{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:47:20Z","timestamp":1793134040878,"version":"4.5.0"},"reference-count":81,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T00:00:00Z","timestamp":1646870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.psj.2022.101858","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T03:14:09Z","timestamp":1647314049000},"page":"101858","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Influence of dietary vitamin E and selenium supplementation on broilers subjected to heat stress, Part II: oxidative stress, immune response, gut integrity, and intestinal microbiota"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-9321","authenticated-orcid":false,"given":"Ali","family":"Calik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3657-7728","authenticated-orcid":false,"given":"Nima K.","family":"Emami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghislain","family":"Schyns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallory B.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis F.","family":"Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami A.","family":"Dalloul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2022.101858_bib0001","series-title":"Pages 171-217 in Basic Principles and Clinical Significance of Oxidative Stress","article-title":"Rooibos (Aspalathus linearis) and its major flavonoids\u2014potential against oxidative stress-induced conditions","author":"Ajuwon","year":"2015"},{"key":"10.1016\/j.psj.2022.101858_bib0002","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3354\/ame01753","article-title":"Minor revision to V4 region SSU rRNA 806R gene primer greatly increases detection of SAR11 bacterioplankton","volume":"75","author":"Apprill","year":"2015","journal-title":"Aquat. Microb. Ecol."},{"key":"10.1016\/j.psj.2022.101858_bib0003","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s12192-009-0109-x","article-title":"Heat stress upregulates chaperone heat shock protein 70 and antioxidant manganese superoxide dismutase through reactive oxygen species (ROS), p38MAPK, and Akt","volume":"14","author":"Banerjee Mustafi","year":"2009","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.psj.2022.101858_bib0004","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1089\/ars.2012.4994","article-title":"Oxidative stress and the DNA mismatch repair pathway","volume":"18","author":"Brierley","year":"2013","journal-title":"Antioxid. Redox Signal"},{"key":"10.1016\/j.psj.2022.101858_bib0005","series-title":"The Resource Outlook to 2050: By How Much Do Land, Water and Crop Yields Need to Increase by 2050","author":"Bruinsma","year":"2009"},{"key":"10.1016\/j.psj.2022.101858_bib0006","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.3382\/ps\/pev182","article-title":"Effect of lactulose supplementation on growth performance, intestinal histomorphology, cecal microbial population, and short-chain fatty acid composition of broiler chickens","volume":"94","author":"Calik","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0007","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/j.psj.2019.10.061","article-title":"Bacillus licheniformis-fermented products improve growth performance and the fecal microbiota community in broilers","volume":"99","author":"Chen","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0008","article-title":"Potential role of amino acids in the adaptation of chicks and market-age broilers to heat stress","volume":"7","author":"Chowdhury","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0009","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1186\/s12917-018-1578-x","article-title":"Effects of vitamin E, inorganic selenium, bacterial organic selenium, and their combinations on immunity response in broiler chickens","volume":"14","author":"Dalia","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2022.101858_bib0010","series-title":"Pages 43-82 in Oxidative Stress in Microbial Diseases","article-title":"Role of gut microbiota in combating oxidative stress","author":"Dam","year":"2019"},{"key":"10.1016\/j.psj.2022.101858_bib0011","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2353\/ajpath.2008.070522","article-title":"Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: regulatory role of heat shock factor-1","volume":"172","author":"Dokladny","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.psj.2022.101858_bib0012","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.3389\/fimmu.2019.01620","article-title":"A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-alpha induced inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients by targeting MAPK and AKT\/mTOR signal pathway","volume":"10","author":"Du","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2022.101858_bib0013","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1055\/s-0029-1220724","article-title":"Selenium and inflammation: underlying anti-inflammatory mechanisms","volume":"41","author":"Duntas","year":"2009","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.psj.2022.101858_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.707757","article-title":"Heat stress and feed restriction distinctly affect performance, carcass and meat yield, intestinal integrity, and inflammatory (chemo)cytokines in broiler chickens","volume":"12","author":"Emami","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.psj.2022.101858_bib0015","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3390\/antiox10010035","article-title":"Radical response: effects of heat stress-induced oxidative stress on lipid metabolism in the avian liver","volume":"10","author":"Emami","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2022.101858_bib0016","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1080\/15384101.2015.1041684","article-title":"Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation","volume":"14","author":"Fazolini","year":"2015","journal-title":"Cell Cycle"},{"key":"10.1016\/j.psj.2022.101858_bib0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-9255-11-19","article-title":"Heat shock protein 70 down-regulates the production of toll-like receptor-induced pro-inflammatory cytokines by a heat shock factor-1\/constitutive heat shock element-binding factor-dependent mechanism","volume":"11","author":"Ferat-Osorio","year":"2014","journal-title":"J. Inflamm."},{"key":"10.1016\/j.psj.2022.101858_bib0018","doi-asserted-by":"crossref","first-page":"750","DOI":"10.3390\/ani11030750","article-title":"Phytogenic water additives improve broiler growth performance via modulation of intermediary metabolism-related signaling pathways","volume":"11","author":"Flees","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.psj.2022.101858_bib0019","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1007\/s00253-017-8688-4","article-title":"Selenium nanoparticles in poultry feed modify gut microbiota and increase abundance of Faecalibacterium prausnitzii","volume":"102","author":"Gangadoo","year":"2018","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2022.101858_bib0020","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0014-5793(99)00094-0","article-title":"Antioxidant-mediated inhibition of the heat shock response leads to apoptosis","volume":"445","author":"Gorman","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.psj.2022.101858_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2020.10.055","article-title":"Research Note: Phytobiotics modulate the expression profile of circulating inflammasome and cyto(chemo)kine in whole blood of broilers exposed to cyclic heat stress","volume":"100","author":"Greene","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0022","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3382\/ps.2011-01628","article-title":"Overexpression of heat shock protein 70 and its relationship to intestine under acute heat stress in broilers: 2. Intestinal oxidative stress","volume":"91","author":"Gu","year":"2012","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0023","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s00484-013-0654-y","article-title":"Effects of dietary selenium and vitamin E on immune response and biological blood parameters of broilers reared under thermoneutral or heat stress conditions","volume":"58","author":"Habibian","year":"2014","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.psj.2022.101858_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.734942","article-title":"Effects of antioxidant supplementation (nano\u2011selenium, vitamin C and E) on growth performance, blood biochemistry, immune status and body composition of rainbow trout (Oncorhynchus mykiss) under sub-lethal ammonia exposure","volume":"521","author":"Harsij","year":"2020","journal-title":"Aquaculture"},{"key":"10.1016\/j.psj.2022.101858_bib0025","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s12011-012-9374-0","article-title":"Effects of dietary selenium, vitamin E, and their combination on growth, serum metabolites, and antioxidant defense system in skeletal muscle of broilers under heat stress","volume":"148","author":"Harsini","year":"2012","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2022.101858_bib0026","doi-asserted-by":"crossref","first-page":"6378","DOI":"10.3382\/ps\/pez471","article-title":"Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers","volume":"98","author":"He","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-0378(02)00060-8","article-title":"Cytokines and the immune-testicular axis","volume":"58","author":"Hedger","year":"2003","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.psj.2022.101858_bib0028","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ajme.2017.09.001","article-title":"First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid","volume":"54","author":"Ighodaro","year":"2018","journal-title":"Alexandria J. Med."},{"key":"10.1016\/j.psj.2022.101858_bib0029","doi-asserted-by":"crossref","first-page":"749","DOI":"10.5713\/ajas.2013.13852","article-title":"Effects of Vitamin C or E on the pro-inflammatory cytokines, heat shock protein 70 and antioxidant status in broiler chicks under summer conditions","volume":"27","author":"Jang","year":"2014","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0030","first-page":"355","article-title":"Selenium-enriched probiotics improve hepatic protection by regulating pro-inflammatory cytokines and antioxidant capacity in broilers under heat stress conditions","volume":"6","author":"Khan","year":"2019","journal-title":"J. Adv. Vet."},{"key":"10.1016\/j.psj.2022.101858_bib0031","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s13568-018-0641-0","article-title":"Impacts of selenium and vitamin E supplementation on mRNA of heat shock proteins, selenoproteins and antioxidants in broilers exposed to high temperature","volume":"8","author":"Kumbhar","year":"2018","journal-title":"AMB Express"},{"key":"10.1016\/j.psj.2022.101858_bib0032","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3390\/ani3020356","article-title":"Impact of heat stress on poultry production","volume":"3","author":"Lara","year":"2013","journal-title":"Animals"},{"key":"10.1016\/j.psj.2022.101858_bib0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2012.00140","article-title":"Opposing roles for heat and heat shock proteins in macrophage functions during inflammation: a function of cell activation state?","volume":"3","author":"Lee","year":"2012","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2022.101858_bib0034","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3390\/nu12030734","article-title":"Beyond heat stress: intestinal integrity disruption and mechanism-based intervention strategies","volume":"12","author":"Lian","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.psj.2022.101858_bib0035","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cbpa.2006.01.032","article-title":"Acute heat stress induces oxidative stress in broiler chickens","volume":"144","author":"Lin","year":"2006","journal-title":"Comp. Biochem. Physiol. A. Mol. Integr. Physiol."},{"key":"10.1016\/j.psj.2022.101858_bib0036","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1039\/C5FO01338K","article-title":"Resveratrol modulates intestinal morphology and HSP70\/90, NF-kappaB and EGF expression in the jejunal mucosa of black-boned chickens on exposure to circular heat stress","volume":"7","author":"Liu","year":"2016","journal-title":"Food Funct."},{"key":"10.1016\/j.psj.2022.101858_bib0037","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2022.101858_bib0038","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/jam.13347","article-title":"Phylogenetic and functional characterization of the distal intestinal microbiome of rainbow trout Oncorhynchus mykiss from both farm and aquarium settings","volume":"122","author":"Lyons","year":"2017","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.psj.2022.101858_bib0039","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.3390\/ani11082288","article-title":"The dynamic conversion of dietary protein and amino acids into chicken-meat protein","volume":"11","author":"Macelline","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.psj.2022.101858_bib0040","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.humic.2018.07.002","article-title":"Linking gut redox to human microbiome","volume":"10","author":"Million","year":"2018","journal-title":"Hum. Microbiome J."},{"key":"10.1016\/j.psj.2022.101858_bib0041","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1152\/japplphysiol.00412.2005","article-title":"Thiol supplementation in aged animals alters antioxidant enzyme activity after heat stress","volume":"99","author":"Morrison","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.psj.2022.101858_bib0042","series-title":"Nutrient Requirements of Poultry","year":"1994"},{"key":"10.1016\/j.psj.2022.101858_bib0043","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/1462-2920.13023","article-title":"Every base matters: assessing small subunit rRNA primers for marine microbiomes with mock communities, time series and global field samples","volume":"18","author":"Parada","year":"2016","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.psj.2022.101858_bib0044","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1093\/bioinformatics\/btu494","article-title":"STAMP: statistical analysis of taxonomic and functional profiles","volume":"30","author":"Parks","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.psj.2022.101858_bib0045","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.3382\/ps\/pez149","article-title":"Effect of vitamin E sources and inclusion levels in diets on growth performance, meat quality, alpha-tocopherol retention, and intestinal inflammatory cytokine expression in broiler chickens","volume":"98","author":"Pitargue","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0046","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.3382\/ps.2010-00812","article-title":"Heat stress impairs performance parameters, induces intestinal injury, and decreases macrophage activity in broiler chickens","volume":"89","author":"Quinteiro-Filho","year":"2010","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0047","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.vetimm.2017.02.006","article-title":"Heat stress decreases expression of the cytokines, avian \u03b2-defensins 4 and 6 and Toll-like receptor 2 in broiler chickens infected with Salmonella Enteritidis","volume":"186","author":"Quinteiro-Filho","year":"2017","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2022.101858_bib0048","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3389\/fgene.2017.00192","article-title":"Noni (Morinda citrifolia) modulates the hypothalamic expression of stress- and metabolic-related genes in broilers exposed to acute heat stress","volume":"8","author":"Rajaei-Sharifabadi","year":"2017","journal-title":"Front. Genet."},{"key":"10.1016\/j.psj.2022.101858_bib0049","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.mgene.2015.08.003","article-title":"Expression profile of six stress-related genes and productive performances of fast and slow growing broiler strains reared under heat stress conditions","volume":"6","author":"Rimoldi","year":"2015","journal-title":"Meta Gene"},{"key":"10.1016\/j.psj.2022.101858_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1600-079X.2003.00092.x","article-title":"Regulation of antioxidant enzymes: a significant role for melatonin","volume":"36","author":"Rodriguez","year":"2004","journal-title":"J. Pineal. Res."},{"key":"10.1016\/j.psj.2022.101858_bib0051","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1439-0396.2010.01123.x","article-title":"Resveratrol protects quail hepatocytes against heat stress: modulation of the Nrf2 transcription factor and heat shock proteins","volume":"96","author":"Sahin","year":"2012","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.psj.2022.101858_bib0052","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.3382\/ps.2008-00560","article-title":"Role of dietary zinc in heat-stressed poultry: a review","volume":"88","author":"Sahin","year":"2009","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0053","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1080\/03079457.2019.1648750","article-title":"Effects of a feed additive blend on broilers challenged with heat stress","volume":"48","author":"Santos","year":"2019","journal-title":"Avian Pathol"},{"key":"10.1016\/j.psj.2022.101858_bib0054","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.ceb.2005.09.009","article-title":"Growing roles for the mTOR pathway","volume":"17","author":"Sarbassov","year":"2005","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.psj.2022.101858_bib0055","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol."},{"key":"10.1016\/j.psj.2022.101858_bib0056","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1096\/fasebj.10.7.8635688","article-title":"Antioxidant and redox regulation of gene transcription","volume":"10","author":"Sen","year":"1996","journal-title":"FASEB J."},{"key":"10.1016\/j.psj.2022.101858_bib0057","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.3382\/ps\/pez026","article-title":"Impact of gut microbiota structure in heat-stressed broilers","volume":"98","author":"Shi","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0058","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-75885-x","article-title":"Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine","volume":"10","author":"Siddiqui","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2022.101858_bib0059","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1080\/00071660601040079","article-title":"Effects of dietary supplements of selenium, vitamin E or combinations of the two on antibody responses of broilers","volume":"47","author":"Singh","year":"2006","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0060","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/jpn.12379","article-title":"Heat stress effects on livestock: molecular, cellular and metabolic aspects, a review","volume":"100","author":"Slimen","year":"2016","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.psj.2022.101858_bib0061","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jcrc.2007.09.007","article-title":"Heat shock factor 1 inhibits nuclear factor\u2013\u03baB nuclear binding activity during endotoxin tolerance and heat shock","volume":"23","author":"Song","year":"2008","journal-title":"J. Crit. Care"},{"key":"10.1016\/j.psj.2022.101858_bib0062","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s12192-015-0621-0","article-title":"Transcriptome response to heat stress in a chicken hepatocellular carcinoma cell line","volume":"20","author":"Sun","year":"2015","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.psj.2022.101858_bib0063","series-title":"Selenium in Poultry Nutrition and Health","author":"Surai","year":"2018"},{"key":"10.1016\/j.psj.2022.101858_bib0064","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.3382\/ps\/pez072","article-title":"Nutritional modulation of the antioxidant capacities in poultry: the case of vitamin E","volume":"98","author":"Surai","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0065","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3390\/antiox8070235","article-title":"Antioxidant defence systems and oxidative stress in poultry biology: an update","volume":"8","author":"Surai","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2022.101858_bib0066","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3382\/ps.2009-00318","article-title":"Effects of different acute high ambient temperatures on function of hepatic mitochondrial respiration, antioxidative enzymes, and oxidative injury in broiler chickens","volume":"89","author":"Tan","year":"2010","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0067","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1016\/j.psj.2019.12.046","article-title":"High-temperature exposure alters the community structure and functional features of the intestinal microbiota in Shaoxing ducks (Anas platyrhynchos)","volume":"99","author":"Tian","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0068","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s11274-021-03004-7","article-title":"SigB-regulated antioxidant functions in gram-positive bacteria","volume":"37","author":"Tran","year":"2021","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2022.101858_bib0069","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00484-020-02023-7","article-title":"Heat stress and poultry production: impact and amelioration","volume":"65","author":"Vandana","year":"2021","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.psj.2022.101858_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138975","article-title":"Differences in susceptibility to heat stress along the chicken intestine and the protective effects of galacto-oligosaccharides","volume":"10","author":"Varasteh","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2022.101858_bib0071","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.3382\/ps\/pey032","article-title":"Effects of high ambient temperature on the community structure and composition of ileal microbiome of broilers","volume":"97","author":"Wang","year":"2018","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0072","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.4049\/jimmunol.1700152","article-title":"IL-22 increases permeability of intestinal epithelial tight junctions by enhancing Claudin-2 expression","volume":"199","author":"Wang","year":"2017","journal-title":"J. Immunol."},{"key":"10.1016\/j.psj.2022.101858_bib0073","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1093\/bioinformatics\/btx617","article-title":"Nephele: a cloud platform for simplified, standardized and reproducible microbiome data analysis","volume":"34","author":"Weber","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.psj.2022.101858_bib0074","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/S0741-5214(99)70329-0","article-title":"Heat shock proteins: a review of the molecular chaperones","volume":"29","author":"Whitley","year":"1999","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.psj.2022.101858_bib0075","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.3382\/ps.2011-01353","article-title":"Effects of dietary supplementation of methionine and its hydroxy analog DL-2-hydroxy-4-methylthiobutanoic acid on growth performance, plasma hormone levels, and the redox status of broiler chickens exposed to high temperatures","volume":"90","author":"Willemsen","year":"2011","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0076","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.3382\/ps\/pev105","article-title":"Effects of acute and chronic heat stress on plasma metabolites, hormones and oxidant status in restrictedly fed broiler breeders","volume":"94","author":"Xie","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0077","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1007\/s12192-019-01029-4","article-title":"Co-enzyme Q10 protects primary chicken myocardial cells from heat stress by upregulating autophagy and suppressing the PI3K\/AKT\/mTOR pathway","volume":"24","author":"Xu","year":"2019","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.psj.2022.101858_bib0078","doi-asserted-by":"crossref","first-page":"412","DOI":"10.3382\/ps\/pex297","article-title":"Short-chain arabinoxylans prepared from enzymatically treated wheat grain exert prebiotic effects during the broiler starter period","volume":"97","author":"Yacoubi","year":"2018","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0079","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.1016\/j.psj.2020.08.051","article-title":"Bacillus subtilis-based probiotic promotes bone growth by inhibition of inflammation in broilers subjected to cyclic heating episodes","volume":"99","author":"Yan","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.101858_bib0080","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3390\/nu12020381","article-title":"Role of dietary nutrients in the modulation of gut microbiota: a narrative review","volume":"12","author":"Yang","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.psj.2022.101858_bib0081","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s10753-013-9761-5","article-title":"Selenium inhibits LPS-induced pro-inflammatory gene expression by modulating MAPK and NF-\u03baB signaling pathways in mouse mammary epithelial cells in primary culture","volume":"37","author":"Zhang","year":"2014","journal-title":"Inflammation"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579122001651?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579122001651?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:42:30Z","timestamp":1758494550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579122001651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":81,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S0032579122001651"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2022.101858","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of dietary vitamin E and selenium supplementation on broilers subjected to heat stress, Part II: oxidative stress, immune response, gut integrity, and intestinal microbiota","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2022.101858","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"101858"}}