{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:44:01Z","timestamp":1791416641833,"version":"4.3.3"},"reference-count":50,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007062","name":"Yangzhou University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.psj.2024.104152","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T23:26:38Z","timestamp":1722900398000},"page":"104152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Co-exposure of polyvinyl chloride microplastics with cadmium promotes nonalcoholic fatty liver disease in female ducks through oxidative stress and glycolipid accumulation"],"prefix":"10.1016","volume":"103","author":[{"given":"Yan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengqi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waseem","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinglong","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianchun","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2637-3895","authenticated-orcid":false,"given":"Hui","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.104152_bib0001","doi-asserted-by":"crossref","first-page":"138969","DOI":"10.1016\/j.chemosphere.2023.138969","article-title":"Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish","volume":"334","author":"Al Marshoudi","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib0002","doi-asserted-by":"crossref","first-page":"13495","DOI":"10.3390\/ijerph192013495","article-title":"Are ingested or inhaled microplastics involved in nonalcoholic fatty liver disease?","volume":"19","author":"Auguet","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.psj.2024.104152_bib0003","doi-asserted-by":"crossref","first-page":"142518","DOI":"10.1016\/j.scitotenv.2020.142518","article-title":"Micro- and nanoplastic induced cellular toxicity in mammals: A review","volume":"755","author":"Banerjee","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0004","article-title":"Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: A mechanistic study","volume":"244","author":"Bharati","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.psj.2024.104152_bib0005","doi-asserted-by":"crossref","first-page":"147620","DOI":"10.1016\/j.scitotenv.2021.147620","article-title":"A critical review on the interactions of microplastics with heavy metals: Mechanism and their combined effect on organisms and humans","volume":"788","author":"Cao","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0006","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1126\/science.aar7734","article-title":"Microplastics research-from sink to source","volume":"360","author":"Chelsea","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.psj.2024.104152_bib0007","doi-asserted-by":"crossref","first-page":"122589","DOI":"10.1016\/j.envpol.2023.122589","article-title":"Microplastics evidence in yolk and liver of loggerhead sea turtles (Caretta caretta), a pilot study","volume":"337","author":"Chemello","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.psj.2024.104152_bib0008","doi-asserted-by":"crossref","first-page":"152514","DOI":"10.1016\/j.scitotenv.2021.152514","article-title":"Combined effects of polystyrene microplastics and cadmium on oxidative stress, apoptosis, and GH\/IGF axis in zebrafish early life stages","volume":"813","author":"Chen","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0009","doi-asserted-by":"crossref","first-page":"150328","DOI":"10.1016\/j.scitotenv.2021.150328","article-title":"Polystyrene microplastics induce hepatotoxicity and disrupt lipid metabolism in the liver organoids","volume":"806","author":"Cheng","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0010","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.envpol.2017.07.089","article-title":"Microplastics in livers of European anchovies (Engraulis encrasicolus, L.)","volume":"229","author":"Collard","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.psj.2024.104152_bib0011","first-page":"1","article-title":"Polyethylene microplastic toxicity to the terrestrial snail Cantareus aspersus: Size matters","volume":"29","author":"Colpaert","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.psj.2024.104152_bib52","series-title":"Nutrient Requirements of Poultry","year":"1994"},{"key":"10.1016\/j.psj.2024.104152_bib0012","doi-asserted-by":"crossref","first-page":"115417","DOI":"10.1016\/j.ecoenv.2023.115417","article-title":"Oral exposure to polyethylene microplastics induces inflammatory and metabolic changes and promotes fibrosis in mouse liver","volume":"264","author":"Djouina","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.psj.2024.104152_bib0013","doi-asserted-by":"crossref","DOI":"10.1093\/ndt\/gfad063a_6111","article-title":"#6111 First Identification And Characterization of Microplastics in Human Kidney and Urine","volume":"38","author":"Exacoustos","year":"2023","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.psj.2024.104152_bib0014","doi-asserted-by":"crossref","first-page":"4298","DOI":"10.1039\/D2BM02116A","article-title":"Microplastic-contaminated antibiotics as an emerging threat to mammalian liver: Enhanced oxidative and inflammatory damages","volume":"11","author":"Fu","year":"2023","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.psj.2024.104152_bib0015","doi-asserted-by":"crossref","first-page":"5631","DOI":"10.3390\/ijerph19095631","article-title":"Chronic microplastic exposure and cadmium accumulation in blue crabs","volume":"19","author":"Hern\u00e1ndez-L\u00f3pez","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.psj.2024.104152_bib0016","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s11605-013-2210-9","article-title":"Cadmium exposure and liver disease among US adults","volume":"17","author":"Hyder","year":"2013","journal-title":"J. Gastrointest. Surg."},{"key":"10.1016\/j.psj.2024.104152_bib0017","doi-asserted-by":"crossref","first-page":"133990","DOI":"10.1016\/j.chemosphere.2022.133990","article-title":"Toxicity evaluation of polypropylene microplastic on marine microcrustacean Artemia salina: An analysis of implications and vulnerability","volume":"296","author":"Jeyavani","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib49","article-title":"Rapid detection of sulfamethazine and ofloxacin residues in duck meat using synchronous fluorescence spectroscopy coupled with chemometric methods","volume":"100","author":"Jian","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104152_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2017.11.103","article-title":"Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans","volume":"619-620","author":"Lei","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0019","doi-asserted-by":"crossref","first-page":"127754","DOI":"10.1016\/j.jhazmat.2021.127754","article-title":"Microplastics increase the accumulation of phenanthrene in the ovaries of marine medaka (Oryzias melastigma) and its transgenerational toxicity","volume":"424","author":"Li","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.psj.2024.104152_bib0020","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1016\/j.scitotenv.2011.04.038","article-title":"Environmental and health hazard ranking and assessment of plastic polymers based on chemical composition","volume":"409","author":"Lithner","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.166074","article-title":"Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium","volume":"902","author":"Liu","year":"2023","journal-title":"Sci. Total Environm."},{"key":"10.1016\/j.psj.2024.104152_bib0022","doi-asserted-by":"crossref","first-page":"107038","DOI":"10.1016\/j.envint.2021.107038","article-title":"Glyphosate damages blood-testis barrier via NOX1-triggered oxidative stress in rats: Long-term exposure as a potential risk for male reproductive health","volume":"159","author":"Liu","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.psj.2024.104152_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131918","article-title":"Impacts of polypropylene microplastics on lipid profiles of mouse liver uncovered by lipidomics analysis and Raman spectroscopy","volume":"458","author":"Liu","year":"2023","journal-title":"J. Hazard. Mat."},{"key":"10.1016\/j.psj.2024.104152_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.136153","article-title":"An overview of microplastics in oysters: Analysis, hazards, and depuration","volume":"422","author":"Liu","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.psj.2024.104152_bib0025","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.chemosphere.2018.03.145","article-title":"Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio)","volume":"202","author":"Lu","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib0026","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1021\/acs.est.6b00183","article-title":"Uptake and Accumulation of polystyrene microplastics in zebrafish (Danio rerio) and toxic effects in liver","volume":"50","author":"Lu","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.psj.2024.104152_bib0027","doi-asserted-by":"crossref","first-page":"160155","DOI":"10.1016\/j.scitotenv.2022.160155","article-title":"Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin","volume":"860","author":"Missawi","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0028","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.exger.2018.06.010","article-title":"The influence of ageing on the extrapineal melatonin synthetic pathway","volume":"110","author":"Popovi\u0107","year":"2018","journal-title":"Exp. Geront."},{"key":"10.1016\/j.psj.2024.104152_bib0029","doi-asserted-by":"crossref","first-page":"134455","DOI":"10.1016\/j.scitotenv.2019.134455","article-title":"Environmental exposure to microplastics: An overview on possible human health effects","volume":"702","author":"Prata","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0030","first-page":"5991","article-title":"Reactive oxygen species control osteoblast apoptosis through SIRT1\/PGC-1\u03b1\/P53Lys382 signaling, mediating the onset of Cd-induced osteoporosis","volume":"71","author":"Ran","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2024.104152_bib0031","article-title":"Serum cadmium is associated with hepatic steatosis and fibrosis: Korean national health and nutrition examination survey data IV-VII","volume":"101","author":"Seogoo","year":"2022","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.psj.2024.104152_bib0032","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1007\/s12011-023-03835-5","article-title":"Liver injury induced by exposure to polystyrene microplastics alone or in combination with cadmium in mice is mediated by oxidative stress and apoptosis","volume":"202","author":"Sheng","year":"2024","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2024.104152_bib0033","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.fsi.2019.12.042","article-title":"Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles","volume":"97","author":"Shi","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.psj.2024.104152_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140372","article-title":"Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels-ATP-P2\u00d77 pathway","volume":"344","author":"Sun","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140372","article-title":"Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2\u00d77 pathway","volume":"344","author":"Sun","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib0036","doi-asserted-by":"crossref","first-page":"133151","DOI":"10.1016\/j.jhazmat.2023.133151","article-title":"TFAM-mediated intercellular lipid droplet transfer promotes cadmium-induced mice nonalcoholic fatty liver disease","volume":"465","author":"Sun","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.psj.2024.104152_bib0037","article-title":"Microplastics detected in cirrhotic liver tissue","volume":"82","author":"Thomas","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.psj.2024.104152_bib0038","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1017\/S1431927619015071","article-title":"In vivo multivesicular body and exosome secretion in the intestinal epithelial cells of turtles during hibernation","volume":"25","author":"Vistro","year":"2019","journal-title":"Microsc. Microanal."},{"key":"10.1016\/j.psj.2024.104152_bib0039","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12302-014-0012-7","article-title":"Microplastics in freshwater ecosystems: What we know and what we need to know","volume":"26","author":"Wagner","year":"2014","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.psj.2024.104152_bib0040","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.chemosphere.2019.06.196","article-title":"Adsorption characteristics of cadmium onto microplastics from aqueous solutions","volume":"235","author":"Wang","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2024.104152_bib0041","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.1007\/s12011-021-02917-6","article-title":"Single and Combined effects of microplastics and cadmium on the cadmium accumulation and biochemical and immunity of Channa argus","volume":"200","author":"Wang","year":"2022","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2024.104152_bib0042","doi-asserted-by":"crossref","first-page":"171230","DOI":"10.1016\/j.scitotenv.2024.171230","article-title":"Micro(nano)-plastics exposure induced programmed cell death and corresponding influence factors","volume":"921","author":"Wu","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0043","doi-asserted-by":"crossref","first-page":"134699","DOI":"10.1016\/j.scitotenv.2019.134699","article-title":"Microplastics in aquatic environments: Occurrence, accumulation, and biological effects","volume":"703","author":"Xu","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.psj.2024.104152_bib0044","doi-asserted-by":"crossref","first-page":"114105","DOI":"10.1016\/j.ecoenv.2022.114105","article-title":"Gender difference in hepatic AMPK pathway activated lipid metabolism induced by aged polystyrene microplastics exposure","volume":"245","author":"Yang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.psj.2024.104152_bib0045","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1038\/s41467-023-37142-3","article-title":"Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K\/AKT\/PDGF axis activation in male mice","volume":"14","author":"Ye","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2024.104152_bib0046","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jare.2022.10.015","article-title":"Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis","volume":"52","author":"Yin","year":"2023","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.psj.2024.104152_bib0047","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/ajim.23540","article-title":"Worker studies suggest unique liver carcinogenicity potential of polyvinyl chloride microplastics","volume":"66","author":"Zarus","year":"2023","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.psj.2024.104152_bib0048","doi-asserted-by":"crossref","first-page":"162713","DOI":"10.1016\/j.scitotenv.2023.162713","article-title":"Detection and characterization of microplastics in the human testis and semen","volume":"877","author":"Zhao","year":"2023","journal-title":"Sci. Total Environ."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124007314?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124007314?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T15:44:45Z","timestamp":1727365485000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124007314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S0032579124007314"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104152","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Co-exposure of polyvinyl chloride microplastics with cadmium promotes nonalcoholic fatty liver disease in female ducks through oxidative stress and glycolipid accumulation","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104152","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104152"}}