{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:32:00Z","timestamp":1788899520611,"version":"build-2803163510"},"reference-count":68,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T00:00:00Z","timestamp":1732924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.psj.2024.104616","type":"journal-article","created":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T09:54:12Z","timestamp":1733046852000},"page":"104616","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus"],"prefix":"10.1016","volume":"104","author":[{"given":"Futing","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawen","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ainul","family":"Zahra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingkai","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongbo","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingshuo","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunwei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhannan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.104616_bib0001","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s12985-020-01465-0","article-title":"CD83 expression regulates antibody production in response to influenza A virus infection","volume":"17","author":"Akauliya","year":"2020","journal-title":"Virol. J."},{"key":"10.1016\/j.psj.2024.104616_bib0002","doi-asserted-by":"crossref","first-page":"24963","DOI":"10.1021\/acsami.5b08811","article-title":"Bacterial nanobioreactors\u2013directing enzyme packaging into Bacterial outer membrane vesicles","volume":"7","author":"Alves","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.psj.2024.104616_bib0003","doi-asserted-by":"crossref","first-page":"3990","DOI":"10.1016\/j.vaccine.2011.03.066","article-title":"Protective cellular responses elicited by vaccination with influenza nucleoprotein delivered by a live recombinant attenuated Salmonella vaccine","volume":"29","author":"Ashraf","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2024.104616_bib0004","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1046\/j.1462-5822.2001.00087.x","article-title":"SifA permits survival and replication of Salmonella typhimurium in murine macrophages","volume":"3","author":"Brumell","year":"2001","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0005","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1128\/jb.89.1.28-40.1965","article-title":"Chromosomal aberrations associated with mutations to bacteriophage resistance in Escherichia Coli","volume":"89","author":"Curtis","year":"1965","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.psj.2024.104616_bib0006","first-page":"427","article-title":"Vaccines to control Salmonella in poultry","volume":"67","author":"Curtiss","year":"2024","journal-title":"Avian Dis."},{"key":"10.1016\/j.psj.2024.104616_bib0007","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.vetimm.2010.07.010","article-title":"Flow cytometric assessment of antigen-specific proliferation in peripheral chicken T cells by CFSE dilution","volume":"138","author":"Dalgaard","year":"2010","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.psj.2024.104616_bib0008","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1016\/j.vaccine.2006.04.008","article-title":"Protection against H1, H5, H6 and H9 influenza A infection with liposomal matrix 2 epitope vaccines","volume":"24","author":"Ernst","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2024.104616_bib0009","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.virusres.2004.02.030","article-title":"A \"universal\" human influenza A vaccine","volume":"103","author":"Fiers","year":"2004","journal-title":"Virus Res."},{"key":"10.1016\/j.psj.2024.104616_bib0010","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.molimm.2019.04.003","article-title":"Changes in apoptosis, proliferation and T lymphocyte subtype on thymic cells of SPF chickens infected with reticuloendotheliosis virus","volume":"111","author":"Fu","year":"2019","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.psj.2024.104616_bib0011","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.micpath.2017.12.050","article-title":"Recombinant M2e-HA2 fusion protein induced immunity responses against intranasally administered H9N2 influenza virus","volume":"115","author":"Golchin","year":"2018","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.psj.2024.104616_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2023.105093","article-title":"Mechanisms of type I interferon production by chicken TLR21","volume":"151","author":"Guabiraba","year":"2024","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.psj.2024.104616_bib0013","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/90434","article-title":"Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin","volume":"8","author":"Han","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.psj.2024.104616_bib0014","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.3382\/ps\/pew068","article-title":"Prevalence of avian respiratory viruses in broiler flocks in Egypt","volume":"95","author":"Hassan","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0015","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.virol.2021.12.001","article-title":"Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag\/SpyCatcher technology","volume":"566","author":"Heinimaki","year":"2022","journal-title":"Virology"},{"key":"10.1016\/j.psj.2024.104616_bib0016","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12943-022-01515-x","article-title":"Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer","volume":"21","author":"Huang","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.psj.2024.104616_bib0017","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.rvsc.2016.12.002","article-title":"Targeting antigens to Dec-205 on dendritic cells induces a higher immune response in chickens: hemagglutinin of avian influenza virus example","volume":"111","author":"Jauregui-Zuniga","year":"2017","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2023.109875","article-title":"Chicken dendritic cell-targeting nanobodies mediated improved protective effects against H9N2 influenza virus challenge in a homologous sequential immunization study","volume":"285","author":"Jia","year":"2023","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0019","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216871","article-title":"Influenza M2 virus-like particle vaccination enhances protection in combination with avian influenza HA VLPs","volume":"14","author":"Kang","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2024.104616_bib0020","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1038\/sj.onc.1210375","article-title":"Antibody-targeted vaccines","volume":"26","author":"Keler","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.psj.2024.104616_bib0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010755","article-title":"Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle","volume":"18","author":"Kim","year":"2022","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.psj.2024.104616_bib0022","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.antiviral.2013.06.010","article-title":"Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection","volume":"99","author":"Kim","year":"2013","journal-title":"Antiviral Res."},{"key":"10.1016\/j.psj.2024.104616_bib0023","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/mt.2012.246","article-title":"Virus-like particles containing multiple M2 extracellular domains confer improved cross-protection against various subtypes of influenza virus","volume":"21","author":"Kim","year":"2013","journal-title":"Mol. Ther."},{"key":"10.1016\/j.psj.2024.104616_bib0024","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1259989","article-title":"Surface toll-like receptor 9 on immune cells and its immunomodulatory effect","volume":"14","author":"Kou","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2024.104616_bib0025","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1216364","article-title":"SpyTag\/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion","volume":"13","author":"Lampinen","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0026","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.molimm.2019.07.022","article-title":"Identification and tissue-expression profiling of novel chicken c-type lectin-like domain containing proteins as potential targets for carbohydrate-based vaccine strategies","volume":"114","author":"Larsen","year":"2019","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.psj.2024.104616_bib0027","doi-asserted-by":"crossref","first-page":"7772","DOI":"10.7150\/thno.34941","article-title":"Theranostics in immuno-oncology using nanobody derivatives","volume":"9","author":"Lecocq","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.psj.2024.104616_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2021.109106","article-title":"H7N9 influenza virus-like particle based on BEVS protects chickens from lethal challenge with highly pathogenic H7N9 avian influenza virus","volume":"258","author":"Li","year":"2021","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0029","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/08820139.2020.1834579","article-title":"Identification of linear peptide immunogens with verified broad-spectrum immunogenicity from the conserved regions within the hemagglutinin stem domain of H1N1 Influenza Virus","volume":"51","author":"Li","year":"2022","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.psj.2024.104616_bib0030","doi-asserted-by":"crossref","first-page":"649","DOI":"10.3390\/vaccines11030649","article-title":"CpG 1018 is an effective adjuvant for influenza nucleoprotein","volume":"11","author":"Li","year":"2023","journal-title":"Vaccines (Basel)"},{"key":"10.1016\/j.psj.2024.104616_bib0031","article-title":"Immunoprotection of FliBc chimeric fiber2 fusion proteins targeting dendritic cells against Fowl adenovirus serotype 4 infection","volume":"103","author":"Li","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0032","doi-asserted-by":"crossref","first-page":"6783","DOI":"10.1016\/j.vaccine.2014.10.013","article-title":"Enhanced immune response of BMDCs pulsed with H9N2 AIV and CpG","volume":"32","author":"Lin","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2024.104616_bib0033","doi-asserted-by":"crossref","first-page":"e00759","DOI":"10.1128\/IAI.00759-19","article-title":"Dendritic cells targeting Lactobacillus plantarum strain NC8 with a surface-displayed single-chain variable fragment of CD11c induce an antigen-specific protective cellular immune response","volume":"88","author":"Liu","year":"2020","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psj.2024.104616_bib0034","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3390\/biom14010133","article-title":"Salmonella typhimurium vaccine candidate delivering infectious bronchitis virus S1 protein to induce protection","volume":"14","author":"Liu","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.psj.2024.104616_bib0035","first-page":"690","article-title":"Cloning of full-length genes of H5N1 subtype Avian influenza virus strain A\/duck\/Shandong\/093\/2004 and analysis of the sequences","volume":"45","author":"Long","year":"2005","journal-title":"Wei Sheng Wu Xue Bao"},{"key":"10.1016\/j.psj.2024.104616_bib0036","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-1-4614-0980-9_9","article-title":"Influenza virus entry","volume":"726","author":"Luo","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.psj.2024.104616_bib0037","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1038\/s41467-018-03931-4","article-title":"Modular assembly of proteins on nanoparticles","volume":"9","author":"Ma","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2024.104616_bib0038","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.chom.2014.11.011","article-title":"PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection","volume":"17","author":"McEwan","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.psj.2024.104616_bib0039","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.1039\/D3BM00305A","article-title":"Delivery of gold nanoparticle-conjugated M2e influenza vaccine in mice using coated microneedles","volume":"11","author":"Nesovic","year":"2023","journal-title":"Biomaterials Science"},{"key":"10.1016\/j.psj.2024.104616_bib0040","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/nrc3258","article-title":"Cancer immunotherapy via dendritic cells","volume":"12","author":"Palucka","year":"2012","journal-title":"Nature Reviews. Cancer"},{"key":"10.1016\/j.psj.2024.104616_bib0041","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/s12951-022-01357-1","article-title":"Chimeric virus-like particles presenting tumour-associated MUC1 epitope result in high titers of specific IgG antibodies in the presence of squalene oil-in-water adjuvant: towards safe cancer immunotherapy","volume":"20","author":"Panasiuk","year":"2022","journal-title":"J Nanobiotechnology"},{"key":"10.1016\/j.psj.2024.104616_bib0042","article-title":"Intranasal Nanovaccine confers homo- and hetero-subtypic influenza protection","volume":"14","author":"Qi","year":"2018","journal-title":"Small"},{"key":"10.1016\/j.psj.2024.104616_bib0043","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/anie.202009663","article-title":"Overcoming symmetry mismatch in vaccine nanoassembly through spontaneous amidation","volume":"60","author":"Rahikainen","year":"2021","journal-title":"Angew. Chem. Int. Ed Engl."},{"key":"10.1016\/j.psj.2024.104616_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.jviromet.2020.113938","article-title":"Immunization of turkeys with a DNA vaccine expressing the haemagglutinin gene of low pathogenic avian influenza virus subtype H9N2","volume":"284","author":"Shehata","year":"2020","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.psj.2024.104616_bib0045","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/s41541-022-00486-w","article-title":"A CpG 1018 adjuvanted neuraminidase vaccine provides robust protection from influenza virus challenge in mice","volume":"7","author":"Strohmeier","year":"2022","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.psj.2024.104616_bib0046","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41541-022-00498-6","article-title":"A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine","volume":"7","author":"Subbiah","year":"2022","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.psj.2024.104616_bib0047","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.2147\/IJN.S297631","article-title":"Nanobody: a small antibody with big implications for tumor therapeutic strategy","volume":"16","author":"Sun","year":"2021","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.psj.2024.104616_bib0048","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s13238-014-0111-7","article-title":"H9N2 influenza virus in China: a cause of concern","volume":"6","author":"Sun","year":"2015","journal-title":"Protein & Cell"},{"key":"10.1016\/j.psj.2024.104616_bib0049","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/s41467-020-20654-7","article-title":"A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses","volume":"12","author":"Tan","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2024.104616_bib0050","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.jconrel.2023.11.008","article-title":"Simultaneous dendritic cells targeting and effective endosomal escape enhance sialic acid-modified mRNA vaccine efficacy and reduce side effects","volume":"364","author":"Tang","year":"2023","journal-title":"Journal of Controlled Release: Official journal of the Controlled Release Society"},{"key":"10.1016\/j.psj.2024.104616_bib0051","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/1487651","article-title":"The presence of poultry influenza strains in two live bird markets near the East-West boundary of Vietnam","volume":"2020","author":"Tran","year":"2020","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.psj.2024.104616_bib0052","article-title":"Genetic evolution characteristics of genotype G57 Virus, A dominant genotype of H9N2 Avian Influenza Virus","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0053","article-title":"A triple-sugar regulated Salmonella vaccine protects against Clostridium perfringens-induced necrotic enteritis in broiler chickens","volume":"101","author":"Wang","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2021.109238","article-title":"Recombinant HA1-DeltafliC enhances adherence to respiratory epithelial cells and promotes the superiorly protective immune responses against H9N2 influenza virus in chickens","volume":"262","author":"Wang","year":"2021","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0055","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.nano.2018.11.009","article-title":"Ferritin nanoparticle-based SpyTag\/SpyCatcher-enabled click vaccine for tumor immunotherapy","volume":"16","author":"Wang","year":"2019","journal-title":"Nanomedicine: Nanotechnology, Biology, and Medicine"},{"key":"10.1016\/j.psj.2024.104616_bib0056","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2022.109474","article-title":"Protection against genotype VII Newcastle disease virus challenge by a minicircle DNA vaccine coexpressing F protein and chicken IL-18 adjuvant","volume":"270","author":"Wang","year":"2022","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2024.104616_bib0057","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/289373a0","article-title":"Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation","volume":"289","author":"Wiley","year":"1981","journal-title":"Nature"},{"key":"10.1016\/j.psj.2024.104616_bib0058","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101791","article-title":"Poly (lactic-co-glycolic acid) nanoparticle-based vaccines delivery systems as a novel adjuvant for H9N2 antigen enhance immune responses","volume":"101","author":"Wusiman","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0059","doi-asserted-by":"crossref","first-page":"7670","DOI":"10.1016\/j.vaccine.2011.07.139","article-title":"A candidate dual vaccine against influenza and noroviruses","volume":"29","author":"Xia","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2024.104616_bib0060","doi-asserted-by":"crossref","first-page":"12122","DOI":"10.1038\/s41598-022-16378-x","article-title":"Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies","volume":"12","author":"Xu","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2024.104616_bib0061","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1063129","article-title":"Evaluation of dendritic cell-targeting T7 phages as a vehicle to deliver avian influenza virus H5 DNA vaccine in SPF chickens","volume":"13","author":"Xu","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2024.104616_bib0062","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102925","article-title":"Enhance immune response to H9 AIV DNA vaccine based on polygene expression and DGL nanoparticle encapsulation","volume":"102","author":"Xu","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104616_bib0063","doi-asserted-by":"crossref","first-page":"3102","DOI":"10.1099\/vir.0.2008\/005652-0","article-title":"Characterization of H9N2 influenza viruses isolated from vaccinated flocks in an integrated broiler chicken operation in eastern China during a 5 year period (1998-2002)","volume":"89","author":"Zhang","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.psj.2024.104616_bib0064","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12985-023-02044-9","article-title":"Vaccination with recombinant Lactococcus lactis expressing HA1-IgY Fc fusion protein provides protective mucosal immunity against H9N2 avian influenza virus in chickens","volume":"20","author":"Zhang","year":"2023","journal-title":"Virol. J."},{"key":"10.1016\/j.psj.2024.104616_bib0065","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1021\/acs.molpharmaceut.2c00805","article-title":"Cationic nanoparticle-stabilized vaccine delivery system for the H9N2 vaccine to promote immune response in chickens","volume":"20","author":"Zhang","year":"2023","journal-title":"Mol Pharm"},{"key":"10.1016\/j.psj.2024.104616_bib0066","doi-asserted-by":"crossref","DOI":"10.3390\/vaccines9010022","article-title":"Salmonella vaccine vector system for foot-and-Mouth disease virus and evaluation of its efficacy with virus-like particles","volume":"9","author":"Zhi","year":"2021","journal-title":"Vaccines"},{"key":"10.1016\/j.psj.2024.104616_bib0067","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/JLB.3MR1220-748RRRRR","article-title":"The role of bacterial DNA containing CpG motifs in diseases","volume":"109","author":"Zhou","year":"2021","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.psj.2024.104616_bib0068","doi-asserted-by":"crossref","first-page":"6441","DOI":"10.3390\/molecules28186441","article-title":"Nanoparticles carrying conserved regions of influenza A hemagglutinin, nucleoprotein, and M2 protein elicit a strong humoral and T cell immune response and protect animals from infection","volume":"28","author":"Zykova","year":"2023","journal-title":"Molecules"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124011945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124011945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:40:40Z","timestamp":1758998440000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124011945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0032579124011945"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104616","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104616","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104616"}}