{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:47:45Z","timestamp":1792000065269,"version":"4.4.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011798","name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011798","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.psj.2024.104692","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T02:52:01Z","timestamp":1734490321000},"page":"104692","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Transcriptomic insight into the underlying mechanism of induced molting on reproductive remodeling, performance and egg quality in laying hen"],"prefix":"10.1016","volume":"104","author":[{"given":"Pengyun","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuguang","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9400-009X","authenticated-orcid":false,"given":"Jilan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoke","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinying","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqi","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8117-6232","authenticated-orcid":false,"given":"Yunlei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2024.104692_bib0001","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.anireprosci.2007.02.020","article-title":"Reproductive tissue regression: involvement of caspases, inducible nitric oxide synthase and nitric oxide during moulting in White Leghorn hens","volume":"104","author":"Anish","year":"2008","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0002","doi-asserted-by":"crossref","first-page":"48","DOI":"10.4161\/cam.22826","article-title":"The laminin family","volume":"7","author":"Aumailley","year":"2013","journal-title":"Cell Adhes. Migr."},{"key":"10.1016\/j.psj.2024.104692_bib0003","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/ps\/82.6.971","article-title":"The physiology of induced molting","volume":"82","author":"Berry","year":"2003","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0004","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.tem.2005.09.001","article-title":"Estrogen action: revitalization of the chick oviduct model","volume":"16","author":"Dougherty","year":"2005","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.psj.2024.104692_bib0005","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.theriogenology.2016.12.023","article-title":"Expression of genes involved in BMP and estrogen signaling and AMPK production can be important factors affecting total number of antral follicles in ewes","volume":"91","author":"Foroughinia","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2024.104692_bib0006","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.acthis.2015.10.003","article-title":"Immunohistochemical localization of progesterone receptor isoforms and estrogen receptor alpha in the chicken oviduct magnum during development","volume":"117","author":"Gonz\u00e1lez-Mor\u00e1n","year":"2015","journal-title":"Acta Histochem"},{"key":"10.1016\/j.psj.2024.104692_bib0007","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.bbrc.2016.08.071","article-title":"Changes in progesterone receptor isoforms expression and in the morphology of the oviduct magnum of mature laying and aged nonlaying hens","volume":"478","author":"Gonz\u00e1lez-Mor\u00e1n","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.psj.2024.104692_bib0008","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3923\/ajpsaj.2011.13.20","article-title":"Effect of force molting programs on egg production and quality of laying hens","volume":"5","author":"Hassanien","year":"2011","journal-title":"Asian J. Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0009","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/ps\/76.1.67","article-title":"Involvement of apoptosis and lysosomal hydrolase activity in the oviducal regression during induced molting in chickens: a cytochemical study for end labeling of fragmented DNA and acid phosphatase","volume":"76","author":"Heryanto","year":"1997","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0010","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1743-7075-7-47","article-title":"Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones","volume":"7","author":"Hu","year":"2010","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.psj.2024.104692_bib0011","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1016\/j.psj.2019.12.053","article-title":"Improving effects of epimedium flavonoids on the selected reproductive features in layer hens after forced molting","volume":"99","author":"Huo","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0012","doi-asserted-by":"crossref","first-page":"e76784","DOI":"10.1371\/journal.pone.0076784","article-title":"Recrudescence mechanisms and gene expression profile of the reproductive tracts from chickens during the molting period","volume":"8","author":"Jeong","year":"2013","journal-title":"PLOS ONE"},{"key":"10.1016\/j.psj.2024.104692_bib0013","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0092-8674(00)80374-8","article-title":"Cloning and crystal structure of hematopoietic prostaglandin D synthase","volume":"90","author":"Kanaoka","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.psj.2024.104692_bib0014","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/ps\/84.11.1750","article-title":"Melengestrol acetate in experimental diets as an effective alternative to induce a decline in egg production and reversible regression of the reproductive tract in laying hens I. Determining an effective concentration of melengestrol acetate","volume":"84","author":"Koch","year":"2005","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0015","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1002\/jat.4573","article-title":"Nitrophenols disrupt the expression and activity of biotransformation enzymes (CYP3A and COMT) in chicken ovarian follicles in vivo and in vitro","volume":"44","author":"Kozubek","year":"2024","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.psj.2024.104692_bib0016","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1210\/en.2002-220446","article-title":"11\u03b2-Hydroxysteroid dehydrogenase complementary deoxyribonucleic acid in rainbow trout: cloning, sites of expression, and seasonal changes in gonads","volume":"144","author":"Kusakabe","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2024.104692_bib0017","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1210\/en.2016-1851","article-title":"The steroid metabolome in the isolated ovarian follicle and its response to androgen exposure and antagonism","volume":"158","author":"Lebbe","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2024.104692_bib0018","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1186\/s12864-017-3915-z","article-title":"Histological and transcriptomic effects of 17\u03b1-methyltestosterone on zebrafish gonad development","volume":"18","author":"Lee","year":"2017","journal-title":"BMC Genomics"},{"key":"10.1016\/j.psj.2024.104692_bib0019","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.exger.2013.10.006","article-title":"Increased Th17 differentiation in aged mice is significantly associated with high IL-1\u03b2 level and low IL-2 expression","volume":"49","author":"Lim","year":"2014","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.psj.2024.104692_bib0020","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1093\/bioinformatics\/bti430","article-title":"Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary","volume":"21","author":"Mao","year":"2005","journal-title":"Bioinforma. Oxf. Engl."},{"key":"10.1016\/j.psj.2024.104692_bib0021","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1207\/s15327604jaws0901_2","article-title":"Effects of induced molting on the well-being of egg-laying hens","volume":"9","author":"McCowan","year":"2006","journal-title":"J. Appl. Anim. Welf. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0022","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ygcen.2013.09.007","article-title":"Increased hepatic yolk precursor synthesis, secretion and facilitated uptake by follicles are involved in the rejuvenation of reproductive performance of molted hens (Gallus gallus domesticus)","volume":"194","author":"Meng","year":"2013","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.psj.2024.104692_bib0023","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1210\/mend.16.6.0855","article-title":"Tissue-protective effects of estrogen involve regulation of caspase gene expression","volume":"16","author":"Monroe","year":"2002","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.psj.2024.104692_bib0024","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1016\/S0021-9258(19)44193-8","article-title":"Regulation of protein synthesis in chick oviduct. IV, role of testosterone","volume":"248","author":"Palmiter","year":"1973","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.psj.2024.104692_bib0025","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a004978","article-title":"The Collagen Family","volume":"3","author":"Ricard-Blum","year":"2011","journal-title":"COLD SPRING Harb. Perspect. Biol."},{"key":"10.1016\/j.psj.2024.104692_bib0026","doi-asserted-by":"crossref","first-page":"7282","DOI":"10.1073\/pnas.96.13.7282","article-title":"A functional bone morphogenetic protein system in the ovary","volume":"96","author":"Shimasaki","year":"1999","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0027","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jri.2006.05.001","article-title":"Cytokines in reproductive remodeling of molting White Leghorn hens","volume":"73","author":"Sundaresan","year":"2007","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.psj.2024.104692_bib0028","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1093\/ps\/81.3.327","article-title":"Effect of induced molting on albumen quality, hatchability, and chick body weight from broiler breeders","volume":"81","author":"Tona","year":"2002","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0029","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0090-6980(02)00042-4","article-title":"Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence","volume":"68\u201369","author":"Urade","year":"2002","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1016\/j.psj.2024.104692_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102820","article-title":"Effect of induced molting on ovarian function remodeling in laying hens","volume":"102","author":"Wang","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2024.104692_bib0031","article-title":"The role of the transcription factor EGR1 in cancer","volume":"11","author":"Wang","year":"2021","journal-title":"Front. Oncol."},{"key":"10.1016\/j.psj.2024.104692_bib0032","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1590\/S0100-879X2003000800001","article-title":"Dimensions and dynamics in integrin function","volume":"36","author":"Yamada","year":"2003","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.psj.2024.104692_bib0033","doi-asserted-by":"crossref","first-page":"R14","DOI":"10.1186\/gb-2010-11-2-r14","article-title":"Gene ontology analysis for RNA-seq: accounting for selection bias","volume":"11","author":"Young","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.psj.2024.104692_bib0034","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.3390\/genes12111767","article-title":"Transcriptomic analysis of laying hens revealed the role of aging-related genes during forced molting","volume":"12","author":"Zhang","year":"2021","journal-title":"Genes"},{"key":"10.1016\/j.psj.2024.104692_bib0035","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3390\/genes13010089","article-title":"Understanding transcriptomic and serological differences between forced molting and natural molting in laying hens","volume":"13","author":"Zhang","year":"2022","journal-title":"Genes"},{"key":"10.1016\/j.psj.2024.104692_bib0036","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1002\/jcb.26279","article-title":"Hsd3b2 associated in modulating steroid hormone synthesis pathway regulates the differentiation of chicken embryonic stem cells into spermatogonial stem cells","volume":"119","author":"Zhang","year":"2018","journal-title":"J. Cell. Biochem."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124012707?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579124012707?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T06:44:52Z","timestamp":1776667492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579124012707"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0032579124012707"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2024.104692","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptomic insight into the underlying mechanism of induced molting on reproductive remodeling, performance and egg quality in laying hen","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2024.104692","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104692"}}