{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:18:28Z","timestamp":1785460708610,"version":"3.56.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T00:00:00Z","timestamp":1658361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.psj.2022.102078","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T12:37:20Z","timestamp":1658839040000},"page":"102078","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy of recombinant Newcastle disease virus expressing HA protein of H9N2 Avian influenza virus in respiratory and intestinal tract"],"prefix":"10.1016","volume":"101","author":[{"given":"Guanming","family":"Shao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyi","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wencheng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingmei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2022.102078_bib0001","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.vetmic.2018.04.009","article-title":"Enhanced infection of avian influenza virus H9N2 with infectious laryngeotracheitis vaccination in chickens","volume":"219","author":"Arafat","year":"2018","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2022.102078_bib0002","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.resp.2012.05.020","article-title":"Tight junctions, tight junction proteins and paracellular permeability across the gill epithelium of fishes: a review","volume":"184","author":"Chasiotis","year":"2012","journal-title":"Respir Physiol. Neurobiol."},{"key":"10.1016\/j.psj.2022.102078_bib0003","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0140-6736(14)60111-2","article-title":"Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study","volume":"383","author":"Chen","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.psj.2022.102078_bib0004","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.antiviral.2011.04.007","article-title":"Immune responses of chickens inoculated with a recombinant fowlpox vaccine coexpressing HA of H9N2 avain influenza virus and chicken IL-18","volume":"91","author":"Chen","year":"2011","journal-title":"Antiviral Res."},{"key":"10.1016\/j.psj.2022.102078_bib0005","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s42523-021-00128-x","article-title":"Low pathogenic avian influenza virus infection retards colon microbiota diversification in two different chicken lines","volume":"3","author":"Chrzastek","year":"2021","journal-title":"Anim. Microbiome."},{"key":"10.1016\/j.psj.2022.102078_bib0006","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1099\/0022-1317-80-1-131","article-title":"Complete nucleotide sequence of Newcastle disease virus: evidence for the existence of a new genus within the subfamily Paramyxovirinae","volume":"80","author":"de Leeuw","year":"1999","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.psj.2022.102078_bib0007","article-title":"Newcastle disease virus vectored bivalent vaccine against virulent infectious bursal disease and Newcastle disease of chickens","volume":"5","author":"Dey","year":"2017","journal-title":"Vaccines (Basel)"},{"key":"10.1016\/j.psj.2022.102078_bib0008","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.2217\/fmb.13.81","article-title":"Avian influenza: virology, diagnosis and surveillance","volume":"8","author":"El","year":"2013","journal-title":"Fut. Microbiol."},{"key":"10.1016\/j.psj.2022.102078_bib0009","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13567-017-0453-2","article-title":"Current situation of H9N2 subtype avian influenza in China","volume":"48","author":"Gu","year":"2017","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2022.102078_bib0010","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1637\/10972-110714-Reg","article-title":"Replication of an H9N2 avian influenza virus and cytokine gene expression in chickens exposed by aerosol or intranasal routes","volume":"59","author":"Guan","year":"2015","journal-title":"Avian Dis"},{"key":"10.1016\/j.psj.2022.102078_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2019.197648","article-title":"Utilization of herpesviridae as recombinant viral vectors in vaccine development against animal pathogens","volume":"270","author":"Kamel","year":"2019","journal-title":"Virus Res"},{"key":"10.1016\/j.psj.2022.102078_bib0012","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.dci.2013.04.012","article-title":"Immune responses of poultry to Newcastle disease virus","volume":"41","author":"Kapczynski","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.psj.2022.102078_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2019.104074","article-title":"Genetic characterization and pathogenesis of the first H9N2 low pathogenic avian influenza viruses isolated from chickens in Kenyan live bird markets","volume":"78","author":"Kariithi","year":"2020","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.psj.2022.102078_bib0014","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1637\/aviandiseases-D-21-00015","article-title":"Protective efficacy evaluation of four inactivated commercial vaccines against low pathogenic avian influenza H9N2 virus under experimental conditions in broiler chickens","volume":"65","author":"Khantour","year":"2021","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2022.102078_bib0015","doi-asserted-by":"crossref","DOI":"10.3390\/v8070183","article-title":"Newcastle disease virus as a vaccine vector for development of human and veterinary vaccines","volume":"8","author":"Kim","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.psj.2022.102078_bib0016","article-title":"Infectious bronchitis virus infection increases pathogenicity of H9N2 avian influenza virus by inducing severe inflammatory response","volume":"8","author":"Kong","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2022.102078_bib0017","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrd4529","article-title":"Advances in the development of influenza virus vaccines","volume":"14","author":"Krammer","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.psj.2022.102078_bib0018","article-title":"Live recombinant NDV-vectored H5 vaccine protects chickens and domestic ducks from lethal infection of the highly pathogenic H5N6 avian influenza virus","volume":"8","author":"Lee","year":"2021","journal-title":"Front. Vet.Sci."},{"key":"10.1016\/j.psj.2022.102078_bib0019","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.virol.2005.06.025","article-title":"Evolution of H9N2 influenza viruses from domestic poultry in Mainland China","volume":"340","author":"Li","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.psj.2022.102078_bib0020","doi-asserted-by":"crossref","DOI":"10.3390\/v10050270","article-title":"Avian influenza virus subtype H9N2 affects intestinal microbiota, barrier structure injury, and inflammatory intestinal disease in the chicken ileum","volume":"10","author":"Li","year":"2018","journal-title":"Viruses"},{"key":"10.1016\/j.psj.2022.102078_bib0025","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1637\/11452-061616-Reg","article-title":"Endemic variation of H9N2 avian influenza virus in China","volume":"60","author":"Liu","year":"2016","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2022.102078_bib0022","doi-asserted-by":"crossref","first-page":"34623","DOI":"10.1038\/srep34623","article-title":"Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster in Bacillus subtilis via Red\/ET recombineering","volume":"6","author":"Liu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2022.102078_bib0021","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.virol.2019.01.004","article-title":"Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza","volume":"529","author":"Liu","year":"2019","journal-title":"Virology"},{"key":"10.1016\/j.psj.2022.102078_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2019.109992","article-title":"Transcriptomic profile of chicken bone marrow-derive dendritic cells in response to H9N2 avian influenza A virus","volume":"220","author":"Liu","year":"2020","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2022.102078_bib0024","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1111\/tbed.13515","article-title":"Control of avian influenza in China: strategies and lessons","volume":"67","author":"Liu","year":"2020","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.psj.2022.102078_bib0026","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.3201\/eid2407.172059","article-title":"Avian influenza A virus infection among workers at live poultry markets, China, 2013-2016","volume":"24","author":"Ma","year":"2018","journal-title":"Emerg. Infect. Dis"},{"key":"10.1016\/j.psj.2022.102078_bib0027","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.meegid.2015.06.004","article-title":"Evolutionary trajectories and diagnostic challenges of potentially zoonotic avian influenza viruses H5N1 and H9N2 co-circulating in Egypt","volume":"34","author":"Naguib","year":"2015","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.psj.2022.102078_bib0028","doi-asserted-by":"crossref","DOI":"10.3390\/v11070620","article-title":"A global perspective on H9N2 avian influenza virus","volume":"11","author":"Peacock","year":"2019","journal-title":"Viruses"},{"key":"10.1016\/j.psj.2022.102078_bib0029","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1743-422X-9-61","article-title":"Systemic virus distribution and host responses in brain and intestine of chickens infected with low pathogenic or high pathogenic avian influenza virus","volume":"9","author":"Post","year":"2012","journal-title":"Virol J"},{"key":"10.1016\/j.psj.2022.102078_bib0030","article-title":"Single-dose vaccination of recombinant chimeric Newcastle Disease Virus (NDV) LaSota vaccine strain expressing infectious bursal disease virus (IBDV) VP2 gene provides full protection against genotype VII NDV and IBDV challenge","volume":"9","author":"Qiao","year":"2021","journal-title":"Vaccines (Basel)"},{"key":"10.1016\/j.psj.2022.102078_bib0031","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens8030145","article-title":"Recombinant Newcastle Disease Virus (NDV) expressing sigma C protein of avian reovirus (ARV) protects against both ARV and NDV in chickens","volume":"8","author":"Saikia","year":"2019","journal-title":"Pathogens"},{"key":"10.1016\/j.psj.2022.102078_bib0032","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s13238-014-0111-7","article-title":"H9N2 influenza virus in China: a cause of concern","volume":"6","author":"Sun","year":"2015","journal-title":"Protein Cell"},{"key":"10.1016\/j.psj.2022.102078_bib0033","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00018-012-1070-x","article-title":"Regulation of intestinal epithelial permeability by tight junctions","volume":"70","author":"Suzuki","year":"2013","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.psj.2022.102078_bib0034","first-page":"61","article-title":"Pathogenicity of avian influenza viruses in poultry","volume":"124","author":"Swayne","year":"2006","journal-title":"Dev. Biol. (Basel)"},{"key":"10.1016\/j.psj.2022.102078_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2015.10.031","article-title":"Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009-2013 and selection of a candidate vaccine strain with broad cross-reactivity","volume":"182","author":"Wei","year":"2016","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2022.102078_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0171564","article-title":"Genetic and antigenic evolution of H9N2 subtype avian influenza virus in domestic chickens in southwestern China, 2013-2016","volume":"12","author":"Xia","year":"2017","journal-title":"Plos One"},{"key":"10.1016\/j.psj.2022.102078_bib0037","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.3382\/ps\/pez255","article-title":"Generation and evaluation of a recombinant goose origin Newcastle disease virus expressing Cap protein of goose origin avastrovirus as a bivalent vaccine in goslings","volume":"98","author":"Xu","year":"2019","journal-title":"Poult Sci"},{"key":"10.1016\/j.psj.2022.102078_bib0038","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.vetmic.2018.11.006","article-title":"A novel recombinant attenuated Newcastle disease virus expressing H9 subtype hemagglutinin protected chickens from challenge by genotype VII virulent Newcastle disease virus and H9N2 avian influenza virus","volume":"228","author":"Xu","year":"2019","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2022.102078_bib0039","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3920\/BM2017.0088","article-title":"Gut microbiota modulates type I interferon and antibody-mediated immune responses in chickens infected with influenza virus subtype H9N2","volume":"9","author":"Yitbarek","year":"2018","journal-title":"Benef. Microbes"},{"key":"10.1016\/j.psj.2022.102078_bib0040","doi-asserted-by":"crossref","first-page":"13189","DOI":"10.1038\/s41598-018-31613-0","article-title":"Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses","volume":"8","author":"Yitbarek","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2022.102078_bib0041","doi-asserted-by":"crossref","DOI":"10.3390\/v13081606","article-title":"Generation and evaluation of recombinant thermostable Newcastle disease virus expressing the HA of H9N2 avian influenza virus","volume":"13","author":"Zhang","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.psj.2022.102078_bib0042","article-title":"Effect of baicalin on bacterial secondary infection and inflammation caused by H9N2 AIV infection in chickens","volume":"2020","author":"Zhang","year":"2020","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.psj.2022.102078_bib0043","article-title":"Nitrate is crucial for the proliferation of Gut Escherichia coli caused by H9N2 AIV infection and effective regulation by Chinese herbal medicine ageratum-liquid","volume":"11","author":"Zhang","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2022.102078_bib0044","article-title":"Genetic and biological characterization of H9N2 avian influenza viruses isolated in China from 2011 to 2014","volume":"13","author":"Zhu","year":"2018","journal-title":"Plos One"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579122003698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579122003698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:47:39Z","timestamp":1758494859000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579122003698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S0032579122003698"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2022.102078","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of recombinant Newcastle disease virus expressing HA protein of H9N2 Avian influenza virus in respiratory and intestinal tract","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2022.102078","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"102078"}}