{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:08:05Z","timestamp":1777633685728,"version":"3.51.4"},"reference-count":66,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31902174"],"award-info":[{"award-number":["31902174"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD1300300"],"award-info":[{"award-number":["2023YFD1300300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.psj.2024.104444","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T05:59:22Z","timestamp":1730181562000},"page":"104444","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Threonine modulates the STAT3-SCD1 pathway to reduce fatty acid metabolism in duck hepatocytes"],"prefix":"10.1016","volume":"103","author":[{"given":"Zhong","family":"Zhuang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenqian","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongpeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijia","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minghong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulin","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixiu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shihao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guobin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.psj.2024.104444_bib0001","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.biopha.2009.04.047","article-title":"Glycine regulates inflammatory markers modifying the energetic balance through PPAR and UCP-2","volume":"64","author":"Almanza-Perez","year":"2010","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0002","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13046-021-02067-6","article-title":"SCD1, autophagy and cancer: implications for therapy","volume":"40","author":"Ascenzi","year":"2021","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.psj.2024.104444_bib0003","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1017\/S1751731113000050","article-title":"Effect of dietary amounts of inorganic and organic zinc on productive and physiological traits of White Pekin ducks","volume":"7","author":"Attia","year":"2013","journal-title":"Animal"},{"issue":"11","key":"10.1016\/j.psj.2024.104444_bib0004","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.3390\/ani13111820","article-title":"Developmental changes of duckling liver and isolation of primary hepatocytes","volume":"13","author":"Bao","year":"2023","journal-title":"Animals (Basel)"},{"issue":"6 Suppl","key":"10.1016\/j.psj.2024.104444_bib0005","doi-asserted-by":"crossref","first-page":"1636S","DOI":"10.1093\/jn\/136.6.1636S","article-title":"The sulfur-containing amino acids: an overview","volume":"136","author":"Brosnan","year":"2006","journal-title":"J. Nutr."},{"issue":"4","key":"10.1016\/j.psj.2024.104444_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101708","article-title":"Protective effects of AdipoRon on the liver of Huoyan goose fed a high-fat diet","volume":"101","author":"Cao","year":"2022","journal-title":"Poult. Sci."},{"issue":"14","key":"10.1016\/j.psj.2024.104444_bib0007","doi-asserted-by":"crossref","first-page":"7772","DOI":"10.1039\/D2FO01201D","article-title":"Threonine supplementation prevents the development of fat deposition in mice fed a high-fat diet","volume":"13","author":"Chen","year":"2022","journal-title":"Food Funct"},{"issue":"4","key":"10.1016\/j.psj.2024.104444_bib0008","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/j.tjnut.2023.12.047","article-title":"Aromatic amino acids promote lipid metabolism disorders by increasing hepatic bile acid synthesis","volume":"154","author":"Chen","year":"2024","journal-title":"J. Nutr."},{"issue":"25","key":"10.1016\/j.psj.2024.104444_bib0009","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1016\/0024-3205(84)90280-7","article-title":"Differences in properties between aromatic amino acid: aromatic keto acid aminotransferases and aromatic amino acid: alpha-ketoglutarate aminotransferases","volume":"34","author":"Chia","year":"1984","journal-title":"Life Sci"},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0010","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20221316","article-title":"Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition","volume":"220","author":"Chu","year":"2022","journal-title":"J. Exp. Med."},{"issue":"2","key":"10.1016\/j.psj.2024.104444_bib0011","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1080\/00071660410001715894","article-title":"Effects of dietary threonine and crude protein on growth performance, carcase and meat composition of broiler chickens","volume":"45","author":"\u00c7iftci","year":"2004","journal-title":"Br. Poult. Sci."},{"issue":"9","key":"10.1016\/j.psj.2024.104444_bib0012","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1093\/jn\/124.9.1667","article-title":"Dietary threonine imbalance alters threonine dehydrogenase activity in isolated hepatic mitochondria of chicks and rats","volume":"124","author":"Davis","year":"1994","journal-title":"J. Nutr."},{"issue":"11","key":"10.1016\/j.psj.2024.104444_bib0013","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1093\/jn\/112.11.2177","article-title":"Threonine metabolism of chicks fed threonine-imbalanced diets","volume":"112","author":"Davis","year":"1982","journal-title":"J. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0014","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1186\/s12864-018-4520-5","article-title":"Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis","volume":"19","author":"Desert","year":"2018","journal-title":"BMC Genomics"},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0015","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/japr\/10.1.53","article-title":"Comparisons of male and female broiler responses to dietary threonine from 42 to 56 days of age","volume":"10","author":"Dozier","year":"2001","journal-title":"J. Appl. Poult. Res."},{"issue":"11","key":"10.1016\/j.psj.2024.104444_bib0016","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.biochi.2004.09.018","article-title":"SREBP transcription factors: master regulators of lipid homeostasis","volume":"86","author":"Eberl\u00e9","year":"2004","journal-title":"Biochimie"},{"issue":"1\u20132","key":"10.1016\/j.psj.2024.104444_bib0017","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11010-013-1694-7","article-title":"Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells","volume":"381","author":"Fang","year":"2013","journal-title":"Mol. Cell. Biochem."},{"issue":"12","key":"10.1016\/j.psj.2024.104444_bib0018","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1007\/s00253-022-12028-4","article-title":"Aromatic L-amino acid decarboxylases: mechanistic features and microbial applications","volume":"106","author":"Han","year":"2022","journal-title":"Appl. Microbiol Biotechnol."},{"issue":"5","key":"10.1016\/j.psj.2024.104444_bib0019","doi-asserted-by":"crossref","first-page":"805S","DOI":"10.1093\/jn\/127.5.805S","article-title":"Lipoprotein Metabolism and Fattening in Poultry","volume":"127","author":"Hermier","year":"1997","journal-title":"J. Nutr."},{"key":"10.1016\/j.psj.2024.104444_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cytogfr.2016.05.001","article-title":"STAT3 signaling in immunity","volume":"31","author":"Hillmer","year":"2016","journal-title":"Cytokine Growth Factor Rev"},{"issue":"12","key":"10.1016\/j.psj.2024.104444_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104268","article-title":"Mechanism of fatty acid transposase (CD36) promoting fat accumulation in mule ducks","volume":"103","author":"Hu","year":"2024","journal-title":"Poult. Sci."},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0022","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.plipres.2006.01.004","article-title":"Fatty acid elongases in mammals: Their regulation and roles in metabolism","volume":"45","author":"Jakobsson","year":"2006","journal-title":"Prog. Lipid Res."},{"issue":"12","key":"10.1016\/j.psj.2024.104444_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103168","article-title":"Research note: transcriptome analysis reveals differentially expressed genes regulated muscle development in Pekin ducks during dietary threonine deficiency","volume":"102","author":"Jia","year":"2023","journal-title":"Poult. Sci."},{"issue":"6","key":"10.1016\/j.psj.2024.104444_bib0024","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1080\/00071668.2017.1363871","article-title":"Threonine supplementation reduces dietary protein and improves lipid metabolism in Pekin ducks","volume":"58","author":"Jiang","year":"2017","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.psj.2024.104444_bib0025","doi-asserted-by":"crossref","first-page":"710","DOI":"10.3389\/fgene.2019.00710","article-title":"Transcriptome analysis reveals differential expression of genes regulating hepatic triglyceride metabolism in pekin ducks during dietary threonine deficiency","volume":"10","author":"Jiang","year":"2019","journal-title":"Front. Genet."},{"issue":"9","key":"10.1016\/j.psj.2024.104444_bib0026","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1016\/j.jia.2022.07.011","article-title":"Dietary threonine deficiency affects expression of genes involved in lipid metabolism in adipose tissues of Pekin ducks in a genotype-dependent manner","volume":"21","author":"Jiang","year":"2022","journal-title":"J. Integr. Agric."},{"key":"10.1016\/j.psj.2024.104444_bib0027","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.aninu.2023.01.008","article-title":"Proteomic and phosphoproteomic analysis reveal threonine deficiency increases hepatic lipid deposition in Pekin ducks via reducing STAT phosphorylation","volume":"13","author":"Jiang","year":"2023","journal-title":"Anim. Nutr."},{"issue":"5","key":"10.1016\/j.psj.2024.104444_bib0028","doi-asserted-by":"crossref","first-page":"706","DOI":"10.3390\/biom12050706","article-title":"Key Molecules of Fatty Acid Metabolism in Gastric Cancer","volume":"12","author":"Li","year":"2022","journal-title":"Biomolecules"},{"issue":"10","key":"10.1016\/j.psj.2024.104444_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2021.119080","article-title":"Peripheral IL-6\/STAT3 signaling promotes beiging of white fat","volume":"1868","author":"Li","year":"2021","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"issue":"2","key":"10.1016\/j.psj.2024.104444_bib0030","doi-asserted-by":"crossref","first-page":"976","DOI":"10.7150\/thno.63751","article-title":"Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation","volume":"12","author":"Li","year":"2022","journal-title":"Theranostics"},{"key":"10.1016\/j.psj.2024.104444_bib0031","article-title":"Comparative transcriptomic analysis of gill reveals genes belonging to mTORC1 signaling pathway associated with the resistance trait of shrimp to VPAHPND","volume":"14","author":"Liu","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0032","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1038\/s41467-024-48471-2","article-title":"Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling","volume":"15","author":"Lu","year":"2024","journal-title":"Nat. Commun."},{"issue":"17","key":"10.1016\/j.psj.2024.104444_bib0033","doi-asserted-by":"crossref","first-page":"4876","DOI":"10.1021\/acs.jafc.0c01023","article-title":"Threonine, but not lysine and methionine, reduces fat accumulation by regulating lipid metabolism in obese mice","volume":"68","author":"Ma","year":"2020","journal-title":"J. Agric. Food Chem."},{"issue":"7","key":"10.1016\/j.psj.2024.104444_bib0034","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1134\/S0006297918070039","article-title":"Why threonine is an essential amino acid in mammals and birds: studies at the enzyme level","volume":"83","author":"Malinovsky","year":"2018","journal-title":"Biochemistry (Moscow)"},{"issue":"1\u20132","key":"10.1016\/j.psj.2024.104444_bib0035","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.mce.2010.01.027","article-title":"Key role of the ERK1\/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin","volume":"319","author":"Mauvoisin","year":"2010","journal-title":"Mol. Cell Endocrinol."},{"issue":"10","key":"10.1016\/j.psj.2024.104444_bib0036","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1007\/s00216-020-02424-y","article-title":"Rapid and miniaturized qualitative and quantitative gas chromatography profiling of human blood total fatty acids","volume":"412","author":"Micalizzi","year":"2020","journal-title":"Anal. Bioanal. Chem."},{"issue":"6","key":"10.1016\/j.psj.2024.104444_bib0037","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.cmet.2007.10.014","article-title":"Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis","volume":"6","author":"Miyazaki","year":"2007","journal-title":"Cell Metab"},{"key":"10.1016\/j.psj.2024.104444_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2024.101916","article-title":"Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes","volume":"83","author":"Mori","year":"2024","journal-title":"Mol. Metab."},{"key":"10.1016\/j.psj.2024.104444_bib0039","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.plipres.2013.12.001","article-title":"Regulation of energy metabolism by long-chain fatty acids","volume":"53","author":"Nakamura","year":"2014","journal-title":"Prog. Lipid. Res."},{"issue":"10","key":"10.1016\/j.psj.2024.104444_bib0040","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.3390\/nu11102283","article-title":"Role of oleic acid in the gut-liver axis: from diet to the regulation of its synthesis via stearoyl-CoA desaturase 1 (SCD1)","volume":"11","author":"Piccinin","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.psj.2024.104444_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2007\/26839","article-title":"Comprehensive analysis of PPAR\u03b1-dependent regulation of hepatic lipid metabolism by expression profiling","author":"Rakhshandehroo","year":"2007","journal-title":"PPAR Res."},{"issue":"7","key":"10.1016\/j.psj.2024.104444_bib0042","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/s42255-020-0217-6","article-title":"Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3","volume":"2","author":"Reilly","year":"2020","journal-title":"Nat. Metab."},{"issue":"9","key":"10.1016\/j.psj.2024.104444_bib0043","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.2337\/db20-1222","article-title":"STAT3 regulates mitochondrial gene expression in pancreatic beta-cells and its deficiency induces glucose intolerance in obesity","volume":"70","author":"Schaschkow","year":"2021","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.psj.2024.104444_bib0044","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20220686","article-title":"STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection","volume":"220","author":"Sun","year":"2023","journal-title":"J Exp Med"},{"issue":"10","key":"10.1016\/j.psj.2024.104444_bib0045","doi-asserted-by":"crossref","first-page":"e4922","DOI":"10.1002\/bmc.4922","article-title":"Identifying potential serum biomarkers of breast cancer through targeted free fatty acid profiles screening based on a GC-MS platform","volume":"34","author":"Tan","year":"2020","journal-title":"Biomed. Chromatogr."},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0046","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.biochem.77.061307.091829","article-title":"Fat and beyond: the diverse biology of PPAR\u03b3","volume":"77","author":"Tontonoz","year":"2008","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.psj.2024.104444_bib0047","doi-asserted-by":"crossref","first-page":"21268","DOI":"10.18632\/oncotarget.25066","article-title":"STAT3-activated CD36 facilitates fatty acid uptake in chronic lymphocytic leukemia cells","volume":"9","author":"Uri Rozovski","year":"2018","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0048","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.cmet.2017.11.001","article-title":"JAK\/STAT3-regulated fatty acid \u03b2-oxidation is critical for breast cancer stem cell self-renewal and chemoresistance","volume":"27","author":"Wang","year":"2018","journal-title":"Cell Metab"},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0049","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1080\/21655979.2021.1924544","article-title":"Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin","volume":"12","author":"Wang","year":"2021","journal-title":"Bioengineered"},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0050","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1631\/jzus.B1300123","article-title":"Anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidea and var. angustifolia on 3T3-L1 adipocytes","volume":"15","author":"Woon","year":"2014","journal-title":"J. Zhejiang Univ. Sci. B."},{"key":"10.1016\/j.psj.2024.104444_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102461","article-title":"HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3","volume":"56","author":"Wu","year":"2022","journal-title":"Redox Biol"},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0052","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s40104-022-00709-z","article-title":"Dietary methionine deficiency stunts growth and increases fat deposition via suppression of fatty acids transportation and hepatic catabolism in Pekin ducks","volume":"13","author":"Wu","year":"2022","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"9","key":"10.1016\/j.psj.2024.104444_bib0053","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1007\/s00726-016-2254-8","article-title":"The glutamine-alpha-ketoglutarate (AKG) metabolism and its nutritional implications","volume":"48","author":"Xiao","year":"2016","journal-title":"Amino. Acids."},{"issue":"6","key":"10.1016\/j.psj.2024.104444_bib0054","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.3382\/ps\/pex443","article-title":"Effects of vitamin E on growth performance, tissue \u03b1-tocopherol, and lipid peroxidation of starter White Pekin ducks","volume":"97","author":"Xie","year":"2018","journal-title":"Poult. Sci."},{"issue":"5","key":"10.1016\/j.psj.2024.104444_bib0055","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.3382\/ps\/pew349","article-title":"Effects of low-protein diets on growth performance and carcass yield of growing White Pekin ducks","volume":"96","author":"Xie","year":"2017","journal-title":"Poult. Sci."},{"issue":"7","key":"10.1016\/j.psj.2024.104444_bib0056","doi-asserted-by":"crossref","first-page":"3534","DOI":"10.7150\/thno.70194","article-title":"SCD1\/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells","volume":"12","author":"Xuan","year":"2022","journal-title":"Theranostics"},{"issue":"44","key":"10.1016\/j.psj.2024.104444_bib0057","doi-asserted-by":"crossref","first-page":"27412","DOI":"10.1073\/pnas.2002997117","article-title":"Blocking PPARgamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression","volume":"117","author":"Yang","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"issue":"9","key":"10.1016\/j.psj.2024.104444_bib0058","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1007\/s00011-023-01776-2","article-title":"Pirfenidone ameliorates liver steatosis by targeting the STAT3-SCD1 axis","volume":"72","author":"Yang","year":"2023","journal-title":"Inflamm. Res."},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0059","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/jcp.25469","article-title":"SCD1 alters long-chain fatty acid (LCFA) composition and its expression is directly regulated by SREBP-1 and PPARgamma 1 in dairy goat mammary cells","volume":"232","author":"Yao","year":"2017","journal-title":"J. Cell Physiol."},{"issue":"5","key":"10.1016\/j.psj.2024.104444_bib0060","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1080\/15548627.2015.1017192","article-title":"The role of STAT3 in autophagy","volume":"11","author":"You","year":"2015","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0061","doi-asserted-by":"crossref","first-page":"10","DOI":"10.31083\/j.fbl2801010","article-title":"Cellular uptake, metabolism and sensing of long-chain fatty acids","volume":"28","author":"Yu","year":"2023","journal-title":"Front. Biosci. (Landmark Ed)"},{"issue":"2","key":"10.1016\/j.psj.2024.104444_bib0062","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3390\/ani9020063","article-title":"Avian liver: the forgotten organ","volume":"9","author":"Zaefarian","year":"2019","journal-title":"Animals"},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0063","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s11250-019-02086-8","article-title":"Effect of threonine and potassium carbonate on broiler chicken performance, immunity, carcass traits, and small intestine morphology","volume":"52","author":"Zarrin-Kavyani","year":"2020","journal-title":"Trop. Anim. Health Prod."},{"issue":"1","key":"10.1016\/j.psj.2024.104444_bib0064","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.cmet.2019.10.013","article-title":"STAT3 activation-induced fatty acid oxidation in CD8(+) T effector cells is critical for obesity-promoted breast tumor growth","volume":"31","author":"Zhang","year":"2020","journal-title":"Cell Metab"},{"issue":"3","key":"10.1016\/j.psj.2024.104444_bib0065","first-page":"697","article-title":"S100A11 promotes liver steatosis via FOXO1-mediated autophagy and lipogenesis","volume":"11","author":"Zhang","year":"2021","journal-title":"Cell Mol. Gastroenter."},{"issue":"24","key":"10.1016\/j.psj.2024.104444_bib0066","doi-asserted-by":"crossref","first-page":"15690","DOI":"10.3390\/ijms232415690","article-title":"Metabolomics and proteomics characterizing hepatic reactions to dietary linseed oil in duck","volume":"23","author":"Zhang","year":"2022","journal-title":"Int. J. Mol. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124010228?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124010228?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:49:16Z","timestamp":1777438156000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124010228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":66,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0032579124010228"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104444","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Threonine modulates the STAT3-SCD1 pathway to reduce fatty acid metabolism in duck hepatocytes","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104444","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104444"}}