{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T02:35:11Z","timestamp":1787452511605,"version":"build-2736575974"},"reference-count":53,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:00:00Z","timestamp":1710115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008011","name":"Gorgan University of Agricultural Sciences and Natural Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008011","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.psj.2024.103664","type":"journal-article","created":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T06:50:44Z","timestamp":1710571844000},"page":"103664","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Barley sprouts and D-Aspartic acid supplementation improves fertility, hatchability, and semen quality in aging male broiler breeders by up-regulating StAR and P450SCC gene expressions"],"prefix":"10.1016","volume":"103","author":[{"given":"Sarallah Yarmohammadi","family":"Barbarestani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firooz","family":"Samadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2589-1463","authenticated-orcid":false,"given":"Zarbakht Ansari","family":"Pirsaraei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4440-3584","authenticated-orcid":false,"given":"Mojtaba","family":"Zaghari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.103664_bib0001","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.anifeedsci.2019.04.011","article-title":"Evaluation of hydroponic barley sprouts as a feed supplement for laying Japanese quail: Effects on egg production, egg quality, fertility, blood constituents, and internal organs","volume":"252","author":"Abouelezz","year":"2019","journal-title":"Anim. Feed. Sci. Technol."},{"key":"10.1016\/j.psj.2024.103664_bib0002","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.anireprosci.2014.03.006","article-title":"Reproductive performance, semen quality, and fatty acid profile of spermatozoa in senescent broiler breeder roosters as enhanced by the long-term feeding of dried apple pomace","volume":"147","author":"Akhlaghi","year":"2014","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0003","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.foodchem.2009.07.032","article-title":"Polyphenol composition and in vitro antioxidant activity of amaranth, quinoa buckwheat and wheat as affected by sprouting and baking","volume":"119","author":"Alvarez-Jubete","year":"2010","journal-title":"Food. Chem."},{"key":"10.1016\/j.psj.2024.103664_bib0004","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1071\/RD17072","article-title":"D- Aspartate amends reproductive performance of aged roosters by changing gene expression and testicular histology","volume":"30","author":"Ansari","year":"2018","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.psj.2024.103664_bib0005","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.theriogenology.2017.01.014","article-title":"Improvement of post-thawed sperm quality and fertility of Arian rooster by oral administration of d-aspartic acid","volume":"92","author":"Ansari","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2024.103664_bib0006","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3382\/ps.0750755","article-title":"Age effect of male and female broiler breeders on sperm penetration of the perivitelline layer overlying the germinal disc","volume":"75","author":"Bramwell","year":"1996","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0007","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0023-6438(95)80008-5","article-title":"Use of a free radical method to evaluate antioxidant activity","volume":"28","author":"Brand-Williams","year":"1995","journal-title":"LWT \u2013 Food. Sci. Technol."},{"key":"10.1016\/j.psj.2024.103664_bib0008","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3382\/ps.0160019","article-title":"The collection of spermatozoa from the domestic fowl and turkey","volume":"16","author":"Burrows","year":"1937","journal-title":"Poult. Sci"},{"key":"10.1016\/j.psj.2024.103664_bib0009","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/473056","article-title":"Effects of a dietary supplement with barley sprout extract on blood cholesterol metabolism","volume":"2015","author":"Byun","year":"2015","journal-title":"Evid-Based. Complement. Altern. Med."},{"key":"10.1016\/j.psj.2024.103664_bib0010","doi-asserted-by":"crossref","first-page":"14864","DOI":"10.1073\/pnas.2536658100","article-title":"CatSper1 required for evoked Ca entry and control of flagellar function in sperm","volume":"100","author":"Carlson","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.psj.2024.103664_bib0011","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1093\/humupd\/dmu058","article-title":"The effects of dietary polyphenols on reproductive health and early development","volume":"21","author":"Christina","year":"2015","journal-title":"Hum. Reprod. Update."},{"key":"10.1016\/j.psj.2024.103664_bib0012","first-page":"699","article-title":"Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release","volume":"14","author":"D'Aniello","year":"2000","journal-title":"F. A. S. E. B. J."},{"key":"10.1016\/j.psj.2024.103664_bib0013","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4236\/asm.2012.24008","article-title":"D-Aspartate, a key element for the improvement of sperm quality","volume":"2","author":"D'Aniello","year":"2012","journal-title":"Adv. Sex. Med."},{"key":"10.1016\/j.psj.2024.103664_bib0014","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1007\/s00726-014-1759-2","article-title":"Current knowledge of D-aspartate in glandular tissues","volume":"46","author":"Di Fiore","year":"2014","journal-title":"Amino Acids"},{"key":"10.1016\/j.psj.2024.103664_bib0015","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.3390\/ijms17071127","article-title":"Molecular mechanisms elicited by D-aspartate in Leydig cells and spermatogonia","volume":"17","author":"Di Fiore","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0016","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/10942910903160364","article-title":"Antioxidant activity and total phenolic content in some cereals and legumes","volume":"14","author":"Djordjevic","year":"2011","journal-title":"Int. J. Food. Prop."},{"key":"10.1016\/j.psj.2024.103664_bib0017","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0076-6879(90)86134-H","article-title":"Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal","volume":"186","author":"Esterbauer","year":"1990","journal-title":"Meth. Enzymol."},{"key":"10.1016\/j.psj.2024.103664_bib0018","doi-asserted-by":"crossref","first-page":"537","DOI":"10.5352\/JLS.2016.26.5.537","article-title":"Anti-oxidant and anti-inflammatory activities of barley sprout extract","volume":"26","author":"Eun","year":"2016","journal-title":"J. Life. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0019","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cryobiol.2016.12.011","article-title":"L-carnitine is a survival factor for chilled storage of rooster semen for a long time","volume":"74","author":"Fattah","year":"2017","journal-title":"Cryobiology"},{"key":"10.1016\/j.psj.2024.103664_bib0020","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.cryobiol.2016.10.009","article-title":"L-Carnitine in rooster semen cryopreservation: flow cytometric, biochemical and motion findings for frozen-thawed sperm","volume":"74","author":"Fattah","year":"2017","journal-title":"Cryobiology"},{"key":"10.1016\/j.psj.2024.103664_bib0021","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1248\/bpb.28.1566","article-title":"Free D-aspartate in mammals","volume":"28","author":"Furuchi","year":"2005","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.psj.2024.103664_bib0022","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s40104-021-00633-8","article-title":"Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK\/Nrf2 pathway in aging layer breeder roosters","volume":"12","author":"Gao","year":"2021","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2024.103664_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2020.103594","article-title":"Germination and drying induced changes in the composition and content of phenolic compounds in naked barley","volume":"95","author":"Ge","year":"2021","journal-title":"J. Food. Compos. Anal."},{"key":"10.1016\/j.psj.2024.103664_bib0024","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1530\/rep.1.00374","article-title":"Intracellular calcium and protein tyrosine phosphorylation during the release of bovine sperm adhering to the fallopian tube epithelium in vitro","volume":"129","author":"Gualtieri","year":"2005","journal-title":"Reprod"},{"key":"10.1016\/j.psj.2024.103664_bib0025","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.anireprosci.2016.12.012","article-title":"Effects of dietary soybean isoflavones (SI) on reproduction in the young breeder rooster","volume":"177","author":"Heng","year":"2017","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0026","doi-asserted-by":"crossref","first-page":"e12816","DOI":"10.1111\/and.12816","article-title":"Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing","volume":"50","author":"Huang","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.psj.2024.103664_bib0027","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ajme.2017.09.001","article-title":"First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid","volume":"54","author":"Ighodaro","year":"2018","journal-title":"Alexandria. J. Med."},{"key":"10.1016\/j.psj.2024.103664_bib0028","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1002\/fsn3.2936","article-title":"Hordeum vulgare L. microgreen mitigates reproductive dysfunction and oxidative stress in streptozotocin-induced diabetes and aflatoxicosis in male rats","volume":"10","author":"Khattab","year":"2022","journal-title":"Food. Sci. Nutr."},{"key":"10.1016\/j.psj.2024.103664_bib0029","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real time quantitative PCR and the 2\u2212 \u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2024.103664_bib0030","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.rvsc.2008.03.010","article-title":"Efficacy of evaluation of rooster sperm morphology using different staining methods","volume":"85","author":"Lukaszewicz","year":"2008","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0031","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/j.1939-4640.1996.tb01827.x","article-title":"Are Leydig cell steroidogenic enzymes differentially regulated with aging?","volume":"17","author":"Luo","year":"1996","journal-title":"J. Androl."},{"key":"10.1016\/j.psj.2024.103664_bib0032","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/j.1939-4640.2001.tb02165.x","article-title":"Leydig cell aging: steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme","volume":"22","author":"Luo","year":"2001","journal-title":"J. Androl."},{"key":"10.1016\/j.psj.2024.103664_bib53","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.cryobiol.2010.06.009","article-title":"Antioxidant supplementation improve boar sperm charasterictics and fertility after cryopreversation: comparison between systein and rosemary","volume":"61","author":"Malo","year":"2010","journal-title":"Cryobiology"},{"key":"10.1016\/j.psj.2024.103664_bib0033","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.theriogenology.2020.10.017","article-title":"Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters","volume":"159","author":"Nanwei","year":"2021","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2024.103664_bib0034","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.steroids.2014.03.016","article-title":"Stimulation of androgen production by D-aspartate through the enhancement of StAR, P450scc and 3\u03b2-HSD mRNA levels in vivo rat testis and in culture of immature rat Leydig cells","volume":"84","author":"Raucci","year":"2014","journal-title":"Steroids"},{"key":"10.1016\/j.psj.2024.103664_bib0035","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.3382\/ps.2008-00542","article-title":"Use of the hypo-osmotic swelling test and aniline blue staining to improve the evaluation of seasonal sperm variation in native Spanish free-range poultry","volume":"88","author":"Santiago-Moreno","year":"2009","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0036","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.theriogenology.2013.12.009","article-title":"D- aspartate affects NMDA receptor-extracellular signal regulated kinase pathway and upregulates androgen receptor expression in the rat testis","volume":"81","author":"Santillo","year":"2014","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2024.103664_bib0037","series-title":"SAS\/STAT User's Guide Release 9.1","year":"2002"},{"key":"10.1016\/j.psj.2024.103664_bib0038","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1262\/jrd.2013-038","article-title":"Sperm storage in the female reproductive tract in birds","volume":"59","author":"Sasanami","year":"2013","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.psj.2024.103664_bib0039","first-page":"621","article-title":"D-Aspartate depletion perturbs steroidogenesis and spermatogenesis in mice","volume":"13","author":"Santillo","year":"2023","journal-title":"Biomol"},{"key":"10.1016\/j.psj.2024.103664_bib0040","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1021\/jf3041879","article-title":"Effect of the growth stage and cultivar on policosanol profiles of barley sprouts and their adenosine 50 monophosphate-activated protein kinase activation","volume":"61","author":"Seo","year":"2013","journal-title":"J. Agric. Food. Chem."},{"key":"10.1016\/j.psj.2024.103664_bib0041","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.theriogenology.2014.07.044","article-title":"Fertility and flow cytometric evaluations of frozen-thawed rooster semen in cryopreservation medium containing low-density lipoprotein","volume":"83","author":"Shahverdi","year":"2015","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2024.103664_bib0042","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0076-6879(99)99017-1","article-title":"Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent, oxidants and antioxidants","volume":"299","author":"Singleton","year":"1999","journal-title":"Meth. Enzymo."},{"key":"10.1016\/j.psj.2024.103664_bib0043","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.foodchem.2011.04.020","article-title":"Essential rosemary oil protects testicular cells against DNA-damaging effects of H2O2 and DMNQ","volume":"129","author":"Slamenova","year":"2011","journal-title":"Food. Chem."},{"key":"10.1016\/j.psj.2024.103664_bib0044","first-page":"63","article-title":"Total phenolic pontent, flavonoid concentration and antioxidant activity of Marrubium Peregrinum L. extracts","volume":"33","author":"Stankovi\u0107","year":"2011","journal-title":"Kragujev. J. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0045","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/j.1939-4640.1996.tb01830.x","article-title":"Lipid peroxidation and human sperm motility:protective role of vitamin E","volume":"17","author":"Suleiman","year":"1996","journal-title":"J. Androl."},{"key":"10.1016\/j.psj.2024.103664_bib0046","first-page":"243","article-title":"Relationship of sperm morphology with reproductive hormone levels in infertile men","volume":"18","author":"Tang","year":"2012","journal-title":"Natl. J. Androl."},{"key":"10.1016\/j.psj.2024.103664_bib0047","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.psj.2019.12.031","article-title":"Amelioration effects of n-3, n-6 sources of fatty acids and rosemary leaves powder on the semen parameters, reproductive hormones, and fatty acid analysis of sperm in aged Ross broiler breeder roosters","volume":"99","author":"Teymourizadeh","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.103664_bib0048","article-title":"Bioactive characteristics and storage of salt mixtures seasoned with powdered cereal sprouts","author":"Tumbas \u0160aponjac","year":"2019","journal-title":"J. Chem."},{"key":"10.1016\/j.psj.2024.103664_bib0049","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2298\/APT1647095T","article-title":"Optimization of the composition of the powdered cereal sprouts mixtures","volume":"47","author":"Tumbas \u0160aponjac","year":"2016","journal-title":"Acta. Period. Technol."},{"key":"10.1016\/j.psj.2024.103664_bib0050","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1006\/gcen.1999.7276","article-title":"Fertility decline in aging roosters is related to increased testicular and plasma levels of estradiol","volume":"115","author":"Weil","year":"1999","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.psj.2024.103664_bib0051","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.rbmo.2014.02.004","article-title":"Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility","volume":"28","author":"Wright","year":"2014","journal-title":"Reprod. Biomed. Online."},{"key":"10.1016\/j.psj.2024.103664_bib0052","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.theriogenology.2023.10.030","article-title":"Dietary supplementation with barley sprouts and D-Aspartic acid improves reproductive hormone concentrations, testicular histology, antioxidant status, and mRNA expressions of apoptosis-related genes in aged male broiler breeder roosters","volume":"214","author":"Yarmohammadi Barbarestani","year":"2023","journal-title":"Theriogenology"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124002438?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124002438?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T17:40:05Z","timestamp":1727286005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124002438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S0032579124002438"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.103664","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Barley sprouts and D-Aspartic acid supplementation improves fertility, hatchability, and semen quality in aging male broiler breeders by up-regulating StAR and P450SCC gene expressions","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.103664","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"103664"}}