{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:33:06Z","timestamp":1785515586305,"version":"3.56.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012428","name":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences","doi-asserted-by":"publisher","award":["Y2022GH02"],"award-info":[{"award-number":["Y2022GH02"]}],"id":[{"id":"10.13039\/501100012428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005196","name":"Chinese Academy of Agricultural Sciences","doi-asserted-by":"publisher","award":["CAAS-ZDRW202006-02"],"award-info":[{"award-number":["CAAS-ZDRW202006-02"]}],"id":[{"id":"10.13039\/501100005196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011364","name":"National Key Laboratory of Animal Nutrition","doi-asserted-by":"publisher","award":["2004DA125184G2202"],"award-info":[{"award-number":["2004DA125184G2202"]}],"id":[{"id":"10.13039\/501100011364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.psj.2022.102221","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T02:03:28Z","timestamp":1664849008000},"page":"102221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Long-term chemically protected sodium butyrate supplementation in broilers as an antibiotic alternative to dynamically modulate gut microbiota"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3749-3887","authenticated-orcid":false,"given":"F.","family":"Wan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.L.","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.Q.","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.Y.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.B.","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.F.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2022.102221_bib0001","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.scitotenv.2019.02.270","article-title":"Impacts of rare earth elements on animal health and production: highlights of cerium and lanthanum","volume":"672","author":"Abdelnour","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2022.102221_bib0002","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00018-018-2943-4","article-title":"An insight into gut microbiota and its functionalities","volume":"76","author":"Adak","year":"2019","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0003","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.fct.2019.01.033","article-title":"Importance of antibiotic residues in animal food","volume":"125","author":"Bacanli","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.psj.2022.102221_bib0004","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1093\/ecco-jcc\/jjaa065","article-title":"Gut microbiota-derived propionate regulates the expression of Reg3 mucosal lectins and ameliorates experimental colitis in mice","volume":"14","author":"Bajic","year":"2020","journal-title":"J. Crohns Colitis."},{"key":"10.1016\/j.psj.2022.102221_bib0005","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1161\/CIRCULATIONAHA.118.036652","article-title":"Short-chain fatty acid propionate protects from hypertensive cardiovascular damage","volume":"139","author":"Bartolomaeus","year":"2019","journal-title":"Circulation."},{"key":"10.1016\/j.psj.2022.102221_bib0006","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1089\/mdr.2019.0442","article-title":"Antibiotic resistance in escherichia coli from broiler chickens after amoxicillin treatment in an experimental environment","volume":"26","author":"Burow","year":"2020","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.psj.2022.102221_bib0007","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.bbalip.2016.06.016","article-title":"Malondialdehyde epitopes as mediators of sterile inflammation","volume":"1862","author":"Busch","year":"2017","journal-title":"Biochim. Biophys. Acta. Mol. Cell Biol. Lipids."},{"key":"10.1016\/j.psj.2022.102221_bib0008","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s13071-020-3897-6","article-title":"Dissection of the cecal microbial community in chickens after Eimeria tenella infection","volume":"13","author":"Chen","year":"2020","journal-title":"Parasit. Vectors."},{"key":"10.1016\/j.psj.2022.102221_bib0009","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-035677","article-title":"Antibiotic-induced changes in the human gut microbiota for the most commonly prescribed antibiotics in primary care in the UK: a systematic review","volume":"10","author":"Elvers","year":"2020","journal-title":"BMJ Open."},{"key":"10.1016\/j.psj.2022.102221_bib0010","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1007\/s10096-019-03580-5","article-title":"Antibiotic resistance genes in the Actinobacteria phylum","volume":"38","author":"Fatahi-Bafghi","year":"2019","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.psj.2022.102221_bib0011","doi-asserted-by":"crossref","first-page":"3937","DOI":"10.3382\/ps\/pez129","article-title":"Influence of beak trimming and inclusion of sodium butyrate in the diet on growth performance and digestive tract traits of brown-egg pullets differing in initial body weight","volume":"98","author":"Garcia","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0012","doi-asserted-by":"crossref","first-page":"e00012","DOI":"10.1128\/IAI.00012-20","article-title":"Antibiotic degradation by commensal microbes shields pathogens","volume":"88","author":"Gjonbalaj","year":"2020","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psj.2022.102221_bib0013","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1093\/eurheartj\/ehab644","article-title":"Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism","volume":"43","author":"Haghikia","year":"2022","journal-title":"Eur. Heart. J."},{"key":"10.1016\/j.psj.2022.102221_bib0014","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s40104-020-00492-9","article-title":"Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets","volume":"11","author":"Hu","year":"2020","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122813","article-title":"Recognition of typical antibiotic residues in environmental media related to groundwater in China (2009-2019)","volume":"399","author":"Huang","year":"2020","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.psj.2022.102221_bib0016","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1099\/mic.0.040618-0","article-title":"Long-term impacts of antibiotic exposure on the human intestinal microbiota","volume":"156","author":"Jernberg","year":"2010","journal-title":"Microbiology (Reading)."},{"key":"10.1016\/j.psj.2022.102221_bib0017","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/nri3430","article-title":"Role of the gut microbiota in immunity and inflammatory disease","volume":"13","author":"Kamada","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psj.2022.102221_bib0018","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3390\/nu13020389","article-title":"Gut-brain-microbiota axis: antibiotics and functional gastrointestinal disorders","volume":"13","author":"Karakan","year":"2021","journal-title":"Nutrients."},{"key":"10.1016\/j.psj.2022.102221_bib0019","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s13054-016-1320-7","article-title":"Antibiotic strategies in the era of multidrug resistance","volume":"20","author":"Karam","year":"2016","journal-title":"Crit. Care."},{"key":"10.1016\/j.psj.2022.102221_bib0020","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s40104-020-0433-7","article-title":"Salmonella Typhimurium infection disrupts but continuous feeding of Bacillus based probiotic restores gut microbiota in infected hens","volume":"11","author":"Khan","year":"2020","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0021","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s40104-021-00606-x","article-title":"Dietary sophorolipid accelerates growth by modulation of gut microbiota population and intestinal environments in broiler chickens","volume":"12","author":"Kwak","year":"2021","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0022","doi-asserted-by":"crossref","first-page":"5491","DOI":"10.1016\/j.psj.2020.06.042","article-title":"Sodium butyrate as an effective feed additive to improve performance, liver function, and meat quality in broilers under hot climatic conditions","volume":"99","author":"Lan","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0023","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.brainresbull.2020.12.009","article-title":"Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1\/Nrf2\/HO-1 pathway","volume":"168","author":"Li","year":"2021","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.psj.2022.102221_bib0024","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3389\/fphar.2018.00533","article-title":"The Anti-inflammatory effects of short chain fatty acids on lipopolysaccharide- or tumor necrosis factor alpha-stimulated endothelial cells via activation of GPR41\/43 and inhibition of HDACs","volume":"9","author":"Li","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.psj.2022.102221_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.152756","article-title":"Occurrence and distribution of antibiotics and antibiotic resistance genes in the guts of shrimp from different coastal areas of China","volume":"815","author":"Li","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2022.102221_bib0026","doi-asserted-by":"crossref","first-page":"4114","DOI":"10.1007\/s00284-020-02240-8","article-title":"Study on the diversity and function of gut microbiota in pigs following long-term antibiotic and antibiotic-free breeding","volume":"77","author":"Li","year":"2020","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.psj.2022.102221_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109249","article-title":"Cancer and ER stress: Mutual crosstalk between autophagy, oxidative stress and inflammatory response","volume":"118","author":"Lin","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.psj.2022.102221_bib0028","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1096\/fj.201801221RR","article-title":"Microbial and metabolic alterations in gut microbiota of sows during pregnancy and lactation","volume":"33","author":"Liu","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.psj.2022.102221_bib0029","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1021\/jf403288r","article-title":"Oral administration of Lactobacillus fermentum I5007 favors intestinal development and alters the intestinal microbiota in formula-fed piglets","volume":"62","author":"Liu","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2022.102221_bib0030","doi-asserted-by":"crossref","first-page":"4217","DOI":"10.1016\/j.psj.2020.05.011","article-title":"Forsythia suspensa extract enhances performance via the improvement of nutrient digestibility, antioxidant status, anti-inflammatory function, and gut morphology in broilers","volume":"99","author":"Long","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0031","doi-asserted-by":"crossref","first-page":"e00134","DOI":"10.1128\/mSystems.00134-17","article-title":"Fecal microbiota transplantation in gestating sows and neonatal offspring alters lifetime intestinal microbiota and growth in offspring","volume":"3","author":"McCormack","year":"2018","journal-title":"mSystems."},{"key":"10.1016\/j.psj.2022.102221_bib0032","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.freeradbiomed.2018.03.042","article-title":"Hypoxia, oxidative stress and inflammation","volume":"125","author":"McGarry","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.psj.2022.102221_bib0033","doi-asserted-by":"crossref","first-page":"100392","DOI":"10.3390\/ijms221910392","article-title":"Butyric and citric acids and their salts in poultry nutrition: effects on gut health and intestinal microbiota","volume":"22","author":"Melaku","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0034","doi-asserted-by":"crossref","first-page":"9277","DOI":"10.1007\/s00253-019-10165-x","article-title":"Antibiotic effects on gut microbiota, metabolism, and beyond","volume":"103","author":"Mu","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0035","doi-asserted-by":"crossref","first-page":"906","DOI":"10.3389\/fimmu.2020.00906","article-title":"The genus alistipes: gut bacteria with emerging implications to inflammation, cancer, and mental health","volume":"11","author":"Parker","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2022.102221_bib0036","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1038\/ismej.2016.77","article-title":"Phylogenetic network analysis applied to pig gut microbiota identifies an ecosystem structure linked with growth traits","volume":"10","author":"Ramayo-Caldas","year":"2016","journal-title":"ISME J."},{"key":"10.1016\/j.psj.2022.102221_bib0037","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2020.572912","article-title":"Antibiotics as major disruptors of gut microbiota","volume":"10","author":"Ramirez","year":"2020","journal-title":"Front. Cell Infect. Microbiol."},{"key":"10.1016\/j.psj.2022.102221_bib0038","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13099-021-00467-9","article-title":"Influence of lincomycin-spectinomycin treatment on the outcome of Enterococcus cecorum infection and on the cecal microbiota in broilers","volume":"14","author":"Schreier","year":"2022","journal-title":"Gut. Pathog."},{"key":"10.1016\/j.psj.2022.102221_bib0039","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s13073-020-00782-x","article-title":"Understanding the impact of antibiotic perturbation on the human microbiome","volume":"12","author":"Schwartz","year":"2020","journal-title":"Genome Med."},{"key":"10.1016\/j.psj.2022.102221_bib0040","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jid.2020.04.031","article-title":"Induction of regulatory T cells and correction of cytokine disbalance by short-chain fatty acids: implications for psoriasis therapy","volume":"141","author":"Schwarz","year":"2021","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.psj.2022.102221_bib0041","doi-asserted-by":"crossref","first-page":"eaao4755","DOI":"10.1126\/scitranslmed.aao4755","article-title":"Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis","volume":"10","author":"Scott","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.psj.2022.102221_bib0042","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ecoenv.2019.04.018","article-title":"Phytotoxicity and degradation of antibiotic ofloxacin in duckweed (Spirodela polyrhiza) system","volume":"179","author":"Singh","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.psj.2022.102221_bib0043","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.3389\/fphar.2019.01030","article-title":"Protective effects of dioscin against doxorubicin-induced hepatotoxicity via regulation of sirt1\/FOXO1\/NF-kappab signal","volume":"10","author":"Song","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.psj.2022.102221_bib0044","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s40104-021-00644-5","article-title":"Resistant starch: implications of dietary inclusion on gut health and growth in pigs: a review","volume":"12","author":"Tan","year":"2021","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0045","doi-asserted-by":"crossref","first-page":"8441","DOI":"10.1007\/s00253-021-11627-x","article-title":"Time-course alterations of gut microbiota and short-chain fatty acids after short-term lincomycin exposure in young swine","volume":"105","author":"Tang","year":"2021","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.784211","article-title":"Caffeic acid supplement alleviates colonic inflammation and oxidative stress potentially through improved gut microbiota community in mice","volume":"12","author":"Wan","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2022.102221_bib0047","doi-asserted-by":"crossref","first-page":"128","DOI":"10.2141\/jpsa.0150077","article-title":"Effects of flavomycin, bacillus licheniformis and enramycin on performance, nutrient digestibility, gut morphology and the intestinal microflora of broilers","volume":"53","author":"Wang","year":"2016","journal-title":"J. Poult. Sci."},{"key":"10.1016\/j.psj.2022.102221_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125135","article-title":"Enhanced removal of antibiotic resistance genes and mobile genetic elements during swine manure composting inoculated with mature compost","volume":"411","author":"Wang","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.psj.2022.102221_bib0049","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1136\/gutjnl-2019-320105","article-title":"A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8(+) T cells in mice","volume":"69","author":"Wang","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.psj.2022.102221_bib0050","doi-asserted-by":"crossref","first-page":"11648","DOI":"10.1073\/pnas.1917597117","article-title":"Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin","volume":"117","author":"Wang","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.psj.2022.102221_bib0051","article-title":"Dietary sodium butyrate improves intestinal development and function by modulating the microbial community in broilers","volume":"13","author":"Wu","year":"2018","journal-title":"PLoS One."},{"key":"10.1016\/j.psj.2022.102221_bib0052","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s40168-022-01326-8","article-title":"Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model","volume":"10","author":"Xia","year":"2022","journal-title":"Microbiome."},{"key":"10.1016\/j.psj.2022.102221_bib0053","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s13568-021-01274-w","article-title":"The varying effects of antibiotics on gut microbiota","volume":"11","author":"Yang","year":"2021","journal-title":"AMB Express."},{"key":"10.1016\/j.psj.2022.102221_bib0054","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40104-021-00663-2","article-title":"Butyrate in combination with forskolin alleviates necrotic enteritis, increases feed efficiency, and improves carcass composition of broilers","volume":"13","author":"Yang","year":"2022","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2022.102221_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104506","article-title":"To resist and persist: Important factors in the pathogenesis of Bacteroides fragilis","volume":"149","author":"Yekani","year":"2020","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.psj.2022.102221_bib0056","doi-asserted-by":"crossref","DOI":"10.1016\/j.resmic.2021.103798","article-title":"Tightly controlled response to oxidative stress; an important factor in the tolerance of Bacteroides fragilis","volume":"172","author":"Yekani","year":"2021","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.psj.2022.102221_bib0057","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3390\/antibiotics9120907","article-title":"Short-term lincomycin exposure depletion of murine microbiota affects short-chain fatty acids and intestinal morphology and immunity","volume":"9","author":"Zhang","year":"2020","journal-title":"Antibiotics (Basel)."},{"key":"10.1016\/j.psj.2022.102221_bib0058","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3390\/metabo11080487","article-title":"Antibiotic-induced dysbiosis of microbiota promotes chicken lipogenesis by altering metabolomics in the cecum","volume":"11","author":"Zhang","year":"2021","journal-title":"Metabolites."},{"key":"10.1016\/j.psj.2022.102221_bib0059","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3390\/antibiotics11020132","article-title":"Chemically protected sodium butyrate improves growth performance and early development and function of small intestine in broilers as one effective substitute for antibiotics","volume":"11","author":"Zhao","year":"2022","journal-title":"Antibiotics."},{"key":"10.1016\/j.psj.2022.102221_bib0060","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.redox.2017.12.013","article-title":"MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2","volume":"15","author":"Zhao","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.psj.2022.102221_bib0061","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.3382\/ps\/pez279","article-title":"Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers","volume":"98","author":"Zou","year":"2019","journal-title":"Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912200517X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912200517X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:49:21Z","timestamp":1758494961000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003257912200517X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":61,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S003257912200517X"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2022.102221","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term chemically protected sodium butyrate supplementation in broilers as an antibiotic alternative to dynamically modulate gut microbiota","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2022.102221","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"102221"}}