{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:09:05Z","timestamp":1790982545670,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.psj.2024.104052","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T06:16:30Z","timestamp":1719900990000},"page":"104052","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["MAPK signaling pathway participates in the regulation of intestinal phosphorus and calcium absorption in broiler chickens via 1,25-dihydroxyvitamin D3"],"prefix":"10.1016","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4213-9847","authenticated-orcid":false,"given":"Jincheng","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianliang","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxia","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3639-1907","authenticated-orcid":false,"given":"Li","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingbing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanxin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangli","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.104052_bib0001","unstructured":"Association of Official Analytical Chemists (AOAC). 2005. Official method of analysis, international 18th edition, AOAC, Gaithersburg, MD, USA, accessed May 8, 2020."},{"key":"10.1016\/j.psj.2024.104052_bib0002","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s00424-002-0969-8","article-title":"Involvement of the MAPK-kinase pathway in the PTH-mediated regulation of the proximal tubule type IIa Na+\/Pi cotransporter in mouse kidney","volume":"446","author":"Bacic","year":"2003","journal-title":"Pflug. Arch. - Eur. J. Phy."},{"key":"10.1016\/j.psj.2024.104052_bib0004","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/japr\/12.1.45","article-title":"Effect of source and level of vitamin D on live performance and bone development in growing broilers","volume":"12","author":"Fritts","year":"2003","journal-title":"J. Appl. Poult. Res."},{"key":"10.1016\/j.psj.2024.104052_bib0005","doi-asserted-by":"crossref","first-page":"6005","DOI":"10.3382\/ps\/pez407","article-title":"Candidate genes of the transcellular and paracellular calcium absorption pathways in the small intestine of laying hens","volume":"98","author":"Gloux","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0006","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.3382\/ps\/pex407","article-title":"Age, phosphorus, and 25-hydroxycholecalciferol regulate mRNA expression of vitamin D receptor and sodium-phosphate cotransporter in the small intestine of broiler chickens","volume":"97","author":"Han","year":"2018","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0007","first-page":"336","article-title":"Intestinal segment and vitamin D3 concentration affect gene expression levels of calcium and phosphorus transporters in broiler chickens","volume":"65","author":"Han","year":"2023","journal-title":"J. Anim. Sci. Technol."},{"key":"10.1016\/j.psj.2024.104052_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101488","article-title":"Low-calcium diets increase duodenal mRNA expression of calcium and phosphorus transporters and claudins but compromise growth performance irrespective of microbial phytase inclusion in broilers","volume":"100","author":"Hu","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0009","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/ndt\/gfaa156","article-title":"Evidence of an intestinal phosphate transporter alternative to type IIb sodium-dependent phosphate transporter in rats with chronic kidney disease","volume":"36","author":"Ichida","year":"2021","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.psj.2024.104052_bib0010","doi-asserted-by":"crossref","first-page":"138","DOI":"10.22358\/jafs\/157475\/2023","article-title":"25-hydroxycholecalciferol affects growth performance, bone calcium content and intestinal calcium transporter gene expression in broiler chickens","volume":"32","author":"Liu","year":"2023","journal-title":"J. Anim. Feed Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0011","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394Ct method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2024.104052_bib0012","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.5713\/ab.22.0058","article-title":"Age quadratically affects intestinal calcium and phosphorus transporter gene expression in broiler chickens","volume":"35","author":"Lv","year":"2022","journal-title":"Anim. Biosci."},{"key":"10.1016\/j.psj.2024.104052_bib0013","doi-asserted-by":"crossref","first-page":"7392","DOI":"10.1073\/pnas.0402207101","article-title":"Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells","volume":"101","author":"Nemere","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.psj.2024.104052_bib0014","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.biocel.2003.08.005","article-title":"Tyrosine phosphorylation signalling dependent on 1\u03b1,25(OH)2-vitamin D3 in rat intestinal cells: effect of ageing","volume":"36","author":"Pardo","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.psj.2024.104052_bib0015","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.biocel.2005.12.018","article-title":"1\u03b1,25(OH)2-Vitamin D3 stimulates intestinal cell p38 MAPK activity and increases c-Fos expression","volume":"38","author":"Pardo","year":"2006","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.psj.2024.104052_bib0016","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.3382\/ps\/pey546","article-title":"Effect of early neonatal development and delayed feeding post-hatch on jejunal and ileal calcium and phosphorus transporter genes expression in broiler chickens","volume":"98","author":"Proszkowiec-Weglarz","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0017","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3382\/ps.0750090","article-title":"Effect of dietary 1,25-dihydroxycholecalciferol level on broiler performance","volume":"75","author":"Roberson","year":"1996","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0018","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00424-022-02691-x","article-title":"Phosphate intake, hyperphosphatemia, and kidney function","volume":"474","author":"Rubio-Aliaga","year":"2022","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.psj.2024.104052_bib0019","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/ps\/83.1.61","article-title":"Effect of microbial phytase on ileal digestibility of phytate phosphorus, total phosphorus, and amino acids in a low-phosphorus diet for broilers","volume":"83","author":"Rutherfurd","year":"2004","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0020","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1681\/ASN.2009050559","article-title":"Intestinal Npt2b plays a major role in phosphate absorption and homeostasis","volume":"20","author":"Sabbagh","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.psj.2024.104052_bib0021","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.3382\/ps.0741919","article-title":"25-hydroxycholecalciferol in poultry nutrition","volume":"74","author":"Soares","year":"1995","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104052_bib0022","unstructured":"Statistical Analysis Systems Institute. 2002. SAS User\u2019s Guide: Statistics, version 9.0. SAS Institute Inc., Cary, NC, USA, accessed July 15, 2020."},{"key":"10.1016\/j.psj.2024.104052_bib0023","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3109\/10799893.2015.1030412","article-title":"Signaling pathway of MAPK\/ERK in cell proliferation, differentiation, migration, senescence and apoptosis","volume":"35","author":"Sun","year":"2015","journal-title":"J. Recept. Signal. Transduct. Res."},{"key":"10.1016\/j.psj.2024.104052_bib0024","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.taap.2008.05.026","article-title":"Role of rat sodium\/phosphate cotransporters in the cell membrane transport of arsenate","volume":"232","author":"Villa-Bellosta","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.psj.2024.104052_bib0025","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1002\/cphy.c200014","article-title":"Intestinal calcium absorption","volume":"11","author":"Wongdee","year":"2021","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.psj.2024.104052_bib0026","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1152\/ajpcell.00412.2001","article-title":"Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)2 vitamin D3","volume":"282","author":"Xu","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.psj.2024.104052_bib0027","first-page":"5202","article-title":"Differentially expressed genes in vitamin D regulating calcium and phosphorus absorption in the duodenum of broiler chickens using RNA-sequencing","volume":"31","author":"Yang","year":"2019","journal-title":"Chinese J. Anim. Nutr."},{"key":"10.1016\/j.psj.2024.104052_bib0028","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1210\/endo.139.4.5903","article-title":"Distinct, tissue-specific regulation of vitamin D receptor in the intestine, kidney, and skin by dietary calcium and vitamin D","volume":"139","author":"Zineb","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2024.104052_bib0029","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/exd.14147","article-title":"Vitamin D receptors: In the nucleus but also at membranes?","volume":"29","author":"Zmijewski","year":"2020","journal-title":"Exp. Dermatol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912400631X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912400631X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T11:34:28Z","timestamp":1734694468000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003257912400631X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S003257912400631X"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104052","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MAPK signaling pathway participates in the regulation of intestinal phosphorus and calcium absorption in broiler chickens via 1,25-dihydroxyvitamin D3","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104052"}}