{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T22:11:24Z","timestamp":1794262284011,"version":"4.9.0"},"reference-count":72,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012431","name":"Jiangsu Provincial Agricultural Science and Technology Independent Innovation Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012431","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007540","name":"Jiangsu Agricultural Science and Technology Innovation Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007540","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.psj.2023.103420","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T12:08:01Z","timestamp":1704802081000},"page":"103420","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Effects of puerarin as a feed additive on the laying performance, egg quality, endocrine hormones, antioxidant capacity, and intestinal morphology of aged laying hens"],"prefix":"10.1016","volume":"103","author":[{"given":"Xubin","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huifang","family":"Pian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4803-8580","authenticated-orcid":false,"given":"Debing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2023.103420_bib0001","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40104-016-0097-5","article-title":"Association between heat stress and oxidative stress in poultry; mitochondrial dysfunction and dietary interventions with phytochemicals","volume":"7","author":"Akbarian","year":"2016","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2023.103420_bib0002","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s40360-020-00426-1","article-title":"Natural dietary compound naringin inhibits glioblastoma cancer neoangiogenesis","volume":"21","author":"Aroui","year":"2020","journal-title":"BMC Pharmacol. Toxicol."},{"key":"10.1016\/j.psj.2023.103420_bib0003","doi-asserted-by":"crossref","first-page":"53","DOI":"10.5507\/bp.2013.096","article-title":"The anti-atherosclerotic effects of puerarin on induced-atherosclerosis in rabbits","volume":"159","author":"Bao","year":"2015","journal-title":"Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub."},{"key":"10.1016\/j.psj.2023.103420_bib0004","doi-asserted-by":"crossref","first-page":"980","DOI":"10.5713\/ajas.2000.980","article-title":"Influences of long-term feeding of Japanese green tea powder on laying performance and egg quality in hens","volume":"13","author":"Biswas","year":"2000","journal-title":"Asian-Australasian J. Anim. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0005","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1007\/s43032-020-00325-0","article-title":"protective effects of puerarin on premature ovarian failure via regulation of Wnt\/\u03b2-catenin signaling pathway and oxidative stress","volume":"28","author":"Chen","year":"2021","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0006","doi-asserted-by":"crossref","first-page":"e45529","DOI":"10.1371\/journal.pone.0045529","article-title":"Puerarin suppresses proliferation of endometriotic stromal cells partly via the MAPK signaling pathway induced by 17ss-estradiol-BSA","volume":"7","author":"Cheng","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2023.103420_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.791071","article-title":"Ovarian aging: role of pituitary-ovarian axis hormones and ncRNAs in regulating ovarian mitochondrial activity","volume":"12","author":"Colella","year":"2021","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.psj.2023.103420_bib0008","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1093\/ps\/81.11.1744","article-title":"Oxidative stability and sensory and functional properties of eggs from laying hens fed supranutritional doses of vitamins E and C","volume":"81","author":"Franchini","year":"2002","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0009","article-title":"Effects of Pueraria extract and curcumin on growth performance, antioxidant status and intestinal integrity of broiler chickens","volume":"13","author":"Guo","year":"2023","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.psj.2023.103420_bib0010","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1016\/j.psj.2019.11.040","article-title":"Melatonin regulates the ovarian function and enhances follicle growth in aging laying hens via activating the mammalian target of rapamycin pathway","volume":"99","author":"Hao","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.641696","article-title":"Immunostimulatory potential of fruits and their extracts in poultry","volume":"12","author":"Hasted","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2023.103420_bib0012","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1439-0396.2012.01284.x","article-title":"Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds","volume":"97","author":"Heo","year":"2013","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.psj.2023.103420_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101217","article-title":"Effect of phloretin on growth performance, serum biochemical parameters and antioxidant profile in heat-stressed broilers","volume":"100","author":"Hu","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0014","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jsbmb.2006.06.020","article-title":"Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration","volume":"101","author":"Hwang","year":"2006","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.psj.2023.103420_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.109847","article-title":"Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model","volume":"124","author":"Jeon","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.psj.2023.103420_bib0016","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3382\/ps.2013-03384","article-title":"Performance, serum biochemical responses, and gene expression of intestinal folate transporters of young and older laying hens in response to dietary folic acid supplementation and challenge with Escherichia coli lipopolysaccharide","volume":"93","author":"Jing","year":"2014","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0017","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.52586\/5058","article-title":"Puerarin-an isoflavone with beneficial effects on bone health","volume":"26","author":"Kulczynski","year":"2021","journal-title":"Front. Biosci. (Landmark Ed)"},{"key":"10.1016\/j.psj.2023.103420_bib0018","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.bbrc.2018.03.018","article-title":"The suppressive effect of puerarin on atopic dermatitis-like skin lesions through regulation of inflammatory mediators in vitro and in vivo","volume":"498","author":"Lee","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.psj.2023.103420_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110923","article-title":"Puerarin improves the bone micro-environment to inhibit OVX-induced osteoporosis via modulating SCFAs released by the gut microbiota and repairing intestinal mucosal integrity","volume":"132","author":"Li","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.psj.2023.103420_bib0020","article-title":"The adiponectin receptor agonist, AdipoRon, promotes reproductive hormone secretion and gonadal development via the hypothalamic-pituitary-gonadal axis in chickens","volume":"102","author":"Li","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0021","article-title":"Effects of dietary rutin supplementation on the intestinal morphology, antioxidant capacity, immunity, and microbiota of aged laying hens","volume":"11","author":"Li","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.psj.2023.103420_bib0022","doi-asserted-by":"crossref","first-page":"e26049","DOI":"10.1097\/MD.0000000000026049","article-title":"Therapeutic effects of puerarin on polycystic ovary syndrome: a randomized trial in Chinese women","volume":"100","author":"Li","year":"2021","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.psj.2023.103420_bib0023","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.3382\/ps.0722005","article-title":"Age-dependent changes in oviposition pattern and egg production traits in the domestic hen","volume":"72","author":"Lillpers","year":"1993","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0024","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1210\/en.2015-1206","article-title":"Glutamate cysteine ligase modifier subunit (Gclm) null mice have increased ovarian oxidative stress and accelerated age-related ovarian failure","volume":"156","author":"Lim","year":"2015","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2023.103420_bib0025","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3382\/ps.2007-00274","article-title":"Effects of daidzein on messenger ribonucleic acid expression of gonadotropin receptors in chicken ovarian follicles","volume":"87","author":"Liu","year":"2008","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102674","article-title":"Comparison of the effect of quercetin and daidzein on production performance, anti-oxidation, hormones, and cecal microflora in laying hens during the late laying period","volume":"102","author":"Liu","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0027","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1016\/j.psj.2019.12.001","article-title":"Effect of curcumin on laying performance, egg quality, endocrine hormones, and immune activity in heat-stressed hens","volume":"99","author":"Liu","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0028","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.18632\/aging.101526","article-title":"Lycopene ameliorates oxidative stress in the aging chicken ovary via activation of Nrf2\/HO-1 pathway","volume":"10","author":"Liu","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.psj.2023.103420_bib0029","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1631\/jzus.B1700054","article-title":"Age-related changes of yolk precursor formation in the liver of laying hens","volume":"19","author":"Liu","year":"2018","journal-title":"J. Zhejiang Univ. Sci. B."},{"key":"10.1016\/j.psj.2023.103420_bib0030","doi-asserted-by":"crossref","first-page":"10832","DOI":"10.1038\/s41598-018-29162-7","article-title":"Genetic variations for egg quality of chickens at late laying period revealed by genome-wide association study","volume":"8","author":"Liu","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2023.103420_bib0031","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2023.103420_bib0032","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24097742","article-title":"Puerarin alleviates H2O2-induced oxidative stress and blood-milk barrier impairment in dairy cows","volume":"24","author":"Lyu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0033","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1007\/s12011-020-02398-z","article-title":"Epigallocatechin-3-gallate alleviates vanadium-induced reduction of antioxidant capacity via Keap1-Nrf2-sMaf pathway in the liver, kidney, and ovary of laying hens","volume":"199","author":"Ma","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2023.103420_bib0034","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/ptr.4676","article-title":"Effects of the total alkaloidal extract of Murraya koenigii leaf on oxidative stress and cholinergic transmission in aged mice","volume":"27","author":"Mani","year":"2013","journal-title":"Phytother. Res."},{"key":"10.1016\/j.psj.2023.103420_bib0035","doi-asserted-by":"crossref","DOI":"10.3390\/nu12061592","article-title":"Antidiabetic effects of Flavan-3-ols and their microbial metabolites","volume":"12","author":"Marquez Campos","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.psj.2023.103420_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2022.111707","article-title":"Oxidative stress, aging, antioxidant supplementation and their impact on human health: an overview","volume":"206","author":"Martemucci","year":"2022","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.psj.2023.103420_bib0037","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/humupd\/dmaa039","article-title":"Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies","volume":"27","author":"Meresman","year":"2021","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.psj.2023.103420_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106993","article-title":"Puerarin inhibits mycoplasma gallisepticum (MG-HS)-induced inflammation and apoptosis via suppressing the TLR6\/MyD88\/NF-kappaB signal pathway in chicken","volume":"88","author":"Niu","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.psj.2023.103420_bib0039","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41573-020-0067-7","article-title":"The quest to slow ageing through drug discovery","volume":"19","author":"Partridge","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.psj.2023.103420_bib0040","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1080\/10408398.2018.1486284","article-title":"Modulation of gastrointestinal barrier and nutrient transport function in farm animals by natural plant bioactive compounds - a comprehensive review","volume":"59","author":"Patra","year":"2019","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.psj.2023.103420_bib0041","doi-asserted-by":"crossref","first-page":"6266","DOI":"10.1038\/s41598-017-06552-x","article-title":"Puerarin ameliorated the behavioral deficits induced by chronic stress in rats","volume":"7","author":"Qiu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2023.103420_bib0042","doi-asserted-by":"crossref","DOI":"10.3390\/molecules22030477","article-title":"Flavonoids: from structure to health issues","volume":"22","author":"Santos-Buelga","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.psj.2023.103420_bib0043","doi-asserted-by":"crossref","first-page":"3606","DOI":"10.1093\/jn\/nxab309","article-title":"GlyNAC supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, aging hallmarks, metabolic defects, muscle strength, cognitive decline, and body composition: implications for healthy aging","volume":"151","author":"Sekhar","year":"2021","journal-title":"J. Nutr."},{"key":"10.1016\/j.psj.2023.103420_bib0044","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1039\/C3FO60565E","article-title":"Effects of puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-beta1\/Smad2 pathway","volume":"5","author":"She","year":"2014","journal-title":"Food Funct."},{"key":"10.1016\/j.psj.2023.103420_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.132531","article-title":"Plant flavonoids: classification, distribution, biosynthesis, and antioxidant activity","volume":"383","author":"Shen","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.psj.2023.103420_bib0046","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3389\/fvets.2020.00418","article-title":"Effect of the single and combined use of curcumin and piperine on growth performance, intestinal barrier function, and antioxidant capacity of weaned Wuzhishan piglets","volume":"7","author":"Shi","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0047","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1093\/ps\/80.8.1240","article-title":"Effect of storage and layer age on quality of eggs from two lines of hens","volume":"80","author":"Silversides","year":"2001","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0048","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.vetimm.2015.03.008","article-title":"Relationship of Salmonella infection and inflammatory intestinal response with hematological and serum biochemical values in laying hens","volume":"165","author":"Soria","year":"2015","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2023.103420_bib0049","doi-asserted-by":"crossref","first-page":"664","DOI":"10.3382\/ps\/pey415","article-title":"The development of antioxidant system in the intestinal tract of broiler chickens","volume":"98","author":"Tang","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0050","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s13659-023-00390-3","article-title":"Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier","volume":"13","author":"Tao","year":"2023","journal-title":"Nat. Prod. Bioprospect."},{"key":"10.1016\/j.psj.2023.103420_bib0051","doi-asserted-by":"crossref","first-page":"e99423","DOI":"10.1371\/journal.pone.0099423","article-title":"Effects of 5alpha-dihydrotestosterone and 17beta-estradiol on the mouse ovarian follicle development and oocyte maturation","volume":"9","author":"Tarumi","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2023.103420_bib0052","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4274\/tpd.galenos.2022.07088","article-title":"The importance of antioxidant enzymes and oxidative stress in human fascioliasis","volume":"47","author":"Tas Cengiz","year":"2023","journal-title":"Turk. Parazitol. Derg."},{"key":"10.1016\/j.psj.2023.103420_bib0053","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3945\/jn.110.135657","article-title":"Regulation of tight junction permeability by intestinal bacteria and dietary components","volume":"141","author":"Ulluwishewa","year":"2011","journal-title":"J. Nutr."},{"key":"10.1016\/j.psj.2023.103420_bib0054","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2217\/bmm.10.57","article-title":"Biomarkers of inflammation and oxidative stress in atherosclerosis","volume":"4","author":"Uno","year":"2010","journal-title":"Biomark. Med."},{"key":"10.1016\/j.psj.2023.103420_bib0055","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/s11274-020-02871-w","article-title":"A transcriptome analysis of the antibacterial mechanism of flavonoids from Sedum aizoon L. against Shewanella putrefaciens","volume":"36","author":"Wang","year":"2020","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.psj.2023.103420_bib0056","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.3748\/wjg.v10.i13.1967","article-title":"Effects of radix Puerariae flavones on liver lipid metabolism in ovariectomized rats","volume":"10","author":"Wang","year":"2004","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.psj.2023.103420_bib0057","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/jas\/skx007","article-title":"Dietary tea polyphenol supplementation improved egg production performance, albumen quality, and magnum morphology of Hy-Line Brown hens during the late laying period","volume":"96","author":"Wang","year":"2018","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0058","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1017\/S0007114510005660","article-title":"Intestinal barrier function and absorption in pigs after weaning: a review","volume":"105","author":"Wijtten","year":"2011","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.psj.2023.103420_bib0059","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1038\/s41598-021-85880-5","article-title":"Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virus","volume":"11","author":"Wu","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2023.103420_bib0060","doi-asserted-by":"crossref","first-page":"11402","DOI":"10.1021\/acs.jafc.0c04119","article-title":"Puerarin rebuilding the mucus layer and regulating mucin-utilizing bacteria to relieve ulcerative colitis","volume":"68","author":"Wu","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2023.103420_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101358","article-title":"Effects of Bacillus subtilis and Bacillus licheniformis on growth performance, immunity, short chain fatty acid production, antioxidant capacity, and cecal microflora in broilers","volume":"100","author":"Xu","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0062","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/jpn.12778","article-title":"Effects of phyto-oestrogen quercetin on productive performance, hormones, reproductive organs and apoptotic genes in laying hens","volume":"102","author":"Yang","year":"2018","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.psj.2023.103420_bib0063","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102357","article-title":"Effects of rosemary extract supplementation in feed on growth performance, meat quality, serum biochemistry, antioxidant capacity, and immune function of meat ducks","volume":"102","author":"Yao","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0064","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1142\/S0192415X2350009X","article-title":"Anti-inflammatory and anti-oxidative effects of puerarin in postmenopausal cardioprotection: roles of Akt and heme oxygenase-1","volume":"51","author":"Yen","year":"2023","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.psj.2023.103420_bib0065","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S1095-6433(03)00244-7","article-title":"Intestinal and eggshell calbindin, and bone ash of laying hens as influenced by age and molting","volume":"136","author":"Yosefi","year":"2003","journal-title":"Comp. Biochem. Physiol. Mol. Integr. Physiol."},{"key":"10.1016\/j.psj.2023.103420_bib0066","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.3382\/ps\/pew097","article-title":"Effect of tea polyphenols on production performance, egg quality, and hepatic antioxidant status of laying hens in vanadium-containing diets","volume":"95","author":"Yuan","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0067","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/j.psj.2019.11.017","article-title":"Yeast culture promotes the production of aged laying hens by improving intestinal digestive enzyme activities and the intestinal health status","volume":"99","author":"Zhang","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0068","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101115","article-title":"Dietary supplementation with daidzein and Chinese herbs, independently and combined, improves laying performance, egg quality and plasma hormone levels of post-peak laying hens","volume":"100","author":"Zhang","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2023.103420_bib0069","doi-asserted-by":"crossref","first-page":"4746","DOI":"10.1007\/s12011-021-02603-7","article-title":"Dietary selenized glucose increases selenium concentration and antioxidant capacity of the liver, oviduct, and spleen in laying hens","volume":"199","author":"Zhao","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2023.103420_bib0070","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.18632\/aging.204033","article-title":"Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling","volume":"14","author":"Zhou","year":"2022","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.psj.2023.103420_bib0071","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1002\/ptr.5083","article-title":"Puerarin: a review of pharmacological effects","volume":"28","author":"Zhou","year":"2014","journal-title":"Phytother. Res."},{"key":"10.1016\/j.psj.2023.103420_bib0072","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101387","article-title":"Effect of different concentrations of neohesperidin dihydrochalcone on performance, egg quality, serum biochemistry and intestinal morphology in laying hens","volume":"100","author":"Zhu","year":"2021","journal-title":"Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579123009409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579123009409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T19:58:27Z","timestamp":1714247907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579123009409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":72,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0032579123009409"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2023.103420","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of puerarin as a feed additive on the laying performance, egg quality, endocrine hormones, antioxidant capacity, and intestinal morphology of aged laying hens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2023.103420","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"103420"}}