{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:08:46Z","timestamp":1791256126176,"version":"4.1.0"},"reference-count":84,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Republic of China Ministry of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.psj.2021.101412","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T23:16:15Z","timestamp":1627686975000},"page":"101412","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"title":["Effects of novel microecologics combined with traditional Chinese medicine and probiotics on growth performance and health of broilers"],"prefix":"10.1016","volume":"101","author":[{"given":"Jin","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2021.101412_bib0001","doi-asserted-by":"crossref","first-page":"54","DOI":"10.2174\/1389200219666180523102920","article-title":"Application of traditional Chinese herbal medicine by-products as dietary feed supplements and antibiotic replacements in animal production","volume":"20","author":"Abdallah","year":"2019","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.psj.2021.101412_bib0002","doi-asserted-by":"crossref","first-page":"10611","DOI":"10.1007\/s11356-018-1687-x","article-title":"The use of probiotics as eco-friendly alternatives for antibiotics in poultry nutrition","volume":"25","author":"Alagawany","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.psj.2021.101412_bib0003","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.anifeedsci.2014.10.012","article-title":"Effects of dietary Bacillus subtilis on heat-stressed broilers performance, intestinal morphology and microflora composition","volume":"198","author":"Al-Fataftah","year":"2014","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0004","doi-asserted-by":"crossref","first-page":"251","DOI":"10.5625\/lar.2017.33.3.251","article-title":"Safety of 8-weeks oral administration of Arctium lappa L","volume":"33","author":"Bok","year":"2017","journal-title":"Lab. Anim. Res."},{"key":"10.1016\/j.psj.2021.101412_bib0005","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.csbj.2018.03.002","article-title":"Current perspectives of the chicken gastrointestinal tract and its microbiome","volume":"16","author":"Borda-Molina","year":"2018","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.psj.2021.101412_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110420","article-title":"Compound probiotics alleviating aflatoxin B1 and zearalenone toxic effects on broiler production performance and gut microbiota","volume":"194","author":"Chang","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.psj.2021.101412_bib0007","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jep.2015.12.031","article-title":"Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs","volume":"179","author":"Chen","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0008","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3389\/fphar.2019.00535","article-title":"Glycyrrhetinic acid maintains intestinal homeostasis via HuR","volume":"10","author":"Chen","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0009","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.anifeedsci.2017.12.002","article-title":"Different essential oils in diets of chickens: 1. Growth performance, nutrient utilisation, nitrogen excretion, carcass traits and chemical composition of meat","volume":"236","author":"Chowdhury","year":"2018","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0010","doi-asserted-by":"crossref","first-page":"986","DOI":"10.3390\/ani9110986","article-title":"The facilitating effect of tartary buckwheat flavonoids and Lactobacillus plantarum on the growth performance, nutrient digestibility, antioxidant capacity, and fecal microbiota of weaned piglets","volume":"9","author":"Cui","year":"2019","journal-title":"Animals (Basel)."},{"key":"10.1016\/j.psj.2021.101412_bib0011","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3382\/ps\/pez525","article-title":"Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers","volume":"99","author":"De Grande","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0012","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/0091270002042001003","article-title":"Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications","volume":"42","author":"Fung","year":"2002","journal-title":"J. Clin. Pharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0013","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201800636","article-title":"Dietary black raspberries impact the colonic microbiome and phytochemical metabolites in mice","volume":"63","author":"Gu","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.psj.2021.101412_bib0014","doi-asserted-by":"crossref","first-page":"985","DOI":"10.3390\/ani9110985","article-title":"Effects of probiotics as antibiotics substitutes on growth performance, serum biochemical parameters, intestinal morphology, and barrier function of broilers","volume":"9","author":"He","year":"2019","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.psj.2021.101412_bib0015","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/nrgastro.2014.66","article-title":"Expert consensus document: the International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic","volume":"11","author":"Hill","year":"2014","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.psj.2021.101412_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.anifeedsci.2019.114272","article-title":"The effects of heat-killed Lactobacillus plantarum L-137 supplementation on growth performance, intestinal morphology, and immune-related gene expression in broiler chickens","volume":"257","author":"Incharoen","year":"2019","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0017","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3390\/antiox9030250","article-title":"Dietary postbiotic Lactobacillus plantarum improves serum and ruminal antioxidant activity and upregulates hepatic antioxidant enzymes and ruminal barrier function in post-weaning lambs","volume":"9","author":"Izuddin","year":"2020","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.psj.2021.101412_bib0018","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3390\/antiox8120575","article-title":"Dietary stevioside supplementation alleviates lipopolysaccharide-induced intestinal mucosal damage through anti-inflammatory and antioxidant effects in broiler chickens","volume":"8","author":"Jiang","year":"2019","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.psj.2021.101412_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112439","article-title":"An \u201cessential herbal medicine\u201d\u2014licorice: a review of phytochemicals and its effects in combination preparations","volume":"249","author":"Jiang","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0020","doi-asserted-by":"crossref","first-page":"4783","DOI":"10.3892\/mmr.2020.11539","article-title":"Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress","volume":"22","author":"Jiang","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.psj.2021.101412_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.113954","article-title":"Andrographis paniculata (Burm.f.) Nees and its major constituent andrographolide as potential antiviral agents","volume":"272","author":"Jiang","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0022","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.anifeedsci.2018.10.008","article-title":"The effect of microbiome modulation on the intestinal health of poultry","volume":"250","author":"Kogut","year":"2018","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0023","doi-asserted-by":"crossref","first-page":"88175","DOI":"10.1016\/j.nut.2018.10.002","article-title":"Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet","volume":"60","author":"Kong","year":"2019","journal-title":"Nutrition"},{"key":"10.1016\/j.psj.2021.101412_bib0024","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.3389\/fimmu.2019.03057","article-title":"Blocking of the CXCR4-CXCL12 interaction inhibits the migration of chicken B cells into the bursa of Fabricius","volume":"10","author":"Laparidou","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.psj.2021.101412_bib0025","doi-asserted-by":"crossref","first-page":"3860","DOI":"10.1021\/acs.molpharmaceut.8b00347","article-title":"Diammonium glycyrrhizinate protects against nonalcoholic fatty liver disease in mice through modulation of gut microbiota and restoration of intestinal barrier","volume":"15","author":"Li","year":"2018","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.psj.2021.101412_bib0026","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.carbpol.2019.03.051","article-title":"Structural characterization and rheological properties of a pectin with anti-constipation activity from the roots of Arctium lappa L","volume":"215","author":"Li","year":"2019","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.psj.2021.101412_bib0027","doi-asserted-by":"crossref","first-page":"4428","DOI":"10.1039\/D0FO00128G","article-title":"Mechanisms for Lactobacillus rhamnosus treatment of intestinal infection by drug-resistant Escherichia coli","volume":"11","author":"Li","year":"2020","journal-title":"Food Funct"},{"key":"10.1016\/j.psj.2021.101412_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.01.030","article-title":"Effects of Taraxacum and Astragalus extracts combined with probiotic Bacillus subtilis and Lactobacillus on Escherichia coli-infected broiler chickens","volume":"100","author":"Liang","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0029","article-title":"Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemmapentaphyllum","volume":"24","author":"Liao","year":"2020","journal-title":"Gut Microbes"},{"key":"10.1016\/j.psj.2021.101412_bib0030","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.14202\/vetworld.2020.2209-2215","article-title":"The effect of Aspergillus niger as a dietary supplement on blood parameters, intestinal morphology, and gut microflora in Haidong chicks reared in a high altitude environment","volume":"13","author":"Lin","year":"2020","journal-title":"Vet. World."},{"key":"10.1016\/j.psj.2021.101412_bib0031","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.3382\/ps\/pex017","article-title":"The effects of Bacillus coagulans-fermented and non-fermented Ginkgo biloba on abdominal fat deposition and meat quality of Peking duck","volume":"96","author":"Liu","year":"2017","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0032","doi-asserted-by":"crossref","first-page":"568","DOI":"10.5713\/ajas.19.0179","article-title":"Effects of supplemented culture media from solid-state fermented Isaria cicadae on performance, serum biochemical parameters, serum immune indexes, antioxidant capacity and meat quality of broiler chickens","volume":"33","author":"Liu","year":"2020","journal-title":"Asian-Austr. J. Anim. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0033","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2021.101412_bib0034","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.psj.2019.10.043","article-title":"Effects of dietary Lycium barbarum polysaccharides on growth performance, digestive enzyme activities, antioxidant status, and immunity of broiler chickens","volume":"99","author":"Long","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0035","doi-asserted-by":"crossref","first-page":"4769","DOI":"10.1016\/j.ejmech.2011.07.057","article-title":"Natural products: an evolving role in future drug discovery","volume":"46","author":"Mishra","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.psj.2021.101412_bib0036","doi-asserted-by":"crossref","first-page":"4408","DOI":"10.3382\/ps\/pez246","article-title":"Effect of a synbiotic supplement on cecal microbial ecology, antioxidant status, and immune response of broiler chickens reared under heat stress","volume":"98","author":"Mohammed","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0037","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3390\/antiox8120571","article-title":"Andrographolide, a natural antioxidant: an update","volume":"8","author":"Mussard","year":"2019","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.psj.2021.101412_bib0038","series-title":"Nutrient Requirements of Poultry","year":"1994"},{"key":"10.1016\/j.psj.2021.101412_bib0039","doi-asserted-by":"crossref","first-page":"869","DOI":"10.3382\/ps\/pew313","article-title":"Effect of supplemental fermented Ginkgo biloba leaves at different levels on growth performance, meat quality, and antioxidant status of breast and thigh muscles in broiler chickens","volume":"96","author":"Niu","year":"2017","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0040","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.anifeedsci.2019.01.003","article-title":"Effect of different doses of fermented Ginkgo biloba leaves on serum biochemistry, antioxidant capacity hepatic gene expression in broilers","volume":"248","author":"Niu","year":"2019","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0041","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.freeradbiomed.2019.04.005","article-title":"Gut microbiota modulation and anti-inflammatory properties of anthocyanins from the fruits of Lycium ruthenicum Murray in dextran sodium sulfate-induced colitis in mice","volume":"136","author":"Peng","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.psj.2021.101412_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2019.108952","article-title":"Effects of long-term intake of anthocyanins from Lycium ruthenicum Murray on the organism health and gut microbiota in vivo","volume":"130","author":"Peng","year":"2020","journal-title":"Food Res. Int."},{"key":"10.1016\/j.psj.2021.101412_bib0043","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00176-20","article-title":"Increasing the hindgut carbohydrate\/protein ratio by cecal infusion of corn starch or casein hydrolysate drives gut microbiota-related bile acid metabolism to stimulate colonic barrier function","volume":"5","author":"Pi","year":"2020","journal-title":"mSystems."},{"key":"10.1016\/j.psj.2021.101412_bib0044","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1017\/S1751731118001520","article-title":"Dietary essential oils improve feed efficiency and hepatic antioxidant content of broiler chickens","volume":"13","author":"Pirgozliev","year":"2019","journal-title":"Animal"},{"key":"10.1016\/j.psj.2021.101412_bib0045","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.blre.2008.10.001","article-title":"Splenomegaly: investigation, diagnosis and management","volume":"23","author":"Pozo","year":"2009","journal-title":"Blood Rev"},{"key":"10.1016\/j.psj.2021.101412_bib0046","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1053\/j.gastro.2020.06.038","article-title":"IL1B increases intestinal tight junction permeability by upregulation of MIR200C-3p, which degrades occludin mRNA","volume":"159","author":"Rawat","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psj.2021.101412_bib0047","doi-asserted-by":"crossref","first-page":"4131","DOI":"10.1091\/mbc.11.12.4131","article-title":"Complex phenotype of mice lacking occludin, a component of tight junction strands","volume":"11","author":"Saitou","year":"2000","journal-title":"Mol. Biol. Cell."},{"key":"10.1016\/j.psj.2021.101412_bib0048","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s13568-018-0682-4","article-title":"Fermented astragalus in diet altered the composition of fecal microbiota in broiler chickens","volume":"8","author":"Qiao","year":"2018","journal-title":"AMB Express"},{"key":"10.1016\/j.psj.2021.101412_bib0049","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.3382\/ps\/pex091","article-title":"Effects of dietary gallic acid supplementation on performance, antioxidant status, and jejunum intestinal morphology in broiler chicks","volume":"96","author":"Samuel","year":"2017","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0050","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1042\/BA20080023","article-title":"Production of the monoterpene limonene and modulation of apoptosis-related proteins in embryonic-mouse NIH 3T3 fibroblast cells by introduction of the limonene synthase gene isolated from Japanese catnip (Schizonepeta tenuifolia)","volume":"52","author":"Satomi","year":"2009","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.psj.2021.101412_bib0051","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.1007\/s11356-016-8206-8","article-title":"Effects of dietary inclusion level of a mixture of probiotic cultures and enzymes on broiler chickens immunity response","volume":"24","author":"Seidavi","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.psj.2021.101412_bib0053","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.3390\/ani10101744","article-title":"Effects of dietary andrographolide levels on growth performance, antioxidant capacity, intestinal immune function and microbioma of rice field eel (Monopterus Albus)","volume":"10","author":"Shi","year":"2020","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.psj.2021.101412_bib0052","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1538\/expanim.57.11","article-title":"Licorice extract does not impair the male reproductive function of rats","volume":"57","author":"Shin","year":"2008","journal-title":"Exp. Anim."},{"key":"10.1016\/j.psj.2021.101412_bib0054","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.anifeedsci.2018.04.027","article-title":"Broiler production without antibiotics: United States field perspectives","volume":"250","author":"Smith","year":"2019","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0055","doi-asserted-by":"crossref","first-page":"5205","DOI":"10.1039\/D0FO00007H","article-title":"The ameliorative effect of Lactobacillus plantarum-12 on DSS-induced murine colitis","volume":"11","author":"Sun","year":"2020","journal-title":"Food Funct"},{"key":"10.1016\/j.psj.2021.101412_bib0056","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/1040841X.2017.1373062","article-title":"Alternatives to antibiotics in poultry feed: molecular perspectives","volume":"44","author":"Suresh","year":"2018","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.psj.2021.101412_bib0057","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00570-19","article-title":"Immunomodulatory effects of Lactobacillus plantarum on inflammatory response induced by Klebsiella pneumoniae","volume":"87","author":"Vareille-Delarbre","year":"2019","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psj.2021.101412_bib0058","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.anifeedsci.2017.03.015","article-title":"Production performance, immunity, and heat stress resistance in Jersey cattle fed a concentrate fermented with probiotics in the presence of a Chinese herbal combination","volume":"228","author":"Wang","year":"2017","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2021.101412_bib0059","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00253-019-10259-6","article-title":"Combination of probiotics with different functions alleviate DSS-induced colitis by regulating intestinal microbiota, IL-10, and barrier function","volume":"104","author":"Wang","year":"2020","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2021.101412_bib0060","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3389\/fvets.2020.00042","article-title":"Lactobacillus reuteri promotes intestinal development and regulates mucosal immune function in newborn piglets","volume":"7","author":"Wang","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0061","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.toxrep.2019.05.003","article-title":"Acute oral toxicity evaluation of Andrographis paniculata-standardized first true leaf ethanolic extract","volume":"6","author":"Worasuttayangkurn","year":"2019","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.psj.2021.101412_bib0062","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.3382\/ps\/pev013","article-title":"Effects of feed supplemented with fermented pine needles (Pinus ponderosa) on growth performance and antioxidant status in broilers","volume":"94","author":"Wu","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0063","doi-asserted-by":"crossref","first-page":"7081","DOI":"10.1039\/C9FO00904C","article-title":"Effect of supplementation of nicotinamide and sodium butyrate on the growth performance, liver mitochondrial function and gut microbiota of broilers at high stocking density","volume":"10","author":"Wu","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.psj.2021.101412_bib0064","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jep.2014.12.021","article-title":"Acute and subchronic toxicity as well as evaluation of safety pharmacology of Galla chinensis solution","volume":"162","author":"Xiang","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2021.101412_bib0065","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.phymed.2014.11.006","article-title":"Arctigenic acid, the key substance responsible for the hypoglycemic activity of Fructus Arctii","volume":"22","author":"Xu","year":"2015","journal-title":"Phytomedicine"},{"key":"10.1016\/j.psj.2021.101412_bib0066","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s12917-020-2264-3","article-title":"Effects of Lactobacillus plantarum on intestinal integrity and immune responses of egg-laying chickens infected with Clostridium perfringens under the free-range or the specific pathogen free environment","volume":"16","author":"Xu","year":"2020","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2021.101412_bib0067","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1039\/C7FO01677H","article-title":"The effect of fucoidan on intestinal flora and intestinal barrier function in rats bearing breast cancer","volume":"9","author":"Xue","year":"2018","journal-title":"Food Funct"},{"key":"10.1016\/j.psj.2021.101412_bib0068","doi-asserted-by":"crossref","first-page":"3830","DOI":"10.1080\/10408398.2016.1152230","article-title":"Regulation of the intestinal tight junction by natural polyphenols: a mechanistic perspective","volume":"57","author":"Yang","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.psj.2021.101412_bib0069","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1093\/jas\/skz078","article-title":"Dietary leonurine hydrochloride supplementation attenuates lipopolysaccharide challenge-induced intestinal inflammation and barrier dysfunction by inhibiting the NF-\u03baB\/MAPK signaling pathway in broilers","volume":"97","author":"Yang","year":"2019","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0070","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.phymed.2018.09.189","article-title":"Ethanol extract of Glycyrrhizae Radix modulates the responses of antigen-specific splenocytes in experimental autoimmune encephalomyelitis","volume":"54","author":"Yang","year":"2019","journal-title":"Phytomedicine"},{"key":"10.1016\/j.psj.2021.101412_bib0071","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111139","article-title":"Selenium-enriched yeast reduces caecal pathological injuries and intervenes changes of the diversity of caecal microbiota caused by Ochratoxin-A in broilers","volume":"137","author":"Yang","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.psj.2021.101412_bib0072","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.3389\/fmicb.2019.02662","article-title":"Dietary supplementation with citrus extract altered the intestinal microbiota and microbial metabolite profiles and enhanced the mucosal immune homeostasis in yellow-feathered broilers","volume":"10","author":"Yu","year":"2019","journal-title":"Front Microbiol"},{"key":"10.1016\/j.psj.2021.101412_bib0073","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/ptr.3659","article-title":"Screening for anti-inflammatory and bronchorelaxant activities of 12 commonly used Chinese herbal medicines","volume":"26","author":"Yue","year":"2012","journal-title":"Phytother Res"},{"key":"10.1016\/j.psj.2021.101412_bib0074","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/08941939.2012.664099","article-title":"History of antibiotics. From salvarsan to cephalosporins","volume":"25","author":"Zaffiri","year":"2012","journal-title":"J. Invest. Surg."},{"key":"10.1016\/j.psj.2021.101412_bib0075","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1007\/s11250-019-01930-1","article-title":"Dietary supplementation of Aspergillus oryzae meal and its effect on performance, carcass characteristics, blood variables, and immunity of broiler chickens","volume":"51","author":"Zahirian","year":"2019","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.psj.2021.101412_bib0076","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1080\/00071668.2015.1030590","article-title":"Effects of dietary supplementation with fermented ginkgo leaves on antioxidant capacity, intestinal morphology and microbial ecology in broiler chicks","volume":"56","author":"Zhang","year":"2015","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0077","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.lfs.2019.03.037","article-title":"Arctigenin ameliorates renal impairment and inhibits endoplasmic reticulum stress in diabetic db\/db mice","volume":"223","author":"Zhang","year":"2019","journal-title":"Life Sci"},{"key":"10.1016\/j.psj.2021.101412_bib0078","doi-asserted-by":"crossref","first-page":"10838","DOI":"10.3168\/jds.2019-16593","article-title":"Short communication: complete genome sequence of Lactobacillus plantarum J26, a probiotic strain with immunomodulatory activity","volume":"102","author":"Zhang","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0079","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fphar.2019.00013","article-title":"Protective effects of 18\u03b2-glycyrrhetinic acid on monocrotaline-induced pulmonary arterial hypertension in rats","volume":"10","author":"Zhang","year":"2019","journal-title":"Front. Pharmacol"},{"key":"10.1016\/j.psj.2021.101412_bib0080","article-title":"Dietary supplementation with Bacillus subtilis promotes growth performance of broilers by altering the dominant microbial community","volume":"100","author":"Zhang","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0081","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.3382\/ps\/pez059","article-title":"Effects of dietary phytosterols on growth performance, antioxidant status, and meat quality in Partridge Shank chickens","volume":"98","author":"Zhao","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2021.101412_bib0082","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/asj.12361","article-title":"Effects of dietary supplementation of fermented Ginkgo biloba L. residues on growth performance, nutrient digestibility, serum biochemical parameters and immune function in weaned piglets","volume":"86","author":"Zhou","year":"2015","journal-title":"Anim. Sci. J."},{"key":"10.1016\/j.psj.2021.101412_bib0083","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2915.2009.00809.x","article-title":"Efficacy and safety of catnip (Nepeta cataria) as a novel filth fly repellent","volume":"23","author":"Zhu","year":"2009","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.psj.2021.101412_bib0084","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.3382\/ps\/pez279","article-title":"Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers","volume":"98","author":"Zou","year":"2019","journal-title":"Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579121004351?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579121004351?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:38:47Z","timestamp":1758494327000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579121004351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":84,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0032579121004351"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2021.101412","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of novel microecologics combined with traditional Chinese medicine and probiotics on growth performance and health of broilers","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2021.101412","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"101412"}}