed intake, corticosterone and interleukin-1","volume":"117","author":"Klasing","year":"1987","journal-title":"J. Nutr."},{"key":"10.1016\/j.psj.2021.101199_bib0019","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.rvsc.2020.09.005","article-title":"Effects of different doses lipopolysaccharides on the mucosal barrier in mouse intestine","volume":"133","author":"Li","year":"2020","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0020","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.psj.2020.10.021","article-title":"Effects of Astragalus polysaccharides on intestinal morphology and intestinal immune cells of Muscovy ducklings infected with Muscovy duck reovirus","volume":"100","author":"Liao","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0021","doi-asserted-by":"crossref","first-page":"992","DOI":"10.3109\/19401736.2014.926520","article-title":"The complete mitochondrial genome of the Linwu duck","volume":"27","author":"Lin","year":"2016","journal-title":"Mitochondrial DNA"},{"key":"10.1016\/j.psj.2021.101199_bib0022","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/mi.2013.109","article-title":"REG3 gamma-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum","volume":"7","author":"Loonen","year":"2014","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.psj.2021.101199_bib0023","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1242\/jeb.056499","article-title":"The development of endotoxin tolerance, and the role of hypothalamo-pituitary-adrenal function and glucocorticoids in Pekin ducks","volume":"214","author":"Marais","year":"2011","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.psj.2021.101199_bib41","unstructured":"National Research Council. 1994. Nutrient Requirements of Poultry. 9th rev. ed. Natl. Acad. Press, Washington, DC."},{"key":"10.1016\/j.psj.2021.101199_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2019.102411","article-title":"Splenic anti-inflammatory reflex in immune tolerance","volume":"85","author":"Nogueira","year":"2019","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.psj.2021.101199_bib0025","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.fsi.2008.12.004","article-title":"LPS response and tolerance in the zebrafish (Danio rerio)","volume":"26","author":"Novoa","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.psj.2021.101199_bib0026","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.cmet.2014.12.005","article-title":"Pyruvate kinase M2 regulates Hif-1\u03b1 activity and IL-1\u03b2 induction and is a critical determinant of the warburg effect in LPS-activated macrophages","volume":"21","author":"Palsson-Mcdermott","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.psj.2021.101199_bib0027","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S1016-8478(23)13191-8","article-title":"Mechanisms underlying the effects of LPS and activation-induced cytidine deaminase on IgA isotype expression","volume":"19","author":"Park","year":"2005","journal-title":"Mol. Cells"},{"key":"10.1016\/j.psj.2021.101199_bib0028","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.3382\/ps\/pex244","article-title":"Effects of hydroxychloride and sulfate form of zinc and manganese supplementation on superoxide dismutase activity and immune responses post lipopolysaccharide challenge in poultry fed marginally lower doses of zinc and manganese","volume":"96","author":"Perez","year":"2017","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0029","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev.bi.59.070190.001021","article-title":"Biochemistry of endotoxins","volume":"59","author":"Raetz","year":"1990","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.psj.2021.101199_bib0030","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.3390\/ijms18071431","article-title":"LPS-Induced low-grade inflammation increases hypothalamic JNK expression and causes central insulin resistance irrespective of body weight changes","volume":"18","author":"Rorato","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0031","doi-asserted-by":"crossref","first-page":"e13373","DOI":"10.1111\/apha.13373","article-title":"Increased hypothalamic hydrogen sulphide contributes to endotoxin tolerance by down-modulating PGE production","volume":"228","author":"Santos","year":"2020","journal-title":"Acta Physiologica"},{"key":"10.1016\/j.psj.2021.101199_bib0032","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1079\/BJN19950121","article-title":"Effect of dietary protein concentration on responses to Escherichia coli endotoxin in broiler chickens","volume":"74","author":"Takahashi","year":"1995","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.psj.2021.101199_bib0033","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/nri2653","article-title":"Intestinal mucosal barrier function in health and disease","volume":"9","author":"Turner","year":"2009","journal-title":"Nat. Rev. Immunol."},{"issue":"Suppl.","key":"10.1016\/j.psj.2021.101199_bib0034","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1097\/00003246-200201001-00009","article-title":"Endotoxin tolerance: a review","volume":"30","author":"West","year":"2002","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.psj.2021.101199_bib0035","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.vetimm.2013.02.006","article-title":"The effects of natural and modified clinoptilolite on intestinal barrier function and immune response to LPS in broiler chickens","volume":"153","author":"Wu","year":"2013","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2021.101199_bib0036","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3382\/ps.2012-02645","article-title":"Effects of feeding fermented Ginkgo biloba leaves on small intestinal morphology, absorption, and immunomodulation of early lipopolysaccharide-challenged chicks","volume":"92","author":"Zhang","year":"2013","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101199_bib0037","doi-asserted-by":"crossref","first-page":"5389","DOI":"10.1016\/j.psj.2020.08.007","article-title":"Effects of dietary pyrroloquinoline quinone disodium supplementation on inflammatory responses, oxidative stress, and intestinal morphology in broiler chickens challenged with lipopolysaccharide","volume":"99","author":"Zheng","year":"2020","journal-title":"Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579121002339?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579121002339?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:37:55Z","timestamp":1758494275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579121002339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S0032579121002339"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2021.101199","relation":{},"ISSN":["0032-5791"],"issn-type":[{"type":"print","value":"0032-5791"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of serum antioxidative status, immune status and intestinal condition of Linwu duck challenged by lipopolysaccharide with various dosages and replications","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2021.101199","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"101199"}}