{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:46:28Z","timestamp":1786995988991,"version":"build-2736575974"},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University Teachers College","doi-asserted-by":"publisher","award":["RSPD2024R731"],"award-info":[{"award-number":["RSPD2024R731"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.psj.2024.104491","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T12:27:44Z","timestamp":1730464064000},"page":"104491","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Dietary supplementation of lysozyme can improve growth rate, laying performance, blood biochemistry, and mRNA levels of some related genes in different plumage-colored quails"],"prefix":"10.1016","volume":"104","author":[{"given":"Ibrahim","family":"Elkhaiat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seham","family":"El-Kassas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karima","family":"El-Naggar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safaa","family":"Abdo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham K.","family":"Shalaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud M.","family":"Azzam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Di Cerbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Alagawany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyad Y.","family":"Nofal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.104491_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101696","article-title":"Alternatives to antibiotics for organic poultry production: types, modes of action and impacts on bird's health and production","volume":"101","author":"Abd El-Hack","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0002","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185153","article-title":"Exogenous dietary lysozyme improves the growth performance and gut microbiota in broiler chickens targeting the antioxidant and non-specific immunity mRNA expression","volume":"12","author":"Abdel-Latif","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2024.104491_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10495398.2023.2187411","article-title":"Hematology profile, digestive enzymes, thyroid hormones, productivity, and nitrogen balance of growing male rabbits supplemented with exogenous dietary lysozyme","author":"Abdelazeem","year":"2023","journal-title":"Anim. Biotechnol."},{"key":"10.1016\/j.psj.2024.104491_bib0004","first-page":"111","article-title":"Comparison of three lines of Japanese quails revealed a remarkable role of plumage color in the productivity performance determination","volume":"8","author":"Al-Kafajy","year":"2018","journal-title":"J. World Poult. Res"},{"key":"10.1016\/j.psj.2024.104491_bib0005","doi-asserted-by":"crossref","first-page":"832","DOI":"10.14202\/vetworld.2016.832-836","article-title":"Body weight, egg production, and egg quality traits of gray, brown, and white varieties of Japanese quail (Coturnix coturnix japonica) in coastal climatic condition of Odisha","volume":"9","author":"Bagh","year":"2016","journal-title":"Vet. World."},{"key":"10.1016\/j.psj.2024.104491_bib0006","series-title":"Bancroft's Theory and Practice of Histological Techniques","author":"Bancroft","year":"2013"},{"key":"10.1016\/j.psj.2024.104491_bib0007","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1677\/joe.0.1680297","article-title":"Insulin-like growth factors and body growth in chickens divergently selected for high or low growth rate","volume":"168","author":"Beccavin","year":"2001","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.psj.2024.104491_bib0008","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1128\/iai.16.3.974-982.1977","article-title":"Role of lysozyme in the microbicidal activity of rat alveolar macrophages","volume":"16","author":"Biggar","year":"1977","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psj.2024.104491_bib0009","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/ps\/84.4.634","article-title":"Antibiotic growth promoters in agriculture: history and mode of action","volume":"84","author":"Dibner","year":"2005","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0010","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.brainres.2005.04.034","article-title":"Mode of leptin action in chicken hypothalamus","volume":"1047","author":"Dridi","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.psj.2024.104491_bib0011","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.3390\/ani11061731","article-title":"The influence of chicken egg lysozyme or zinc-bacitracin antibiotic on the growth performance, antibacterial capacity, blood profiles, and antioxidative status of rabbits: a comparative study","volume":"11","author":"EL-Deep","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.psj.2024.104491_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.579576","article-title":"The influence of dietary chicken egg lysozyme on the growth performance, blood health, and resistance against escherichia coli in the growing rabbits' cecum","volume":"7","author":"EL-Deep","year":"2020","journal-title":"Frontiers in Veterinary Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102520","article-title":"Impacts of supplemental Ginkgo biloba oil on broilers' growth, blood indices, intestinal and hepatic morphology and expression of growth-related genes","author":"El-Kasrawy","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0014","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jtherbio.2018.10.009","article-title":"Ameliorative effect of dietary supplementation of copper oxide nanoparticles on inflammatory and immune reponses in commercial broiler under normal and heat-stress housing conditions","volume":"78","author":"El-Kassas","year":"2018","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.psj.2024.104491_bib0015","first-page":"471","article-title":"Expression and regulation of cholecystokinin receptor in the chicken's immune organs and cells","volume":"7","author":"El-Kassas","year":"2016","journal-title":"J. Clin. Cell Immunol."},{"key":"10.1016\/j.psj.2024.104491_bib0016","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jtherbio.2019.07.004","article-title":"Role of gamma-aminobutyric acid in regulating feed intake in commercial broilers reared under normal and heat stress conditions","volume":"84","author":"El-Naggar","year":"2019","journal-title":"J. Therm. Biol"},{"key":"10.1016\/j.psj.2024.104491_bib0017","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11250-023-03604-5","article-title":"Assessment of variations in productive performance of two different plumage color varieties of Japanese quail and their reciprocal crosses","volume":"55","author":"Elkhaiat","year":"2023","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.psj.2024.104491_bib0018","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1007\/s12011-020-02422-2","article-title":"Reducing the abundance of harmful bacteria of rooftop tank\u2013stored drinking water using silver nanoparticles and acetic acid and its impact on japanese quail growth performances","volume":"199","author":"Elsaidy","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2024.104491_bib0019","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nn1214","article-title":"Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system","volume":"7","author":"Fan","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.psj.2024.104491_bib0020","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.3390\/antibiotics10121534","article-title":"Applications of lysozyme, an innate immune defense factor, as an alternative antibiotic","volume":"10","author":"Ferraboschi","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.psj.2024.104491_bib0021","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.chroma.2005.06.083","article-title":"Hen egg white fractionation by ion-exchange chromatography","volume":"1090","author":"Gu\u00e9rin-Dubiard","year":"2005","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.psj.2024.104491_bib0022","doi-asserted-by":"crossref","DOI":"10.3390\/foods6070053","article-title":"Future protein supply and demand: strategies and factors influencing a sustainable equilibrium","volume":"6","author":"Henchion","year":"2017","journal-title":"Foods"},{"key":"10.1016\/j.psj.2024.104491_bib0023","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.livsci.2008.01.014","article-title":"Effects of soy-lecithin on lipid metabolism and hepatic expression of lipogenic genes in broiler chickens","volume":"118","author":"Huang","year":"2008","journal-title":"Livest. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0024","doi-asserted-by":"crossref","first-page":"241","DOI":"10.5455\/jabet.2020.d130","article-title":"Dietary acidifier and lysozyme improve growth performances and hemato-biochemical profile in broiler chicken","volume":"3","author":"Ibne Khalil","year":"2020","journal-title":"J Adv Biotechnol Exp Ther"},{"key":"10.1016\/j.psj.2024.104491_bib0025","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1021\/jf960133x","article-title":"Partially unfolded lysozyme at neutral pH agglutinates and kills gram-negative and gram-positive bacteria through membrane damage mechanism","volume":"44","author":"Ibrahim","year":"1996","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2024.104491_bib0026","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1590\/S1806-92902015001100003","article-title":"Comparison of fattening performance, carcass characteristics, and egg quality characteristics of Japanese quails with different feather colors","volume":"44","author":"Inci","year":"2015","journal-title":"Rev. Bras. Zootec."},{"key":"10.1016\/j.psj.2024.104491_bib0027","doi-asserted-by":"crossref","first-page":"397","DOI":"10.5713\/ajas.1996.397","article-title":"Influence of dried Bacillus substillis and lactobacilli cultures on intestinal microflora and performance in broilers","volume":"9","author":"Jin","year":"1996","journal-title":"Asian-Australas J Anim Sci"},{"key":"10.1016\/j.psj.2024.104491_bib0028","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.5713\/ajas.2010.10329","article-title":"The endocrine regulation of chicken growth","volume":"23","author":"Kim","year":"2010","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0029","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.3390\/ani11041170","article-title":"Use of corn silk meal in broiler diet: effect on growth performance, blood biochemistry, immunological responses, and growth-related gene expression","volume":"11","author":"Kirrella","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.psj.2024.104491_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102360","article-title":"Growing and laying performance of two different-plumage color Japanese quail varieties supplemented with corn silk in their diet","volume":"102","author":"Kirrella","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0031","doi-asserted-by":"crossref","first-page":"747","DOI":"10.5713\/ajas.2005.747","article-title":"Nutritional and tissue specificity of IGF-I and IGFBP-2 gene expression in growing chickens - A Review","volume":"18","author":"Kita","year":"2005","journal-title":"Asian Australas. J. Anim. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0032","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/03079450903447404","article-title":"Exogenous lysozyme influences Clostridium perfringens colonization and intestinal barrier function in broiler chickens","volume":"39","author":"Liu","year":"2010","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2024.104491_bib0033","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2024.104491_bib0034","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/S1004-9541(11)60068-2","article-title":"Isolation of lysozyme from chicken egg white using polyacrylamide-based cation-exchange cryogel","volume":"19","author":"Luding","year":"2011","journal-title":"Chin. J. Chem. Eng."},{"key":"10.1016\/j.psj.2024.104491_bib0035","first-page":"466","article-title":"Effects of lysozyme on the growth performance, nutrient digestibility, intestinal barrier, and microbiota of weaned pigs fed diets containing spray-dried whole egg or albumen powder","volume":"97","author":"Ma","year":"2017","journal-title":"Can. J. Anim. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0036","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.2527\/jas.2011-4297","article-title":"Granulated lysozyme as an alternative to antibiotics improves growth performance and small intestinal morphology of 10-day-old pigs","volume":"90","author":"May","year":"2012","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0037","doi-asserted-by":"crossref","DOI":"10.3390\/foods12091776","article-title":"Antibiotic-free poultry meat consumption and its determinants","volume":"12","author":"Mohammadi","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.psj.2024.104491_bib0038","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1007\/s13197-017-2881-4","article-title":"Performance, carcass traits, meat quality and amino acid profile of different Japanese quails strains","volume":"54","author":"Nasr","year":"2017","journal-title":"J. Food Sci. Technol."},{"key":"10.1016\/j.psj.2024.104491_bib0039","series-title":"Nutrient requirements of poultry","year":"1994"},{"key":"10.1016\/j.psj.2024.104491_bib0040","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1093\/ps\/82.6.907","article-title":"Genetic regulation of feed intake and energy balance in poultry","volume":"82","author":"Richards","year":"2003","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104491_bib0041","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1365-2109.2007.01883.x","article-title":"Lysozyme: an important defence molecule of fish innate immune system","volume":"39","author":"Saurabh","year":"2008","journal-title":"Aquaculture Research"},{"key":"10.1016\/j.psj.2024.104491_bib0042","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ygcen.2009.04.013","article-title":"Perspectives on the endocrinology of poultry growth and metabolism","volume":"163","author":"Scanes","year":"2009","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.psj.2024.104491_bib0043","doi-asserted-by":"crossref","unstructured":"Sindaye, D., Z. Xiao, C. Wen, K. Yang, L. Zhang, P. Liao, F. Zhang, Z. Xin, S. He, S. Ye, D. Guo, S. Hang, S. Zeid, and B. Deng. 2023. Exploring the effects of lysozyme dietary supplementation on laying hens: performance, egg quality, and immune response. 10. 10.3389\/fvets.2023.1273372.","DOI":"10.3389\/fvets.2023.1273372"},{"key":"10.1016\/j.psj.2024.104491_bib0044","first-page":"43","article-title":"[The influence of lysozyme dimmer on chosen parameters of blood in healthy rabbits]","volume":"38","author":"Szymonowicz","year":"2008","journal-title":"Polim. Med."},{"key":"10.1016\/j.psj.2024.104491_bib0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216748","article-title":"Effects of dietary supplementation with lysozyme on the structure and function of the cecal microbiota in broiler chickens","volume":"14","author":"Xia","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2024.104491_bib0046","doi-asserted-by":"crossref","DOI":"10.3390\/foods11223567","article-title":"Extraction and Characterization of Lysozyme from Salted Duck Egg White","volume":"11","author":"Yao","year":"2022","journal-title":"Foods"},{"key":"10.1016\/j.psj.2024.104491_bib0047","first-page":"375","article-title":"External and internal egg quality characteristics in Japanese quails of different plumage color lines","volume":"9","author":"Y\u0131lmaz","year":"2011","journal-title":"J. Food Agric. Environ."},{"key":"10.1016\/j.psj.2024.104491_bib0048","first-page":"54","article-title":"Effects of dietary supplementation with lysozyme on performance, egg quality and serum biochemical indexes of laying hens","volume":"19","author":"Zaili","year":"2020","journal-title":"Feed Industry"},{"key":"10.1016\/j.psj.2024.104491_bib0049","article-title":"Progress on gut health maintenance and antibiotic alternatives in broiler chicken production","volume":"8","author":"Zhu","year":"2021","journal-title":"Fronteries Nutrition"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124010691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124010691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:46:48Z","timestamp":1758998808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124010691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0032579124010691"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104491","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary supplementation of lysozyme can improve growth rate, laying performance, blood biochemistry, and mRNA levels of some related genes in different plumage-colored quails","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104491","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104491"}}