{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:16:51Z","timestamp":1761808611992,"version":"3.44.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.psj.2023.102802","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T01:58:09Z","timestamp":1684893489000},"page":"102802","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mortality, growth, and egg production do not differ between nontransgenic and transgenic female chickens with ubiquitous expression of the 3D8 single chain variable fragment gene"],"prefix":"10.1016","volume":"102","author":[{"given":"Hyeon","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun A.","family":"Ock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seunghoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Ryung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seokho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingu","family":"No","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keon Bong","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayeon","family":"Wi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Keun","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Jin","family":"Jo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0537-6205","authenticated-orcid":false,"given":"Bo Ram","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minguk","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung June","family":"Byun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2023.102802_bib0001","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3923\/ajpsaj.2014.82.96","article-title":"Influence of different levels of certain essential amino acids on the performance, egg quality criteria and economics of Lohmann Brown laying hens","volume":"8","author":"Alagawany","year":"2014","journal-title":"Asian J. Poult. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0002","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/s41467-020-20812-x","article-title":"Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating","volume":"12","author":"Ballantyne","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2023.102802_bib0003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0131088","article-title":"Genetic and non-genetic inheritance of natural antibodies binding keyhole limpet hemocyanin in a purebred layer chicken line","volume":"10","author":"Berghof","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2023.102802_bib0005","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1186\/s12917-020-02462-9","article-title":"The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickens","volume":"16","author":"Byun","year":"2020","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2023.102802_bib0004","doi-asserted-by":"crossref","first-page":"5938","DOI":"10.1038\/s41598-017-05270-8","article-title":"Transgenic chickens expressing the 3D8 single chain variable fragment protein suppress avian influenza transmission","volume":"7","author":"Byun","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2023.102802_bib0006","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.omtn.2017.04.001","article-title":"CRISPR\/Cas9: transcending the reality of genome editing","volume":"7","author":"Chira","year":"2017","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.psj.2023.102802_bib0007","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3390\/vetsci9040182","article-title":"Influence of dietary supplementation with Boswellia serrata and Salix alba on performance and blood biochemistry in free-range Leghorn laying hens","volume":"9","author":"Guerrini","year":"2022","journal-title":"Vet. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.animal.2021.100199","article-title":"Effects of rearing systems on production performance, antioxidant capacity and immune status of meat ducks at different ages","volume":"15","author":"Guo","year":"2021","journal-title":"Animal"},{"key":"10.1016\/j.psj.2023.102802_bib0009","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1007\/s00253-014-6257-7","article-title":"Development of Lactobacillus paracasei harboring nucleic acid-hydrolyzing 3D8 scFv as a preventive probiotic against murine norovirus infection","volume":"99","author":"Hoang","year":"2015","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2023.102802_bib0010","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1007\/s00018-009-9179-2","article-title":"A nucleic acid-hydrolyzing antibody penetrates into cells via caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity","volume":"66","author":"Jang","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0011","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbrc.2010.04.032","article-title":"An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus","volume":"395","author":"Jun","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.psj.2023.102802_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.627714","article-title":"Recent advances in the application of CRISPR\/Cas9 gene editing system in poultry species","volume":"12","author":"Khwatenge","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.psj.2023.102802_bib0013","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1096\/fj.201903035R","article-title":"Generation of myostatin-knockout chickens mediated by D10A-Cas9 nickase","volume":"34","author":"Kim","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.psj.2023.102802_bib0014","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s12257-016-0590-x","article-title":"Production of transgenic chickens constitutively expressing human erythropoietin (hEPO): problems with uncontrollable overexpression of hEPO gene","volume":"22","author":"Koo","year":"2017","journal-title":"Biotechnol. Bioprocess Eng."},{"key":"10.1016\/j.psj.2023.102802_bib0016","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.rvsc.2019.01.025","article-title":"The 3D8 single chain variable fragment protein suppress infectious bronchitis virus transmission in the transgenic chickens","volume":"123","author":"Lee","year":"2019","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0017","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.3390\/ijms21041504","article-title":"Muscle hyperplasia in japanese quail by single amino acid deletion in MSTN propeptide","volume":"21","author":"Lee","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004208","article-title":"A nucleic-acid hydrolyzing single chain antibody confers resistance to DNA virus infection in hela cells and C57BL\/6 mice","volume":"10","author":"Lee","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.psj.2023.102802_bib0018","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1126\/science.1198020","article-title":"Suppression of avian influenza transmission in genetically modified chickens","volume":"331","author":"Lyall","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.psj.2023.102802_bib0019","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1017\/S0043933916000246","article-title":"The potential for using enzymatic assays to assess the health of turkeys","volume":"72","author":"Ognik","year":"2016","journal-title":"Worlds Poult. Sci. J."},{"key":"10.1016\/j.psj.2023.102802_bib0020","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.3382\/ps.2012-02277","article-title":"Egg production curve fitting using nonlinear models for selected and nonselected lines of White Leghorn hens","volume":"91","author":"Savegnago","year":"2012","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0021","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nbt0216-117","article-title":"FDA approves 'farmaceutical' drug from transgenic chickens","volume":"34","author":"Sheridan","year":"2016","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.psj.2023.102802_bib0022","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s13205-019-1811-8","article-title":"Oral administration of Lactobacillus reuteri expressing a 3D8 single-chain variable fragment (scFv) enhances chicken growth and conserves immune homeostasis","volume":"9","author":"Sureshkumar","year":"2019","journal-title":"3 Biotech."},{"key":"10.1016\/j.psj.2023.102802_bib0023","doi-asserted-by":"crossref","first-page":"e13399","DOI":"10.1111\/asj.13399","article-title":"Administration of L. salivarius expressing 3D8 scFv as a feed additive improved the growth performance, immune homeostasis, and gut microbiota of chickens","volume":"91","author":"Sureshkumar","year":"2020","journal-title":"Anim. Sci. J."},{"key":"10.1016\/j.psj.2023.102802_bib0024","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00203-020-02088-3","article-title":"Inclusion of Lactobacillus salivarius strain revealed a positive effect on improving growth performance, fecal microbiota and immunological responses in chicken","volume":"203","author":"Sureshkumar","year":"2021","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.psj.2023.102802_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/1806-9061-2022-1640","article-title":"Preliminary study to investigate the effect of Lactobacillus reuteri administration on growth performance, immunological, gut microbiome and intestinal mucosa of chicken","volume":"24","author":"Sureshkumar","year":"2022","journal-title":"Braz. J. Poult. Sci."},{"key":"10.1016\/j.psj.2023.102802_bib0026","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1186\/s12917-017-1160-y","article-title":"Performance, biochemical and haematological responses, and relative organ weights of laying hens fed diets supplemented with prebiotic, probiotic and synbiotic","volume":"13","author":"Tang","year":"2017","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2023.102802_bib0027","doi-asserted-by":"crossref","first-page":"20930","DOI":"10.1073\/pnas.1906316116","article-title":"Reviving rare chicken breeds using genetically engineered sterility in surrogate host birds","volume":"116","author":"Woodcock","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.psj.2023.102802_bib0028","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1007\/s12011-017-1232-7","article-title":"Dietary supplementation with chromium picolinate influences serum glucose and immune response of brown-egg laying hens","volume":"185","author":"Zhang","year":"2018","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2023.102802_bib0029","doi-asserted-by":"crossref","first-page":"e264","DOI":"10.1038\/mtna.2015.37","article-title":"Off-target effects in CRISPR\/Cas9-mediated genome engineering","volume":"4","author":"Zhang","year":"2015","journal-title":"Mol. Ther. Nucleic Acids"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579123003218?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579123003218?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T22:53:45Z","timestamp":1758495225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579123003218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0032579123003218"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2023.102802","relation":{},"ISSN":["0032-5791"],"issn-type":[{"type":"print","value":"0032-5791"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mortality, growth, and egg production do not differ between nontransgenic and transgenic female chickens with ubiquitous expression of the 3D8 single chain variable fragment gene","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2023.102802","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"102802"}}